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Cited by 145Adrenal and Paraganglionic TumorsRenal cell carcinoma treatmentAdrenal Hormones and Disorders

The DOI matches its Crossref record; 20 of the 20 references it cites were found in a registry or an index.

The Cleveland Clinic Experience with Adrenal Cortical Carcinoma

Bodie, Barry, Novick, Andrew C., Pontes, J. Edson, Straffon, Ralph A., Montie, James E., Babiak, Theresa, Sheeler, Leslie, Schumacher, Peter·1989·Journal of Urology
DOI 10.1016/s0022-5347(17)40734-8
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Abstract

Between 1936 and 1987, 82 patients with adrenal cortical carcinoma were seen at our clinic. Of these patients 49 (72 per cent) have been seen during the last 25 years. A total of 40 patients (48.8 per cent) presented with a hormonally functional tumor and 42 (51.2 per cent) had a nonfunctional tumor. Forty patients (48.8 per cent) presented with localized disease, 12 (14.6 per cent) with regional disease and 30 (36.6 per cent) with distant metastases. Complete surgical removal of all gross tumor was achieved in 49 patients. Over-all 3 and 5-year patient survival rates in this series were 37.5 and 25.1 per cent, respectively. Survival was significantly improved (43.9 per cent at 5 years, p equals 0.0001) in patients with localized disease that was completely removed surgically; postoperative adjuvant therapy with op'-DDD was of no benefit in these patients. Survival in patients with metastatic disease was poor and was not improved by treatment with op'-DDD, cytotoxic chemotherapy or radiation therapy.

Overview

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Crossref · 10.1016/s0022-5347(17)40734-8

Cites

20 of 20 references verified0 citation errors · 0 not checkable

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Citations

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Research works printed but not linked: 1

  1. Brown, 1979, Adjuvant therapy, o,p′-DDD in the treatment of metastatic adrenocortical carcinoma, Clin. Res., 27, 626A

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Metadata

Authors
Bodie, B., Novick, A. C., Pontes, J. E., Straffon, R. A., Montie, J. E., Babiak, T., Sheeler, L., & Schumacher, P.
Affiliations
Cleveland Clinic (US)
ORCID
Venue
Journal of Urology
Publisher
Ovid Technologies (Wolters Kluwer Health)
Published
1989-02
Volume
141
Issue
2
Pages
257-260
ISSN
  • 0022-5347 (ISSN-L)
  • 1527-3792
DOI
10.1016/s0022-5347(17)40734-8
OpenAlex
W2415859171
Cited by
145
References
20
Citations by year
2025: 1 · 2024: 2 · 2023: 1 · 2022: 1 · 2021: 2 · 2020: 1 · 2019: 1 · 2018: 2 · 2017: 4 · 2016: 3 · 2015: 2 · 2014: 5 · 2013: 1 · 2012: 6
FWCI
3.25
Type
journal article
Language
en
Open access
closed
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations
  • The Journal of Urology (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Surgery › Adrenal and Paraganglionic Tumors
  • Health Sciences › Medicine › Oncology › Renal cell carcinoma treatment
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Adrenal Hormones and Disorders
Keywords
adrenocortical carcinoma, functional adrenal tumors, metastatic disease, surgical resection, adjuvant therapy, cytotoxic chemotherapy, radiotherapy, survival rate
MeSH terms
Actuarial Analysis, Adrenal Cortex Neoplasms, Adrenalectomy, Adult, Carcinoma, Child, Combined Modality Therapy, Female, Follow-Up Studies, Humans, Male, Mitotane, Ohio, Prognosis, Time Factors

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