The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Inhibition of Bacterial Adherence by Cranberry Juice: Potential Use For the Treatment of Urinary Tract Infections
Abstract
Cranberry juice has been widely used for the treatment and prevention of urinary tract infections and is reputed to give symptomatic relief from these infections. Attempts to account for the potential benefit derived from the juice have focused on urine acidification and bacteriostasis. In this investigation it is demonstrated that cranberry juice is a potent inhibitor of bacterial adherence. A total of 77 clinical isolates of Escherichia coli were tested. Cranberry juice inhibited adherence by 75 per cent or more in over 60 per cent of the clinical isolates. Cranberry cocktail was also given to mice in the place of their normal water supply for a period of 14 days. Urine collected from these mice inhibited adherence of E. coli to uroepithelial cells by approximately 80 per cent. Antiadherence activity could also be detected in human urine. Fifteen of 22 subjects showed significant antiadherence activity in the urine 1 to 3 hours after drinking 15 ounces of cranberry cocktail. It is concluded that the reported benefits derived from the use of cranberry juice may be related to its ability to inhibit bacterial adherence.
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Cites
Beachey, E. H. (1981) · Journal of Infectious Diseases · doi:10.1093/infdis/143.3.325 · Cited by 1,411
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Serrano, J., Puupponen‐Pimiä, R., Dauer, A., Aura, A., & Saura‐Calixto, F. (2009) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.200900039 · Cited by 810
Zafriri, D., Ofek, I., Adar, R., Pocino, M., & Sharon, N. (1989) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.33.1.92 · Cited by 417
Roopchand, D. E., Krueger, C. G., Moskal, K., Fridlender, B., Lila, M. A., & Raskin, I. (2013) · Food Chemistry · doi:10.1016/j.foodchem.2013.06.050 · Cited by 73
Metadata
- Authors
- Sobota, A. E.
- Venue
- Journal of Urology
- Published
- 1984-05
- Volume
- 131
- Issue
- 5
- Pages
- 1013-1016
- ISSN
- 0022-5347 (ISSN-L)
- 1527-3792
- OpenAlex
- W68399869
- Cited by
- 294
- References
- 1
- FWCI
- 0.00
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Inhibition of Bacterial Adherence by Cranberry Juice: Potential Use For the Treatment of Urinary Tract Infections. https://app.cochat.ai/papers/10.1016/s0022-5347(17)50751-x
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- Sobota, A. E. (1984). Inhibition of Bacterial Adherence by Cranberry Juice: Potential Use For the Treatment of Urinary Tract Infections. Journal of Urology. https://doi.org/10.1016/s0022-5347(17)50751-x
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
