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Cited by 142Prenatal Screening and DiagnosticsCongenital Anomalies and Fetal SurgeryFetal and Pediatric Neurological Disorders

Hydramnios: anomaly prevalence and sonographic detection

Dashe, J·2002·Obstetrics & Gynecology
DOI 10.1016/s0029-7844(02)02013-6
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Abstract

Objective To characterize the prevalence and ultrasound detection of fetal anomalies in pregnancies with hydramnios, and to estimate anomaly and aneuploidy risks when no sonographic abnormality is noted. Methods This was a retrospective cohort study of singleton pregnancies with hydramnios. Hydramnios was categorized as mild, moderate, or severe based on greatest amniotic fluid index of 25.0-29.9 cm, 30.0-34.9 cm, or 35.0 cm or more, respectively. Antenatal anomaly detection was compared with assessment in the immediate neonatal period. Aneuploidy and fetal deaths were analyzed separately. Results Hydramnios was diagnosed in 672 pregnancies, and 77 (11%) of neonates had one or more anomalies. Though more severe hydramnios was associated with higher likelihood of anomaly (P Conclusion The anomaly detection rate in pregnancies with hydramnios was nearly 80%, irrespective of the degree of amniotic fluid increase. Residual anomaly risk after normal sonographic evaluation was 2% or less if hydramnios was mild or moderate and 11% if severe.

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Crossref · 10.1016/s0029-7844(02)02013-6

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  • Using these definitions, mild polyhydramnios accounts for approximately 65-70% of cases, moderate polyhydramnios for 20%, and severe polyhydramnios for <15%.

    “Using these definitions, mild polyhydramnios accounts for approximately 65e70% of cases, moderate polyhydramnios for 20%, and severe polyhydramnios for <15%.3,9,14”

    From SMFM Consult Series #46: Evaluation and management of polyhydramnios (2018) · cites this paper as [9]

  • There is a risk of identification of an underlying fetal abnormality or genetic syndrome after delivery in idiopathic polyhydramnios; this risk varies with the degree of polyhydramnios.

    “There is also a risk of identification of an underlying fetal abnormality or genetic syndrome after delivery; this risk varies with the degree of polyhydramnios.5,9,16”

    From SMFM Consult Series #46: Evaluation and management of polyhydramnios (2018) · cites this paper as [9]

  • The likelihood of an underlying fetal abnormality is significantly higher with greater degrees of polyhydramnios.

    “The likelihood of an underlying fetal abnormality is significantly higher with greater degrees of polyhydramnios.3,9,14,23”

    From SMFM Consult Series #46: Evaluation and management of polyhydramnios (2018) · cites this paper as [9]

  • In one study, the residual risk that an abnormality would be detected in the immediate neonatal period ranged from 1% with mild polyhydramnios to >10% with severe polyhydramnios.

    “In one study, the residual risk that an abnormality would be detected in the immediate neonatal period ranged from 1% with mild polyhydramnios to >10% with severe polyhydramnios 9 (Table 2).”

    From SMFM Consult Series #46: Evaluation and management of polyhydramnios (2018) · cites this paper as [9]

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Authors
Dashe, J.
Affiliations
The University of Texas Southwestern Medical Center (US)
Corresponding author
Dashe, J
ORCID
Dashe, J
Venue
Obstetrics & Gynecology
Publisher
Ovid Technologies (Wolters Kluwer Health)
Published
2002-07
Volume
100
Issue
1
Pages
134-139
ISSN
0029-7844 (ISSN-L)
DOI
10.1016/s0029-7844(02)02013-6
OpenAlex
W1967963139
Cited by
142
References
1
Citations by year
2026: 2 · 2025: 5 · 2024: 8 · 2023: 8 · 2022: 5 · 2021: 7 · 2020: 5 · 2019: 7 · 2018: 7 · 2017: 14 · 2016: 6 · 2015: 10 · 2014: 6 · 2013: 13 · 2012: 4
FWCI
1.78
Type
journal article
Language
en
Open access
closed
Locations
  • Obstetrics and Gynecology (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Prenatal Screening and Diagnostics
  • Health Sciences › Medicine › Surgery › Congenital Anomalies and Fetal Surgery
  • Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Fetal and Pediatric Neurological Disorders
Keywords
polyhydramnios, fetal malformations, prenatal ultrasound diagnosis, aneuploidy, fetal death, amniotic fluid index, cardiac septal defects, cleft palate, imperforate anus, tracheoesophageal fistula
MeSH terms
Congenital Abnormalities, Adult, Analysis of Variance, Aneuploidy, Female, Fetal Death, Follow-Up Studies, Humans, Polyhydramnios, Infant, Newborn, Pregnancy, Pregnancy Outcome, Probability, Retrospective Studies, Risk Factors, Severity of Illness Index, Cohort Studies, Prevalence, Confidence Intervals, Ultrasonography, Prenatal

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