The DOI matches its Crossref record; 19 of the 19 references it cites were found in a registry or an index.
The Staging and Surgery of Musculoskeletal Neoplasms
Abstract
This review has outlined the surgical staging of benign and malignant musculoskeletal neoplasms. Based on their unique natural history, these neoplasms behave in a predictable fashion. The surgical staging system assigns progressively higher degrees of risks to the neoplasms based on their surgical grade, their anatomic location, and the presence or absence of metastases. The staging system articulates well with preoperative planning, defining the margins needed for local tumor control. Because surgery distorts most of the imaging modalities available, all clinical staging studies must be completed before surgical intervention. As more data accrue as to the importance of DNA ploidy, genetic markers, and other characteristics, it is likely they will play an important role in the diagnosis and treatment of musculoskeletal neoplasms in the future.
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“Staging is guided primarily by the Musculoskeletal Tumour Society (MSTS) staging system for sarcomas 108 , which defines tumours as being either low or high grade, confined to an anatomic compartment or violating anatomic barriers, and localized or metastatic.”
From Osteosarcoma (2022) · cites this paper as [108]
Citations
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Biology and Therapeutic Advances for Pediatric Osteosarcoma
Marina, N. M., Gebhardt, M. C., Teot, L. A., & Gorlick, R. G. (2004) · The Oncologist · doi:10.1634/theoncologist.9-4-422 · Cited by 670
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Metadata
- Authors
- Wolf, R. E., & Enneking, W. F.
- Affiliations
- University of Louisville (US)
- University of Florida Health (US)
- Corresponding author
- Enneking, William F.
- Venue
- Orthopedic Clinics of North America
- Publisher
- Elsevier BV
- Published
- 1996-07
- Volume
- 27
- Issue
- 3
- Pages
- 473-481
- ISSN
- 0030-5898 (ISSN-L)
- OpenAlex
- W2467947662
- Cited by
- 125
- References
- 19
- Citations by year
- 2026: 1 · 2025: 4 · 2024: 6 · 2023: 3 · 2022: 2 · 2021: 4 · 2020: 7 · 2019: 1 · 2018: 1 · 2017: 4 · 2016: 2 · 2015: 5 · 2014: 6 · 2013: 6 · 2012: 8
- FWCI
- 3.54
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Orthopedic Clinics of North America (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Oncology › Sarcoma Diagnosis and Treatment
- Health Sciences › Medicine › Orthopedics and Sports Medicine › Bone Tumor Diagnosis and Treatments
- Health Sciences › Medicine › Oncology › Cancer Diagnosis and Treatment
- Keywords
- musculoskeletal neoplasms, surgical staging, preoperative staging, metastasis, surgical margins, local tumor control, benign and malignant tumors, DNA ploidy, genetic markers, surgical planning
- MeSH terms
- Bone Neoplasms, Child, Extremities, Humans, Neoplasm Staging, Surgical Procedures, Operative, Muscle Neoplasms
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