Cited by 66Chemotherapy-induced cardiotoxicity and mitigationIron Metabolism and DisordersBioactive Compounds and Antitumor Agents

Oxidant-Induced Iron Signaling in Doxorubicin-Mediated Apoptosis

Kotamraju, Srigiridhar, Kalivendi, Shasi V., Konorev, Eugene, Chitambar, Christopher R., Joseph, Joy, Kalyanaraman, B.·2004·Methods in Enzymology

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Authors
Kotamraju, S., Kalivendi, S. V., Konorev, E., Chitambar, C. R., Joseph, J., & Kalyanaraman, B.
Affiliations
Medical College of Wisconsin (US)
Venue
Methods in Enzymology
Publisher
Elsevier
Published
2004
Volume
378
Pages
362-382
ISSN
0076-6879 (ISSN-L)
OpenAlex
W1580482985
Cited by
66
References
49
Citations by year
2025: 1 · 2022: 2 · 2021: 2 · 2020: 1 · 2018: 3 · 2017: 6 · 2016: 2 · 2014: 2 · 2013: 5 · 2012: 4
FWCI
24.60
Type
book chapter
Language
en
Open access
closed
Locations
  • Methods in enzymology on CD-ROM/Methods in enzymology (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • National Institutes of Health
  • National Cancer Institute (R01CA077822, CA-77822)
Topics
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Chemotherapy-induced cardiotoxicity and mitigation
  • Health Sciences › Medicine › Hematology › Iron Metabolism and Disorders
  • Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Toxicology › Bioactive Compounds and Antitumor Agents
Keywords
doxorubicin, anthracycline cardiotoxicity, oxidative stress, iron signaling, apoptosis, reactive oxygen species, transferrin receptor, iron regulatory proteins, iron-responsive element, glutathione, aconitase, hydrogen peroxide, redox activation, muscle cells, endothelial cells
MeSH terms
Aconitate Hydratase, Animals, Antibiotics, Antineoplastic, Antioxidants, Cells, Cultured, Chelating Agents, Doxorubicin, Endothelium, Heart Diseases, Humans, Iron, Iron Chelating Agents, Mitochondria, Oxidation-Reduction, Razoxane, Receptors, Transferrin, RNA, Messenger, Superoxides, Signal Transduction, Up-Regulation, Oxidants, Apoptosis, Reactive Oxygen Species, Oxidative Stress, Caspases, Response Elements, Muscle Cells, Iron-Regulatory Proteins, Iron Regulatory Protein 1, Cytochromes c

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