Oxidant-Induced Iron Signaling in Doxorubicin-Mediated Apoptosis
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There is abundant evidence that iron can cause apoptosis.
“there is abundant evidence for the ability of iron to cause apoptosis (Kotamraju et al. 2004a, b; Kurz et al. 2007, 2008b; Vanden Berghe et al. 2009)”
From Towards a unifying, systems biology understanding of large-scale cellular death and destruction caused by poorly liganded iron: Parkinson’s, Huntington’s, Alzheimer’s, prions, bactericides, chemical toxicology and others as examples (2010) · cites this paper as Kotamraju et al. 2004a, b
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Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation.
Gavrieli, Y., Sherman, Y., & Ben-Sasson, S. A. (1992) · The Journal of cell biology · doi:10.1083/jcb.119.3.493 · Cited by 9,444 · see citing works
Green, D. R., & Reed, J. C. (1998) · Science · doi:10.1126/science.281.5381.1309 · Cited by 8,998 · see citing works
Tietze, F. (1969) · Analytical Biochemistry · doi:10.1016/0003-2697(69)90064-5 · Cited by 6,077 · see citing works
LeBel, C. P., Ischiropoulos, H., & Bondy, S. C. (1992) · Chemical Research in Toxicology · doi:10.1021/tx00026a012 · Cited by 2,694 · see citing works
Sundaresan, M., Yu, Z.-X., Ferrans, V. J., Irani, K., & Finkel, T. (1995) · Science · doi:10.1126/science.270.5234.296 · Cited by 2,520 · see citing works
Doxorubicin-Induced Cardiomyopathy
Singal, P. K., & Iliskovic, N. (1998) · New England Journal of Medicine · doi:10.1056/nejm199809243391307 · Cited by 1,848 · see citing works
Bcl-2 inhibition of neural death: decreased generation of reactive oxygen species
Kane, D. J., Sarafian, T. A., Anton, R., Hahn, H., Gralla, E. B., Valentine, J. S., Örd, T., & Bredesen, D. E. (1993) · Science · doi:10.1126/science.8235659 · Cited by 1,671 · see citing works
Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosis
Sakahira, H., Enari, M., & Nagata, S. (1998) · Nature · doi:10.1038/34214 · Cited by 1,666 · see citing works
Organelle-specific initiation of cell death pathways
Ferri, K. F., & Kroemer, G. (2001) · Nature Cell Biology · doi:10.1038/ncb1101-e255 · Cited by 1,455 · see citing works
Apoptosis in Myocytes in End-Stage Heart Failure
Narula, J., Haider, N., Virmani, R., DiSalvo, T. G., Kolodgie, F. D., Hajjar, R. J., Schmidt, U., Semigran, M. J., Dec, G. W., & Khaw, B.-A. (1996) · New England Journal of Medicine · doi:10.1056/nejm199610173351603 · Cited by 1,430 · see citing works
Rothe, G., & Valet, G. (1990) · Journal of Leukocyte Biology · doi:10.1002/jlb.47.5.440 · Cited by 870 · see citing works
Detection of picomole levels of hydroperoxides using a fluorescent dichlorofluorescein assay
Cathcart, R., Schwiers, E., & Ames, B. N. (1983) · Analytical Biochemistry · doi:10.1016/0003-2697(83)90270-1 · Cited by 857 · see citing works
Intracellular Signaling by Reactive Oxygen Species during Hypoxia in Cardiomyocytes
Duranteau, J., Chandel, N. S., Kulisz, A., Shao, Z., & Schumacker, P. T. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.19.11619 · Cited by 679 · see citing works
Intracellular hydrogen peroxide and superoxide anion detection in endothelial cells
Carter, W. O., Naryanan, P. K., & Robinson, J. P. (1994) · Journal of Leukocyte Biology · doi:10.1002/jlb.55.2.253 · Cited by 636 · see citing works
Miller, F. J., Gutterman, D. D., Rios, C., Heistad, D. D., & Davidson, B. L. (1998) · Circulation Research · doi:10.1161/01.res.82.12.1298 · Cited by 623 · see citing works
Binding of apotransferrin to K562 cells: explanation of the transferrin cycle.
Klausner, R. D., Ashwell, G., van Renswoude, J., Harford, J. B., & Bridges, K. R. (1983) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.80.8.2263 · Cited by 604 · see citing works
Receptor-mediated endocytosis of transferrin in K562 cells.
Klausner, R. D., van Renswoude, J., Ashwell, G., Kempf, C., Schechter, A. N., Dean, A., & Bridges, K. R. (1983) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)32481-5 · Cited by 563 · see citing works
Generation of free radicals and lipid peroxidation by redox cycling of adriamycin and daunomycin
Goodman, J. M., & Hochstein, P. E. (1977) · Biochemical and Biophysical Research Communications · doi:10.1016/s0006-291x(77)80048-x · Cited by 545 · see citing works
Subcellular effects of adriamycin in the heart: A concise review
Singal, P. K., DEALLY, C., & Weinberg, L. E. (1987) · Journal of Molecular and Cellular Cardiology · doi:10.1016/s0022-2828(87)80392-9 · Cited by 465 · see citing works
Mitochondrial intermembrane proteins in cell death
van Gurp, M., Festjens, N., Loo, G., Saelens, X., & Vandenabeele, P. (2003) · Biochemical and Biophysical Research Communications · doi:10.1016/s0006-291x(03)00621-1 · Cited by 398 · see citing works
Kotamraju, S., Konorev, E. A., Joseph, J., & Kalyanaraman, B. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m003890200 · Cited by 372 · see citing works
Self-citationSpeyer, J. L., Green, M. D., Kramer, E. D., Rey, M. J., Sanger, J. J., Ward, C., Dubin, N., Ferrans, V. J., Stecy, P. J., Zeleniuch‐Jacquotte, A., et al. (1988) · New England Journal of Medicine · doi:10.1056/nejm198809223191203 · Cited by 356 · see citing works
Rapid responses to oxidative stress mediated by iron regulatory protein.
Pantopoulos, K., & Hentze, M. W. (1995) · The EMBO Journal · doi:10.1002/j.1460-2075.1995.tb07291.x · Cited by 328 · see citing works
Kalyanaraman, B., Perez‐Reyes, E., & Mason, R. P. (1980) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/0304-4165(80)90142-7 · Cited by 317 · see citing works
Self-citationRegulation of Cardiomyocyte Apoptotic Signaling by Insulin-like Growth Factor I
Wang, L., Ma, W., Markovich, R. P., Chen, J., & Wang, P. H. (1998) · Circulation Research · doi:10.1161/01.res.83.5.516 · Cited by 288 · see citing works
Apoptosis: biochemical aspects and clinical implications
Kiechle, F. L., & Zhang, X. (2002) · Clinica Chimica Acta · doi:10.1016/s0009-8981(02)00297-8 · Cited by 248 · see citing works
Kotamraju, S., Chitambar, C. R., Kalivendi, S. V., Joseph, J., & Kalyanaraman, B. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m111604200 · Cited by 233 · see citing works
Self-citationKalivendi, S. V., Kotamraju, S., Zhao, H., Joseph, J., & Kalyanaraman, B. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m106829200 · Cited by 225 · see citing works
Self-citationRole of iron in anthracycline cardiotoxicity: new tunes for an old song?
Minotti, G., Cairo, G., & Monti, E. (1999) · The FASEB Journal · doi:10.1096/fasebj.13.2.199 · Cited by 210 · see citing works
Daunorubicin-Induced Apoptosis in Rat Cardiac Myocytes Is Inhibited by Dexrazoxane
Sawyer, D. B., Fukazawa, R., Arstall, M. A., & Kelly, R. A. (1999) · Circulation Research · doi:10.1161/01.res.84.3.257 · Cited by 207 · see citing works
Superoxide-Driven Aconitase FE-S Center Cycling
Gardner, P. R. (1997) · Bioscience Reports · doi:10.1023/a:1027383100936 · Cited by 190 · see citing works
Campbell, K. A., Lashley, M. R., Wyatt, J. K., Nantz, M. H., & Britt, R. D. (2001) · Journal of the American Chemical Society · doi:10.1021/ja0027463 · Cited by 173 · see citing works
Apoptosis in Adriamycin Cardiomyopathy and Its Modulation by Probucol
Kumar, D., Kirshenbaum, L., Li, T.-M., Danelisen, I., & Singal, P. K. (2001) · Antioxidants and Redox Signaling · doi:10.1089/152308601750100641 · Cited by 170 · see citing works
Pantopoulos, K., Mueller, S., Atzberger, A., Ansorge, W. J., Stremmel, W., & Hentze, M. W. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.15.9802 · Cited by 163 · see citing works
Gouazé‐Andersson, V., Mirault, M.-É., Carpentier, S., Salvayre, R., Levade, T., & Andrieu‐Abadie, N. (2001) · Molecular Pharmacology · doi:10.1016/s0026-895x(24)12610-7 · Cited by 153 · see citing works
Ohashi, T., Mizutani, A., Murakami, A., Kojo, S., Ishii, T., & Taketani, S. (2001) · FEBS Letters · doi:10.1016/s0014-5793(01)03262-8 · Cited by 143 · see citing works
Induction of cyclooxygenase-2 in rat vascular smooth muscle cells in vitro and in vivo.
Pritchard, K. A., O’Banion, M. K., Miano, J. M., Vlasic, N., Bhatia, U., Young, D. A., & Stemerman, M. B. (1994) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)37223-x · Cited by 141 · see citing works
Chitambar, C. R., & Seligman, P. A. (1986) · Journal of Clinical Investigation · doi:10.1172/jci112746 · Cited by 139 · see citing works
Self-citationYen, H., Oberley, T. D., Gairola, C. G., Szweda, L. I., & Clair, D. K. S. (1999) · Archives of Biochemistry and Biophysics · doi:10.1006/abbi.1998.1011 · Cited by 138 · see citing works
Nitobe, J. (2002) · Cardiovascular Research · doi:10.1016/s0008-6363(02)00646-6 · Cited by 129 · see citing works
Konorev, E. A., Kennedy, M. C., & Kalyanaraman, B. (1999) · Archives of Biochemistry and Biophysics · doi:10.1006/abbi.1999.1337 · Cited by 119 · see citing works
Self-citationZiemann, C., Bürkle, A., Kahl, G. F., & Hirsch‐Ernst, K. I. (1999) · Carcinogenesis · doi:10.1093/carcin/20.3.407 · Cited by 117 · see citing works
Kamada, S., Kusano, H., Fujita, H., Ohtsu, M., Koya, R. C., Kuzumaki, N., & Tsujimoto, Y. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.15.8532 · Cited by 101 · see citing works
Paravicini, T. M., Gulluyan, L. M., Dusting, G. J., & Drummond, G. R. (2002) · Circulation Research · doi:10.1161/01.res.0000024106.81401.95 · Cited by 90 · see citing works
Testa, U., Pelosi, E., & Peschle, C. (1993) · PubMed · Cited by 89 · see citing works
Campbell, K. A., Yikilmaz, E., Grant, C. V., Gregor, W., Miller, A., & Britt, R. D. (1999) · Journal of the American Chemical Society · doi:10.1021/ja9902219 · Cited by 79 · see citing works
Gehring, N. H., Hentze, M. W., & Pantopoulos, K. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.10.6219 · Cited by 72 · see citing works
Mechanisms of growth inhibition by anti-transferrin receptor monoclonal antibodies.
Taetle, R., Castagnola, J., & Mendelsohn, J. M. (1986) · PubMed · Cited by 71 · see citing works
Bergeron, R. J., Wiegand, J., & Brittenham, G. M. (1999) · Blood · doi:10.1182/blood.v93.1.370 · Cited by 45 · see citing works
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Measuring reactive oxygen and nitrogen species with fluorescent probes: challenges and limitations
Kalyanaraman, B., Darley-Usmar, V. M., Davies, K. J. A., Dennery, P. A., Forman, H. J., Grisham, M. B., Mann, G. E., Moore, K. P., Roberts, L. J., & Ischiropoulos, H. (2011) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2011.09.030 · Cited by 1,795 · see citing works
Self-citationAnthracycline Cardiotoxicity: Prevalence, Pathogenesis and Treatment
Volkova, M., & Russell, R. R. (2012) · Current Cardiology Reviews · doi:10.2174/157340311799960645 · Cited by 874 · see citing works
Griendling, K. K., Touyz, R. M., Zweier, J. L., Dikalov, S., Chilian, W. M., Chen, Y., Harrison, D. G., & Bhatnagar, A. (2016) · Circulation Research · doi:10.1161/res.0000000000000110 · Cited by 452 · see citing works
Kell, D. B. (2010) · Archives of Toxicology · doi:10.1007/s00204-010-0577-x · Cited by 361 · see citing works
New insights into doxorubicin-induced cardiotoxicity: The critical role of cellular energetics
Tokarska-Schlattner, M., Zaugg, M., Zuppinger, C., Wallimann, T., & Schlattner, U. (2006) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2006.06.009 · Cited by 353 · see citing works
New insights and evolving role of pegylated liposomal doxorubicin in cancer therapy
Gabizón, A., Patil, Y. P., & La-Beck, N. M. (2016) · Drug Resistance Updates · doi:10.1016/j.drup.2016.10.003 · Cited by 251 · see citing works
Fucoxanthin induces apoptosis in human leukemia HL-60 cells through a ROS-mediated Bcl-xL pathway
Kim, K., Heo, S., Kang, S., Ahn, G., & Jeon, Y. (2010) · Toxicology in Vitro · doi:10.1016/j.tiv.2010.05.023 · Cited by 213 · see citing works
Doxorubicin-induced ovarian toxicity
Ben‐Aharon, I., Bar‐Joseph, H., Tzarfaty, G., Kuchinsky, L., Rizel, S., Stemmer, S. M., & Shalgi, R. (2010) · Reproductive Biology and Endocrinology · doi:10.1186/1477-7827-8-20 · Cited by 172 · see citing works
Emerging delivery systems to reduce doxorubicin cardiotoxicity and improve therapeutic index
Tahover, E., Patil, Y. P., & Gabizón, A. (2014) · Anti-Cancer Drugs · doi:10.1097/cad.0000000000000182 · Cited by 160 · see citing works
Filomeni, G., Cerchiaro, G., Ferreira, A. M. D. C., Martino, A. D., Pedersen, J. Z., Rotilio, G., & Ciriolo, M. R. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m610927200 · Cited by 151 · see citing works
Minotti, G., Recalcati, S., Menna, P., Salvatorelli, E., Corna, G., & Cairo, G. (2004) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/s0076-6879(04)78025-8 · Cited by 135 · see citing works
Jones, R. L., Swanton, C., & Ewer, M. S. (2006) · Expert Opinion on Drug Safety · doi:10.1517/14740338.5.6.791 · Cited by 127 · see citing works
Kalyanaraman, B. (2022) · Redox Biology · doi:10.1016/j.redox.2022.102497 · Cited by 118 · see citing works
Self-citationEarly Detection of Doxorubicin Cardiomyopathy Using Two-Dimensional Strain Echocardiography
Migrino, R. Q., Aggarwal, D., Konorev, E. A., Brahmbhatt, T., Bright, M., & Kalyanaraman, B. (2007) · Ultrasound in Medicine & Biology · doi:10.1016/j.ultrasmedbio.2007.07.018 · Cited by 118 · see citing works
Self-citationNew Developments in Anthracycline-Induced Cardiotoxicity
Mordente, A., Meucci, E., Silvestrini, A., Martorana, G. E., & Giardina, B. (2009) · Current Medicinal Chemistry · doi:10.2174/092986709788186228 · Cited by 112 · see citing works
Cheng, G., Zielonka, M., Dranka, B. P., Kumar, S. N., Myers, C. R., Bennett, B., Garces, A. M., Machado, L. G. D. D., Thiébaut, D., Ouari, O., et al. (2018) · Journal of Biological Chemistry · doi:10.1074/jbc.ra118.003044 · Cited by 111 · see citing works
Self-citationDetection of cellular redox reactions and antioxidant activity assays
Meng, D., Zhang, P., Zhang, L., Wang, H., Ho, C., Li, S., Shahidi, F., & Zhao, H. (2017) · Journal of Functional Foods · doi:10.1016/j.jff.2017.08.008 · Cited by 95 · see citing works
Defective One- or Two-electron Reduction of the Anticancer Anthracycline Epirubicin in Human Heart
Salvatorelli, E., Guarnieri, S., Menna, P., Liberi, G., Calafiore, A. M., Mariggiò, M. A., Mordente, A., Gianni, L., & Minotti, G. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m508343200 · Cited by 93 · see citing works
Whitsett, J., Picklo, M. J., & Vasquez-Vivar, J. M. (2007) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.107.153742 · Cited by 92 · see citing works
Lee, W., Cheung, C. C. M., Liu, K. W. K., Fung, K., Wong, J., Lai, P. B. S., & Yeung, J. H. K. (2010) · Journal of Natural Products · doi:10.1021/np900792p · Cited by 83 · see citing works
Venkatakrishnan, C. D., Tewari, A. K., Moldovan, L., Cardounel, A. J., Zweier, J. L., Kuppusamy, P., & Ilangovan, G. (2006) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00395.2006 · Cited by 80 · see citing works
RetractedROS-driven Akt dephosphorylation at Ser-473 is involved in 4-HPR-mediated apoptosis in NB4 cells
Cao, J., Xu, D., Wang, D., Wu, R., Zhang, L., Zhu, H., He, Q., & Yang, B. (2009) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2009.05.024 · Cited by 78 · see citing works
Lu, H., Zhu, H., Huang, M., Chen, Y., Cai, Y.-J., Miao, Z., Zhang, J., & Ding, J. (2005) · Molecular Pharmacology · doi:10.1124/mol.105.011544 · Cited by 77 · see citing works
Kalyanaraman, B. (2011) · Biochemical Society Transactions · doi:10.1042/bst0391221 · Cited by 74 · see citing works
Self-citationCong, W., Ling, J., Tian, H., Ling, R., Wang, Y., Huang, B., Zhao, T., Duan, Y., Jin, L., & Li, X. K. (2013) · Canadian Journal of Physiology and Pharmacology · doi:10.1139/cjpp-2012-0441 · Cited by 71 · see citing works
Turakhia, S., Venkatakrishnan, C. D., Dunsmore, K., Wong, H. R., Kuppusamy, P., Zweier, J. L., & Ilangovan, G. (2007) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00328.2007 · Cited by 69 · see citing works
Volkova, M., Palmeri, M., Russell, K. S., & Russell, R. R. (2011) · Cardiovascular Research · doi:10.1093/cvr/cvr007 · Cited by 63 · see citing works
Popelová, O., Štěrba, M., Hašková, P., Šimůnek, T., Hroch, M., Gunčová, I., Nachtigal, P., Adamcová, M., Geršl, V., & Mazurová, Y. (2009) · British Journal of Cancer · doi:10.1038/sj.bjc.6605192 · Cited by 61 · see citing works
Redox proteomic identification of oxidized cardiac proteins in Adriamycin-treated mice
Chen, Y., Daosukho, C., Opii, W. O., Turner, D. M., Pierce, W. M. J., Klein, J. B., Vore, M. E., Butterfield, D. A., & Clair, D. K. S. (2006) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2006.08.006 · Cited by 60 · see citing works
Cai, Y.-J., Lu, J., Zhu, H., Xie, H., Huang, M., Lin, L., Zhang, X., & Ding, J. (2008) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2008.05.017 · Cited by 54 · see citing works
Jing, Y., Yang, J., Wang, Y., Li, H., Chen, Y., Hu, Q.-S., Shi, G., Tang, X., & Yi, J. (2006) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2006.02.016 · Cited by 51 · see citing works
Wang, N., Eckert, K. A., Zomorrodi, A. R., Xin, P., Pan, W., Shearer, D. A., Weisz, J., Maranus, C. D., & Clawson, G. A. (2012) · PLoS ONE · doi:10.1371/journal.pone.0039446 · Cited by 48 · see citing works
Lin, S., Chou, H., Chang, S., Chen, Y., Lyu, P. C., Wang, W., Chang, M. D., & Chan, H. (2012) · Journal of Proteomics · doi:10.1016/j.jprot.2012.07.047 · Cited by 46 · see citing works
Walker, D. M., Fisher, B. T., Seif, A. E., Huang, Y.-S. V., Torp, K., Li, Y., & Aplenc, R. (2012) · Pediatric Blood & Cancer · doi:10.1002/pbc.24270 · Cited by 45 · see citing works
Oxidative stress in NSC-741909-induced apoptosis of cancer cells
Wei, X., Guo, W., Wu, S., Wang, L., Huang, P., Liu, J., & Fang, B. (2010) · Journal of Translational Medicine · doi:10.1186/1479-5876-8-37 · Cited by 43 · see citing works
Chen, H.-M., Chang, F., Hsieh, Y.-C., Cheng, Y.-J., Hsieh, K., Tsai, L.-M., Lin, A., Wu, Y., & Yuan, S. F. (2011) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2011.01.015 · Cited by 40 · see citing works
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Goncharov, I., Weiner, L. M., & Vogel, Z. (2005) · Neuroscience · doi:10.1016/j.neuroscience.2005.04.042 · Cited by 36 · see citing works
Nishi, K., Gunasekaran, V. P., Arunachalam, J., & Ganeshan, M. (2017) · Drug and Chemical Toxicology · doi:10.1080/01480545.2017.1307851 · Cited by 34 · see citing works
Zinc inhibits oxidative stress-induced iron signaling and apoptosis in Caco-2 cells
Kilari, S., Pullakhandam, R., & Nair, K. M. (2010) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2010.01.019 · Cited by 32 · see citing works
MEX is a testis-specific E3 ubiquitin ligase that promotes death receptor-induced apoptosis
Nishito, Y., Hasegawa, M., Inohara, N., & Núñez, G. (2006) · Biochemical Journal · doi:10.1042/bj20051814 · Cited by 30 · see citing works
Seol, Y.-B., Kim, J., Park, S.-H., & Chang, H. Y. (2017) · Scientific Reports · doi:10.1038/s41598-017-00480-6 · Cited by 30 · see citing works
Abdelmohsen, K., von Montfort, C., Stuhlmann, D., Gerber, P. A., Decking, U. K. M., Sies, H., & Klotz, L. (2005) · Biological Chemistry · doi:10.1515/bc.2005.027 · Cited by 27 · see citing works
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Eckman, D. M., Stacey, R. B., Rowe, R., D′Agostino, R., Kock, N. D., Sane, D. C., Torti, F. M., Yeboah, J., Workman, S., Lane, K. S., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0057554 · Cited by 25 · see citing works
Lehnhardt, M., Klein‐Hitpaß, L., Kuhnen, C., Homann, H. H., Daigeler, A., Steinau, H. U., Röhrs, S., Schnoor, L., Steinstraesser, L., & Müller, O. (2005) · BMC Cancer · doi:10.1186/1471-2407-5-74 · Cited by 24 · see citing works
Sudheesh, N. P., Ajith, T. A., & Janardhanan, K. K. (2013) · Toxicology Mechanisms and Methods · doi:10.3109/15376516.2013.769289 · Cited by 23 · see citing works
He, P., Zhang, J., Che, Y., He, Q., Chen, Y., & Ding, J. (2014) · Acta Pharmacologica Sinica · doi:10.1038/aps.2014.105 · Cited by 19 · see citing works
Zhou, Y., Gu, X., Ashayeri, E., Zhang, R., & Sridhar, R. (2007) · PubMed Central · Cited by 13 · see citing works
Wu, Z., Yu, J., Fang, Q., Lian, J., Wang, R.-X., He, R., & Lin, M. (2013) · Journal of Cardiovascular Pharmacology · doi:10.1097/fjc.0000000000000056 · Cited by 9 · see citing works
Feitosa, L. A. D. S., Carvalho, J. S., Dantas, C. O., Souza, D. S., de Vasconcelos, C. M. L., Miguel‐dos‐Santos, R., Lauton‐Santos, S., Quintans‐Júnior, L. J., dos Santos, M. R. V., Santana‐Filho, V. J., et al. (2021) · Cardiovascular Toxicology · doi:10.1007/s12012-020-09627-w · Cited by 9 · see citing works
Formation of Reactive Oxygen Species in Mitochondria
Turrens, J. F. (2007) · Springer eBooks · doi:10.1007/978-0-387-69945-5_8 · Cited by 9 · see citing works
MiR-199 Aggravates Doxorubicin-Induced Cardiotoxicity by Targeting TAF9b
Yu, Y., Guo, D., & Zhao, L. (2022) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2022/4364779 · Cited by 6 · see citing works
RetractedАрманович, А. А., Gvianishvili, T., Gogiashvili, L., Kakturskiy, L., Sarrafzadegan, N., & Aznauryan, A. (2021) · Current Problems in Cardiology · doi:10.1016/j.cpcardiol.2021.101051 · Cited by 9 · see citing works
Cytomics of Oxidative Stress: Probes and Problems
O’Connor, J., Herrera, G., de Oyanguren, F. S., Jávega, B., & Martínez‐Romero, A. (2017) · Series in bioengineering · doi:10.1007/978-981-10-4499-1_4 · Cited by 4 · see citing works
Cardiac wasting in patients with advanced cancer: state of the art review
Khan, L. A., Khan, M. S., Latif, R. U., & Anker, M. S. (2025) · Global Cardiology · doi:10.4081/cardio.2025.65 · Cited by 3 · see citing works
Filip, S., Kubeček, O., Špaček, J., Lánská, M., & Blaha, M. (2020) · Pharmaceutics · doi:10.3390/pharmaceutics12100940 · Cited by 3 · see citing works
Cardiovascular Complications of Chemotherapy: Anthracycline Cardiotoxicity
Russell, R. R. (2013) · Springer eBooks · doi:10.1007/978-1-4471-4441-0_26 · Cited by 2 · see citing works
MacCallum, N. S., Quinlan, G. J., & Evans, T. W. (2006) · Springer eBooks · doi:10.1007/3-540-30328-6_25 · Cited by 1 · see citing works
Recherche bioguidée de molécules anticancéreuses issues de microalgues marines
Pasquet, V. (2011) · doi:10.70675/0fa9f584z5c31z4314z887cza263fc876be0 · Cited by 1 · see citing works
Researchstress in NSC-741909-induced apoptosis of cancer cells
Wei, X., Guo, W., Wu, S., Wang, L., Huang, P., Liu, J., & Fang, B. (2010)
Chen, Y., Daosukho, C., Opii, W. O., Turner, D. M., Pierce, W. M. J., Klein, J. B., Vore, M. E., Butterfield, D. A., & St, D. K. (2006)
Fayyaz, T. B., Memon, Z., Baig, M. T., Ain, N. U., & Aziz, M. S. (2017) · The Professional Medical Journal · doi:10.17957/tpmj/17.3755
Cardio-oncology: Understanding cardiotoxicity to guide patient focused imaging
Russell, R. R. (2018) · Journal of Nuclear Cardiology · doi:10.1007/s12350-018-01470-5
Faculty Opinions recommendation of Doxorubicin-induced ovarian toxicity.
Selvanesan, B. C. (2010) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.2838956.2504054
Fayyaz, T. B., Memon, Z., Baig, M. T., Ain, N. U., & Aziz, M. S. (2017) · The Professional Medical Journal · doi:10.29309/tpmj/2017.24.05.1296
- Authors
- Kotamraju, S., Kalivendi, S. V., Konorev, E., Chitambar, C. R., Joseph, J., & Kalyanaraman, B.
- Affiliations
- Medical College of Wisconsin (US)
- Venue
- Methods in Enzymology
- Publisher
- Elsevier
- Published
- 2004
- Volume
- 378
- Pages
- 362-382
- ISSN
- 0076-6879 (ISSN-L)
- OpenAlex
- W1580482985
- Cited by
- 66
- References
- 49
- Citations by year
- 2025: 1 · 2022: 2 · 2021: 2 · 2020: 1 · 2018: 3 · 2017: 6 · 2016: 2 · 2014: 2 · 2013: 5 · 2012: 4
- FWCI
- 24.60
- Type
- book chapter
- Language
- en
- Open access
- closed
- Locations
- Methods in enzymology on CD-ROM/Methods in enzymology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health
- National Cancer Institute (R01CA077822, CA-77822)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Chemotherapy-induced cardiotoxicity and mitigation
- Health Sciences › Medicine › Hematology › Iron Metabolism and Disorders
- Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Toxicology › Bioactive Compounds and Antitumor Agents
- Keywords
- doxorubicin, anthracycline cardiotoxicity, oxidative stress, iron signaling, apoptosis, reactive oxygen species, transferrin receptor, iron regulatory proteins, iron-responsive element, glutathione, aconitase, hydrogen peroxide, redox activation, muscle cells, endothelial cells
- MeSH terms
- Aconitate Hydratase, Animals, Antibiotics, Antineoplastic, Antioxidants, Cells, Cultured, Chelating Agents, Doxorubicin, Endothelium, Heart Diseases, Humans, Iron, Iron Chelating Agents, Mitochondria, Oxidation-Reduction, Razoxane, Receptors, Transferrin, RNA, Messenger, Superoxides, Signal Transduction, Up-Regulation, Oxidants, Apoptosis, Reactive Oxygen Species, Oxidative Stress, Caspases, Response Elements, Muscle Cells, Iron-Regulatory Proteins, Iron Regulatory Protein 1, Cytochromes c
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