Chapter 12: Signaling by extracellular ATP: physiological and pathological considerations in neuronal-astrocytic interactions

Extracellular ATP: effects, sources and fate

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The physiological activity of adenine compounds with especial reference to their action upon the mammalian heart1

Drury, A. N., & Szent-Györgyi, A. (1929) · The Journal of Physiology · doi:10.1113/jphysiol.1929.sp002608 · Cited by 1,487

PROTEIN SERINE/THREONINE KINASES

Edelman, A. M., Blumenthal, D. K., & Krebs, E. G. (1987) · Annual Review of Biochemistry · doi:10.1146/annurev.bi.56.070187.003031 · Cited by 1,433

A novel receptor-operated Ca2+-permeable channel activated by ATP in smooth muscle

Benham, C. D., & Tsien, R. W. (1987) · Nature · doi:10.1038/328275a0 · Cited by 781

A basis for distinguishing two types of purinergic receptor

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The liberation of adenosine triphosphate on antidromic stimulation of sensory nerves

Holton, P. (1959) · The Journal of Physiology · doi:10.1113/jphysiol.1959.sp006157 · Cited by 499

Overview: Purinergic Mechanisms

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A Spatial-Temporal Model of Cell Activation

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On the association between transmitter secretion and the release of adenine nucleotides from mammalian motor nerve terminals.

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Regulation of neuronal function by calcium

Kennedy, M. B. (1989) · Trends in Neurosciences · doi:10.1016/0166-2236(89)90089-1 · Cited by 306

Purinergic Signalling: Pathophysiological Roles

Maria P., A., & Geoffrey, B. (1998) · Japanese Journal of Pharmacology · doi:10.1254/jjp.78.113 · Cited by 444

Trophic actions of extracellular nucleotides and nucleosides on glial and neuronal cells

Neary, J. T., Rathbone, M. P., Cattabeni, F., Abbracchio, M. P., & Burnstock, G. (1996) · Trends in Neurosciences · doi:10.1016/0166-2236(96)81861-3 · Cited by 444

Physiological and pathophysiological functions of the ecto-nucleotide pyrophosphatase/phosphodiesterase family

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Involvement of astrocytes in purine‐mediated reparative processes in the brain

Ciccarelli, R., Ballerini, P., Sabatino, G., Rathbone, M. P., D’Onofrio, M., Caciagli, F., & Iorio, P. D. (2001) · International Journal of Developmental Neuroscience · doi:10.1016/s0736-5748(00)00084-8 · Cited by 242

Activation of Extracellular Signal-Regulated Kinase by Stretch-Induced Injury in Astrocytes Involves Extracellular ATP and P2 Purinergic Receptors

Neary, J. T., Kang, Y., Willoughby, K. A., & Ellis, E. F. (2003) · Journal of Neuroscience · doi:10.1523/jneurosci.23-06-02348.2003 · Cited by 238

Pathophysiology of astroglial purinergic signalling

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Purinoceptors in the Nervous System*

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P2X receptor expression on astrocytes in the nucleus accumbens of rats

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Modulation of astroglial cell proliferation by analogues of adenosine and ATP in primary cultures of rat striatum

Abbracchio, M. P., Saffrey, M. J., Höpker, V. H., & Burnstock, G. (1994) · Neuroscience · doi:10.1016/0306-4522(94)90099-x · Cited by 142

P2 Purinoceptors: Historical Perspective and Classification

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P2 receptor-mediated proliferative effects on astrocytes in vivo

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An Ecto‐Nucleotide Pyrophosphatase Is One of the Main Enzymes Involved in the Extracellular Metabolism of ATP in Rat C6 Glioma

Grobben, B., Anciaux, K., Roymans, D., Stefan, C., Bollen, M., Esmans, E. L., & Slegers, H. (1999) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1999.0720826.x · Cited by 104

P2 purinoceptors in rat cortical astrocytes: Expression, calcium-imaging and signalling studies

King, B. F., Neary, J. T., Zhu, Q., Wang, S., Norenberg, M. D., & Burnstock, G. (1996) · Neuroscience · doi:10.1016/0306-4522(96)00209-6 · Cited by 99

P2 receptor‐types involved in astrogliosis in vivo

Franke, H., Krügel, U., Schmidt, R., Grosche, J., Reichenbach, A., & Illés, P. (2001) · British Journal of Pharmacology · doi:10.1038/sj.bjp.0704353 · Cited by 98

P2Y receptor expression on astrocytes in the nucleus accumbens of rats

Franke, H., Krügel, U., Grosche, J., Heine, C., Härtig, W., Allgaier, C., & Illés, P. (2004) · Neuroscience · doi:10.1016/j.neuroscience.2004.05.003 · Cited by 93

Dr. Jekyll/Mr. Hyde: the dual role of extracellular ATP

Virgilio, F. D. (2000) · Journal of the Autonomic Nervous System · doi:10.1016/s0165-1838(00)00114-4 · Cited by 89

Traumatic Injury Activates Protein Kinase B/Akt in Cultured Astrocytes: Role of Extracellular ATP and P2 Purinergic Receptors

Neary, J. T., Kang, Y., Tran, M., & Feld, J. (2005) · Journal of Neurotrauma · doi:10.1089/neu.2005.22.491 · Cited by 88

Effects of exogenous ATP and related analogues on the proliferation rate of dissociated primary cultures of rat astrocytes

Ciccarelli, R., Iorio, P. D., Ballerini, P., Ambrosini, G., Giuliani, P., Tiboni, G. M., & Caciagli, F. (1994) · Journal of Neuroscience Research · doi:10.1002/jnr.490390507 · Cited by 88

Nucleotides as Extracellular Signalling Molecules

Chen, Z., Levy, A., & Lightman, S. L. (1995) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.1995.tb00671.x · Cited by 86

Activation of P2X7 receptors induced [3H]GABA release from the RBA‐2 type‐2 astrocyte cell line through a Cl−/HCO3−‐dependent mechanism

Wang, C., Chang, Y., Kuo, J., & Sun, S. H. (2001) · Glia · doi:10.1002/glia.10004 · Cited by 82

Extracellular ATP‐induced currents in astrocytes: Involvement of a cation channel

Walz, W., Gimpl, G., Ohlemeyer, C., & Kettenmann, H. (1994) · Journal of Neuroscience Research · doi:10.1002/jnr.490380104 · Cited by 79

Extrinsic Purinergic Regulation of Neural Stem/Progenitor Cells: Implications for CNS Development and Repair

Ulrich, H., Abbracchio, M. P., & Burnstock, G. (2012) · Stem Cell Reviews and Reports · doi:10.1007/s12015-012-9372-9 · Cited by 73

Extracellular guanosine and guanosine-5′-triphosphate increase: NGF synthesis and release from cultured mouse neopallial astrocytes

Middlemiss, P. J., Gysbers, J. W., & Rathbone, M. P. (1995) · Brain Research · doi:10.1016/0006-8993(95)00156-k · Cited by 62

ATP stimulates release of excitatory amino acids from cultured Schwann cells

Jeftinija, S., & Jeftinija, K. (1997) · Neuroscience · doi:10.1016/s0306-4522(97)00310-2 · Cited by 61

Agonist‐Induced Internalization and Recycling of the Human A3Adenosine Receptors: Role in Receptor Desensitization and Resensitization

Trincavelli, M. L., Tuscano, D., Cecchetti, P., Falleni, A., Benzi, L., Klotz, K., Gremigni, V., Cattabeni, F., Lucacchini, A., & Martini, C. (2000) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2000.0751493.x · Cited by 60

P1 and P2 receptors in cell growth and differentiation

Abbracchio, M. P. (1996) · Drug Development Research · Cited by 58

Effects of ATP analogues and basic fibroblast growth factor on astroglial cell differentiation in primary cultures of rat striatum

Abbracchio, M. P., Ceruti, S., Langfelder, R. M. B., Cattabeni, F., Saffrey, M. J., & Burnstock, G. (1995) · International Journal of Developmental Neuroscience · doi:10.1016/0736-5748(95)00064-x · Cited by 58

Mechanisms of intracellular calcium regulation in adult astrocytes

Peuchen, S., Clark, J. B., & Duchen, M. R. (1996) · Neuroscience · doi:10.1016/0306-4522(95)00515-3 · Cited by 51

P2 purinoceptor localization along rat nephron and evidence suggesting existence of subtypes P2Y1and P2Y2

Ho, S., Sekine, T., & Endou, H. (1998) · American Journal of Physiology-Renal Physiology · doi:10.1152/ajprenal.1998.274.6.f1006 · Cited by 47

Adenosine triphosphate and arachidonic acid stimulate glycogenolysis in primary cultures of mouse cerebral cortical astrocytes

Sorg, O., Pellerin, L., Stolz, M., Beggah, S., & Magistretti, P. J. (1995) · Neuroscience Letters · doi:10.1016/0304-3940(95)11410-x · Cited by 46

Trophic Actions of Extracellular ATP on Astrocytes, Synergistic Interactions with Fibroblast Growth Factors and Underlying Signal Transduction Mechanisms

Neary, J. T. (2007) · Novartis Foundation symposium · doi:10.1002/9780470514900.ch7 · Cited by 44

ATP acting on P 2Y receptors triggers calcium mobilization in primary cultures of rat neurohypophysial astrocytes (pituicytes)

Troadec, J., Thirion, S., Petturiti, D., Bohn, M., & Poujeol, P. (1999) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s004240050841 · Cited by 42

Regional distribution of [35S]2′-deoxy 5′-O-(1-thio) ATP binding sites and the P2Y1 messenger RNA within the chick brain

Webb, T. E., Simon, J., & Barnard, E. A. (1998) · Neuroscience · doi:10.1016/s0306-4522(97)00478-8 · Cited by 42

Chapter 27 Signalling mechanisms involved in P2Y receptor-mediated reactive astrogliosis

Abbracchio, M. P., Brambilla, R., Ceruti, S., & Cattabeni, F. (1999) · Progress in brain research · doi:10.1016/s0079-6123(08)63567-0 · Cited by 37

Agonists of the P2YAC‐receptor activate MAP kinase by a ras‐independent pathway in rat C6 glioma

Grobben, B., Claes, P., Kolen, K. V., Roymans, D., Fransen, P. F., Sys, S. U., & Slegers, H. (2001) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2001.00524.x · Cited by 31

Trophic Roles of P2 Purinoceptors in Central Nervous System Astroglial Cells

Abbracchio, M. P., Ceruti, S., Bolego, C., Puglisi, L., Burnstock, G., & Cattabeni, F. (2007) · Novartis Foundation symposium · doi:10.1002/9780470514900.ch8 · Cited by 31

Potential Role of Purinergic Signalling in Cochlear Pathology

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ATP receptors

Edwards, F. A. (1994) · Current Opinion in Neurobiology · doi:10.1016/0959-4388(94)90095-7 · Cited by 28

Trophic Roles of Purines and Pyrimidines

Neary, J. T., & Abbracchio, M. P. (2001) · Springer eBooks · doi:10.1007/978-3-662-09604-8_11 · Cited by 25

Challenges in Developing P2 Purinoceptor‐Based Therapeutics

Williams, M. J. (2007) · Novartis Foundation symposium · doi:10.1002/9780470514900.ch18 · Cited by 18

The Diverse Series of Recombinant P2Y Purinoceptors

Barnard, E. A., Webb, T. E., Simon, J., & Kunapuli, S. P. (2007) · Novartis Foundation symposium · doi:10.1002/9780470514900.ch10 · Cited by 17

Pathological Potential of Astroglial Purinergic Receptors

Franke, H., & Illés, P. (2014) · Advances in neurobiology · doi:10.1007/978-3-319-08894-5_11 · Cited by 16

Effects of ATP and derivatives on neuropile glial cells of the leech central nervous system

M�ller, M., Henrich, A., Klockenhoff, J., Dierkes, P. W., & Schlue, W. R. (2000) · Glia · doi:10.1002/(sici)1098-1136(20000201)29:3<191::aid-glia1>3.0.co;2-r · Cited by 16

P2 receptors on macroglial cells: Functional implications for gliosis

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ECTO-Atpases of the Nervous System

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Mining the effect of the neonicotinoids imidacloprid and clothianidin on the chemical homeostasis and energy equilibrium of primary mouse neural stem/progenitor cells using metabolomics

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Purinoceptors on Glial Cells of the Central Nervous System: Functional and Pathologic Implications

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Immunoreactivity for glial fibrillary acidic protein and P2 receptor expression on astrocytes in vivo

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Section Review Central & Peripheral Nervous Systems: P2-Purinoceptors: Advances and therapeutic opportunities

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Astrocyte-specific inhibition of the primary cilium suppresses C3 expression in reactive astrocyte

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Role of mitogen‐activated protein kinase cascades in P2Y receptor‐mediated trophic activation of astroglial cells

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Cyclic AMP and Tyrosine Kinase Cascades in the Regulation of Cellular Function by P2Y Nucleotide Receptors

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Identification of a novel P2 receptor associated with cyclooxygenase‐2 upregulation and reactive astrogliosis

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Mechanisms of Astrocytic Calcium Wave Propagation and In Vitro Hippocampal Cell Death Are Determined By The Magnitude Of Mechanical Injury

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Molecular structure of G protein-coupled P2 purinoceptors

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Research Overview Identification of a Novel P2 Receptor Associated With Cyclooxygenase-2 Upregulation and Reactive Astrogliosis

Brambilla, R., Schiller, P. C., Neary, J. T., Burnstock, G., Cattabeni, F., & Abbracchio, M. P. (2001)

Untitled work

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ATP‐Evoked Calcium Flux, Protein Phosphorylation, and Stellation in Astrocytes

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ATP-evoked calcium signal stimulates protein phosphorylation/dephosphorylation in astrocytes

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P2X and P2Y purinoreceptors mediate ATP-evoked calcium signalling in optic nerve glia in situ

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ATP stimulates calcium influx in primary astrocyte cultures

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P2 purinoceptors in rat cortical astrocytes: Expression, calcium-imaging and signalling studies

King, B. F., Neary, J. T., Zhu, Q., Wang, S., Norenberg, M. D., & Burnstock, G. (1996) · Neuroscience · doi:10.1016/0306-4522(96)00209-6 · Cited by 99