Nuclear Receptors in Sicily: All in the Famiglia
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For the androgenic influence, co-factors such as members of the nuclear receptor family are required.
“Studies revealed that for the androgenic influence co-factors are also required, like members of the nuclear receptor family, which by directly binding to specific DNA sequences can regulate the expression of their target genes upon activation with their ligands.70”
From Sebaceous-immunobiology is orchestrated by sebum lipids (2017) · cites this paper as [70]
In “Chromatin-Protecting Armor” (page not specified in our copy), the paper describes nuclear receptors as sequence-specific DNA-binding proteins that turn hormonal signals into transcriptional responses. It discusses nuclear-receptor cofactors as possible mediators of regulation, but does not establish that cofactors are required for androgenic effects or describe nuclear receptors themselves as cofactors. (LLM, conf=0.86)
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Sebaceous-immunobiology is orchestrated by sebum lipids
Lovászi, M., Szegedi, A., Zouboulis, C. C., & Törőcsik, D. (2017) · Dermato-Endocrinology · doi:10.1080/19381980.2017.1375636 · Cited by 151 · see citing works
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- Authors
- Perlmann, T., & Evans, R. M.
- Affiliations
- Ludwig Cancer Research (SE)
- Salk Institute for Biological Studies (US)
- Corresponding author
- Evans, Ronald M
- Venue
- Cell
- Publisher
- Elsevier BV
- Published
- 1997-08
- Volume
- 90
- Issue
- 3
- Pages
- 391-397
- ISSN
- 0092-8674 (ISSN-L)
- OpenAlex
- W2039175485
- Cited by
- 148
- References
- 0
- Citations by year
- 2023: 1 · 2021: 1 · 2020: 1 · 2017: 2 · 2016: 1 · 2014: 2
- FWCI
- 14.49
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Cell (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Estrogen and related hormone effects
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Nuclear Receptors and Signaling
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Peroxisome Proliferator-Activated Receptors
- Keywords
- nuclear receptors, nuclear receptor structure, nuclear receptor function, Erice
- MeSH terms
- Animals, Chromatin, Histones, Humans, Models, Biological, Receptors, Estrogen, Receptors, Thyroid Hormone, Signal Transduction, Receptors, Cytoplasmic and Nuclear, Receptors, Retinoic Acid
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