The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Re-emergence of fatal human influenza A subtype H5N1 disease
Open accessAbstract
Human disease associated with influenza A subtype H5N1 re-emerged in January, 2003, for the first time since an outbreak in Hong Kong in 1997. Patients with H5N1 disease had unusually high serum concentrations of chemokines (eg, interferon induced protein-10 [IP-10] and monokine induced by interferon gamma [MIG]). Taken together with a previous report that H5N1 influenza viruses induce large amounts of proinflammatory cytokines from macrophage cultures in vitro, our findings suggest that cytokine dysfunction contributes to the pathogenesis of H5N1 disease. Development of vaccines against influenza A (H5N1) virus should be made a priority.
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“The rapid and intense nature of the host inflammatory response is the suspected cause of severe lung damage (116).”
From Into the Eye of the Cytokine Storm (2012) · cites this paper as [116]
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“The paradigm of “hit hard and hit early” popularized for the treatment of AIDS also appears to apply to the way H5N1 avian influenza virus causes tissue damage in human infections.”
From Into the Eye of the Cytokine Storm (2012) · cites this paper as [116]
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Human influenza A H5N1 virus related to a highly pathogenic avian influenza virus
Claas, E. C. J., Osterhaus, A. D. M. E., van Beek, R., de Jong, J. C., Rimmelzwaan, G. F., Senne, D. A., Krauss, S. L., Shortridge, K. F., & Webster, R. G. (1998) · The Lancet · doi:10.1016/s0140-6736(97)11212-0 · Cited by 1,420
Yuen, K., Chan, P., Peiris, M. J. S., Tsang, D., Que, T., Shortridge, K. F., Cheung, P., To, W., Ho, E., Sung, R. Y. T., et al. (1998) · The Lancet · doi:10.1016/s0140-6736(98)01182-9 · Cited by 1,054
Self-citationCheung, C., Poon, L., Lau, A., Luk, W., Lau, Y., Shortridge, K., Gordon, S., Guan, Y., & Peiris, J. (2002) · The Lancet · doi:10.1016/s0140-6736(02)11772-7 · Cited by 889
Self-citationKoopmans, M., Wilbrink, B., Conyn, M., Natrop, G., van der Nat, H., Vennema, H., Meijer, A., van Steenbergen, J., Fouchier, R. A. M., Osterhaus, A. D. M. E., et al. (2004) · The Lancet · doi:10.1016/s0140-6736(04)15589-x · Cited by 829
Targets of a protease inhibitor, KNI-272, in HIV-1-infected cells
Goto, T., Nakano, T., Kohno, T., Morimatsu, S., Morita, C., Wu, H. Y., Kiso, Y., Nakai, M., & Sano, K. (2001) · Journal of Medical Virology · doi:10.1002/1096-9071(200103)63:3 · Cited by 5
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Into the Eye of the Cytokine Storm
Tisoncik, J. R., Korth, M. J., Simmons, C. P., Farrar, J., Martin, T. R., & Katze, M. G. (2012) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.05015-11 · Cited by 1,940
Fatal outcome of human influenza A (H5N1) is associated with high viral load and hypercytokinemia.
de Jong, M. D., Simmons, C. P., Thanh, T. T., Hien, V. M., Smith, G. J. D., Chau, T. N. B., Hoang, D. M., Van Vinh Chau, N., Khanh, T. H., Dong, V. C., et al. (2006) · Nature Medicine · doi:10.1038/nm1477 · Cited by 1,858
Self-citation1918 Influenza: the Mother of All Pandemics
Taubenberger, J. K., & Morens, D. M. (2006) · Emerging Infectious Diseases · doi:10.3201/eid1201.050979 · Cited by 1,686
1918 Influenza: the Mother of All Pandemics
Taubenberger, J. K., & Morens, D. M. (2006) · Emerging Infectious Diseases · doi:10.3201/eid1209.05-0979 · Cited by 1,590
Emergence and pandemic potential of swine-origin H1N1 influenza virus
Neumann, G., Noda, T., & Kawaoka, Y. (2009) · Nature · doi:10.1038/nature08157 · Cited by 1,590
Metadata
- Authors
- Peiris, J., Yu, W., Leung, C., Cheung, C., Ng, W., Nicholls, J., Ng, T., Chan, K., Lai, S., Lim, W., Yuen, K., & Guan, Y.
- Affiliations
- Queen Mary Hospital (CN)
- Princess Margaret Hospital (HK)
- Department of Health (CN)
- ORCID
- Guan, Y
- Venue
- The Lancet
- Publisher
- Elsevier BV
- Published
- 2004-02
- Volume
- 363
- Issue
- 9409
- Pages
- 617-619
- ISSN
- 0099-5355 (ISSN-L)
- 0140-6736
- PMC
- PMC7112424
- OpenAlex
- W2052374402
- Cited by
- 812
- References
- 5
- Citations by year
- 2026: 5 · 2025: 10 · 2024: 13 · 2023: 20 · 2022: 22 · 2021: 20 · 2020: 20 · 2019: 22 · 2018: 26 · 2017: 20 · 2016: 10 · 2015: 32 · 2014: 42 · 2013: 47 · 2012: 40
- FWCI
- 55.80
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- The Lancet (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- The HKU Scholars Hub (University of Hong Kong) (submittedVersion)
- Funders
- Wellcome Trust
- National Institutes of Health (n01ai095357-001)
- National Institute of Allergy and Infectious Diseases (N01 AI095357, AI 95357)
- Topics
- Health Sciences › Medicine › Epidemiology › Influenza Virus Research Studies
- Health Sciences › Medicine › Epidemiology › Respiratory viral infections research
- Health Sciences › Medicine › Infectious Diseases › Viral Infections and Outbreaks Research
- Keywords
- H5N1 avian influenza, avian influenza, fatal influenza, chemokines, monokine induced by interferon-gamma, inflammatory cytokines, pathogenesis, influenza vaccine development, 2003 outbreak
- MeSH terms
- Animals, China, Disease Outbreaks, Influenza in Birds, Hong Kong, Humans, Influenza, Human, Influenza A virus, Poultry, Poultry Diseases, Zoonoses, Influenza A Virus, H5N1 Subtype
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