Cited by 850Epilepsy research and treatmentPharmacological Effects and Toxicity StudiesDiet and metabolism studies

The DOI matches its Crossref record; 317 of the 321 references it cites were found in a registry or an index.

Epilepsy in children

Guerrini, Renzo·2006·The Lancet

Open this paper in CoChat — free account

Abstract

10.5 million children worldwide are estimated to have active epilepsy. Over the past 15 years, syndrome-oriented clinical and EEG diagnosis, and better aetiological diagnosis, especially supported by neuroimaging, has helped to clarify the diversity of epilepsy in children, and has improved management. Perinatal and postinfective encephalopathy, cortical dysplasia, and hippocampal sclerosis account for the most severe symptomatic epilepsies. Ion channel defects can underlie both benign age-related disorders and severe epileptic encephalopathies with a progressive disturbance in cerebral function. However, the reasons for age-related expression in children are not understood. Neither are the mechanisms whereby an epileptic encephalopathy originates. Several new drugs have been recently introduced but have provided limited therapeutic benefits. However, treatment and quality of life have improved because the syndrome-specific efficacy profile of drugs is better known, and there is heightened awareness that compounds with severe cognitive side-effects and heavy polytherapies should be avoided. Epilepsy surgery is an important option for a few well-selected individuals, but should be considered with great caution when there is no apparent underlying brain lesion.

Integrity signals

Registry

Crossref · 10.1016/s0140-6736(06)68182-8

Cites

317 of 317 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

2 retracted

Retraction Note: Mutations in CLCN2 encoding a voltage-gated chloride channel are associated with idiopathic generalized epilepsies
Haug, K., Warnstedt, M., Alekov, A. K., Sander, T., Ramı́rez, A., Poser, B., Maljevic, S., Hebeisen, S., Kubisch, C., Rebstock, J., et al. (2009) · Nature Genetics · doi:10.1038/ng0909-1043 · Cited by 306
Retracted
Mutations in CLCN2 encoding a voltage-gated chloride channel are associated with idiopathic generalized epilepsies
Haug, K., Warnstedt, M., Alekov, A. K., Sander, T., Ramı́rez, A., Poser, B., Maljevic, S., Hebeisen, S., Kubisch, C., Rebstock, J., et al. (2003) · Nature Genetics · doi:10.1038/ng1121 · Cited by 293
Retracted
Proposal for Revised Classification of Epilepsies and Epileptic Syndromes: Commission on Classification and Terminology of the International League Against Epilepsy
(1989) · Epilepsia · doi:10.1111/j.1528-1157.1989.tb05316.x · Cited by 5,347
Early Identification of Refractory Epilepsy
Kwan, P., & Brodie, M. J. (2000) · New England Journal of Medicine · doi:10.1056/nejm200002033420503 · Cited by 5,204
Epileptic Seizures and Epilepsy: Definitions Proposed by the International League Against Epilepsy (ILAE) and the International Bureau for Epilepsy (IBE)
Fisher, R. S., Boas, W. V. E., Blume, W. T., Elger, C. E., Genton, P., Lee, P., & Engel, J. (2005) · Epilepsia · doi:10.1111/j.0013-9580.2005.66104.x · Cited by 3,678
Proposal for Revised Clinical and Electroencephalographic Classification of Epileptic Seizures
(1981) · Epilepsia · doi:10.1111/j.1528-1157.1981.tb06159.x · Cited by 3,433
Surgical Treatment of the Epilepsies
Kotagal, P. (1994) · Journal of Clinical Neurophysiology · doi:10.1097/00004691-199407000-00009 · Cited by 2,759
Epilepsy: A Comprehensive Textbook
(2008) · JAMA · doi:10.1001/jama.300.4.443-a · Cited by 2,357
A Proposed Diagnostic Scheme for People with Epileptic Seizures and with Epilepsy: Report of the ILAE Task Force on Classification and Terminology
Engel, J. (2001) · Epilepsia · doi:10.1046/j.1528-1157.2001.10401.x · Cited by 2,248
Incidence of Epilepsy and Unprovoked Seizures in Rochester, Minnesota: 1935–1984
Hauser, W. A., Annegers, J. F., & Kurland, L. T. (1993) · Epilepsia · doi:10.1111/j.1528-1157.1993.tb02586.x · Cited by 2,084
Epileptic Syndromes in Infancy, Childhood and Adolescence
Rogers, J., Bureau, M., Dravet, C., Dreifuss, F. E., Perret, A. P., Wolf, P., & Armstrong, D. L. (1993) · Journal of Neuropathology & Experimental Neurology · doi:10.1097/00005072-199307000-00012 · Cited by 1,465
Epilepsy: A Comprehensive Textbook
Vaughn, B. V. (1998) · Journal of Clinical Neurophysiology · doi:10.1097/00004691-199805000-00039 · Cited by 1,390
EPILEPSY AND THE TEMPORAL LOBES
Margerison, J. H., & Corsellis, J. (1966) · Brain · doi:10.1093/brain/89.3.499 · Cited by 1,260
A novel potassium channel gene, KCNQ2, is mutated in an inherited epilepsy of newborns
Singh, N. A., Charlier, C., Stauffer, D., DuPont, B. R., Leach, R. J., Melis, R., Ronen, G. M., Bjerre, I., Quattlebaum, T., Murphy, J. V., et al. (1998) · Nature Genetics · doi:10.1038/ng0198-25 · Cited by 1,199
A missense mutation in the neuronal nicotinic acetylcholine receptor α4 subunit is associated with autosomal dominant nocturnal frontal lobe epilepsy
Steinlein, O. K., Mulley, J. C., Propping, P., Wallace, R. H., Phillips, H. A., Sutherland, G. R., Scheffer, I. E., & Berkovic, S. F. (1995) · Nature Genetics · doi:10.1038/ng1095-201 · Cited by 1,134
Status epilepticus.
Treiman, D. M. (1996) · PubMed · Cited by 1,024
On The Cellular and Network Bases of Epileptic Seizures
McCormick, D. A., & Contreras, D. (2001) · Annual Review of Physiology · doi:10.1146/annurev.physiol.63.1.815 · Cited by 1,006
Mutational Analysis in a Cohort of 224 Tuberous Sclerosis Patients Indicates Increased Severity of TSC2, Compared with TSC1, Disease in Multiple Organs
Dabora, S. L., Jóźwiak, S., Franz, D. N., Roberts, P. S., Nieto, A., Chung, J., Choy, Y.-S., Reeve, M. P., Thiele, E. A., Egelhoff, J. C., et al. (2001) · The American Journal of Human Genetics · doi:10.1086/316951 · Cited by 998
Febrile seizures and generalized epilepsy associated with a mutation in the Na+-channel ß1 subunit gene SCN1B
Wallace, R. H., Wang, D. W., Singh, R., Scheffer, I. E., George, A. L., Phillips, H. A., Saar, K., Reis, A., Johnson, E. W., Sutherland, G. R., et al. (1998) · Nature Genetics · doi:10.1038/1252 · Cited by 996
Untitled work
(2005) · Cited by 944
Autosomal recessive lissencephaly with cerebellar hypoplasia is associated with human RELN mutations
Hong, S. E., Shugart, Y. Y., Huang, D. T.-C., Shahwan, S. A., Grant, P. E., Hourihane, J. O., Martin, N. D. T., & Walsh, C. A. (2000) · Nature Genetics · doi:10.1038/79246 · Cited by 896
A comparison of lorazepam, diazepam, and placebo for the treatment of out-of-hospital status epilepticus
Alldredge, B. K., Gelb, A. M., Isaacs, S. M., Corry, M. D., Allen, F., Ulrich, S., Gottwald, M. D., O'Neil, N., Neuhaus, J. M., Segal, M. R., et al. (2001) · New England Journal of Medicine · doi:10.1056/nejmoa002141 · Cited by 888
Mutations in filamin 1 Prevent Migration of Cerebral Cortical Neurons in Human Periventricular Heterotopia
Fox, J. W., Lamperti, E. D., Ekşioğlu, Y. Z., Hong, S. E., Feng, Y., Graham, D. A., Scheffer, I. E., Dobyns, W. B., Hirsch, B. A., Radtke, R. A., et al. (1998) · Neuron · doi:10.1016/s0896-6273(00)80651-0 · Cited by 877
Glossary of Descriptive Terminology for Ictal Semiology: Report of the ILAE Task Force on Classification and Terminology
Blume, W. T., Lüders, H. O., Mizrahi, E. M., Tassinari, C. A., Boas, W. V. E., & Engel, J. (2001) · Epilepsia · doi:10.1046/j.1528-1157.2001.22001.x · Cited by 865
Mutant GABAA receptor γ2-subunit in childhood absence epilepsy and febrile seizures
Wallace, R. H., Marini, C., Petrou, S., Harkin, L. A., Bowser, D. N., Panchal, R. G., Williams, D. A., Sutherland, G. R., Mulley, J. C., Scheffer, I. E., et al. (2001) · Nature Genetics · doi:10.1038/ng0501-49 · Cited by 780
First genetic evidence of GABAA receptor dysfunction in epilepsy: a mutation in the γ2-subunit gene
Baulac, S., Huberfeld, G., Gourfinkel‐An, I., Mitropoulou, G., Beranger, A., Prud’homme, J.-F., Baulac, M., Brice, A., Bruzzone, R., & Leguern, É. (2001) · Nature Genetics · doi:10.1038/ng0501-46 · Cited by 765
Prevalence of nonconvulsive status epilepticus in comatose patients
Towne, A. R., Waterhouse, E. J., Boggs, J. G., Garnett, L. K., Brown, A. J., Smith, J. R., & DeLorenzo, R. J. (2000) · Neurology · doi:10.1212/wnl.54.2.340 · Cited by 737
A developmental and genetic classification for malformations of cortical development
Barkovich, A. J., Kuzniecky, R., Jackson, G. D., Guerrini, R., & Dobyns, W. B. (2005) · Neurology · doi:10.1212/01.wnl.0000183747.05269.2d · Cited by 730
Self-citation
Mutation of ARX causes abnormal development of forebrain and testes in mice and X-linked lissencephaly with abnormal genitalia in humans
Kitamura, K., Yanazawa, M., Sugiyama, N., Miura, H., Iizuka‐Kogo, A., Kusaka, M., Omichi, K., Suzuki, R., Fukui, Y., Kamiirisa, K., et al. (2002) · Nature Genetics · doi:10.1038/ng1009 · Cited by 726
The Treatment of Epilepsy : Principles and Practice
Wyllie, E. (1997) · Cited by 707
The long QT syndrome
Schwartz, P. J. (1997) · Current Problems in Cardiology · doi:10.1016/s0146-2806(97)80009-6 · Cited by 693
Focal cortical dysplasia: neuropathological subtypes, EEG, neuroimaging and surgical outcome
Tassi, L. (2002) · Brain · doi:10.1093/brain/awf175 · Cited by 667
Mutation of GABRA1 in an autosomal dominant form of juvenile myoclonic epilepsy
Cossette, P., Liu, L., Brisebois, K., Dong, H., Lortie, A., Vanasse, M., Saint-Hilaire, J. M., Carmant, L., Verner, A., Lu, W.-Y., et al. (2002) · Nature Genetics · doi:10.1038/ng885 · Cited by 659
Efficacy and tolerability of the new antiepileptic drugs I: Treatment of new onset epilepsy [RETIRED]
French, J. A., Kanner, A. M., Bautista, J. F., Abou‐Khalil, B., Browne, T. R., Harden, C. L., Theodore, W. H., Bazil, C. W., Stern, J. M., Schachter, S. C., et al. (2004) · Neurology · doi:10.1212/01.wnl.0000123693.82339.fc · Cited by 654
Epileptology of the first-seizure presentation: a clinical, electroencephalographic, and magnetic resonance imaging study of 300 consecutive patients
King, M. A., Newton, M. R., Jackson, G. D., Fitt, G. J., Mitchell, L. A., Silvapulle, M. J., & Berkovic, S. F. (1998) · The Lancet · doi:10.1016/s0140-6736(98)03543-0 · Cited by 632
Factors Prognostic of Unprovoked Seizures after Febrile Convulsions
Annegers, J. F., Hauser, W. A., Shirts, S. B., & Kurland, L. T. (1987) · New England Journal of Medicine · doi:10.1056/nejm198702263160901 · Cited by 631
Mutations in LGI1 cause autosomal-dominant partial epilepsy with auditory features
Kalachikov, S. M., Evgrafov, O. V., Ross, B., Winawer, M. R., Barker‐Cummings, C., Boneschi, F. M., Choi, C., Morozov, P. S., Das, K., Teplitskaya, E., et al. (2002) · Nature Genetics · doi:10.1038/ng832 · Cited by 617
Phenobarbital Compared with Phenytoin for the Treatment of Neonatal Seizures
Painter, M. J., Scher, M. S., Stein, A. D., Armatti, S., Wang, Z., Gardiner, J. C., Paneth, N., Minnigh, B., & Alvin, J. D. (1999) · New England Journal of Medicine · doi:10.1056/nejm199908123410704 · Cited by 615
The Efficacy of the Ketogenic Diet—1998: A Prospective Evaluation of Intervention in 150 Children
Freeman, J. M., Vining, E. P. G., Pillas, D. J., Pyzik, P. L., Casey, J. C., & Kelly, L. A. M. T. (1998) · PEDIATRICS · doi:10.1542/peds.102.6.1358 · Cited by 613
Stiripentol in severe myoclonic epilepsy in infancy: a randomised placebo-controlled syndrome-dedicated trial
Chiron, C., Marchand, M., Tran, A., Rey, E., d'Athis, P., Vincent, J., Dulac, O., & Pons, G. (2000) · The Lancet · doi:10.1016/s0140-6736(00)03157-3 · Cited by 568
Phenobarbital for Febrile Seizures — Effects on Intelligence and on Seizure Recurrence
Farwell, J. R., Lee, Y. J., Hirtz, D. G., Sulzbacher, S. I., Ellenberg, J. H., & Nelson, K. B. (1990) · New England Journal of Medicine · doi:10.1056/nejm199002083220604 · Cited by 562
Seizures after head trauma
Annegers, J. F., Grabow, J. D., Groover, R. V., Laws, E. R., Elveback, L. R., & Kurland, L. T. (1980) · Neurology · doi:10.1212/wnl.30.7.683 · Cited by 550
Radicals r'aging
Wallace, D. C., & Melov, S. (1998) · Nature Genetics · doi:10.1038/448 · Cited by 548
G Protein-Coupled Receptor-Dependent Development of Human Frontal Cortex
Piao, X., Hill, R. S., Bodell, A., Chang, B. S., Basel-Vanagaite, L., Straussberg, R., Dobyns, W. B., Qasrawi, B., Winter, R. M., Innes, A. M., et al. (2004) · Science · doi:10.1126/science.1092780 · Cited by 517
Seizure outcome after epilepsy surgery in children and adolescents
Wyllie, E., Comair, Y. G., Kotagal, P., Bulacio, J. C., Bingaman, W. E., & Ruggieri, P. M. (1998) · Annals of Neurology · doi:10.1002/ana.410440507 · Cited by 511
The Treatment of Epilepsy
(2004) · Wiley eBooks · doi:10.1002/9780470752463 · Cited by 509
Antiepileptogenesis and Seizure Prevention Trials with Antiepileptic Drugs: Meta‐Analysis of Controlled Trials
Temkin, N. (2001) · Epilepsia · doi:10.1046/j.1528-1157.2001.28900.x · Cited by 501
Pathophysiological Mechanisms of Brain Damage from Status Epilepticus
Wasterlain, C. G., Fujikawa, D. G., Penix, L. P., & Sankar, R. (1993) · Epilepsia · doi:10.1111/j.1528-1157.1993.tb05905.x · Cited by 474
Lamotrigine and Seizure Aggravation in Severe Myoclonic Epilepsy
Guerrini, R., Dravet, C., Genton, P., Belmonte, A., Kaminska, A., & Dulac†, O. (1998) · Epilepsia · doi:10.1111/j.1528-1157.1998.tb01413.x · Cited by 467
Self-citation
A Multicenter Study of the Efficacy of the Ketogenic Diet
Vining, E. P. G. (1998) · Archives of Neurology · doi:10.1001/archneur.55.11.1433 · Cited by 461
The nicotinic receptor β2 subunit is mutant in nocturnal frontal lobe epilepsy
Fusco, M. D., Becchetti, A., Patrignani, A., Annesi, G., Gambardella, A., Quattrone, A., Ballabio, A., Wanke, E., & Casari, G. (2000) · Nature Genetics · doi:10.1038/81566 · Cited by 447
Magnetic resonance imaging evidence of hippocampal injury after prolonged focal febrile convulsions
VanLandingham, K., Heinz, E. R., Cavazos, J. E., & Lewis, D. V. (1998) · Annals of Neurology · doi:10.1002/ana.410430403 · Cited by 444
Truncation of the GABAA-Receptor γ2 Subunit in a Family with Generalized Epilepsy with Febrile Seizures Plus
Harkin, L. A., Bowser, D. N., Dibbens, L. M., Singh, R., Phillips, F., Wallace, R. H., Richards, M. C., Williams, D. A., Mulley, J. C., Berkovic, S. F., et al. (2002) · The American Journal of Human Genetics · doi:10.1086/338710 · Cited by 441
Mutations in the human ortholog of Aristaless cause X-linked mental retardation and epilepsy
Strømme, P., Mangelsdorf, M., Shaw, M. A., Lower, K. M., Lewis, M. E. S., Bruyèrè, H., Lütcherath, V., Gedeon, Á. K., Wallace, R. H., Scheffer, I. E., et al. (2002) · Nature Genetics · doi:10.1038/ng862 · Cited by 440
The Development of the Electroencephalogram in Normal Children from the Age of 1 Through 15 Years – Paroxysmal activity
Eeg‐Olofsson, O., Petersén, I., & Selldén, U. (1971) · Neuropediatrics · doi:10.1055/s-0028-1091791 · Cited by 439
Some Aspects of Prognosis in the Epilepsies: A Review
Sander, J. W. A. S. (1993) · Epilepsia · doi:10.1111/j.1528-1157.1993.tb02126.x · Cited by 414
Efficacy of Felbamate in Childhood Epileptic Encephalopathy (Lennox-Gastaut Syndrome)
The Felbamate Study Group in Lennox-Gastaut Syndrome (1993) · New England Journal of Medicine · doi:10.1056/nejm199301073280105 · Cited by 411
Epilepsies in twins: Genetics of the major epilepsy syndromes
Berkovic, S. F., Howell, R. A., Hay, D. A., & Hopper, J. L. (1998) · Annals of Neurology · doi:10.1002/ana.410430405 · Cited by 410
Efficacy and tolerability of the new antiepileptic drugs II: Treatment of refractory epilepsy [RETIRED]
French, J. A., Kanner, A. M., Bautista, J. F., Abou‐Khalil, B., Browne, T. R., Harden, C. L., Theodore, W. H., Bazil, C. W., Stern, J. M., Schachter, S. C., et al. (2004) · Neurology · doi:10.1212/01.wnl.0000123695.22623.32 · Cited by 407
Buccal midazolam and rectal diazepam for treatment of prolonged seizures in childhood and adolescence: a randomised trial
Scott, R. C., Besag, F. M., & Neville, B. G. (1999) · The Lancet · doi:10.1016/s0140-6736(98)06425-3 · Cited by 393
Early‐ and Late‐onset Complications of the Ketogenic Diet for Intractable Epilepsy
Kang, H., Chung, D. E., Kim, D. W., & Kim, H. D. (2004) · Epilepsia · doi:10.1111/j.0013-9580.2004.10004.x · Cited by 391
Hippocampal sclerosis in temporal lobe epilepsy demonstrated by magnetic resonance imaging
Berkovic, S. F., Andermann, F., Olivier, A., Ethier, R., Melanson, D., ROBITAILLE, Y., Kuzniecky, R., Peters, T. M., & Feindel, W. (1991) · Annals of Neurology · doi:10.1002/ana.410290210 · Cited by 390
Mutations in ARFGEF2 implicate vesicle trafficking in neural progenitor proliferation and migration in the human cerebral cortex
Sheen, V. L., Ganesh, V. S., Topçu, M., Sébire, G., Bodell, A., Hill, R. S., Grant, P. E., Shugart, Y. Y., Imitola, J., Khoury, S. J., et al. (2003) · Nature Genetics · doi:10.1038/ng1276 · Cited by 389
Self-citation
Landau—Kleffner syndrome
Morrell, F., Whisler, W. W., Smith, M. C., Hoeppner, T. J., de Toledo‐Morrell, L., Pierre-Louis, S. J. C., Kanner, A. M., Buclow, J. M., Ristanovic, R. K., Bergen, D. C., et al. (1995) · Brain · doi:10.1093/brain/118.6.1529 · Cited by 388
A double-blind, randomized trial of topiramate in Lennox–Gastaut syndrome
Sachdeo, R. C., Glauser, T. A., Ritter, F. J., Reife, R., Lim, P., Pledger, G. W., & the Topiramate YL Study Group (1999) · Neurology · doi:10.1212/wnl.52.9.1882 · Cited by 380
Emerging insights into the genesis of epilepsy
McNamara, J. O. (1999) · Nature · doi:10.1038/399a015 · Cited by 378
Ketonemia and Seizures: Metabolic and Anticonvulsant Effects of Two Ketogenic Diets in Childhood Epilepsy
Huttenlocher, P. R. (1976) · Pediatric Research · doi:10.1203/00006450-197605000-00006 · Cited by 376
Occipital lobe epilepsy: Clinical characteristics, seizure spread patterns, and results of surgery
Williamson, P. D., Thadani, V. M., Darcey, T. M., Spencer, D. D., Spencer, S. S., & Mattson, R. H. (1992) · Annals of Neurology · doi:10.1002/ana.410310103 · Cited by 371
Clinical outcomes of hemispherectomy for epilepsy in childhood and adolescence
Devlin, A. M. (2003) · Brain · doi:10.1093/brain/awg052 · Cited by 359
Lamotrigine for Generalized Seizures Associated with the Lennox–Gastaut Syndrome
Motte, J., Trevathan, E., Arvidsson, J. F. V., Barrera, M. N., Mullens, E. L., & Manasco, P. K. (1997) · New England Journal of Medicine · doi:10.1056/nejm199712183372504 · Cited by 359
Incidence and prevalence
Forsgren, L. (2004) · CRC Press eBooks · doi:10.1201/b13560-9 · Cited by 352
Influence of mutation type and X chromosome inactivation on Rett syndrome phenotypes
Amir, R. E., den Veyver, I. B. V., Schultz, R., Malicki, D. M., Tran, C. Q., Dahle, E. J., Philippi, A., Tímár, L., Percy, A. K., Motil, K. J., et al. (2000) · Annals of Neurology · doi:10.1002/1531-8249(200005)47:5 · Cited by 351
High-dose Corticotropin (ACTH) Versus Prednisone for Infantile Spasms: A Prospective, Randomized, Blinded Study
Baram, T. Z., Mitchell, W. C., Tournay, A. E., Snead, O. C., Hanson, R., & Horton, E. J. (1996) · PEDIATRICS · doi:10.1542/peds.97.3.375 · Cited by 341
Cognitive impairment during epileptiform discharges: is it ever justifiable to treat the EEG?
Binnie, C. D. (2003) · The Lancet Neurology · doi:10.1016/s1474-4422(03)00584-2 · Cited by 332
Abnormal cerebral structure in juvenile myoclonic epilepsy demonstrated with voxel-based analysis of MRI
Woermann, F. G., Free, S. L., Koepp, M. J., Sisodiya, S. M., & Duncan, J. S. (1999) · Brain · doi:10.1093/brain/122.11.2101 · Cited by 331
The Risk of Seizures after Receipt of Whole-Cell Pertussis or Measles, Mumps, and Rubella Vaccine
Barlow, W. E., Davis, R. L., Glasser, J. W., Rhodes, P. H., Thompson, R. S., Mullooly, J. P., BLACK, S. B., Shinefield, H. R., Ward, J. I., Marcy, S. M., et al. (2001) · New England Journal of Medicine · doi:10.1056/nejmoa003077 · Cited by 325
Severe myoclonic epilepsy in infancy: Dravet syndrome.
Dravet, C., Bureau, M., Oguni, H., Fukuyama, Y., & Çokar, Ö. (2005) · PubMed · Cited by 319
Cerebral hemispherectomy
Jonas, R., Nguyen, S. T. T., Hu, B., Asarnow, R. F., LoPresti, C. M., Curtiss, S., de Bode, S., Yudovin, S., Shields, W. D., Vinters, H. V., et al. (2004) · Neurology · doi:10.1212/01.wnl.0000127109.14569.c3 · Cited by 316
Randomized trial comparing vigabatrin and hydrocortisone in infantile spasms due to tuberous sclerosis
Chiron, C., Dumas, C. M., Jambaqué, I., Mumford, J. P., & Dulac, O. (1997) · Epilepsy Research · doi:10.1016/s0920-1211(96)01006-6 · Cited by 310
How long does it take for partial epilepsy to become intractable?
Berg, A. T., Langfitt, J. T., Shinnar, S., Vickrey, B. G., Sperling, M. R., Walczak, T. S., Bazil, C. W., Pacia, S. V., & Spencer, S. S. (2003) · Neurology · doi:10.1212/01.wnl.0000031792.89992.ec · Cited by 304
Experience With the Ketogenic Diet in Infants
Nordli, D. R., Kuroda, M. M., Carroll, J., Koenigsberger, D. Y., Hirsch, L. J., Bruner, H. J., Seidel, W. T., & Vivo, D. C. D. (2001) · PEDIATRICS · doi:10.1542/peds.108.1.129 · Cited by 303
The Risk of Seizure Recurrence After a First Unprovoked Afebrile Seizure in Childhood: An Extended Follow-up
Shinnar, S., Berg, A. T., Moshé, S. L., O’Dell, C., Alemany, M., Newstein, D., Kang, H., Goldensohn, E. S., & Hauser, W. A. (1996) · PEDIATRICS · doi:10.1542/peds.98.2.216 · Cited by 302
A randomized, placebo-controlled study of topiramate in primary generalized tonic-clonic seizures
Biton, V., Montouris, G., Ritter, F. J., Riviello, J. J., Reife, R., Lim, P., Pledger, G. W., & the Topiramate YTC Study Group (1999) · Neurology · doi:10.1212/wnl.52.7.1330 · Cited by 295
Benign familial neonatal‐infantile seizures: Characterization of a new sodium channelopathy
Berkovic, S. F., Heron, S. E., Giordano, L., Marini, C., Guerrini, R., Kaplan, R. E., Gambardella, A., Steinlein, O. K., Grinton, B. E., Dean, J. T., et al. (2004) · Annals of Neurology · doi:10.1002/ana.20029 · Cited by 285
Self-citation
The Impact of Childhood Epilepsy on Neurocognitive and Behavioral Performance: A Prospective Longitudinal Study
Bailet, L. L., & Turk, W. R. (2000) · Epilepsia · doi:10.1111/j.1528-1157.2000.tb00184.x · Cited by 282
Relation of photosensitivity to epileptic syndromes.
Wolf, P., & Goosses, R. (1986) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.49.12.1386 · Cited by 282
A Splice-Site Mutation in GABRG2 Associated With Childhood Absence Epilepsy and Febrile Convulsions
Kananura, C., Haug, K., Sander, T., Runge, U., Gu, W., Hallmann, K., Rebstock, J., Heils, A., & Steinlein, O. K. (2002) · Archives of Neurology · doi:10.1001/archneur.59.7.1137 · Cited by 280
Autosomal dominant nocturnal frontal lobe epilepsy. A video- polysomnographic and genetic appraisal of 40 patients and delineation of the epileptic syndrome
Oldani, A. (1998) · Brain · doi:10.1093/brain/121.2.205 · Cited by 280
Seizures and Other Neurologic Sequelae of Bacterial Meningitis in Children
Pomeroy, S. L., Holmes, S. J., Dodge, P. R., & Feigin, R. D. (1990) · New England Journal of Medicine · doi:10.1056/nejm199012133232402 · Cited by 280
Treatment of infantile spasms
Hancock, E. C., Osborne, J. P., & Edwards, S. W. (2013) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd001770.pub3 · Cited by 274
EEG criteria predictive of complicated evolution in idiopathic rolandic epilepsy
Massa, R., Martin, A. D. S., Carcangiu, R., Rudolf, G., Seegmüller, C., Kleitz, C., Metz‐Lutz, M., Hirsch, É., & Marescaux, C. (2001) · Neurology · doi:10.1212/wnl.57.6.1071 · Cited by 274
Divalproex Treatment for Youth With Explosive Temper and Mood Lability: A Double-Blind, Placebo-Controlled Crossover Design
Donovan, S. J., Stewart, J. W., Nunes, E. V., Quitkin, F. M., Parides, M., Daniel, W., Susser, E., & Klein, D. F. (2000) · American Journal of Psychiatry · doi:10.1176/appi.ajp.157.5.818 · Cited by 273
Newly Diagnosed Epilepsy in Children: Presentation at Diagnosis
Berg, A. T., Shinnar, S., Levy, S. R., & Testa, F. M. (1999) · Epilepsia · doi:10.1111/j.1528-1157.1999.tb00739.x · Cited by 270
Vigabatrin Versus ACTH as First‐Line Treatment for Infantile Spasms: A Randomized, Prospective Study
Vigevano, P., & Cilio, M. R. (1997) · Epilepsia · doi:10.1111/j.1528-1157.1997.tb00063.x · Cited by 270
Surgical treatment of limbic epilepsy associated with extrahippocampal lesions: the problem of dual pathology
Levesque, M. F., Nakasato, N., Vinters, H. V., & Babb, T. L. (1991) · Journal of neurosurgery · doi:10.3171/jns.1991.75.3.0364 · Cited by 266
The Epileptic Seizure
(1958) · Neurology · doi:10.1212/wnl.8.1.85 · Cited by 265
Cognitive side effects of antiepileptic drugs in children
Loring, D. W., & Meador, K. J. (2004) · Neurology · doi:10.1212/01.wnl.0000115653.82763.07 · Cited by 264
Randomised comparative monotherapy trial of phenobarbitone, phenytoin, carbamazepine, or sodium valproate for newly diagnosed childhood epilepsy
de Silva, M., Macardle, B. M., McGowan, M., Hughes, E., Stewart, J. A., Reynolds, E. H., Hughes, E., Neville, B. G. R., & Johnson, A. L. (1996) · The Lancet · doi:10.1016/s0140-6736(96)90074-4 · Cited by 261
A Prospective Study of Recurrent Febrile Seizures
Berg, A. T., Shinnar, S., Hauser, W. A., Alemany, M., Shapiro, E. D., Salomon, M. E., & Crain, E. F. (1992) · New England Journal of Medicine · doi:10.1056/nejm199210153271603 · Cited by 257
Myokymia and neonatal epilepsy caused by a mutation in the voltage sensor of the KCNQ2 K + channel
Dedek, K., Kunath, B., Kananura, C., Reuner, U., Jentsch, T. J., & Steinlein, O. K. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.211431298 · Cited by 252
Atypical Benign Partial Epilepsy of Childhood
Aicardi, J. F., & Chevrie, J. J. (1982) · Developmental Medicine & Child Neurology · doi:10.1111/j.1469-8749.1982.tb13620.x · Cited by 251
Hippocampal malformation as a cause of familial febrile convulsions and subsequent hippocampal sclerosis
Fernández, G., Effenberger, O., Vinz, B., Steinlein, O. K., Elger, C. E., Döhring, W., & Heinze, H. J. (1998) · Neurology · doi:10.1212/wnl.50.4.909 · Cited by 251
Topiramate, carbamazepine and valproate monotherapy: double-blind comparison in newly diagnosed epilepsy
Privitera, M., Brodie, M. J., Mattson, R. H., Chadwick, D. W., Neto, W., Wang, S., & for the EPMN 105 Study Group (2003) · Acta Neurologica Scandinavica · doi:10.1034/j.1600-0404.2003.00093.x · Cited by 251
Spectrum ofSCN1Amutations in severe myoclonic epilepsy of infancy
Nabbout, R., Gennaro, E., Bernardina, B. D., Dulac, O., Madia, F., Bertini, E., Capovilla, G., Chiron, C., Cristofori, G., Elia, M., et al. (2003) · Neurology · doi:10.1212/01.wnl.0000069463.41870.2f · Cited by 245
Self-citation
Epileptic Seizures: Pathophysiology And Clinical Semiology
Lüders, H. O., & Noachtar, S. (2000) · Cited by 241
A double-blind controlled clinical trial of oxcarbazepine versus phenytoin in children and adolescents with epilepsy
Guerreiro, M. M., Vigonius, U., Pohlmann, H., de Manreza, M. L. G., Fejerman, N., Antoniuk, S. A., & Moore, A. (1997) · Epilepsy Research · doi:10.1016/s0920-1211(97)00025-9 · Cited by 241
Efficacy of the Ketogenic Diet for Infantile Spasms
Kossoff, E. H., Pyzik, P. L., McGrogan, J. R., Vining, E. P. G., & Freeman, J. M. (2002) · PEDIATRICS · doi:10.1542/peds.109.5.780 · Cited by 235
A double-blind, randomized trial of topiramate as adjunctive therapy for partial-onset seizures in children
Elterman, R. D., Glauser, T. A., Wyllie, E., Reife, R., Wu, S., Pledger, G. W., & the Topiramate YP Study Group (1999) · Neurology · doi:10.1212/wnl.52.7.1338 · Cited by 235
Randomised, Placebo‐Controlled Study of Vigabatrin as First‐Line Treatment of Infantile Spasms
Appleton, R. E., Peters, A. C. B., Mumford, J. P., & Shaw, D. (1999) · Epilepsia · doi:10.1111/j.1528-1157.1999.tb02049.x · Cited by 235
The Cognitive Outcome of Hemispherectomy in 71 Children
Pulsifer, M. B., Brandt, J., Salorio, C. F., Vining, E. P. G., Carson, B. S., & Freeman, J. M. (2004) · Epilepsia · doi:10.1111/j.0013-9580.2004.15303.x · Cited by 227
Paroxysmal Nonepileptic Events in Children and Adolescents
Kotagal, P., Costa, M., Wyllie, E., & Wolgamuth, B. R. (2002) · PEDIATRICS · doi:10.1542/peds.110.4.e46 · Cited by 227
The course of benign partial epilepsy of childhood with centrotemporal spikes
Bouma, P. A. D., Bovenkerk, A., Westendorp, R. G. J., & Brouwer, O. F. (1997) · Neurology · doi:10.1212/wnl.48.2.430 · Cited by 224
Randomized trial of vigabatrin in patients with infantile spasms
Elterman, R. D., Shields, W. D., Mansfield, K. A., Nakagawa, J. A., & the US Infantile Spasms Vigabatrin Study Group (2001) · Neurology · doi:10.1212/wnl.57.8.1416 · Cited by 224
Neurocysticercosis and epilepsy in developing countries
Pal, D. K. (2000) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.68.2.137 · Cited by 219
Lamictal (Lamotrigine) Monotherapy for Typical Absence Seizures in Children
Frank, L. M., Enlow, T. C., Holmes, G. L., Manasco, P. K., Concannon, S., Chen, C., Womble, G. P., & Casale, E. J. (1999) · Epilepsia · doi:10.1111/j.1528-1157.1999.tb00805.x · Cited by 218
Risk of Seizure Recurrence Following a First Unprovoked Seizure in Childhood: A Prospective Study
Shinnar, S., Berg, A. T., Moshé, S. L., Petix, M., Maytal, J., Kang, H., Goldensohn, E. S., & Hauser, W. A. (1990) · PEDIATRICS · doi:10.1542/peds.85.6.1076 · Cited by 217
DEVELOPMENT OF INTELLIGENCE AND MEMORY IN CHILDREN WITH HEMIPLEGIC CEREBRAL PALSY
Vargha‐Khadem, F., Isaacs, E., van der Werf, S. P., Robb, S. A., & Wilson, J. (1992) · Brain · doi:10.1093/brain/115.1.315 · Cited by 215
Mental and behavioural outcome of infantile epilepsy treated by vigabatrin in tuberous sclerosis patients
Jambaqué, I., Chiron, C., Dumas, C. M., Mumford, J. P., & Dulac, O. (2000) · Epilepsy Research · doi:10.1016/s0920-1211(99)00082-0 · Cited by 213
Long‐term Cognitive Outcomes of a Cohort of Children with Cryptogenic Infantile Spasms Treated with High‐dose Adrenocorticotropic Hormone
Kivity, S., Lerman, P., Ariel, R., Danziger, Y., Mimouni, M., & Shinnar, S. (2004) · Epilepsia · doi:10.1111/j.0013-9580.2004.30503.x · Cited by 211
Landau‐Kleffner Syndrome: A Pharmacologic Study of Five Cases
Marescaux, C., Hirsch, É., Finck, S., Maquet, P., Schlumberger, É., Sellal, F., Metz‐Lutz, M., Alembik, Y., Salmon, É., Franck, G., et al. (1990) · Epilepsia · doi:10.1111/j.1528-1157.1990.tb05518.x · Cited by 211
Long‐Term Outcome of West Syndrome: A Study of Adults with a History of Infantile Spasms
Riikonen, R. (1996) · Epilepsia · doi:10.1111/j.1528-1157.1996.tb00573.x · Cited by 204
Magnetic resonance imaging in childhood intractable partial epilepsies
Kuzniecky, R., Murro, A. M., King, D., Morawetz, R. B., Smith, J. S., Powers, R. E., Yaghmai, F., Faught, E., Gallagher, B. B., & Snead, O. C. (1993) · Neurology · doi:10.1212/wnl.43.4.681 · Cited by 203
Idiopathic Photosensitive Occipital Lobe Epilepsy
Guerrini, R., Dravet, C., Genton, P., Bureau, M., Bonanni, P., Ferrari, A. R., & Roger, J. (1995) · Epilepsia · doi:10.1111/j.1528-1157.1995.tb01631.x · Cited by 203
Self-citation
The Epidemiology and Natural History of Infantile Spasms
Cowan, L. D., & Hudson, L. S. (1991) · Journal of Child Neurology · doi:10.1177/088307389100600412 · Cited by 202
Valproic acid versus ethosuximide in the treatment of absence seizures
Sato, S., WHITE, B. G., Penry, J. K., Dreifuss, F. E., Sackellares, J. C., & Kupferberg, H. J. (1982) · Neurology · doi:10.1212/wnl.32.2.157 · Cited by 200
Treatment and Long-Term Prognosis of Myoclonic-Astatic Epilepsy of Early Childhood
Oguni, H., Tanaka, T., Hayashi, K., Funatsuka, M., Sakauchi, M., Shirakawa, S., & Osawa, M. (2002) · Neuropediatrics · doi:10.1055/s-2002-33675 · Cited by 199
Severe Myoclonic Epilepsy of Infancy: Extended Spectrum of GEFS+?
Singh, R., Andermann, E., Whitehouse, W. P., Harvey, A. S., Keene, D. L., Seni, M., Crossland, K. M., Andermann, F., Berkovic, S. F., & Scheffer, I. E. (2001) · Epilepsia · doi:10.1046/j.1528-1157.2001.042007837.x · Cited by 199
Death in children with epilepsy: a population-based study
Camfield, C., CAMFIELD, P. R., & Veugelers, P. J. (2002) · The Lancet · doi:10.1016/s0140-6736(02)08779-2 · Cited by 195
Lamotrigine for Generalized Seizures Associated with the Lennox–Gastaut Syndrome
Trevathan, E., Mullens, E. L., & Manasco, P. K. (1998) · New England Journal of Medicine · doi:10.1056/nejm199809173391218 · Cited by 194
Chromosomal Abnormalities and Epilepsy: A Review for Clinicians and Gene Hunters
Singh, R., Gardner, R. J. M., Crossland, K. M., Scheffer, I. E., & Berkovic, S. F. (2002) · Epilepsia · doi:10.1046/j.1528-1157.2002.19498.x · Cited by 193
Epilepsy after a first unprovoked seizure in childhood
CAMFIELD, P. R., Camfield, C., Dooley, J. M., Tibbles, J. A. R., Fung, T., & Garner, B. (1985) · Neurology · doi:10.1212/wnl.35.11.1657 · Cited by 189
The Treatment of Epilepsy: Principles and Practice
Ronen, G. M. (2002) · JAMA · doi:10.1001/jama.287.11.1466 · Cited by 189
Epilepsy Surgery in Children with Focal Cortical Dysplasia (FCD): Results of Long-Term Seizure Outcome
Kloss, S., Pieper, T., Pannek, H., Holthausen, H., & Tuxhorn, I. (2002) · Neuropediatrics · doi:10.1055/s-2002-23595 · Cited by 189
Treatment of Lennox-Gastaut syndrome
Hancock, E. C., & Cross, J. H. (2013) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd003277.pub3 · Cited by 188
Temporal lobe epilepsy due to hippocampal sclerosis in pediatric candidates for epilepsy surgery
Mohamed, A., Wyllie, E., Ruggieri, P. M., Kotagal, P., Babb, T. L., Hilbig, A., Wylie, C., Ying, Z., Staugaitis, S. M., Najm, I., et al. (2001) · Neurology · doi:10.1212/wnl.56.12.1643 · Cited by 179
Antiepileptic Drug‐Induced Worsening of Seizures in Children
Guerrini, R., Belmonte, A., & Genton, P. (1998) · Epilepsia · doi:10.1111/j.1528-1157.1998.tb05118.x · Cited by 179
Self-citation
Late Cognitive Effects of Early Treatment with Phenobarbital
Sulzbacher, S. I., Farwell, J. R., Temkin, N. R., Lu, A. S., & Hirtz, D. G. (1999) · Clinical Pediatrics · doi:10.1177/000992289903800702 · Cited by 176
Experience with immunomodulatory treatments in Rasmussen’s encephalitis
Granata, T., Fusco, L., Gobbi, G., Freri, E., Ragona, F., Broggi, G., Mantegazza, R., Giordano, L., Villani, F. S., Capovilla, G., et al. (2003) · Neurology · doi:10.1212/01.wnl.0000099074.04539.e0 · Cited by 174
Adjunctive therapy with oxcarbazepine in children with partial seizures
Glauser, T. A., Nigro, M. A., Sachdeo, R., Pasteris, L. A., Weinstein, S. L., Abou‐Khalil, B., Frank, L. M., Grinspan, A., Guarino, T., Bettis, D. B., et al. (2000) · Neurology · doi:10.1212/wnl.54.12.2237 · Cited by 174
Functional MR of frontal lobe activation: comparison with Wada language results.
Yetkin, F. Z., Swanson, S. J., Fischer, M., Akansel, G., Morris, G. L., Mueller, W. M., & Haughton, V. M. (1998) · PubMed Central · Cited by 173
Syndromes of bilateral symmetrical polymicrogyria.
Barkovich, A. J., Hevner, R. F., & Guerrini, R. (2000) · PubMed · Cited by 169
Self-citation
The Descriptive Epidemiology of Infantile Spasms Among Atlanta Children
Trevathan, E., Murphy, C. C., & Yeargin‐Allsopp, M. (1999) · Epilepsia · doi:10.1111/j.1528-1157.1999.tb00773.x · Cited by 168
Multilobar polymicrogyria, intractable drop attack seizures, and sleep-related electrical status epilepticus
Guerrini, R., Genton, P., Bureau, M., Parmeggiani, A., Salas‐Puig, X., Santucci, M., Bonanni, P., Ambrosetto, G., & Dravet, C. (1998) · Neurology · doi:10.1212/wnl.51.2.504 · Cited by 168
Self-citation
A MULTICENTRE COMPARATIVE TRIAL OF SODIUM VALPROATE AND CARBAMAZEPINE IN PAEDIATRIC EPILEPSY
Verity, C. M., Hosking, G. P., & Easter, D. J. (1995) · Developmental Medicine & Child Neurology · doi:10.1111/j.1469-8749.1995.tb11978.x · Cited by 164
Visual Sensitivity and Epilepsy: A Proposed Terminology and Classification for Clinical and EEG Phenomenology
Trenité, D. G. A. K.-N., Guerrini, R., Binnie, C. D., & Genton, P. (2001) · Epilepsia · doi:10.1046/j.1528-1157.2001.30600.x · Cited by 163
Self-citation
Familial schizencephaly associated with EMX2 mutation
Granata, T., Farina, L., Faiella, A., Cardini, R., D’Incerti, L., Boncinelli, E., & Battaglia, G. (1997) · Neurology · doi:10.1212/wnl.48.5.1403 · Cited by 162
Effect of prehospital treatment on the outcome of status epilepticus in children
Alldredge, B. K., Pharm, D., Wall, D. B., & Ferriero, D. M. (1995) · Pediatric Neurology · doi:10.1016/0887-8994(95)00044-g · Cited by 162
Linkage mapping of benign familial infantile convulsions (BFIC) to chromosome 19q
Guipponi, M., Rivier, F., Vigevano, F., Beck, C., Crespel, A., Échenne, B., Lucchini, P., Sebastianelli, R., Baldy-Moulinier, M., & Malafosse, A. (1997) · Human Molecular Genetics · doi:10.1093/hmg/6.3.473 · Cited by 162
Efficacy and Safety of Levetiracetam in Children with Partial Seizures: An Open‐label Trial
Glauser, T. A., Pellock, J. M., Bebin, E. M., Fountain, N. B., Ritter, F. J., Jensen, C. M., & Shields, W. D. (2002) · Epilepsia · doi:10.1046/j.1528-1157.2002.13101.x · Cited by 160
Childhood absence epilepsy and febrile seizures: a family with a GABAA receptor mutation
Marini, C., Harkin, L. A., Wallace, R. H., Mulley, J. C., Scheffer, I. E., & Berkovic, S. F. (2002) · Brain · doi:10.1093/brain/awg018 · Cited by 160
Sulthiame as Monotherapy in Children with Benign Childhood Epilepsy with Centrotemporal Spikes: A 6‐Month Randomized, Double‐Blind, Placebo‐Controlled Study
Rating, D., Wolf, C., & Bast, T. (2000) · Epilepsia · doi:10.1111/j.1528-1157.2000.tb04606.x · Cited by 156
Anterior callosotomy in the treatment of medically intractable epilepsies: A study of 43 patients with a mean follow‐up of 39 months
Oguni, H., Olivier, A., Andermann, F., & Comair, J. (1991) · Annals of Neurology · doi:10.1002/ana.410300307 · Cited by 156
Hippocampal sclerosis in epilepsy and childhood febrile seizures
Cook, M. J., Fish, D. R., Shorvon, S. D., Stevens, J., & Kuks, J. B. M. (1993) · The Lancet · doi:10.1016/0140-6736(93)92754-h · Cited by 156
Germline and mosaic mutations of FLN1 in men with periventricular heterotopia
Guerrini, R., Mei, D., Sisodiya, S. M., Sicca, F., Harding, B. N., Takahashi, Y., Dorn, T., Yoshida, A., Campistol, J., Krämer, G., et al. (2004) · Neurology · doi:10.1212/01.wnl.0000132818.84827.4d · Cited by 155
Self-citation
How Well Can Epilepsy Syndromes Be Identified at Diagnosis? A Reassessment 2 Years After Initial Diagnosis
Berg, A. T., Shinnar, S., Levy, S. R., Testa, F. M., Smith‐Rapaport, S., & Beckerman, B. (2000) · Epilepsia · doi:10.1111/j.1528-1157.2000.tb04604.x · Cited by 154
Lack of cortical contrast gain control in human photosensitive epilepsy
Porciatti, V., Bonanni, P., Fiorentini, A., & Guerrini, R. (2000) · Nature Neuroscience · doi:10.1038/72972 · Cited by 152
Self-citation
Lamotrigine for the treatment of epilepsy in childhood
Besag, F., Wallace, S. J., Dulac, O., Alving, J., Spencer, S. C., & Hosking, G. P. (1995) · The Journal of Pediatrics · doi:10.1016/s0022-3476(95)70047-1 · Cited by 151
A dose-comparison trial of topiramate as monotherapy in recently diagnosed partial epilepsy
Gilliam, F. G., Veloso, F., Bomhof, M. A. M., Gazda, S. K., Biton, V., ter Bruggen, J. P., Neto, W., Bailey, C., Pledger, G. W., Wu, S., et al. (2003) · Neurology · doi:10.1212/01.wnl.0000048200.12663.bc · Cited by 149
The risks of seizure disorders among relatives of patients with childhood onset epilepsy
Annegers, J. F., Hauser, W. A., Anderson, V. E., & Kurland, L. T. (1982) · Neurology · doi:10.1212/wnl.32.2.174 · Cited by 148
Diamondoids and oil are not forever
Schoell, M., & Carlson, R. M. K. (1999) · Nature · doi:10.1038/19847 · Cited by 147
WHAT TYPES OF EPILEPSY ARE PRECEDED BY FEBRILE SEIZURES? A POPILATION‐BASED STUDY OF CHILDREN
CAMFIELD, P. R., Camfield, C., Cordon, K., & Dooley, J. M. (1994) · Developmental Medicine & Child Neurology · doi:10.1111/j.1469-8749.1994.tb11779.x · Cited by 146
On the incidence of fits and mental retardation in tuberous sclerosis.
Webb, D. W., Fryer, A. E., & Osborne, J. P. (1991) · Journal of Medical Genetics · doi:10.1136/jmg.28.6.395 · Cited by 145
Sturge–Weber syndrome
Arzimanoglou, A. A., Andermann, F., Aicardi, J. F., Sainte‐Rose, C., Beaulieu, M.-A., Villemure, J., Olivier, A., & Rasmussen, T. (2000) · Neurology · doi:10.1212/wnl.55.10.1472 · Cited by 142
Identification of Epilepsy Genes in Human and Mouse
Meisler, M. H., Kearney, J. A., Ottman, R., & Escayg, A. (2001) · Annual Review of Genetics · doi:10.1146/annurev.genet.35.102401.091142 · Cited by 138
Temporal lobe epilepsy in childhood: Clinical, EEG, and neuroimaging findings and syndrome classification in a cohort with new-onset seizures
Harvey, A. S., Berkovic, S. F., Wrennall, J. A., & Hopkins, I. J. (1997) · Neurology · doi:10.1212/wnl.49.4.960 · Cited by 137
Localization of subclinical ictal activity by functional magnetic resonance imaging: Correlation with invasive monitoring
Detre, J. A., Sirven, J. I., Alsop, D. C., O’Connor, M. J., & French, J. A. (1995) · Annals of Neurology · doi:10.1002/ana.410380410 · Cited by 136
Delineation of cryptogenic Lennox–Gastaut syndrome and myoclonic astatic epilepsy using multiple correspondence analysis
Kamińska, A., Ickowicz, A., Plouin, P., Bru, M., Dellatolas, G., & Dulac, O. (1999) · Epilepsy Research · doi:10.1016/s0920-1211(99)00021-2 · Cited by 133
Epileptic Nocturnal Wanderings
Plazzi, G., Tinuper, P., Montagna, P., Provini, F., & Lugaresi, E. (1995) · SLEEP · doi:10.1093/sleep/18.9.749 · Cited by 132
Advances in epileptology: XIth epilepsy international symposium
Hynie, S. (1982) · Neuropharmacology · doi:10.1016/0028-3908(82)90226-x · Cited by 132
Early versus late antiepileptic drug withdrawal for people with epilepsy in remission
Strozzi, I., Nevitt, S. J., Sperling, M. R., Wingerchuk, D. M., & Sirven, J. I. (2015) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd001902.pub2 · Cited by 130
Early‐Onset Benign Occipital Seizure Susceptibility Syndrome
Ferrie, C. D., Beaumanoir, A., Guerrini, R., Kivity, S., Vigevano, F., Takaishi, Y., Watanabe, K., Mira, L., Capizzi, G., Costa, P., et al. (1997) · Epilepsia · doi:10.1111/j.1528-1157.1997.tb01119.x · Cited by 130
Self-citation
Epilepsy in patients with cerebral palsy
Hadjipanayis, A., Hadjichristodoulou, C. S., & Youroukos, S. (1997) · Developmental Medicine & Child Neurology · doi:10.1111/j.1469-8749.1997.tb07359.x · Cited by 129
Autosomal dominant partial epilepsy with auditory features: Defining the phenotype
Winawer, M. R., Ottman, R., Hauser, W. A., & Pedley, T. A. (2000) · Neurology · doi:10.1212/wnl.54.11.2173 · Cited by 129
Proton magnetic resonance spectroscopy in children with temporal lobe epilepsy
Cross, J. H., Connelly, A., Jackson, G. D., Johnson, C. L., Neville, B. G. R., & Gadian, D. G. (1996) · Annals of Neurology · doi:10.1002/ana.410390116 · Cited by 129
Cognitive Impairment in New Cases of Epilepsy Randomly Assigned to Carbamazepine, Phenytoin and Sodium Valproate
Forsythe, I., Butler, R., Berg, I., & McGuire, R. J. (1991) · Developmental Medicine & Child Neurology · doi:10.1111/j.1469-8749.1991.tb14917.x · Cited by 129
Intracranial EEG versus flumazenil and glucose PET in children with extratemporal lobe epilepsy
Muzik, O., da Silva, E. A., Juhász, C., Chugani, D. C., Shah, J., Nagy, F. T., Canady, A. I., von Stockhausen, H.-M., Herholz, K., Gates, J. R., et al. (2000) · Neurology · doi:10.1212/wnl.54.1.171 · Cited by 128
Epilepsy and malformations of the cerebral cortex
Guerrini, R., Sicca, F., & Parmeggiani, L. (2003) · Epileptic Disorders · doi:10.1684/j.1950-6945.2003.tb00560.x · Cited by 128
Self-citation
Epilepsy in the Tropics: I. Epidemiology, Socioeconomic Risk Factors, and Etiology
Bittencourt, P. R. M., Adamolekum, B., Bharucha, N. E., Carpio, A., Cossío, O. H., Danesi, M. A., Dumas, M., Meinardi, H., Ordinario, A. T., Senanayake, N., et al. (1996) · Epilepsia · doi:10.1111/j.1528-1157.1996.tb01035.x · Cited by 127
A placebo-controlled trial of lamotrigine add-on therapy for partial seizures in children
DUCHOWNY, M. S., Pellock, J. M., Graf, W. D., Billard, C., Gilman, J. T., Casale, E. J., Womble, G. P., Risner, M. E., Manasco, P. K., & for the Lamictal Pediatric Partial Seizure Study Group (1999) · Neurology · doi:10.1212/wnl.53.8.1724 · Cited by 126
Status epilepticus in a population‐based cohort with childhood‐onset epilepsy in Finland
Sillanpää, M. L., & Shinnar, S. (2002) · Annals of Neurology · doi:10.1002/ana.10286 · Cited by 126
Efficacy and Mortality in Treatment of Refractory Generalized Convulsive Status Epilepticus in Children: A Meta-Analysis
Gilbert, D. L., Gartside, P. S., & Glauser, T. A. (1999) · Journal of Child Neurology · doi:10.1177/088307389901400909 · Cited by 126
Mosaic mutations of the LIS1 gene cause subcortical band heterotopia
Sicca, F., Kelemen, A., Genton, P., Das, S., Mei, D., Moro, F., Dobyns, W. B., & Guerrini, R. (2003) · Neurology · doi:10.1212/wnl.61.8.1042 · Cited by 126
Self-citation
Gabapentin Toxicity in Children Manifesting as Behavioral Changes
Wolf, S. M., Shinnar, S., Kang, H., Ballaban‐Gil, K. R., & Moshé, S. L. (1995) · Epilepsia · doi:10.1111/j.1528-1157.1995.tb01063.x · Cited by 124
The Efficacy of Lamotrigine in Children and Adolescents with Refractory Generalized Epilepsy: A Randomized, Double‐Blind, Crossover Study
Eriksson, A., Nergårdh, A., & Hoppu, K. (1998) · Epilepsia · doi:10.1111/j.1528-1157.1998.tb01411.x · Cited by 123
Landau–Kleffner syndrome (LKS): long-term follow-up and links with electrical status epilepticus during sleep (ESES)
Rossi, P. G., Parmeggiani, A., Posar, A., Scaduto, M. C., Chiodo, S., & Vatti, G. (1999) · Brain and Development · doi:10.1016/s0387-7604(98)00071-0 · Cited by 121
Comparative Study of Ethosuximide and Sodium Valproate in the Treatment of Typical Absence Seizures (Petit Mal)
Callaghan, N., O’Hare, J. A., O'Driscoll, D., O’Neill, B., & Daly, M. (1982) · Developmental Medicine & Child Neurology · doi:10.1111/j.1469-8749.1982.tb13703.x · Cited by 120
Febrile seizures and hippocampal sclerosis: Frequent and related findings in intractable temporal lobe epilepsy of childhood
Harvey, A. S., Grattan‐Smith, J. D., Desmond, P. M., Chow, C. W., & Berkovic, S. F. (1995) · Pediatric Neurology · doi:10.1016/0887-8994(95)00022-8 · Cited by 120
Adverse Reactions to New Anticonvulsant Drugs
Wong, I. C. K., & Lhatoo, S. D. (2000) · Drug Safety · doi:10.2165/00002018-200023010-00003 · Cited by 117
Reflex seizures and reflex epilepsies
Koutroumanidis, M., & Panayiotopoulos, C. (2004) · CRC Press eBooks · doi:10.1201/b13560-36 · Cited by 116
Language outcome following multiple subpial transection for LandauKleffner syndrome
Grote, C. L. (1999) · Brain · doi:10.1093/brain/122.3.561 · Cited by 116
Short‐Term Outcomes of Children with Febrile Status Epilepticus
Shinnar, S., Pellock, J. M., Berg, A. T., O’Dell, C., Driscoll, S. M., Maytal, J., Moshé, S. L., & DeLorenzo, R. J. (2001) · Epilepsia · doi:10.1046/j.1528-1157.2001.10000.x · Cited by 116
Comprehensive Epileptology
Henry, J. (1991) · Neurology · doi:10.1212/wnl.41.6.957-b · Cited by 116
Meningitis is a common cause of convulsive status epilepticus with fever
Chin, R. (2004) · Archives of Disease in Childhood · doi:10.1136/adc.2003.038844 · Cited by 115
Focal spike‐induced cerebral dysfunction is related to the after‐coming slow wave
Shewmon, D. A., & Erwin, R. J. (1988) · Annals of Neurology · doi:10.1002/ana.410230205 · Cited by 115
Elementary visual hallucinations in migraine and epilepsy.
Panayiotopoulos, C. P. (1994) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.57.11.1371 · Cited by 112
Epidemiological data of West syndrome in Finland
Riikonen, R. (2001) · Brain and Development · doi:10.1016/s0387-7604(01)00263-7 · Cited by 110
HEMIMEGALENCEPHALY: A CLINICOPATHOLOGICAL STUDY OF FOUR CASES
Robain, O., FLOQUET, C., Heldt, N., & Rozenberg, F. (1988) · Neuropathology and Applied Neurobiology · doi:10.1111/j.1365-2990.1988.tb00875.x · Cited by 109
Principles of Antiepileptic Drug Action
Rogawski, M. A. (2002) · Cited by 107
Infantile spasms
Wong, M. L., & Trevathan, E. (2001) · Pediatric Neurology · doi:10.1016/s0887-8994(00)00238-1 · Cited by 104
Surgery of epilepsy associated with focal lesions in childhood
Bourgeois, M., Sainte‐Rose, C., Lellouch‐Tubiana, A., Mallucci, C. L., Brunelle, F., Maixner, W. J., Cinalli, G., Pierre‐Kahn, A., Rénier, D., Zérah, M., et al. (1999) · Journal of neurosurgery · doi:10.3171/jns.1999.90.5.0833 · Cited by 102

Research works printed but not linked: 1

Erba, 1990, Sturge-Weber syndrome: Natural history and indications for surgery, J Epilepsy, 3, 287

Sorted by citations

Epilepsy: new advances
Moshé, S. L., Perucca, E., Ryvlin, P., & Tomson, T. (2014) · The Lancet · doi:10.1016/s0140-6736(14)60456-6 · Cited by 932
Chronic epilepsy and cognition
Elger, C. E., Helmstaedter, C., & Kurthen, M. (2004) · The Lancet Neurology · doi:10.1016/s1474-4422(04)00906-8 · Cited by 766
Outcomes of epilepsy surgery in adults and children
Spencer, S. S., & Huh, L. L. (2008) · The Lancet Neurology · doi:10.1016/s1474-4422(08)70109-1 · Cited by 768
Epilepsy in autism
Tuchman, R. F., & Rapin, I. (2002) · The Lancet Neurology · doi:10.1016/s1474-4422(02)00160-6 · Cited by 727
Characterization of ethosuximide reduction of low‐threshold calcium current in thalamic neurons
Coulter, D. A., Huguenard, J. R., & Prince, D. A. (1989) · Annals of Neurology · doi:10.1002/ana.410250610 · Cited by 508

See all 850

Authors: Guerrini, R.
Affiliations: University of Pisa (IT)
Corresponding author: Guerrini, Renzo
ORCID: Guerrini, Renzo
Venue: The Lancet
Publisher: Elsevier BV
Published: 2006-02
Volume: 367
Issue: 9509
Pages: 499-524
ISSN: 0099-5355 (ISSN-L)
0140-6736
DOI: 10.1016/s0140-6736(06)68182-8
OpenAlex: W2047243927
Cited by: 848
References: 321
Citations by year: 2026: 15 · 2025: 29 · 2024: 30 · 2023: 27 · 2022: 33 · 2021: 33 · 2020: 21 · 2019: 22 · 2018: 19 · 2017: 20 · 2016: 17 · 2015: 28 · 2014: 26 · 2013: 31 · 2012: 33
FWCI: 4.79
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: The Lancet (publishedVersion)
PubMed (publishedVersion)
Florence Research (University of Florence) (submittedVersion)
Topics: Health Sciences › Medicine › Clinical Neurology › Epilepsy research and treatment
Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Pharmacological Effects and Toxicity Studies
Health Sciences › Medicine › Physiology (medical) › Diet and metabolism studies
Keywords: pediatric epilepsy, epileptic encephalopathy, perinatal encephalopathy, cortical dysplasia, hippocampal sclerosis, ion channel disorders, benign rolandic epilepsy, antiepileptic drugs, epilepsy surgery, etiology, neuroimaging, EEG diagnosis, cognitive side effects
MeSH terms: Adolescent, Anticonvulsants, Child, Child, Preschool, Epilepsy, Humans, Infant, Infant, Newborn, Prognosis

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Epilepsy in children

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks