The DOI matches its Crossref record; 17 of the 18 references it cites were found in a registry or an index.
Effectiveness and impact of a reduced infant schedule of 4CMenB vaccine against group B meningococcal disease in England: a national observational cohort study
Abstract
Background In September, 2015, the UK became the first country to introduce the multicomponent group B meningococcal (MenB) vaccine (4CMenB, Bexsero) into a publicly funded national immunisation programme. A reduced two-dose priming schedule was offered to infants at 2 months and 4 months, alongside an opportunistic catch-up for 3 month and 4 month olds. 4CMenB was predicted to protect against 73-88% of MenB strains. We aimed to assess the effectiveness and impact of 4CMenB in vaccine-eligible infants in England.Methods Public Health England (PHE) undertakes enhanced surveillance of meningococcal disease through a combination of clinical, public health, and laboratory reporting. Laboratory-confirmed cases of meningococcal disease are followed up with PHE local health protection teams, general practitioners, and hospital clinicians to collect demographic data, vaccination history, clinical presentation, and outcome. For cases diagnosed between Sept 1, 2015, and June 30, 2016, vaccine effectiveness was assessed using the screening method. Impact was assessed by comparing numbers of cases of MenB in vaccine-eligible children to equivalent cohorts in the previous 4 years and to cases in vaccine-ineligible children.Findings Coverage of 4CMenB in infants eligible for routine vaccination was high, achieving 95·5% for one dose and 88·6% for two doses by 6 months of age. Two-dose vaccine effectiveness was 82·9% (95% CI 24·1-95·2) against all MenB cases, equivalent to a vaccine effectiveness of 94·2% against the highest predicted MenB strain coverage of 88%. Compared with the prevaccine period, there was a 50% incidence rate ratio (IRR) reduction in MenB cases in the vaccine-eligible cohort (37 cases vs average 74 cases; IRR 0·50 [95% CI 0·36-0·71]; p=0·0001), irrespective of the infants' vaccination status or predicted MenB strain coverage. Similar reductions were observed even after adjustment for disease trends in vaccine-eligible and vaccine-ineligible children.Interpretation The two-dose 4CMenB priming schedule was highly effective in preventing MenB disease in infants. Cases in vaccine-eligible infants halved in the first 10 months of the programme. While ongoing national surveillance will continue to monitor the longer-term impact of the programme, these findings represent a step forward in the battle against meningococcal disease and will help reassure that the vaccine protects against this deadly infection.Funding Public Health England.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“The vaccine is anticipated to protect against 73-88% of invasive strains, but ongoing surveillance will be essential to determine true vaccine effectiveness.16”
From Community-acquired acute bacterial meningitis in adults: a clinical update (2019) · cites this paper as [16]
Citations
Cites
Serruto, D., Bottomley, M. J., Ram, S., Giuliani, M. M., & Rappuoli, R. (2012) · Vaccine · doi:10.1016/j.vaccine.2012.01.033 · Cited by 405
Donnelly, J., Medini, D., Boccadifuoco, G., Biolchi, A., Ward, J. I., Frasch, C. E., Moxon, E. R., Stella, M., Comanducci, M., Bambini, S., et al. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1013758107 · Cited by 296
Vogel, U. F., Taha, M., Vázquez, J. A., Findlow, J., Claus, H., Stefanelli, P., Caugant, D. A., Kriz, P., Abad, R., Bambini, S., et al. (2013) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(13)70006-9 · Cited by 283
Self-citationEstimation of Vaccine Effectiveness Using the Screening Method
Farrington, P. (1993) · International Journal of Epidemiology · doi:10.1093/ije/22.4.742 · Cited by 261
Advances in the Development of Vaccines againstNeisseria meningitidis
Tan, L., Carlone, G. M., & Borrow, R. (2010) · New England Journal of Medicine · doi:10.1056/nejmra0906357 · Cited by 233
Self-citationCartwright, K. A. V., Morris, R., Rümke, H. C., Fox, A., Borrow, R., Begg, N. T., Richmond, P., & POOLMAN, J. T. (1999) · Vaccine · doi:10.1016/s0264-410x(99)00044-4 · Cited by 176
Self-citationMeningococcal C conjugate vaccine: the experience in England and Wales
Campbell, H., Borrow, R., Salisbury, D., & Miller, E. (2009) · Vaccine · doi:10.1016/j.vaccine.2009.04.067 · Cited by 168
Self-citationChristensen, H., Trotter, C. L., Hickman, M., & Edmunds, W. J. (2014) · BMJ · doi:10.1136/bmj.g5725 · Cited by 142
Frosi, G., Biolchi, A., Sapio, M. L., Rigat, F., Gilchrist, S., Lucidarme, J., Findlow, J., Borrow, R., Pizza, M., Giuliani, M. M., et al. (2013) · Vaccine · doi:10.1016/j.vaccine.2013.08.006 · Cited by 137
Self-citationVernikos, G. S., & Medini, D. (2014) · Pathogens and Global Health · doi:10.1179/2047773214y.0000000162 · Cited by 104
Cited by
Sorted by citations
Items 101–200 of 276
Humbert, M. V., & Christodoulides, M. (2018) · Vaccine · doi:10.1016/j.vaccine.2018.05.069 · Cited by 20
Mulhall, R., Bennett, D. E., Cunney, R., Borrow, R., Lucidarme, J., Findlow, J., Jolley, K. A., Bray, J. E., Maiden, M. C. J., Moschioni, M., et al. (2018) · mSphere · doi:10.1128/msphere.00196-18 · Cited by 20
Self-citationLorton, F., Chalumeau, M., Assathiany, R., Martinot, A., Bucchia, M., Roué, J., Bourgoin, P., Chantreuil, J., Boussicault, G., Gaillot, T., et al. (2018) · Paediatric and Perinatal Epidemiology · doi:10.1111/ppe.12500 · Cited by 20
The yin and yang of fever after meningococcal B vaccination
Ladhani, S. N., & Riordan, A. I. (2017) · Archives of Disease in Childhood · doi:10.1136/archdischild-2017-313419 · Cited by 19
Self-citationTaha, M., Gaudelus, J., Deghmane, A., & Caron, F. (2020) · Human Vaccines & Immunotherapeutics · doi:10.1080/21645515.2020.1729030 · Cited by 19
Immunisation schedule of the Spanish Association of Paediatrics: 2019 recommendations
Moreno‐Pérez, D., García, F. J. Á., Aldeán, J. Á., Ortega, M. J. C., Garcés‐Sánchez, M., Sánchez, N. G., Merino, Á. H., Hernández, M. J. M., Moína, M. M., Melián, A. M., et al. (2019) · Anales de Pediatría (English Edition) · doi:10.1016/j.anpede.2018.11.001 · Cited by 18
Meningococcal vaccines in China
Xu, Y., Li, Y., Wang, S., Li, M., Xu, M., & Ye, Q. (2021) · Human Vaccines & Immunotherapeutics · doi:10.1080/21645515.2020.1857201 · Cited by 18
Cardoso, G. P., Lagrée-Chastan, M., Caséris, M., Gaudelus, J., Haas, H., Leroy, J., Bakhache, P., Pujol, J.-F., Werner, A., Dommergues, M., et al. (2022) · Frontiers in Pediatrics · doi:10.3389/fped.2022.1000657 · Cited by 18
Mensah, A. A., Campbell, H. J., Clark, S. A., Ribeiro, S., Lucidarme, J., Bai, X., Borrow, R., & Ladhani, S. N. (2022) · The Lancet Child & Adolescent Health · doi:10.1016/s2352-4642(22)00379-0 · Cited by 18
Self-citationHarcourt, S., Morbey, R., Bates, C. J., Carter, H., Ladhani, S. N., de Lusignan, S., Smith, G., & Elliot, A. J. (2017) · Vaccine · doi:10.1016/j.vaccine.2017.11.076 · Cited by 18
Self-citationSafety of meningococcal group B vaccination in hospitalised premature infants
Kent, A., Beebeejaun, K., Braccio, S., Kadambari, S., Clarke, P., Heath, P. T., & Ladhani, S. N. (2018) · Archives of Disease in Childhood Fetal & Neonatal · doi:10.1136/archdischild-2017-314152 · Cited by 18
Self-citationSafety of meningococcal B vaccine (4CMenB) in adolescents in Australia
Marshall, H. S., KOEHLER, A. P., Wang, B., Ahoure, M., Gold, M., Quinn, H., Crawford, N. W., Pratt, N. L., Sullivan, T., & Macartney, K. K. (2020) · Vaccine · doi:10.1016/j.vaccine.2020.07.009 · Cited by 18
Awareness, Attitudes, and Practices Toward Meningococcal B Vaccine among Pediatricians in Italy
Ferrara, P., Stromillo, L., & Albano, L. (2018) · Medicina · doi:10.3390/medicina54060100 · Cited by 17
Bekkat-Berkani, R., Fragapane, E., Preiss, S., Rappuoli, R., Sohn, W.-Y., Soumahoro, L., & Vadivelu, K. (2022) · Journal of Infection · doi:10.1016/j.jinf.2022.09.001 · Cited by 17
Commentary: Estimation of vaccine effectiveness using the screening method
Flannery, B. L., Andrews, N. J., Feikin, D. R., & Patel, M. K. (2022) · International Journal of Epidemiology · doi:10.1093/ije/dyac013 · Cited by 17
Self-citationEmerging clinical experience with vaccines against group B meningococcal disease
Wilkins, A. L., & Snape, M. D. (2017) · Vaccine · doi:10.1016/j.vaccine.2017.07.056 · Cited by 16
van den Broek, B., van Els, C. A. C. M., Kuipers, B., van Aerde, K., Henriet, S., de Groot, R., de Jonge, M. I., Langereis, J. D., & van der Flier, M. (2019) · Clinical & Experimental Immunology · doi:10.1111/cei.13368 · Cited by 16
Carr, J., Plested, E. L., Aley, P. K., Camara, S., Davis, K., MacLennan, J. M., Gray, S. J., Faust, S. N., Borrow, R., Christensen, H., et al. (2020) · BMJ Open · doi:10.1136/bmjopen-2020-037358 · Cited by 16
Self-citationSadarangani, M., Sell, T., Iro, M. A., Snape, M. D., Voysey, M., Finn, A. H. R., Heath, P. T., Bona, G., Esposito, S., Díez‐Domingo, J., et al. (2017) · Canadian Medical Association Journal · doi:10.1503/cmaj.161288 · Cited by 16
Stawasz, A., Huang, L., Kirby, P., & Bloom, D. E. (2020) · Frontiers in Public Health · doi:10.3389/fpubh.2020.00261 · Cited by 16
Calendario de vacunaciones de la Asociación Española de Pediatría: recomendaciones 2020
García, F. J. Á., Ortega, M. J. C., Aldeán, J. Á., Garcés‐Sánchez, M., Sánchez, N. G., Llanos, E. G., Merino, Á. H., de Arce, A. I., Moína, M. M., Melián, A. M., et al. (2020) · Anales de Pediatría · doi:10.1016/j.anpedi.2019.10.007 · Cited by 16
Villena, R., Sáfadi, M. A. P., de Gentile, A. S., Pujadas, M., de la Maza, V., George, S., & Torres, J. P. (2023) · Vaccines · doi:10.3390/vaccines11121841 · Cited by 15
Wang, B., Giles, L. C., Andraweera, P. H., McMillan, M., Beazley, R., Sisnowski, J., Almond, S., Mitchell, J., Lally, N., Bell, C., et al. (2024) · Open Forum Infectious Diseases · doi:10.1093/ofid/ofae726 · Cited by 15
Biolchi, A., Tomei, S., Santini, L., Welsch, J. A., Toneatto, D., Gaitatzis, N., Bai, X., Borrow, R., Giuliani, M. M., Mori, E., et al. (2018) · Human Vaccines & Immunotherapeutics · doi:10.1080/21645515.2018.1537756 · Cited by 15
Self-citationTo LP or not to LP? Identifying the Etiology of Pediatric Meningitis
Mijović, H., & Sadarangani, M. (2019) · The Pediatric Infectious Disease Journal · doi:10.1097/inf.0000000000002313 · Cited by 15
O’Connor, D., Pinto, M. V., Sheerin, D., Tomić, A., Drury, R. E., Channon‐Wells, S., Galal, U., Dold, C., Robinson, H., Kerridge, S. A., et al. (2020) · Molecular Systems Biology · doi:10.15252/msb.20209888 · Cited by 15
The next chapter for group B meningococcal vaccines
Wang, N., & Pollard, A. J. (2017) · Critical Reviews in Microbiology · doi:10.1080/1040841x.2017.1329276 · Cited by 15
Inwald, D. P., Canter, R. R., Woolfall, K., O’Hara, C. B., Mouncey, P. R., Zenasni, Z., Hudson, N., Saunders, S., Carter, A., Jones, N., et al. (2018) · Health Technology Assessment · doi:10.3310/hta22510 · Cited by 15
A world without bacterial meningitis: how genomic epidemiology can inform vaccination strategy
Rodrigues, C. M. C., & Maiden, M. C. J. (2018) · F1000Research · doi:10.12688/f1000research.13793.1 · Cited by 15
Doaré, K. L., Gaylord, M. A., Anderson, A. S., Andrews, N. J., Baker, C. J., Bolcen, S. J., Felek, A., Giardina, P. C., Grube, C. D., Hall, T., et al. (2024) · Human Vaccines & Immunotherapeutics · doi:10.1080/21645515.2024.2330138 · Cited by 14
Self-citationChiu, N., Huang, L., Willemsen, A., Bhusal, C., Arora, A. K., Mojares, Z. R., & Toneatto, D. (2018) · Human Vaccines & Immunotherapeutics · doi:10.1080/21645515.2018.1425659 · Cited by 14
Meningococcal vaccination in pregnancy
Raya, B. A., & Sadarangani, M. (2018) · Human Vaccines & Immunotherapeutics · doi:10.1080/21645515.2018.1445447 · Cited by 14
Rodrigues, C. M. C., Chan, H., Vipond, C., Jolley, K. A., Harrison, O. B., Wheeler, J. X., Whiting, G. C., Feavers, I. M., & Maiden, M. C. J. (2018) · Wellcome Open Research · doi:10.12688/wellcomeopenres.14859.1 · Cited by 14
Parra, M. M., de Gentile, A. S., Narváez, J. A. V., Capdevila, A., Minguez, Á. R., Carrascal, M., Willemsen, A., Bhusal, C., & Toneatto, D. (2018) · Vaccine · doi:10.1016/j.vaccine.2018.10.096 · Cited by 15
Calendario de vacunaciones de la Asociación Española de Pediatría: recomendaciones 2019
Moreno‐Pérez, D., García, F. J. Á., Aldeán, J. Á., Ortega, M. J. C., Garcés‐Sánchez, M., Sánchez, N. G., Merino, Á. H., Hernández, M. J. M., Moína, M. M., Melián, A. M., et al. (2019) · Anales de Pediatría · doi:10.1016/j.anpedi.2018.10.006 · Cited by 14
IMMUNISATION SCHEDULE OF THE SPANISH ASSOCIATION OF PAEDIATRICS: 2020 RECOMMENDATIONS
García, F. J. Á., Ortega, M. J. C., Aldeán, J. Á., Garcés‐Sánchez, M., Sánchez, N. G., Llanos, E. G., Merino, Á. H., de Arce, A. I., Moína, M. M., Melián, A. M., et al. (2020) · Anales de Pediatría (English Edition) · doi:10.1016/j.anpede.2019.10.003 · Cited by 13
Impact and effectiveness of meningococcal vaccines: a review
de Oliveira, L. H., Jaúregui, B., Carvalho, A. F., & Giglio, N. (2017) · Revista Panamericana de Salud Pública · doi:10.26633/rpsp.2017.158 · Cited by 13
Unraveling Neisseria meningitidis pathogenesis: from functional genomics to experimental models
Soriani, M. (2017) · F1000Research · doi:10.12688/f1000research.11279.1 · Cited by 13
Terranova, L., Principi, N., Bianchini, S., Pietro, G. M. D., Umbrello, G., Madini, B., & Esposito, S. (2018) · Human Vaccines & Immunotherapeutics · doi:10.1080/21645515.2018.1450121 · Cited by 13
Drozd-Dąbrowska, M., Topczewska, K., Korzeń, M., Sałacka, A., & Gańczak, M. (2019) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph16020265 · Cited by 13
Alderfer, J., Srivastava, A. K., Istúriz, R., Burman, C., Absalon, J., Beeslaar, J. F., & Perez, J. L. (2019) · Human Vaccines & Immunotherapeutics · doi:10.1080/21645515.2019.1581542 · Cited by 13
Sheerin, D., O’Connor, D., Dold, C., Clutterbuck, E., Attar, M., Rollier, C. S., Sadarangani, M., & Pollard, A. J. (2019) · Scientific Reports · doi:10.1038/s41598-019-50310-0 · Cited by 13
Marshall, H. S., Andraweera, P. H., Wang, B., McMillan, M., Koehler, A. P., Lally, N., Almond, S., Denehy, E., Ahoure, M., Giles, L. C., et al. (2021) · Human Vaccines & Immunotherapeutics · doi:10.1080/21645515.2020.1827614 · Cited by 13
Community-acquired acute bacterial meningitis in adults: a clinical update
Ellis, J., Luintel, A., Chandna, A., & Heyderman, R. S. (2019) · British Medical Bulletin · doi:10.1093/bmb/ldz023 · Cited by 12
Croucher, N. J. (2024) · Microbial Biotechnology · doi:10.1111/1751-7915.14446 · Cited by 12
4CMenB vaccine effectiveness: reasons for optimism
Basta, N. E., & Christensen, H. (2016) · The Lancet · doi:10.1016/s0140-6736(16)32061-x · Cited by 12
Watson, P. S., Novy, P., & Friedland, L. R. (2019) · International Journal of Infectious Diseases · doi:10.1016/j.ijid.2019.05.019 · Cited by 12
Meningococcal vaccines in Australia: a 2019 update
Sharma, K., Chiu, C., & Wood, N. (2019) · Australian Prescriber · doi:10.18773/austprescr.2019.042 · Cited by 12
Argante, L., Abbing‐Karahagopian, V., Vadivelu, K., Rappuoli, R., & Medini, D. (2021) · BMC Infectious Diseases · doi:10.1186/s12879-021-06906-x · Cited by 12
Zografaki, I., Detsis, M., del Amo, M., Iantomasi, R., Maia, A., Montuori, E. A., & Méndez, C. (2023) · Expert Review of Vaccines · doi:10.1080/14760584.2023.2225596 · Cited by 12
Watson, P. S., Novy, P., Bekkat-Berkani, R., Strubbe, F., & Banzhoff, A. (2019) · Expert Review of Vaccines · doi:10.1080/14760584.2019.1580579 · Cited by 12
Chang, H.-Y., Vuong, J. T., Hu, F., Liberator, P., Chen, A., Kretz, C. B., Blain, A. E., Li, H., Retchless, A. C., Whaley, M. J., et al. (2019) · Journal of Infection · doi:10.1016/j.jinf.2019.09.001 · Cited by 12
Epidemiology and Control of Meningococcal Disease in Canada: A Long, Complex, and Unfinished Story
Wals, P. D. (2019) · Canadian Journal of Infectious Diseases and Medical Microbiology · doi:10.1155/2019/8901847 · Cited by 12
Breton, M.-C., Huang, L., Snedecor, S. J., Cornelio, N., & Fanton-Aita, F. (2020) · Canadian Journal of Public Health · doi:10.17269/s41997-019-00275-4 · Cited by 11
de Lemos, A. P. S., Sacchi, C. T., Gonçalves, C. R., Camargo, C. H., & Andrade, A. L. (2020) · PLoS ONE · doi:10.1371/journal.pone.0243375 · Cited by 11
Clark, S. A., Lucidarme, J., Angel, G., Lekshmi, A., Morales‐Aza, B. M., Willerton, L., Campbell, H. J., Gray, S. J., Ladhani, S. N., Wade, M., et al. (2019) · Scientific Reports · doi:10.1038/s41598-019-46483-3 · Cited by 11
Self-citationEvaluación económica de la inclusión en el calendario vacunal de 4CMenB (Bexsero®) en España
Ruiz-Montero, R., Epstein, D. M., Guzmán-Herrador, B., & Espín, J. (2019) · Gaceta Sanitaria · doi:10.1016/j.gaceta.2019.08.007 · Cited by 11
Bodini, M., Brozzi, A., Giuliani, M., Nohynek, H., Vainio, A., Kuusi, M., Paola, R. D., Pizza, M., Medini, D., Toropainen, M., et al. (2020) · mSphere · doi:10.1128/msphere.00376-20 · Cited by 11
Vesikari, T., Brzostek, J., Ahonen, A., Paassilta, M., Majda-Stanisławska, E., Szenborn, L., Virta, M., Clifford, R. A., Jackowska, T., Kimmel, M. A., et al. (2021) · Human Vaccines & Immunotherapeutics · doi:10.1080/21645515.2021.1968214 · Cited by 11
Lian, S., Liu, J., Yang, Y., Zhu, G., & Xia, P. (2025) · Virulence · doi:10.1080/21505594.2025.2553781 · Cited by 10
Meningococcal arthritis and myopericarditis: a case report
Steele, L., Bechman, K., de Barra, E., & Mackworth-Young, C. G. (2017) · BMC Infectious Diseases · doi:10.1186/s12879-017-2845-3 · Cited by 10
Pittet, L. F., Abbas, M., Siegrist, C., & Pittet, D. (2019) · Intensive Care Medicine · doi:10.1007/s00134-019-05862-0 · Cited by 11
Chicuto, L. A. D., de Moraes, C., de Moraes, J. C., & Sáfadi, M. A. P. (2020) · Human Vaccines & Immunotherapeutics · doi:10.1080/21645515.2019.1700710 · Cited by 10
Meningococcal Capsular Group B Vaccines
Granoff, D. M., Pollard, A. J., & Harrison, L. H. (2017) · Elsevier eBooks · doi:10.1016/b978-0-323-35761-6.00053-5 · Cited by 10
Canalejo-Marco, G., Arruebo, M., & Sebastián, V. (2025) · Colloids and Surfaces B Biointerfaces · doi:10.1016/j.colsurfb.2025.115235 · Cited by 10
Dubus, M., Ladhani, S. N., & Vasu, V. (2019) · The Pediatric Infectious Disease Journal · doi:10.1097/inf.0000000000002507 · Cited by 9
Self-citationSilveira, M. M., McBride, A. J. A., & Trotter, C. L. (2019) · Vaccine · doi:10.1016/j.vaccine.2019.09.062 · Cited by 9
Stella, M., Giuliani, M., Biolchi, A., Tomei, S., Paola, R. D., Bai, X., Borrow, R., Lucidarme, J., Gaetana, R. L., Toneatto, D., et al. (2019) · Human Vaccines & Immunotherapeutics · doi:10.1080/21645515.2019.1688039 · Cited by 9
Self-citationLéo, S., Lazarević, V., Girard, M., Velasco, G. C. G.-J., Gaïa, N., Renzi, G., Cherkaoui, A., Hong, E., Taha, M., & Schrenzel, J. (2020) · Vaccine · doi:10.1016/j.vaccine.2020.05.071 · Cited by 9
Good News and Bad News — 4CMenB Vaccine for Group B Neisseria meningitidis
Harrison, L. H., & Stephens, D. S. (2020) · New England Journal of Medicine · doi:10.1056/nejme1916440 · Cited by 9
Rollier, C. S., Dold, C., Blackwell, L., Linder, A., Silva-Reyes, L., Clutterbuck, E., Davis, K., Ford, K. J., Liu, X., Holland, A., et al. (2022) · Vaccine · doi:10.1016/j.vaccine.2022.04.085 · Cited by 8
Self-citationGrowing evidence supports 4CMenB effectiveness
Ladhani, S. N., Borrow, R., & Andrews, N. J. (2018) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(18)30051-3 · Cited by 8
Self-citationBidmos, F. A., Nadel, S., Screaton, G. R., Kroll, J. S., & Langford, P. R. (2018) · Frontiers in Immunology · doi:10.3389/fimmu.2018.01621 · Cited by 8
Gbesemete, D. F., Laver, J. R., de Graaf, H., Ibrahim, M., Vaughan, A., Faust, S. N., GORRINGE, A. R., & Read, R. C. (2019) · BMJ Open · doi:10.1136/bmjopen-2018-026544 · Cited by 8
Bianchi, F., Veggi, D., Santini, L., Buricchi, F., Bartolini, E., Surdo, P. L., Martinelli, M., Finco, O., Masignani, V., Bottomley, M. J., et al. (2019) · The FASEB Journal · doi:10.1096/fj.201900374r · Cited by 8
Meningococcal Serogroup B Disease in Vaccinated Children
Soler‐Garcia, A., de Sevilla, M. F., Abad, R., Esteva, C., Alsina, L., Vázquez, J. A., Muñoz‐Almagro, C., & Noguera‐Julián, A. (2019) · Journal of the Pediatric Infectious Diseases Society · doi:10.1093/jpids/piz071 · Cited by 8
Cinconze, E., Rosillon, D., Rappuoli, R., Vadivelu, K., Bekkat-Berkani, R., & Abbing‐Karahagopian, V. (2023) · Vaccine · doi:10.1016/j.vaccine.2023.05.025 · Cited by 7
Manoharan, S., Farman, T. A., Piliou, S., & Mastroeni, P. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1473064 · Cited by 7
Pinto, M. V., O’Connor, D., Galal, U., Clutterbuck, E., Robinson, H., Plested, E. L., Bibi, S., Camara, S., Hughes, H., Kerridge, S. A., et al. (2020) · Open Forum Infectious Diseases · doi:10.1093/ofid/ofaa143 · Cited by 7
Self-citationGlobal Epidemiology of Vaccine-preventable Bacterial Meningitis
Syrogiannopoulos, G. A., Michoula, A. N., & Grivea, I. N. (2022) · The Pediatric Infectious Disease Journal · doi:10.1097/inf.0000000000003629 · Cited by 7
Protecting UK adolescents and adults against meningococcal serogroup B disease
Vyse, A., Ellsbury, G., & Madhava, H. (2018) · Expert Review of Vaccines · doi:10.1080/14760584.2018.1432360 · Cited by 7
Two centuries of immunisation in the UK (part 1)
Lang, S., Loving, S., McCarthy, N. D., Ramsay, M. E., SALISBURY, D. M., & Pollard, A. J. (2019) · Archives of Disease in Childhood · doi:10.1136/archdischild-2019-317314 · Cited by 7
Self-citationMeningitis vaccines in children: what have we achieved and where next?
McAlpine, A., & Sadarangani, M. (2019) · Current Opinion in Infectious Diseases · doi:10.1097/qco.0000000000000580 · Cited by 7
The epidemiology of invasive meningococcal disease and the utility of vaccination in Malta
Pace, D., Gauci, C., & Barbara, C. (2020) · European Journal of Clinical Microbiology & Infectious Diseases · doi:10.1007/s10096-020-03914-8 · Cited by 7
Translating meningococcal serogroup B vaccines for healthcare professionals
Sáfadi, M. A. P., Martinón‐Torres, F., Serra, L., Burman, C., & Presa, J. V. (2021) · Expert Review of Vaccines · doi:10.1080/14760584.2021.1899820 · Cited by 7
Two centuries of immunisation in the UK (part II)
Lang, S., Loving, S., McCarthy, N. D., Ramsay, M. E., SALISBURY, D. M., & Pollard, A. J. (2019) · Archives of Disease in Childhood · doi:10.1136/archdischild-2019-317707 · Cited by 7
Self-citationCalendario de vacunaciones de la Asociación Española de Pediatría (CAV-AEP): recomendaciones 2018
Moreno‐Pérez, D., García, F. J. Á., Aldeán, J. Á., Ortega, M. J. C., Garcés‐Sánchez, M., Sánchez, N. G., Merino, Á. H., Hernández, M. J. M., Moína, M. M., Melián, A. M., et al. (2018) · Anales de Pediatría · doi:10.1016/j.anpedi.2017.10.001 · Cited by 7
Risk of Invasive Meningococcal Disease in Preterm Infants
Calvert, A., Campbell, H. J., Heath, P. T., Jones, C. E., Doaré, K. L., Mensah, A. A., & Ladhani, S. N. (2024) · Open Forum Infectious Diseases · doi:10.1093/ofid/ofae164 · Cited by 6
Self-citationBacterial extracellular vesicles as bioactive nanocarriers for wound treatment
Shi, Y., Zheng, Z., Li, Y., Wang, Y., Azevedo, H. S., Liu, X., Zhang, C., & Hu, H. (2026) · Acta Pharmaceutica Sinica B · doi:10.1016/j.apsb.2026.01.007 · Cited by 6
Optimal use of meningococcal serogroup B vaccines: moving beyond outbreak control
Balmer, P., & York, L. J. (2018) · Therapeutic Advances in Vaccines and Immunotherapy · doi:10.1177/2515135518781757 · Cited by 6
Blood biomarkers in early bacterial infection and sepsis diagnostics in feverish young children
Dagys, A., Laucaitytė, G., Volkevičiūtė, A., Abramavičius, S., Kėvalas, R., Vitkauskienė, A., & Jankauskaitė, L. (2022) · International Journal of Medical Sciences · doi:10.7150/ijms.69859 · Cited by 6
Nigeria introduces the world’s first Men5 CV meningitis vaccine
Aderinto, N., Olatunji, G. D., Kokori, E., Ogieuhi, I. J., Alao, A. E., Ajimotokan, O. I., Okam, O. V., Akinruli, O. A., & Olawoyin, M. T. (2025) · Discover Public Health · doi:10.1186/s12982-025-00592-9 · Cited by 5
Bettencourt, C. R., Nogueira, P., Gomes, J. P., & Simões, M. J. (2022) · Vaccine · doi:10.1016/j.vaccine.2022.06.038 · Cited by 5
Immunisation schedule of the Spanish Association of Paediatrics: 2018 recommendations
Moreno‐Pérez, D., García, F. J. Á., Aldeán, J. Á., Ortega, M. J. C., Garcés‐Sánchez, M., Sánchez, N. G., Merino, Á. H., Hernández, M. J. M., Moína, M. M., Melián, A. M., et al. (2018) · Anales de Pediatría (English Edition) · doi:10.1016/j.anpede.2017.11.001 · Cited by 5
Findlow, J., & Borrow, R. (2017) · Pathogens and Disease · doi:10.1093/femspd/ftx025 · Cited by 5
Self-citationCostoya, L., Marzoa, J., Ferreirós, C. M., & Criado, M. T. (2017) · Apmis · doi:10.1111/apm.12709 · Cited by 5
Meningococcal B Vaccines as a Paradigm of Safe and Effective Vaccines for Children
Tome, M. G., Gonzalez‐Quevedo, R., dos Santos, M. E., Dornbusch, H. J., Straus, S. M. J. M., & Cooke, E. (2025) · Vaccines · doi:10.3390/vaccines13070770 · Cited by 4
Bacterial Extracellular Vesicles in Biomedical Research and Clinical Translation
Arce‐Rodríguez, A., Noya, J. D. L. P., & Acuña, J. M. B. (2026) · Microbial Biotechnology · doi:10.1111/1751-7915.70350 · Cited by 4
La enfermedad meningocócica y las vacunas: algunas respuestas y todavía muchas preguntas
Godoy, P., Castilla, J., Astray, J., Tuells, J., Barrabeig, I., & Domı́nguez, Á. (2019) · Gaceta Sanitaria · doi:10.1016/j.gaceta.2019.09.004 · Cited by 4
Vaccination in old age: Challenges and promises
Caruso, C., Aiello, A., Pawelec, G., & Ligotti, M. E. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-822569-1.00020-2 · Cited by 4
Metadata
- Authors
- Parikh, S. R., Andrews, N. J., Beebeejaun, K., Campbell, H., Ribeiro, S., Ward, C., White, J. M., Borrow, R., Ramsay, M. E., & Ladhani, S. N.
- Affiliations
- Public Health England (GB)
- Corresponding author
- Ladhani, Shamez N
- ORCID
- Venue
- The Lancet
- Publisher
- Elsevier BV
- Published
- 2016-12
- Volume
- 388
- Issue
- 10061
- Pages
- 2775-2782
- ISSN
- 0099-5355 (ISSN-L)
- 0140-6736
- OpenAlex
- W2540474236
- Cited by
- 275
- References
- 18
- Citations by year
- 2026: 10 · 2025: 11 · 2024: 14 · 2023: 14 · 2022: 15 · 2021: 20 · 2020: 38 · 2019: 63 · 2018: 53 · 2017: 35 · 2016: 1
- FWCI
- 51.87
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The Lancet (publishedVersion)
- PubMed (publishedVersion)
- St George's Online Research Archive (St George's University of London) (acceptedVersion)
- Funders
- Public Health England
- Topics
- Life Sciences › Immunology and Microbiology › Microbiology › Bacterial Infections and Vaccines
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Neonatal and Maternal Infections
- Life Sciences › Immunology and Microbiology › Microbiology › Microbial infections and disease research
- Keywords
- 4CMenB, infant vaccination schedule, catch-up vaccination, meningococcal disease incidence, vaccination coverage, meningococcal serogroups, national vaccination program, disease surveillance, vaccine impact, meningococcal serogroup B
- MeSH terms
- United Kingdom, Humans, Immunization Schedule, Infant, Meningococcal Infections, Public Health, Treatment Outcome, Immunization Programs, Meningococcal Vaccines
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review