The DOI matches its Crossref record; 25 of the 26 references it cites were found in a registry or an index.
First-line ceritinib versus platinum-based chemotherapy in advanced ALK -rearranged non-small-cell lung cancer (ASCEND-4): a randomised, open-label, phase 3 study
Abstract
Background The efficacy of ceritinib in patients with untreated anaplastic lymphoma kinase (ALK)-rearranged non-small-cell lung cancer (NSCLC) is not known. We assessed the efficacy and safety of ceritinib versus platinum-based chemotherapy in these patients. Methods This randomised, open-label, phase 3 study in untreated patients with stage IIIB/IV ALK-rearranged non-squamous NSCLC was done in 134 centres across 28 countries. Eligible patients were assigned via interactive response technology to oral ceritinib 750 mg/day or platinum-based chemotherapy ([cisplatin 75 mg/m 2 or carboplatin AUC 5-6 plus pemetrexed 500 mg/m 2 ] every 3 weeks for four cycles followed by maintenance pemetrexed); randomisation was stratified by World Health Organization performance status (0 vs 1-2), previous neoadjuvant or adjuvant chemotherapy, and presence of brain metastases as per investigator's assessment at screening. Investigators and patients were not masked to treatment assignment. The primary endpoint was blinded independent review committee assessed progression-free survival, based on all randomly assigned patients (the full analysis set). Efficacy analyses were done based on the full analysis set. All safety analyses were done based on the safety set, which included all patients who received at least one dose of study drug. This trial is registered with ClinicalTrials.gov, number NCT01828099. Findings Between Aug 19, 2013, and May 11, 2015, 376 patients were randomly assigned to ceriti…
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Even more variable are duration of response to targeted therapy, progression-free survival and overall survival16–26, 28–32, 35.”
From Co-occurring genomic alterations in non-small-cell lung cancer biology and therapy (2019) · cites this paper as [25]
Citations
Cites
Identification of the transforming EML4–ALK fusion gene in non-small-cell lung cancer
Soda, M., Choi, Y. L., Enomoto, M., Takada, S., Yamashita, Y., Ishikawa, S., Fujiwara, S.-I., Watanabe, H., Kurashina, K., Hatanaka, H., et al. (2007) · Nature · doi:10.1038/nature05945 · Cited by 5,439
Scagliotti, G. V., Parikh, P., von Pawel, J., Biesma, B., Vansteenkiste, J., Manegold, C., Serwatowski, P., Gatzemeier, U., Digumarti, R., Zukin, M., et al. (2008) · Journal of Clinical Oncology · doi:10.1200/jco.2007.15.0375 · Cited by 3,203
First-Line Crizotinib versus Chemotherapy in ALK -Positive Lung Cancer
Solomon, B. J., Mok, T., Kim, D.-W., Wu, Y.-L., Nakagawa, K., Mekhail, T., Felip, E., Cappuzzo, F., Paolini, J., Usari, T., et al. (2014) · New England Journal of Medicine · doi:10.1056/nejmoa1408440 · Cited by 3,190
Self-citationClinical Features and Outcome of Patients With Non–Small-Cell Lung Cancer Who Harbor EML4-ALK
Shaw, A. T., Yeap, B. Y., Mino-Kenudson, M. A., Digumarthy, S. R., Costa, D. B., Heist, R. S., Solomon, B., Stubbs, H., Admane, S., McDermott, U., et al. (2009) · Journal of Clinical Oncology · doi:10.1200/jco.2009.22.6993 · Cited by 1,873
Ceritinib in ALK -Rearranged Non–Small-Cell Lung Cancer
Shaw, A. T., Kim, D.-W., Mehra, R., Tan, D. S. W., Felip, E., Chow, L. Q. M., Camidge, D. R., Vansteenkiste, J., Sharma, S., De Pas, T., et al. (2014) · New England Journal of Medicine · doi:10.1056/nejmoa1311107 · Cited by 1,495
Self-citationMechanisms of Acquired Crizotinib Resistance in ALK-Rearranged Lung Cancers
Katayama, R., Shaw, A. T., Khan, T. M., Mino-Kenudson, M. A., Solomon, B., Halmos, B., Jessop, N. A., Wain, J. C., Yeo, A. T., Benes, C. H., et al. (2012) · Science Translational Medicine · doi:10.1126/scitranslmed.3003316 · Cited by 1,337
Ciuleanu, T., Brodowicz, T., Zielinski, C., Kim, J. H., Krzakowski, M., Laack, E., Wu, Y.-L., Bover, I., Begbie, S., Tzekova, V., et al. (2009) · The Lancet · doi:10.1016/s0140-6736(09)61497-5 · Cited by 1,111
Self-citationHida, T., Nokihara, H., Kondo, M., Kim, Y. H., Azuma, K., Seto, T., Takiguchi, Y., Nishio, M., Yoshioka, H., Imamura, F., et al. (2017) · The Lancet · doi:10.1016/s0140-6736(17)30565-2 · Cited by 935
The ALK Inhibitor Ceritinib Overcomes Crizotinib Resistance in Non–Small Cell Lung Cancer
Friboulet, L., Li, N., Katayama, R., Lee, C. C., Gainor, J. F., Crystal, A., Michellys, P., Awad, M. M., Yanagitani, N., Kim, S., et al. (2014) · Cancer Discovery · doi:10.1158/2159-8290.cd-13-0846 · Cited by 867
Paz-Ares, L. G., de Marinis, F., Dediu, M., Thomas, M., Pujol, J.-L., Bidoli, P., Molinier, O., Sahoo, T. P., Laack, E., Reck, M., et al. (2013) · Journal of Clinical Oncology · doi:10.1200/jco.2012.47.1102 · Cited by 624
Self-citation
Cited by
Sorted by citations
Items 701–800 of 1,000
Gadgeel, S. M. (2018) · Future Oncology · doi:10.2217/fon-2018-0027 · Cited by 6
Sakamoto, H., Yanagitani, N., Manabe, R., Tsugitomi, R., Ogusu, S., Tozuka, T., Yoshida, H., Amino, Y., Ariyasu, R., Uchibori, K., et al. (2021) · Cancer Reports · doi:10.1002/cnr2.1414 · Cited by 6
Rao, S. S., Gahlot, U. S., Dulawat, S. S., Vyas, R., Ameta, K. L., & Verma, B. L. (2003) · Afinidad · Cited by 6
Fujibayashi, Y., Tane, S., Kitazume, M., Kuroda, S., Kimura, K., Kitamura, Y., & Nishio, W. (2022) · Thoracic Cancer · doi:10.1111/1759-7714.14365 · Cited by 6
Reckamp, K. L., Lin, H. M., Cranmer, H., Wu, Y., Zhang, P., Walton, L., Kay, S., Cichewicz, A. B., Neupane, B., Fahrbach, K. R., et al. (2022) · Future Oncology · doi:10.2217/fon-2022-0194 · Cited by 6
Self-citationChayab, L., Konstantelos, N., Leighl, N. B., Tadrous, M., & Wong, W. W. L. (2023) · PharmacoEconomics · doi:10.1007/s40273-023-01279-2 · Cited by 6
Development and Validation of txSim: A Model of Advanced Lung Cancer Treatment in Australia
Ngo, P., Karikios, D. J., Goldsbury, D. E., Wade, S. L., Lwin, Z., Hughes, B. G. M., Fong, K. M., Canfell, K., & Weber, M. F. (2023) · PharmacoEconomics · doi:10.1007/s40273-023-01291-6 · Cited by 6
Shih, J., Luo, Y., Chang, G., Chang, J. W., Wang, C.-C., Yang, T., Fang, W., & Shau, W. (2024) · Journal of the Formosan Medical Association · doi:10.1016/j.jfma.2023.12.019 · Cited by 6
Navigating resistance to ALK inhibitors in the lorlatinib era: a comprehensive perspective on NSCLC
Gemelli, M. T., Albini, A., Catalano, G., Incarbone, M., Cannone, M., Balladore, E., Ricotta, R., & Pelosi, G. (2024) · Expert Review of Anticancer Therapy · doi:10.1080/14737140.2024.2344648 · Cited by 6
Future Genetic/Genomic Biomarker Testing in Non–Small Cell Lung Cancer
Planchard, D., Remón, J., Nowak, F., & Soria, J. (2017) · American Society of Clinical Oncology Educational Book · doi:10.1200/edbk_100007 · Cited by 6
Self-citationAlectinib for advancedALK-positive non-small-cell lung cancer
Ly, A. C., Olin, J. L., & Smith, M. B. (2018) · American Journal of Health-System Pharmacy · doi:10.2146/ajhp170266 · Cited by 7
The Brigatinib Experience: A New Generation of Therapy for ALK-Positive Non-Small-Cell Lung Cancer
Amanam, I. U., Gupta, R., Mambetsariev, I., & Salgia, R. (2018) · Future Oncology · doi:10.2217/fon-2017-0545 · Cited by 6
Itchins, M., Hayes, S. A., Gill, A. J., Cooper, W. A., O’Connell, R. L., Howell, V. M., Clarke, S. J., & Pavlakis, N. (2018) · Asia-Pacific Journal of Clinical Oncology · doi:10.1111/ajco.12877 · Cited by 6
Hamard, C., Mignard, X., Pécuchet, N., Mathiot, N., Blons, H., Laurent‐Puig, P., Leroy, K., Mansuet‐Lupo, A., Chapron, J., Giraud, F., et al. (2018) · Revue de Pneumologie Clinique · doi:10.1016/j.pneumo.2018.09.013 · Cited by 6
Song, P., Zhang, X., Yang, D., Wang, H., Si, X., & Zhang, L. (2020) · Thoracic Cancer · doi:10.1111/1759-7714.13376 · Cited by 6
ALK Inhibitors in ALK-positive NSCLC with Central Nervous System Metastases
Aldea, M. D., Besse, B., & Hendriks, L. E. L. (2020) · European Oncology & Haematology · doi:10.17925/eoh.2020.16.1.18 · Cited by 6
Zhai, X., Wu, Q., Pu, D., Yin, L., Wang, W., Zhu, D., & Xu, F. (2022) · Frontiers in Oncology · doi:10.3389/fonc.2021.782682 · Cited by 6
Martinez‐García, M., Servitja, S., Quintela, N. V., Fernández, A. A., Jaime, A. B., de Ibargüen, B. C. S., Barco, S. D., Campelo, R. G., Sarrió, R. G., & Sepúlveda-Sánchez, J. M. (2022) · Clinical & Translational Oncology · doi:10.1007/s12094-022-02803-0 · Cited by 6
Self-citationTreatment Sequencing Strategies in Lung Cancer.
Pozza, D. H., & de Mello, R. A. (2022) · PubMed · doi:10.3779/j.issn.1009-3419.2022.104.01 · Cited by 7
Grenda, A., Jarosz, B., Krawczyk, P. A., Kucharczyk, T., Wojas‐Krawczyk, K., Reszka, K., Krukowska, K., Nicoś, M., Pankowski, J., Bryl, M., et al. (2018) · Journal of Thoracic Disease · doi:10.21037/jtd.2018.07.28 · Cited by 6
Huang, Y., Chow, K. K. H., Aredo, J. V., Padda, S. K., Han, S. S., Kakusa, B. W., & Gephart, M. H. (2019) · World Neurosurgery · doi:10.1016/j.wneu.2019.01.112 · Cited by 6
First-line management of metastatic non-small cell lung cancer: An Indian perspective
Ghadyalpatil, N. S., Pandey, A., Krishnamani, I., Srinivas, C., Rafiq, S. J., Hingmire, S., Maturu, V. N., Reddy, R., Kumar, K., Sreekanth, K., et al. (2019) · South Asian Journal of Cancer · doi:10.4103/sajc.sajc_294_18 · Cited by 6
Systemic Therapy for Mutation-Driven NSCLC
Sun, L., Marmarelis, M. E., & Langer, C. J. (2021) · Seminars in Radiation Oncology · doi:10.1016/j.semradonc.2020.11.011 · Cited by 6
Blind Identification Of Non-Minimum Phase Systems Using The Mean Differential Cepstrum
Amont, J., Danière, J., & Guilleî, F. (2015) · INFM-OAR (INFN Catania) · doi:10.5281/zenodo.37458 · Cited by 6
Lung cancer in India: The rewards of REWERDS (REal World Evidence from Retrospective Data analysiS)
Singh, N. (2020) · Current Problems in Cancer · doi:10.1016/j.currproblcancer.2020.100591 · Cited by 6
Grubb, W., Machtay, M. X., Dowlati, A., & Biswas, T. (2019) · Practical Radiation Oncology · doi:10.1016/j.prro.2018.11.002 · Cited by 5
Song, G., Li, Y., Kong, W., & Hu, G. (2023) · Frontiers in Oncology · doi:10.3389/fonc.2023.1235679 · Cited by 5
Chung, C., & Umoru, G. (2024) · Journal of Oncology Pharmacy Practice · doi:10.1177/10781552241242684 · Cited by 5
Utsumi, T., Mizuta, H., Seto, Y., Uchibori, K., Nishio, M., Okamoto, I., & Katayama, R. (2025) · Cancer Science · doi:10.1111/cas.70006 · Cited by 7
Advances of dual inhibitors based on ALK for the treatment of cancer
Chen, J., Guo, S., He, B., Zheng, W., Jiang, W., Yuan, Z., Xiang, Y., Peng, C., Wei, X., & Shi, J. (2025) · Bioorganic Chemistry · doi:10.1016/j.bioorg.2025.108417 · Cited by 5
Kyriacou, N. M., Gross, A. S., & McLachlan, A. J. (2025) · Clinical and Translational Science · doi:10.1111/cts.70224 · Cited by 5
Clinically-meaningful improvements in therapy for unresectable NSCLC
Katakura, S., & Murakami, S. (2022) · Expert Review of Anticancer Therapy · doi:10.1080/14737140.2022.2102483 · Cited by 5
Zou, Z., Gu, Y., Liang, L., Hao, X., Fan, C., Xin, T., Zhao, S., Liu, Z., Guo, Y., Ma, K., et al. (2022) · Translational Lung Cancer Research · doi:10.21037/tlcr-22-803 · Cited by 5
Matsuura, Y., Mun, M., Shintani, Y., Okami, J., Ito, H., Ohtsuka, T., Mori, T., WATANABE, S.-I. I., Chida, M., Endo, S., et al. (2023) · Journal of Surgical Oncology · doi:10.1002/jso.27384 · Cited by 5
Concomitant EGFR Mutations and ALK Rearrangements in Lung Adenocarcinoma Treated With Osimertinib
Thomas, D. B., Maloney, M. E., & Raval, G. G. (2023) · Cureus · doi:10.7759/cureus.48122 · Cited by 5
Gridelli, C., Tiseo, M., Cortinovis, D. L., Migliorino, M. R., Barbieri, V., Bironzo, P., Bearz, A., Attili, I., & de Marinis, F. (2023) · Current Oncology · doi:10.3390/curroncol30110729 · Cited by 5
Self-citationNicolini, A., Ferrari, P., Silvestri, R., & Bini, D. A. (2025) · MedComm · doi:10.1002/mco2.70373 · Cited by 5
Ascending role of next-generation ALK inhibitors
Costa, D. B. (2017) · The Lancet Oncology · doi:10.1016/s1470-2045(17)30338-8 · Cited by 5
Liao, B.-C., Lin, C., & Yang, J. C. (2018) · Expert Opinion on Pharmacotherapy · doi:10.1080/14656566.2018.1472765 · Cited by 5
Balzer, B. W. R., Loo, C. K. C., Wegner, E. A., Nath, C. E., Lee, S., Smith, C., Lewis, C. R., Trahair, T. N., & Anazodo, A. C. (2018) · Pediatric Hematology and Oncology · doi:10.1080/08880018.2018.1541492 · Cited by 5
Otoukesh, S., Sanchez, T., Mirshahidi, S., Wallace, D., & Mirshahidi, H. (2019) · Cancer Treatment and Research Communications · doi:10.1016/j.ctarc.2019.100149 · Cited by 5
Lorlatinib: an additional option for ALK-positive non-small cell lung cancer?
Mogenet, A., Tomasini, P., Greillier, L., & Barlési, F. (2019) · Translational Lung Cancer Research · doi:10.21037/tlcr.2019.05.10 · Cited by 5
Gobbini, É., Chiari, R., Pizzutilo, P., Bordi, P., Ghilardi, L., Pilotto, S., Osman, G. A., Cappuzzo, F., Cecere, F. L., Riccardi, F., et al. (2019) · Clinical & Translational Oncology · doi:10.1007/s12094-019-02222-8 · Cited by 5
Self-citationHuang, S., Huang, A. C., Wang, C., Chang, W., Liu, C., Pavlidis, S. P., Ko, H., Chung, F., Hsu, P., Guo, Y., et al. (2019) · Thoracic Cancer · doi:10.1111/1759-7714.13221 · Cited by 5
[Current Status for Anaplastic Lymphoma Kinase in Non-small Cell Lung Cancer].
Song, P., Zhang, L., & Shang, C. (2018) · Europe PMC (PubMed Central) · doi:10.3779/j.issn.1009-3419.2018.09.10 · Cited by 5
Raju, G. K. P., Khozin, S., Gurumurthi, K., Domike, R., & Woodcock, J. (2020) · JCO Clinical Cancer Informatics · doi:10.1200/cci.19.00103 · Cited by 5
Brigatinib in the first-line treatment of ALK+ metastatic NSCLC: safety and efficacy
Bronte, G., Cafaro, A., Pasini, L., Priano, I., Andrikou, K., Cravero, P., Burgio, M. A., Delmonte, A., & Crinò, L. (2021) · Expert Review of Anticancer Therapy · doi:10.1080/14737140.2021.1923485 · Cited by 5
Zhang, H., Shan, G., Cai, B., Bi, G., Chen, Z., Liang, J., Besskaya, V., Zheng, Y., Guo, W., Wang, L., et al. (2021) · Thoracic Cancer · doi:10.1111/1759-7714.14170 · Cited by 5
Global Research Trends in Tyrosine Kinase Inhibitors: Coword and Visualization Study
Hu, J., Xing, K., Zhang, Y., Liu, M., & Wang, Z. (2022) · JMIR Medical Informatics · doi:10.2196/34548 · Cited by 5
Singh, A. K., Kapoor, A., Noronha, V., Patil, V., Menon, N. S., Mahajan, A., Janu, A., Parandare, N., Kaushal, R., & Prabhash, K. (2022) · ecancermedicalscience · doi:10.3332/ecancer.2022.1407 · Cited by 5
Zhao, J., Li, X., Fan, R., Qin, Y., Wang, Z., Wang, B., Li, S., Fan, J., Wu, X., Liu, H., et al. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.1060460 · Cited by 5
Uhlmann, E. J., Mackel, C. E., Deforzh, E., Rabinovsky, R., Brastianos, P. K., Varma, H., Vega, R. A., & Krichevsky, A. M. (2023) · Journal of Neuro-Oncology · doi:10.1007/s11060-023-04264-z · Cited by 5
An updated patent review of anaplastic lymphoma kinase inhibitors (2018–2022)
Ma, D., Guo, M., & Zhai, X. (2023) · Expert Opinion on Therapeutic Patents · doi:10.1080/13543776.2023.2216381 · Cited by 5
Anaplastic lymphoma kinase tyrosine kinase inhibitors in non-small cell lung cancer
Vavalà, T., Mariniello, A., & Novello, S. (2018) · Translational Cancer Research · doi:10.21037/tcr.2018.10.23 · Cited by 5
Polymeric Micelles in Management of Lung Cancer
Bahman, F., Elkaissi, S., Greish, K. F., & Taurin, S. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-815720-6.00008-3 · Cited by 5
Nguyen, R., & Dyer, M. A. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-812005-7.00003-5 · Cited by 5
Kosaka, T., Yajima, T., Yamaki, E., Nakazawa, S., Tomizawa, K., Onozato, R., Yamazaki, A., Hirato, J., Yatabe, Y., Shimizu, K., et al. (2019) · Molecular and Clinical Oncology · doi:10.3892/mco.2019.1892 · Cited by 5
Liang, H., Ma, D., Xu, Y., Zhao, J., Chen, M., Liu, X., Zhong, W., Li, J., & Wang, M. (2019) · Cancer Management and Research · doi:10.2147/cmar.s213572 · Cited by 5
Urbán, L., Dóczi, R., Vodicska, B., Kormos, D., Tóth, L., Takács, I., Várkondi, E., Tihanyi, D., Lakatos, D., Dirner, A., et al. (2020) · Journal of Personalized Medicine · doi:10.3390/jpm10030107 · Cited by 5
Zou, Z., Hao, X., Zhang, C., Li, H., Dong, G., Peng, Y., Ma, K., Guo, Y., Li, S., Zhang, Y., et al. (2021) · Thoracic Cancer · doi:10.1111/1759-7714.14232 · Cited by 5
Christofyllakis, K., Monteiro, A. R., Cetin, O., Kos, I. A., Greystoke, A., & Luciani, A. (2022) · Journal of Geriatric Oncology · doi:10.1016/j.jgo.2022.04.013 · Cited by 5
Alectinib can replace crizotinib as standard first-line therapy for ALK-positive lung cancer
Uemura, T., & Hida, T. (2017) · Annals of Translational Medicine · doi:10.21037/atm.2017.08.36 · Cited by 5
Iannantuono, G. M., Giovagnoli, T., Mastrantoni, L., Gyawali, B., Floudas, C. S., Sganga, S., Giannarelli, D., Filetti, M., Spinazzola, A., Bianco, F. L., et al. (2026) · ESMO Open · doi:10.1016/j.esmoop.2026.106065 · Cited by 4
Anaplastic lymphoma kinase inhibitor development: enhanced delivery to the central nervous system
Hida, T. (2023) · Translational Lung Cancer Research · doi:10.21037/tlcr-23-43 · Cited by 4
Recent nanotechnological aspects and molecular targeting strategies for lung cancer therapy
Mishra, L., Kumari, L., Sharma, Y., Chahar, K., Kumar, M., Patel, P., Gupta, G. D., & Kurmi, B. D. (2024) · Journal of Nanoparticle Research · doi:10.1007/s11051-024-06008-0 · Cited by 4
Reale, M. L., Scattolin, D., Vitale, A., Passiglia, F., Grisanti, S., Macerelli, M., Galetta, D., Sini, C., Minuti, G., Citarella, F., et al. (2025) · Lung Cancer · doi:10.1016/j.lungcan.2025.108762 · Cited by 5
Self-citationData independent acquisition mass spectrometry (DIA-MS) in cancer studies: a concise review
Kumar, B. S. (2025) · Analytical Methods · doi:10.1039/d5ay01294e · Cited by 4
Yu, J., Zhu, M., Zhu, Y., & Shu, Q. (2026) · International Journal of Surgery · doi:10.1097/js9.0000000000004704 · Cited by 4
König, D., & Rothschild, S. I. (2020) · healthbook TIMES Oncology Hematology · doi:10.36000/hbt.oh.2020.05.019 · Cited by 4
Cho, B. C., Kim, D., Batra, U., Park, K., Kim, S., Yang, C., Voon, P. J., Sriuranpong, V., Babu, K. G., Amin, K., et al. (2022) · Cancer Research and Treatment · doi:10.4143/crt.2021.1571 · Cited by 4
Self-citationKim, M., Shim, H. S., Kim, S., Lee, I. H., Kim, J., Yoon, S., Kim, H., Park, I., Jeong, J. H., Yoo, C., et al. (2024) · Journal of Pathology and Translational Medicine · doi:10.4132/jptm.2023.11.01 · Cited by 5
Poei, D., Ali, S., Thomas, J. S., Nieva, J. J., & Hsu, R. C. (2025) · Cancer Research Communications · doi:10.1158/2767-9764.crc-24-0504 · Cited by 4
Onesti, C. E., Iacono, D., Angelini, S., Mazzotta, M., Giusti, R., Lauro, S. D., & Marchetti, P. (2018) · Anti-Cancer Drugs · doi:10.1097/cad.0000000000000699 · Cited by 4
Leone, G., Passiglia, F., Bironzo, P., Bertaglia, V., & Novello, S. (2020) · Translational Lung Cancer Research · doi:10.21037/tlcr-20-710 · Cited by 4
O’Leary, C. G., McSorley, L. M., Hennessy, B. T., Grogan, L., Breathnach, O. S., & Morris, P. G. (2020) · Expert Opinion on Pharmacotherapy · doi:10.1080/14656566.2020.1801639 · Cited by 4
Andreev, D. A., Zav’yalov, A. A., Polyakova, K. I., & Davydovskaуa, M. V. (2020) · PULMONOLOGIYA · doi:10.18093/0869-0189-2020-30-4-463-472 · Cited by 4
Marín, E., Reyes, R., Arcocha, A., Viñolas, N., Mezquita, L., Gonzalvo, E., de Gordoa, K. S., Jares, P., Reguart, N., & Teixidó, C. (2020) · Diagnostics · doi:10.3390/diagnostics10110902 · Cited by 4
Personalized Medicine in Oncology
Vanderwalde, A. M. (2022) · MDPI eBooks · doi:10.3390/books978-3-0365-2820-5 · Cited by 4
Tan, A. C., Tan, S. H., Zhou, S., Peters, S., Curigliano, G., & Tan, D. S. W. (2022) · Cancer Treatment Reviews · doi:10.1016/j.ctrv.2022.102354 · Cited by 4
Self-citationRole ofSTK11inALK‑positive non‑small cell lung cancer (Review)
Zhou, W., Yan, L.-D., Yu, Z.-Q., Li, N., Yang, Y., Wang, M., Chen, Y., Mao, M.-X., Peng, X., & Cai, J. (2022) · Oncology Letters · doi:10.3892/ol.2022.13301 · Cited by 4
Su, C., Zhou, J., Qiang, H., Zhao, J., Chang, Q., Ji, X., Li, J., Xie, M., & Chu, T. (2022) · International Journal of Cancer · doi:10.1002/ijc.34123 · Cited by 4
Liao, J., Guan, H., Yu, M., Zhou, P., Han, Y., Peng, X., & Zhang, S. (2022) · Investigational New Drugs · doi:10.1007/s10637-022-01270-2 · Cited by 4
Gupta, D., Gupta, N. M., Singh, N., & Prinja, S. (2024) · JCO Global Oncology · doi:10.1200/go.23.00260 · Cited by 4
Carlo, E. D., Savio, M. C. D., Polesel, J., Ros, V. D., Berto, E., Santarossa, S., Chimienti, E., Fratino, L., & Bearz, A. (2018) · Oncotarget · doi:10.18632/oncotarget.24573 · Cited by 4
Pinsolle, J., Terzi, N., Ferrer, L., Levra, M. G., Toffart, A., & Moro‐Sibilot, D. (2019) · Médecine Intensive Réanimation · doi:10.3166/rea-2019-0091 · Cited by 4
Self-citationRapoport, B. L., Arani, R. B., Mathieson, N., & Krendyukov, A. (2019) · Future Oncology · doi:10.2217/fon-2018-0863 · Cited by 4
Targeted Therapy for Non-Small Cell Lung Cancer
Kim, J. S., & Kang, E. J. (2020) · Korean Journal of Medicine · doi:10.3904/kjm.2020.95.2.78 · Cited by 4
Tsakonas, G., Kamali, C., Petris, L. D., Friesland, S., Lewensohn, R., & Ekman, S. (2020) · Cancers · doi:10.3390/cancers12071804 · Cited by 4
Liu, L., Hou, F., Liu, Y., Li, W., & Zhang, H. (2022) · Journal of the National Comprehensive Cancer Network · doi:10.6004/jnccn.2021.7077 · Cited by 4
Alectinib treatment response in lung adenocarcinoma patient with novel EML4‐ALK variant
Song, P., Zhang, J., Shang, C., & Zhang, L. (2018) · Thoracic Cancer · doi:10.1111/1759-7714.12834 · Cited by 4
Stratégies thérapeutiques dans le cancer bronchique non à petites cellules ALK positif de stade IV
Tiotiu, A. I., Billon, Y., Vaillant, P., Ménard, O., Hofman, P. M., & Mascaux, C. (2019) · Revue des Maladies Respiratoires · doi:10.1016/j.rmr.2019.02.008 · Cited by 4
Taketa, T., & Nakamura, T. (2021) · Clinical Case Reports · doi:10.1002/ccr3.3927 · Cited by 4
Lasala, R., Santoleri, F., Romagnoli, A., Musicco, F., & Costantini, A. (2019) · European Journal of Clinical Pharmacology · doi:10.1007/s00228-018-02621-w · Cited by 4
An Ascendant Challenge: Central Nervous System Metastases in ALK + Lung Cancers
Murciano-Goroff, Y. R., Harada, G., & Drilon, A. (2022) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-22-0341 · Cited by 4
Podder, V., Bellur, S. S., Margolin, K. A., Advani, P. P., Mahtani, R. L., Subbiah, V., Novo, G. B., Ranjan, T., & Ahluwalia, M. S. (2024) · Current Oncology Reports · doi:10.1007/s11912-024-01593-8 · Cited by 4
SDMap: a comprehensive database of spatial drug perturbation maps
Li, F., Chen, Z., Zhang, Y., Ye, X., Fan, W., 康安辉, Song, X., Pei, L., Quan, Q., Liu, W., et al. (2025) · Nucleic Acids Research · doi:10.1093/nar/gkaf1046 · Cited by 3
Sharkawy, S., Acharya, S., Kostrhunová, H., Maji, M., Marková, L., Novohradský, V., Gibson, D., & Brabec, V. (2025) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.5c01858 · Cited by 3
Metadata
- Authors
- Soria, J.-C., Tan, D. S. W., Chiari, R., Wu, Y.-L., Paz-Ares, L., Wolf, J., Geater, S. L., Orlov, S., Cortinovis, D., Yu, C.-J., Hochmair, M., Cortot, A. B., Tsai, C.-M., Moro-Sibilot, D., Campelo, R. G., McCulloch, T., Sen, P., Dugan, M., Pantano, S., Branle, F., Massacesi, C., & de Castro, G.
- Affiliations
- Université Paris-Sud (FR)
- National Cancer Centre Singapore (SG)
- Azienda Ospedaliera di Perugia (IT)
- Guangdong General Hospital (CN)
- Universidad Complutense de Madrid (ES)
- University Hospital Cologne (DE)
- Songklanagarind Hospital (TH)
- Azienda Ospedaliera San Gerardo (IT)
- National Taiwan University Hospital (TW)
- Otto Wagner Hospital (AT)
- Centre Hospitalier Universitaire de Lille (FR)
- Taipei Veterans General Hospital (TW)
- Universidade da Coruña (ES)
- Novartis (Switzerland) (CH)
- Corresponding author
- Soria, Jean-Charles
- ORCID
- Venue
- The Lancet
- Publisher
- Elsevier BV
- Published
- 2017-03
- Volume
- 389
- Issue
- 10072
- Pages
- 917-929
- ISSN
- 0099-5355 (ISSN-L)
- 0140-6736
- OpenAlex
- W2581996620
- Cited by
- 1,151
- References
- 26
- Citations by year
- 2026: 38 · 2025: 73 · 2024: 98 · 2023: 123 · 2022: 142 · 2021: 128 · 2020: 139 · 2019: 146 · 2018: 168 · 2017: 94
- FWCI
- 123.94
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The Lancet (publishedVersion)
- PubMed (publishedVersion)
- Kölner Universitäts PublikationsServer (Universität zu Köln) (publishedVersion)
- BOA (University of Milano-Bicocca) (submittedVersion)
- Topics
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Lung Cancer Treatments and Mutations
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Lung Cancer Diagnosis and Treatment
- Health Sciences › Medicine › Oncology › Lung Cancer Research Studies
- Keywords
- ceritinib, anaplastic lymphoma kinase, ALK-positive non-small cell lung cancer, first-line therapy, platinum-based chemotherapy, pemetrexed, progression-free survival, targeted therapy, adverse events, diarrhea, elevated liver enzymes, brain metastases, treatment safety and efficacy comparison, WHO performance status
- MeSH terms
- Pemetrexed, Adult, Aged, Aged, 80 and over, Antineoplastic Agents, Antineoplastic Combined Chemotherapy Protocols, Carcinoma, Non-Small-Cell Lung, Cisplatin, Female, Humans, Lung Neoplasms, Male, Middle Aged, Pyrimidines, Sulfones, Carboplatin, Treatment Outcome, Disease-Free Survival, Kaplan-Meier Estimate, Young Adult
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review