The DOI matches its Crossref record; 56 of the 56 references it cites were found in a registry or an index.
Idiopathic nephrotic syndrome in children
Abstract
The incidence of idiopathic nephrotic syndrome (NS) is 1·15-16·9 per 100 000 children, varying by ethnicity and region. The cause remains unknown but the pathogenesis of idiopathic NS is thought to involve immune dysregulation, systemic circulating factors, or inherited structural abnormalities of the podocyte. Genetic risk is more commonly described among children with steroid-resistant disease. The mainstay of therapy is prednisone for the vast majority of patients who are steroid responsive; however, the disease can run a frequently relapsing course, necessitating the need for alternative immunosuppressive agents. Infection and venous thromboembolism are the main complications of NS with also increased risk of acute kidney injury. Prognosis in terms of long-term kidney outcome overall is excellent for steroid-responsive disease, and steroid resistance is an important determinant of future risk of chronic or end-stage kidney disease.
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ADOLESCENTS, E. P. O. I. G. F. C. H. A. R. R. I. C. A. (2011) · Pediatrics · doi:10.1542/peds.2009-2107c · Cited by 2,585
PATHOGENESIS OF LIPOID NEPHROSIS: A DISORDER OF T-CELL FUNCTION
Shalhoub, R. (1974) · The Lancet · doi:10.1016/s0140-6736(74)91880-7 · Cited by 1,192
(2012) · Kidney International Supplements · doi:10.1038/kisup.2012.9 · Cited by 966
Circulating urokinase receptor as a cause of focal segmental glomerulosclerosis
Wei, C., El Hindi, S., Li, J., Fornoni, A., Goes, N., Sageshima, J., Maiguel, D., Karumanchi, S. A., Yap, H.-K., Saleem, M., et al. (2011) · Nature Medicine · doi:10.1038/nm.2411 · Cited by 841
Focal Segmental Glomerulosclerosis
D'Agati, V. D., Kaskel, F. J., & Falk, R. J. (2011) · New England Journal of Medicine · doi:10.1056/nejmra1106556 · Cited by 825
(2012) · PsycEXTRA Dataset · doi:10.1037/e531652012-001 · Cited by 697
A single-gene cause in 29.5% of cases of steroid-resistant nephrotic syndrome
Sadowski, C. E., Lovric, S., Ashraf, S., Pabst, W. L., Gee, H. Y., Kohl, S., Engelmann, S., Vega-Warner, V., Fang, H., Halbritter, J., et al. (2015) · Journal of the American Society of Nephrology · doi:10.1681/asn.2014050489 · Cited by 651
Induction of B7-1 in podocytes is associated with nephrotic syndrome
Reiser, J., von Gersdorff, G., Loos, M., Oh, J., Asanuma, K., Giardino, L., Rastaldi, M. P., Calvaresi, N., Watanabe, H., Schwarz, K., et al. (2004) · Journal of Clinical Investigation · doi:10.1172/jci200420402 · Cited by 589
Vivarelli, M., Massella, L., Ruggiero, B., & Emma, F. (2017) · Clinical Journal of the American Society of Nephrology · doi:10.2215/cjn.05000516 · Cited by 557
Iijima, K., Sako, M., Nozu, K., Mori, R., Tuchida, N., Kamei, K., Miura, K., Aya, K., Nakanishi, K., Ohtomo, Y., et al. (2014) · The Lancet · doi:10.1016/s0140-6736(14)60541-9 · Cited by 451
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Cited by
on behalf of the International Pediatric Nephrology Association, Trautmann, A., Vivarelli, M., Samuel, S., Gipson, D., Sinha, A., Schaefer, F., Hui, N. K., Boyer, O., Saleem, M. A., et al. (2020) · Pediatric Nephrology · doi:10.1007/s00467-020-04519-1 · Cited by 389
Trautmann, A., Boyer, O., Hodson, E., Bagga, A., Gipson, D. S., Samuel, S., Wetzels, J., Alhasan, K., Banerjee, S., Bhimma, R., et al. (2023) · Pediatric Nephrology · doi:10.1007/s00467-022-05739-3 · Cited by 292
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Metadata
- Authors
- Noone, D. G., Iijima, K., & Parekh, R.
- Venue
- The Lancet
- Publisher
- Elsevier BV
- Published
- 2018-07
- Volume
- 392
- Issue
- 10141
- Pages
- 61-74
- ISSN
- 0099-5355 (ISSN-L)
- 0140-6736
- OpenAlex
- W2808503484
- Cited by
- 586
- References
- 56
- FWCI
- 34.19
- Type
- journal article
- Language
- en
- Open access
- closed
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