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Cited by 450

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Burden of disease in Brazil, 1990–2016: a systematic subnational analysis for the Global Burden of Disease Study 2016

Open access
Marinho, Fatima, de Azeredo Passos, Valéria Maria, Carvalho Malta, Deborah, Barboza França, Elizabeth, Abreu, Daisy M X, Araújo, Valdelaine E M, Bustamante-Teixeira, Maria Teresa, Camargos, Paulo A M, da Cunha, Carolina Cândida, Duncan, Bruce Bartholow, Felisbino-Mendes, Mariana Santos, Guerra, Maximiliano Ribeiro, Guimaraes, Mark D C, Lotufo, Paulo A, Marcenes, Wagner, Oliveira, Patricia Pereira Vasconcelos, de Moares Pedroso, Marcel, Ribeiro, Antonio L, Schmidt, Maria Inês, Teixeira, Renato Azeredo, Vasconcelos, Ana Maria Nogales, Barreto, Mauricio L, Bensenor, Isabela M, Brant, Luisa C C, Claro, Rafael M, Costa Pereira, Alexandre, Cousin, Ewerton, Curado, Maria Paula, dos Santos, Kadine Priscila Bender, Faro, André, Ferri, Cleusa P, Furtado, João M, Gall, Julia, Glenn, Scott D, Goulart, Alessandra Carvalho, Ishitani, Lenice Harumi, Kieling, Christian, Ladeira, Roberto Marini, Machado, Isis Eloah, Martins, Sheila Cristina Ouriques, Martins-Melo, Francisco Rogerlândio, Melo, Ana Paula Souto, Miller-Petrie, Molly K, Mooney, Meghan D, Nunes, Bruno P, Palone, Marcos Roberto Tovani, Pereira, Claudia C, Rasella, Davide, Ray, Sarah E, Roever, Leonardo, de Freitas Saldanha, Raphael, Santos, Itamar S, Schneider, Ione J C, Santos Silva, Diego Augusto, Silveira, Dayane Gabriele Alves, Soares Filho, Adauto Martins, Moraes Sousa, Tatiane Cristina, Szwarcwald, Celia L, Traebert, Jefferson, Velasquez-Melendez, Gustavo, Wang, Yuan-Pang, Lozano, Rafael, Murray, Christopher J L, Naghavi, Mohsen·2018·The Lancet

Abstract

BACKGROUND: Political, economic, and epidemiological changes in Brazil have affected health and the health system. We used the Global Burden of Disease Study 2016 (GBD 2016) results to understand changing health patterns and inform policy responses. METHODS: We analysed GBD 2016 estimates for life expectancy at birth (LE), healthy life expectancy (HALE), all-cause and cause-specific mortality, years of life lost (YLLs), years lived with disability (YLDs), disability-adjusted life-years (DALYs), and risk factors for Brazil, its 26 states, and the Federal District from 1990 to 2016, and compared these with national estimates for ten comparator countries. FINDINGS: Nationally, LE increased from 68·4 years (95% uncertainty interval [UI] 68·0-68·9) in 1990 to 75·2 years (74·7-75·7) in 2016, and HALE increased from 59·8 years (57·1-62·1) to 65·5 years (62·5-68·0). All-cause age-standardised mortality rates decreased by 34·0% (33·4-34·5), while all-cause age-standardised DALY rates decreased by 30·2% (27·7-32·8); the magnitude of declines varied among states. In 2016, ischaemic heart disease was the leading cause of age-standardised YLLs, followed by interpersonal violence. Low back and neck pain, sense organ diseases, and skin diseases were the main causes of YLDs in 1990 and 2016. Leading risk factors contributing to DALYs in 2016 were alcohol and drug use, high blood pressure, and high body-mass index. INTERPRETATION: Health improved from 1990 to 2016, but improvements and disease burden varied between states. An epidemiological transition towards non-communicable diseases and related risks occurred nationally, but later in some states, while interpersonal violence grew as a health concern. Policy makers can use these results to address health disparities. FUNDING: Bill & Melinda Gates Foundation and the Brazilian Ministry of Health.

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Authors
Marinho, F., de Azeredo Passos, V. M., Carvalho Malta, D., Barboza França, E., Abreu, D. M. X., Araújo, V. E. M., Bustamante-Teixeira, M. T., Camargos, P. A. M., da Cunha, C. C., Duncan, B. B., Felisbino-Mendes, M. S., Guerra, M. R., Guimaraes, M. D. C., Lotufo, P. A., Marcenes, W., Oliveira, P. P. V., de Moares Pedroso, M., Ribeiro, A. L., Schmidt, M. I., Teixeira, R. A., Vasconcelos, A. M. N., Barreto, M. L., Bensenor, I. M., Brant, L. C. C., Claro, R. M., Costa Pereira, A., Cousin, E., Curado, M. P., dos Santos, K. P. B., Faro, A., Ferri, C. P., Furtado, J. M., Gall, J., Glenn, S. D., Goulart, A. C., Ishitani, L. H., Kieling, C., Ladeira, R. M., Machado, I. E., Martins, S. C. O., Martins-Melo, F. R., Melo, A. P. S., Miller-Petrie, M. K., Mooney, M. D., Nunes, B. P., Palone, M. R. T., Pereira, C. C., Rasella, D., Ray, S. E., Roever, L., de Freitas Saldanha, R., Santos, I. S., Schneider, I. J. C., Santos Silva, D. A., Silveira, D. G. A., Soares Filho, A. M., Moraes Sousa, T. C., Szwarcwald, C. L., Traebert, J., Velasquez-Melendez, G., Wang, Y.-P., Lozano, R., Murray, C. J. L., & Naghavi, M.
Venue
The Lancet
Publisher
Elsevier BV
Published
2018-09
Volume
392
Issue
10149
Pages
760-775
ISSN
  • 0099-5355 (ISSN-L)
  • 0140-6736
OpenAlex
W2883056653
Cited by
450
References
8
FWCI
125.65
Type
journal article
Language
en
Open access
hybrid

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CoChat. (2026). Citation check: Burden of disease in Brazil, 1990–2016: a systematic subnational analysis for the Global Burden of Disease Study 2016. https://app.cochat.ai/papers/10.1016/s0140-6736(18)31221-2
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Marinho, F., de Azeredo Passos, V. M., Carvalho Malta, D., Barboza França, E., Abreu, D. M. X., Araújo, V. E. M., Bustamante-Teixeira, M. T., Camargos, P. A. M., da Cunha, C. C., Duncan, B. B., Felisbino-Mendes, M. S., Guerra, M. R., Guimaraes, M. D. C., Lotufo, P. A., Marcenes, W., Oliveira, P. P. V., de Moares Pedroso, M., Ribeiro, A. L., Schmidt, M. I., . . . Naghavi, M. (2018). Burden of disease in Brazil, 1990–2016: a systematic subnational analysis for the Global Burden of Disease Study 2016. The Lancet. https://doi.org/10.1016/s0140-6736(18)31221-2

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.