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Lowering systolic blood pressure to less than 120 mm Hg versus less than 140 mm Hg in patients with high cardiovascular risk with and without diabetes or previous stroke: an open-label, blinded-outcome, randomised trial
Abstract
Background Uncertainty exists about whether lowering systolic blood pressure to less than 120 mm Hg is superior to that of less than 140 mm Hg, particularly in patients with diabetes and patients with previous stroke. Methods In this open-label, blinded-outcome, randomised controlled trial, participants with high cardiovascular risk were enrolled from 116 hospitals or communities in China. We used minimised randomisation to assign participants to intensive treatment targeting standard office systolic blood pressure of less than 120 mm Hg or standard treatment targeting less than 140 mm Hg. The primary outcome was a composite of myocardial infarction, revascularisation, hospitalisation for heart failure, stroke, or death from cardiovascular causes, assessed by the intention-to-treat principle. This trial was registered with ClinicalTrials.gov, NCT04030234. Findings Between Sept 17, 2019, and July 13, 2020, 11 255 participants (4359 with diabetes and 3022 with previous stroke) were assigned to intensive treatment (n=5624) or standard treatment (n=5631). Their mean age was 64·6 years (SD 7·1). The mean systolic blood pressure throughout the follow-up (except the first 3 months of titration) was 119·1 mm Hg (SD 11·1) in the intensive treatment group and 134·8 mm Hg (10·5) in the standard treatment group. During a median of 3·4 years of follow-up, the primary outcome event occurred in 547 (9·7%) participants in the intensive treatment group and 623 (11·1%) in the standard treatmen…
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“The primary outcome, a composite of MI, revascularization, hospitalization for heart failure, stroke, or cardiovascular death, was significantly reduced by 12% in the intensive therapy group (HR 0.88, 95% CI 0.78–0.99) irrespective of the diagnosis of diabetes at baseline.”
From 10. Cardiovascular Disease and Risk Management: Standards of Care in Diabetes—2026 (2026) · cites this paper as [43]
In the citing paper
“The results of BPROAD and ESPRIT highlight that targeting an on-treatment systolic blood pressure goal of <120 mmHg in people with high cardiovascular risk is associated with reduction in cardiovascular events compared with systolic blood pressure <140 mmHg.”
From 10. Cardiovascular Disease and Risk Management: Standards of Care in Diabetes—2026 (2026) · cites this paper as [43]
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“The investigators reported a modest increase in adverse events, including syncope (0.4% vs. 0.1%, HR 3.00, 95% CI 1.35–6.68) (43).”
From 10. Cardiovascular Disease and Risk Management: Standards of Care in Diabetes—2026 (2026) · cites this paper as [43]
Citations
Cites
Global Burden of Cardiovascular Diseases and Risk Factors, 1990–2019
Roth, G. A., Mensah, G. A., Johnson, C. O., Addolorato, G., Ammirati, E., Baddour, L. M., Barengo, N. C., Beaton, A. Z., Benjamin, E. J., Benziger, C. P., et al. (2020) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2020.11.010 · Cited by 11,449
Self-citationA Randomized Trial of Intensive versus Standard Blood-Pressure Control
The SPRINT Research Group (2015) · New England Journal of Medicine · doi:10.1056/nejmoa1511939 · Cited by 6,325
Hansson, L., Zanchetti, A., Carruthers, S. G., Dahlöf, B., Elmfeldt, D., Julius, S., Ménard, J., Rahn, K. H., Wedel, H., & Westerling, S. (1998) · The Lancet · doi:10.1016/s0140-6736(98)04311-6 · Cited by 5,728
Sever, P., Dahlöf, B., Poulter, N. R., Wedel, H., Beevers, G., Caulfield, M. J., Collins, R., Kjeldsen, S. E., Kristinsson, A., McInnes, G. T., et al. (2003) · The Lancet · doi:10.1016/s0140-6736(03)12948-0 · Cited by 3,790
Ettehad, D., Emdin, C. A., Kiran, A., Anderson, S. G., Callender, T., Emberson, J., Chalmers, J., Rodgers, A., & Rahimi, K. (2016) · The Lancet · doi:10.1016/s0140-6736(15)01225-8 · Cited by 3,755
Effects of intensive blood-pressure control in type 2 diabetes mellitus
(2010) · New England Journal of Medicine · doi:10.1056/nejmoa1001286 · Cited by 3,598
Mancia, G., Kreutz, R., Brunström, M., Burnier, M., Grassi, G., Januszewicz, A., Muiesan, M. L., Tsioufis, K., Agabiti-Rosei, E., Algharably, E. A. E., et al. (2023) · Journal of Hypertension · doi:10.1097/hjh.0000000000003480 · Cited by 3,473
Self-citationDahlöf, B., Sever, P. S., Poulter, N. R., Wedel, H., Beevers, D. G., Caulfield, M., Collins, R., Kjeldsen, S. E., Kristinsson, A., McInnes, G. T., et al. (2005) · The Lancet · doi:10.1016/s0140-6736(05)67185-1 · Cited by 2,909
Rahimi, K., Bidel, Z., Nazarzadeh, M., Copland, E., Canoy, D., Ramakrishnan, R., Pinho-Gomes, A.-C., Woodward, M., Adler, A., Agodoa, L., et al. (2021) · The Lancet · doi:10.1016/s0140-6736(21)00590-0 · Cited by 1,074
Self-citationXie, X., Atkins, E., Lv, J., Bennett, A., Neal, B., Ninomiya, T., Woodward, M., MacMahon, S., Turnbull, F., Hillis, G. S., et al. (2016) · The Lancet · doi:10.1016/s0140-6736(15)00805-3 · Cited by 980
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- Whelton, 2018, Circulation, 138, e426
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Tian, X., Wu, S., Xia, X., Xu, Q., Chen, S., Wang, A., & Fang, R. (2026) · Diabetes Obesity and Metabolism · doi:10.1111/dom.70472
Self-citationXia, X., Chen, S., Tian, X., Xu, Q., Li, H., Zhang, Y., Zhang, X., Li, J., Wu, S., & Wang, A. T. (2026) · Mayo Clinic Proceedings · doi:10.1016/j.mayocp.2025.10.022
Self-citationZhang, Y., Zhang, Y., Yang, S., Gan, X., Huang, Y., Zhang, Y., Wu, Y., Hou, F. F., & Qin, X. (2026) · BMJ Medicine · doi:10.1136/bmjmed-2025-001791
Self-citationTian, Z., Sternberg, M., Willerding, J. M., Schmidt-Ott, K. M., Melk, A., & Schmidt, B. (2026) · medRxiv · doi:10.64898/2026.01.28.26345070
Martins, E. D., Tavares, C. A. M., Favaro, L., Monfardini, F., Mourad, J., Khunti, K., Savarese, G., Berwanger, O., & Santo, K. (2026) · American Heart Journal · doi:10.1016/j.ahj.2026.107380
Hypertension in Women Across the Life Cycle: Unique Aspects and Challenges
Bond, R. M., Purewal, V. S., Cameron, N. A., Tobb, K., Adedinsewo, D. A., Isiadinso, I., & Phillips, K. A. (2026) · Current Hypertension Reports · doi:10.1007/s11906-026-01362-x · Cited by 6
Real-World Adoption of the 2021 KDIGO BP Guideline in CKD
Lee, H., Cho, S. M. J., McCarthy, C. P., Yoo, T., Wadhera, R. K., Secemsky, E. A., & Natarajan, P. (2026) · Journal of the American Society of Nephrology · doi:10.1681/asn.0000001046 · Cited by 2
Eschenhagen, T., & Weil, J. (2026) · Springer eBooks · doi:10.1007/978-3-662-72738-6_6
Reduction of Antihypertensive Treatment in Nursing Home Residents
Bénétos, A., Gautier, S., & Rossignol, P. (2026) · New England Journal of Medicine · doi:10.1056/nejmc2518217
Liu, S., Yin, Y., Yang, H., Sun, L., (5906), J. W., Zhou, Y., Guan, L., Xing, L., Xie, Z., Ye, N., et al. (2026) · BMC Medicine · doi:10.1186/s12916-026-04678-2
Self-citation
Metadata
- Authors
- Liu, J., Li, Y., Ge, J., Yan, X., Zhang, H., Zheng, X., Lu, J., Li, X., Gao, Y., Lei, L., Liu, J., Li, J., Ai, X., An, C., An, Y., Bai, S., Bai, X., Bi, J., Bin, X., Bu, M., Bu, P., Bu, W., Cai, L., Cai, N., Cai, S., Cai, T., Cai, W., Cao, B., Cao, B., Cao, H., Cao, L., Cao, X., Chai, H., Chai, Y., Chai, Z., Chang, C., Chang, J., Chang, S., Chang, Y., Chao, H., Che, H., Che, Q., Chen, D., Chen, D., Chen, F., Chen, G., Chen, H., Chen, H., Chen, H., Chen, H., Chen, J., Chen, J., Chen, J., Chen, J., Chen, J., Chen, J., Chen, J., Chen, L., Chen, L., Chen, L., Chen, Q., Chen, R., Chen, S., Chen, S., Chen, T., Chen, X., Chen, X., Chen, X., Chen, X., Chen, X., Chen, Y., Chen, Y., Chen, Y., Chen, Y., Chen, Y., Chen, Z., Chen, Z., Chen, Z., Cheng, C., Cheng, J., Cheng, X., Chu, J., Cui, R., Cui, X., Cui, X., Cui, Y., Cui, Z., Dai, W., Dai, X., Ding, C., Ding, H., Ding, Q., Ding, Y., Ding, Y., Dong, J., Dong, L., Dong, Q., Dong, Y., Du, B., Du, H., Du, J., Du, L., Du, M., Du, Q., Du, T., Du, X., Duan, R., Duan, X., Duan, X., Fan, D., Fan, X., Fan, X., Fang, F., Fang, J., Fang, X., Fang, Y., Feng, E., Feng, H., Feng, L., Feng, R., Feng, Z., Fu, H., Fu, Q., Gao, H., Gao, L., Gao, L., Gao, L., Gao, L., Gao, M., Gao, M., Gao, Q., Gao, Y., Gao, Y., Ge, J., Geng, H., Geng, H., Geng, L., Geng, L., Gou, H., Gu, Q., Guan, L., Guan, S., Guan, W., Guan, Z., Guang, B., Guo, A., Guo, C., Guo, G., Guo, L., Guo, Q., Guo, Q., Guo, Y., Guo, Z., Han, A., Han, M., Han, S., Han, X., Han, Y., Hao, F., Hao, J., Hao, S., He, C., He, D., He, M., He, M., He, S., He, W., He, X., He, Y., Hong, J., Hou, C., Hou, J., Hu, D., Hu, J., Hu, J., Hu, L., Hu, M., Hu, Z., Huang, A., Huang, C., Huang, H., Huang, J., Huang, S., Huang, S., Huang, W., Huang, W., Huang, X., Huang, X., Huang, X., Hui, J., Hui, L., Hui, Z., Huo, F., Ji, R., Ji, R., Jia, G., Jia, H., Jia, J., Jia, J., Jia, X., Jiang, H., Jiang, J., Jiang, Q., Jiang, X., Jiang, X., Jiang, Y., Jiao, Y., Jie, L., Jin, B., Jin, L., Jin, R., Jin, R., Jin, X., Jin, X., Jin, Y., Jin, Z., Jin, Z., Jing, C., Jing, J., Jing, R., Kang, L., Kang, Y., Kong, J., Kou, S., Kou, X., Kulaxihan, Lai, J., Lei, L., Li, B., Li, B., Li, B., Li, C., Li, C., Li, C., Li, C., Li, D., Li, D., Li, D., Li, F., Li, G., Li, H., Li, H., Li, J., Li, J., Li, J., Li, J., Li, J., Li, J., Li, J., Li, J., Li, L., Li, L., Li, L., Li, L., Li, L., Li, M., Li, M., Li, M., Li, N., Li, N., Li, N., Li, N., Li, Q., Li, Q., Li, R., Li, R., Li, S., Li, S., Li, S., Li, S., Li, T., Li, T., Li, W., Li, W., Li, W., Li, W., Li, X., Li, X., Li, X., Li, X., Li, X., Li, X., Li, Y., Li, Y., Li, Y., Li, Y., Li, Y., Li, Y., Li, Y., Li, Y., Li, Z., Li, Z., Liang, C., Liang, J., Liang, J., Liang, K., Liang, L., Liang, T., Liang, X., Liang, X., Liang, Y., Liang, Z., Lie, Z., Lin, Q., Lin, R., Lin, X., Lin, Z., Liu, A., Liu, C., Liu, C., Liu, C., Liu, F., Liu, F., Liu, G., Liu, H., Liu, J., Liu, J., Liu, J., Liu, J., Liu, J., Liu, J., Liu, J., Liu, J., Liu, J., Liu, L., Liu, L., Liu, L., Liu, L., Liu, L., Liu, L., Liu, Q., Liu, Q., Liu, Q., Liu, Q., Liu, S., Liu, X., Liu, X., Liu, X., Liu, X., Liu, X., Liu, Y., Liu, Y., Liu, Y., Liu, Y., Liu, Y., Liu, Z., Long, J., Lu, F., Lu, H., Lu, J., Lu, J., Lu, W., Lu, Y., Lu, Y., Luan, T., Luo, Q., Luo, Q., Luo, T., Luo, X., Luo, Y., Lv, J., Lv, J., Lv, L., Lv, L., Lv, M., Ma, A., Ma, H., Ma, H., Ma, J., Ma, J., Ma, L., Ma, L., Ma, N., Ma, Q., Ma, S., Ma, T., Ma, X., Ma, X., Ma, Y., Mai, L., Mei, X., Meng, G., Miao, R., Miao, X., Miao, X., Min, T., Mo, S., Morigentu, Nan, T., Ni, J., Ni, S., Nie, Y., Ning, B., Ning, X., Niu, M., Niu, Q., Niu, W., Niu, X., Ou, F., Pan, B., Pan, C., Pan, C., Pan, J., Pan, X., Pan, Z., Pei, G., Pei, L., Pei, M., Pei, Y., Peng, Y., Peng, Y., Pu, Z., Qi, F., Qi, L., Qi, M., Qi, Y., Qian, J., Qin, L., Qin, Z., Qing, L., Qiu, L., Qiu, W., Qiu, X., Qu, Y., Quan, M., Ren, D., Ren, H., Ren, L., Ren, T., Ren, W., Ren, Y., Rong, Y., Ruan, J., Shang, P., Shao, M., Shao, X., Shao, Y., Shen, J., Shen, R., Sheng, L., Shi, J., Shi, X., Shi, Y., Shi, Y., Shi, Y., Shu, B., Song, B., Song, D., Song, J., Song, J., Song, J., Song, W., Song, X., Song, Y., Su, H., Su, Q., Su, S., Su, X., Sun, C., Sun, F., Sun, G., Sun, J., Sun, M., Sun, R., Sun, S., Sun, S., Sun, Y., Sun, Y., Sun, Y., Sun, Z., Suo, M., Tan, B., Tang, C., Tang, Z., Tao, Y., Tian, C., Tian, H., Tian, J., Tian, X., Wan, H., Wan, Q., Wan, R., Wang, B., Wang, C., Wang, C., Wang, C., Wang, D., Wang, E., Wang, F., Wang, G., Wang, G., Wang, G., Wang, H., Wang, H., Wang, H., Wang, J., Wang, J., Wang, J., Wang, J., Wang, J., Wang, K., Wang, L., Wang, L., Wang, L., Wang, L., Wang, M., Wang, P., Wang, Q., Wang, Q., Wang, Q., Wang, Q., Wang, R., Wang, S., Wang, S., Wang, T., Wang, T., Wang, T., Wang, T., Wang, W., Wang, W., Wang, W., Wang, W., Wang, W., Wang, X., Wang, X., Wang, X., Wang, X., Wang, Y., Wang, Y., Wang, Y., Wang, Y., Wang, Y., Wang, Y., Wang, Y., Wang, Y., Wang, Y., Wang, Y., Wang, Y., Wang, Y., Wang, Y., Wang, Y., Wang, Z., Wang, Z., Wang, Z., Wei, C., Wei, L., Wei, P., Wei, S., Wei, X., Wen, H., Wen, Y., Wu, C., Wu, H., Wu, L., Wu, L., Wu, Q., Wu, S., Wu, W., Wu, X., Wu, Y., Wu, Z., Wu, Z., Wu, Z., Wuhanbilige, Xia, J., Xia, Y., Xiang, J., Xiao, H., Xiao, Y., Xie, M., Xie, Y., Xin, H., Xing, J., Xiu, G., Xu, B., Xu, C., Xu, E., Xu, J., Xu, S., Xu, W., Xu, W., Xue, N., Xue, T., Xue, W., Yan, H., Yan, X., Yan, Y., Yang, B., Yang, H., Yang, H., Yang, J., Yang, K., Yang, M., Yang, M., Yang, N., Yang, P., Yang, X., Yang, X., Yang, X., Yang, X., Yang, X., Yang, X., Yang, Y., Yang, Y., Yang, Y., Yang, Y., Yang, Z., Yang, Z., Yao, H., Yao, L., Ye, J., Ye, W., Yi, M., Yi, S., Yi, W., Yi, Z., Yin, G., Yin, G., Yu, G., Yu, H., Yu, H., Yu, L., Yu, L., Yu, N., Yu, Q., Yu, X., Yu, Y., Yuan, B., Zeng, C., Zhai, N., Zhai, X., Zhan, H., Zhang, A., Zhang, B., Zhang, B., Zhang, C., Zhang, C., Zhang, C., Zhang, C., Zhang, C., Zhang, F., Zhang, F., Zhang, G., Zhang, H., Zhang, H., Zhang, H., Zhang, H., Zhang, H., Zhang, H., Zhang, J., Zhang, J., Zhang, J., Zhang, J., Zhang, J., Zhang, L., Zhang, L., Zhang, L., Zhang, L., Zhang, L., Zhang, L., Zhang, L., Zhang, L., Zhang, M., Zhang, P., Zhang, Q., Zhang, R., Zhang, R., Zhang, S., Zhang, S., Zhang, S., Zhang, T., Zhang, W., Zhang, W., Zhang, X., Zhang, X., Zhang, X., Zhang, X., Zhang, X., Zhang, X., Zhang, X., Zhang, Y., Zhang, Y., Zhang, Y., Zhang, Y., Zhang, Y., Zhang, Y., Zhang, Y., Zhang, Y., Zhang, Z., Zhang, Z., Zhao, B., Zhao, D., Zhao, F., Zhao, G., Zhao, H., Zhao, H., Zhao, H., Zhao, J., Zhao, J., Zhao, L., Zhao, L., Zhao, L., Zhao, Q., Zhao, Q., Zhao, W., Zhao, W., Zhao, W., Zhao, X., Zhao, X., Zhao, X., Zhao, X., Zhao, X., Zhao, Y., Zhao, Y., Zheng, S., Zheng, X., Zhi, L., Zhong, H., Zhong, Q., Zhong, X., Zhong, Y., Zhou, J., Zhou, J., Zhou, K., Zhou, L., Zhou, L., Zhou, N., Zhou, S., Zhou, S., Zhou, T., Zhou, W., Zhou, W., Zhou, W., Zhou, X., Zhou, Y., Zhou, Y., Zhou, Z., Zhou, Z., Zhu, B., Zhu, J., Zhu, J., Zhu, M., Zhu, Y., Zong, D., Zuo, H., & Zuo, Z.
- Affiliations
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Venue
- The Lancet
- Publisher
- Elsevier BV
- Published
- 2024-07
- Volume
- 404
- Issue
- 10449
- Pages
- 245-255
- ISSN
- 0099-5355 (ISSN-L)
- 0140-6736
- OpenAlex
- W4400066882
- Cited by
- 258
- References
- 29
- Citations by year
- 2026: 105 · 2025: 133 · 2024: 20
- FWCI
- 77.61
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- Locations
- The Lancet (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Servier
- University of Oxford
- National Key Research and Development Program of China (2018YFC1312400, 2018YFC1312401, 2018YFC1312404)
- Tulane University
- Capital Medical University
- Ministry of Science and Technology of the People's Republic of China
- Chinese Academy of Medical Sciences (NCRC2021001)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Blood Pressure and Hypertension Studies
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Disease Prevention
- Health Sciences › Nursing › Nutrition and Dietetics › Sodium Intake and Health
- Keywords
- intensive blood pressure lowering, systolic blood pressure target, high cardiovascular risk, diabetes mellitus, stroke history, cardiovascular events, myocardial infarction, syncope, antihypertensive therapy, China, primary prevention of cardiovascular disease, secondary stroke prevention, revascularization, stroke recurrence, cardiovascular mortality
- MeSH terms
- Heart Disease Risk Factors, Aged, Antihypertensive Agents, Blood Pressure, Cardiovascular Diseases, China, Diabetes Mellitus, Female, Humans, Hypertension, Male, Middle Aged, Myocardial Infarction, Treatment Outcome, Stroke
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