The DOI matches its Crossref record; 137 of the 137 references it cites were found in a registry or an index.
Osteoarthritis
Open accessAbstract
Osteoarthritis is a heterogeneous disorder that is increasingly prevalent largely due to aging and obesity, resulting in a major disease burden worldwide. Knowledge about the underlying aetiology has improved, with increased understanding of the role of genetic factors, the microbiome, and existence of different pain mechanisms. However, this knowledge has not yet been translated into new treatment options. New evidence has questioned the efficacy of recommended treatments, such as therapeutic exercise programmes and the focus on weight loss, but managing obesity and maintaining activity remain important for the prevention and management of osteoarthritis. Approaches should consider individual and cultural preferences and resource availability to increase patient and community engagement, and optimise outcomes worldwide. Most of the focus has been on established osteoarthritis where management is primarily directed at relieving symptoms. The search for the much needed effective treatments that improve both symptoms and structure, often referred to as disease-modifying osteoarthritic drugs, is ongoing. Promising data indicate that targeting inflammation is effective in hand osteoarthritis.
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Cites
Altman, R., Asch, E., Bloch, D., Bole, G., Borenstein, D., Brandt, K., Christy, W., Cooke, T. D., Greenwald, R., Hochberg, M., et al. (1986) · Arthritis & Rheumatism · doi:10.1002/art.1780290816 · Cited by 6,777
Raja, S. N., Carr, D. B., Cohen, M., Finnerup, N. B., Flor, H., Gibson, S., Keefe, F. J., Mogil, J. S., Ringkamp, M., Sluka, K. A., et al. (2020) · Pain · doi:10.1097/j.pain.0000000000001939 · Cited by 5,223
OARSI guidelines for the non-surgical management of knee, hip, and polyarticular osteoarthritis
Bannuru, R. R., Osani, M. C., Vaysbrot, E. E., Arden, N. K., Bennell, K., Bierma-Zeinstra, S. M. A., Kraus, V. B., Lohmander, L. S., Abbott, J. H., Bhandari, M., et al. (2019) · Osteoarthritis and Cartilage · doi:10.1016/j.joca.2019.06.011 · Cited by 3,542
Steinmetz, J. D., Culbreth, G. T., Haile, L. M., Rafferty, Q., Lo, J., Fukutaki, K. G., Cruz, J. A., Smith, A. E., Vollset, S. E., Brooks, P. M., et al. (2023) · The Lancet Rheumatology · doi:10.1016/s2665-9913(23)00163-7 · Cited by 2,053
Self-citationKolasinski, S. L., Neogi, T., Hochberg, M. C., Oatis, C., Guyatt, G., Block, J., Callahan, L., Copenhaver, C., Dodge, C., Felson, D., et al. (2020) · Arthritis & Rheumatology · doi:10.1002/art.41142 · Cited by 1,965
Kwame, A., & Petrucka, P. M. (2021) · BMC Nursing · doi:10.1186/s12912-021-00684-2 · Cited by 1,067
Epidemiology of osteoarthritis
Allen, K. D., Thoma, L. M., & Golightly, Y. M. (2022) · Osteoarthritis and Cartilage · doi:10.1016/j.joca.2021.04.020 · Cited by 929
Evans, J. T., Walker, R. W., Evans, J. P., Blom, A. W., Sayers, A., & Whitehouse, M. R. (2019) · The Lancet · doi:10.1016/s0140-6736(18)32531-5 · Cited by 823
The burden of OA-health services and economics
Leifer, V. P., Katz, J. N., & Losina, E. (2022) · Osteoarthritis and Cartilage · doi:10.1016/j.joca.2021.05.007 · Cited by 727
Evans, J. T., Evans, J. P., Walker, R. W., Blom, A. W., Whitehouse, M. R., & Sayers, A. (2019) · The Lancet · doi:10.1016/s0140-6736(18)31665-9 · Cited by 629
Cited by
Mallia, I., Fioravanti, A., & Guiducci, S. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms262110408 · Cited by 14
Metadata
- Authors
- Kloppenburg, M., Namane, M., & Cicuttini, F.
- Venue
- The Lancet
- Publisher
- Elsevier BV
- Published
- 2025-01
- Volume
- 405
- Issue
- 10472
- Pages
- 71-85
- ISSN
- 0099-5355 (ISSN-L)
- 0140-6736
- OpenAlex
- W4406065270
- Cited by
- 280
- References
- 137
- FWCI
- 176.74
- Type
- journal article
- Language
- en
- Open access
- green
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- Kloppenburg, M., Namane, M., & Cicuttini, F. (2025). Osteoarthritis. The Lancet. https://doi.org/10.1016/s0140-6736(24)02322-5
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
