Diagnosis of the adrenogenital syndrome before birth
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Since the mid-1980s, prenatal treatment with high doses of dexamethasone has been proposed for pregnant women with a fetus at risk for classic CAH using a protocol of 20 μg/kg/day, maximum 1.5 mg/day, aiming to prevent prenatal virilization of the external genitalia in affected girls.
“Since the mid-1980's, prenatal treatment with high doses of Dex has been proposed for to pregnant women with a fetus at risk for classic CAH using a treatment protocol of 20 µg/kg/day, maximum 1.5 mg/day, with the aim of preventing prenatal virilization of the external genitalia in affected girls (313,317,440).”
From Congenital Adrenal Hyperplasia—Current Insights in Pathophysiology, Diagnostics, and Management (2022) · cites this paper as [313]
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Self-citation
- Authors
- Jeffcoate, T. N. A., Fliegner, J. R. H., Russell, S., Davis, J. C., & Wade, A. P.
- ORCID
- Davis, J.C.
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- The Lancet
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- Elsevier BV
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- 1965-09
- Volume
- 286
- Issue
- 7412
- Pages
- 553-555
- ISSN
- 0099-5355 (ISSN-L)
- 0140-6736
- OpenAlex
- W2025783865
- Cited by
- 169
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- 6
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- 2025: 1 · 2024: 1 · 2023: 3 · 2022: 1 · 2021: 2 · 2018: 1 · 2017: 1 · 2016: 2 · 2015: 1 · 2013: 2 · 2012: 5
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- journal article
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- en
- Open access
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- The Lancet (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Sexual Differentiation and Disorders
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Adrenal Hormones and Disorders
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Clinical Biochemistry › Metabolism and Genetic Disorders
- Keywords
- adrenogenital syndrome, congenital adrenal hyperplasia, prenatal diagnosis
- MeSH terms
- Adrenal Hyperplasia, Congenital, Amniotic Fluid, Female, Fetal Diseases, Humans, Infant, Newborn, Pregnancy, Pregnanetriol, 17-Ketosteroids
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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