Cited by 169Sexual Differentiation and DisordersAdrenal Hormones and DisordersMetabolism and Genetic Disorders

Diagnosis of the adrenogenital syndrome before birth

Jeffcoate, T.N.A., Fliegner, J.R.H., Russell, ShonaH., Davis, J.C., Wade, A.P.·1965·The Lancet

Integrity signals

Registry

Crossref · 10.1016/s0140-6736(65)90864-0

Cites

6 of 6 references verified0 citation errors · 0 not checkable

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  • Since the mid-1980s, prenatal treatment with high doses of dexamethasone has been proposed for pregnant women with a fetus at risk for classic CAH using a protocol of 20 μg/kg/day, maximum 1.5 mg/day, aiming to prevent prenatal virilization of the external genitalia in affected girls.

    “Since the mid-1980's, prenatal treatment with high doses of Dex has been proposed for to pregnant women with a fetus at risk for classic CAH using a treatment protocol of 20 µg/kg/day, maximum 1.5 mg/day, with the aim of preventing prenatal virilization of the external genitalia in affected girls (313,317,440).”

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Authors
Jeffcoate, T. N. A., Fliegner, J. R. H., Russell, S., Davis, J. C., & Wade, A. P.
Venue
The Lancet
Publisher
Elsevier BV
Published
1965-09
Volume
286
Issue
7412
Pages
553-555
ISSN
  • 0099-5355 (ISSN-L)
  • 0140-6736
OpenAlex
W2025783865
Cited by
169
References
6
Citations by year
2025: 1 · 2024: 1 · 2023: 3 · 2022: 1 · 2021: 2 · 2018: 1 · 2017: 1 · 2016: 2 · 2015: 1 · 2013: 2 · 2012: 5
FWCI
3.78
Type
journal article
Language
en
Open access
closed
Locations
  • The Lancet (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Sexual Differentiation and Disorders
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Adrenal Hormones and Disorders
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Clinical Biochemistry › Metabolism and Genetic Disorders
Keywords
adrenogenital syndrome, congenital adrenal hyperplasia, prenatal diagnosis
MeSH terms
Adrenal Hyperplasia, Congenital, Amniotic Fluid, Female, Fetal Diseases, Humans, Infant, Newborn, Pregnancy, Pregnanetriol, 17-Ketosteroids

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