The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
Clinical application of apolipoprotein E genotyping to Alzheimer's disease
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In the citing paper
“In contrast, the e 4 allele appears to be harmful, increasing the risk of Alzheimer's disease and hastening the onset of dementia.2,5”
From Preclinical Evidence of Alzheimer's Disease in Persons Homozygous for the ε4 Allele for Apolipoprotein E (1996) · cites this paper as [5]
In the citing paper
“the e4 allele has been associated with an increased risk of Alzheimer's disease, 1-7”
From Preclinical Evidence of Alzheimer's Disease in Persons Homozygous for the ε4 Allele for Apolipoprotein E (1996) · cites this paper as [5]
In the citing paper
“a younger age at the onset of dementia, 2,5”
From Preclinical Evidence of Alzheimer's Disease in Persons Homozygous for the ε4 Allele for Apolipoprotein E (1996) · cites this paper as [5]
In the citing paper
“an older age at the onset of dementia, 5”
From Preclinical Evidence of Alzheimer's Disease in Persons Homozygous for the ε4 Allele for Apolipoprotein E (1996) · cites this paper as [5]
Citations
Cites
Protective effect of apolipoprotein E type 2 allele for late onset Alzheimer disease
Corder, E. H., Saunders, A. M., Risch, N. J., Strittmatter, W. J., Schmechel, D. E., Gaskell, P. C., Rimmler, J. B., Locke, P. A., Conneally, P. M., Schmader, K. E., et al. (1994) · Nature Genetics · doi:10.1038/ng0694-180 · Cited by 1,920
Self-citationApolipoprotein E4 allele in a population–based study of early–onset Alzheimer's disease
van Duijn, C. M., de Knijff, P., Cruts, M., Wehnert, A., Havekes, L. M., Albert Hofman, D., & Broeckhoven, C. V. (1994) · Nature Genetics · doi:10.1038/ng0594-74 · Cited by 459
ApoE–ε4 and early–onset Alzheimer's
Okuizumi, K., Onodera, O., Tanaka, H., Kobayashi, H., Tsuji, S., Takahashi, H., Oyanagi, K., Seki, K., Tanaka, M., Naruse, S., et al. (1994) · Nature Genetics · doi:10.1038/ng0594-10b · Cited by 132
Apolipoprotein E and Alzheimer's disease
Scott, J. (1993) · The Lancet · doi:10.1016/0140-6736(93)91704-p · Cited by 40
Research works printed but not linked: 1
- Mihill, 1993, Test for "Alzheimer's timebomb" prompts social risk warning, Guardian
Cited by
Sorted by citations
Items 101–125 of 125
Kimura, M., Matsushita, S., Arai, H., Matsui, T., Yuzuriha, T., & Higuchi, S. (2000) · Journal of Neural Transmission · doi:10.1007/s007020070008 · Cited by 6
“The presence of this allele decreases the mean age at onset for late-onset AD in a dose-dependent manner (Roses et al., 1994; Strittmatter and Roses, 1996).”
BackgroundPotential therapeutic targets for Alzheimer’s disease
McKeon‐O'Malley, C., Saunders, A. J., Bush, A. I., & Tanzi, R. E. (1998) · Emerging Therapeutic Targets · doi:10.1517/14728222.2.2.157 · Cited by 6
Self-citationCacabelos, R. (2014) · Journal of Postgenomics Drug & Biomarker Development · doi:10.4172/2153-0769.1000e129 · Cited by 4
Etiology, Genetics, and Pathogenesis of Alzheimer's Disease
McKeon‐O'Malley, C., & Tanzi, R. E. (2001) · Elsevier eBooks · doi:10.1016/b978-012351830-9/50024-x · Cited by 3
Putative Risk Factors for Alzheimer's Disease
Mayeux, R. P. (1996) · Informa Healthcare eBooks · doi:10.1201/9781420048407.ch4 · Cited by 2
Shorter Telomere Length in Individuals with Neurocognitive Disorder and APOE ε4 Genotype
Mejía-Ortiz, P., Mendoza, A. D. G., Villanueva, R. R., Ramírez, S. L., Sánchez, R. G., Fernández, T., Sigg-Alonso, J., & Nicolini, H. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26104577 · Cited by 1
“A few years later, Allen Roses et al. (1994) established a connection to Alzheimer’s disease [12].”
[Apolipoprotein E4 and Alzheimer's disease].
Mori, S. (2001) · PubMed · Cited by 1
Personalised medicine – a revolution in healthcare
Hedgecoe, A. M. (2004) · Cambridge University Press eBooks · doi:10.1017/cbo9780511489136.001 · Cited by 1
Ethnic Variation in the Association Between APOE-ε4 and Alzheimer’s Disease: A Follow-up Study
Maestre, G. E., Schofield, P. W., Chun, M. R., Tang, M. ‐., Tycko, B., & Mayeux, R. P. (1996) · Springer eBooks · doi:10.1007/978-3-642-80109-9_15 · Cited by 1
Role of Mitochondria in Alzheimer ́s Disease
Ortiz, G. G., Pacheco-Moisés, F. P., García-Trejo, J. D. J., Rocio, E., Miguel, A., Jose, A., Irma, E., Arias‐Merino, E. D., & de la Ros, A. C. (2011) · InTech eBooks · doi:10.5772/16713
Bibliography NIA/AlzA Conference on Apolipoprotein E Genotyping in Alzheimer's Disease
Kwon, Y. J., Tsai, J., & Relkin, N. R. (1996) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1996.tb32609.x
Research, industry and pharmacogenetic literacy
Hedgecoe, A. M. (2004) · Cambridge University Press eBooks · doi:10.1017/cbo9780511489136.005
The fourth hurdle – cost-effectiveness and the funding of pharmacogenetics
Hedgecoe, A. M. (2004) · Cambridge University Press eBooks · doi:10.1017/cbo9780511489136.007
(2004) · Cambridge University Press eBooks · doi:10.1017/cbo9780511489136.010
Rita, M., & Bueno, P. S. (1997)
Clinical resistance to Alzheimer's pharmacogenetics
Hedgecoe, A. M. (2004) · Cambridge University Press eBooks · doi:10.1017/cbo9780511489136.004
Disappointment and disclosure in the pharmacogenetic clinic
Hedgecoe, A. M. (2004) · Cambridge University Press eBooks · doi:10.1017/cbo9780511489136.008
Pharmacogenetics, expectation and promissory science
Hedgecoe, A. M. (2004) · Cambridge University Press eBooks · doi:10.1017/cbo9780511489136.002
Genetics, moral risk and professional resistance
Hedgecoe, A. M. (2004) · Cambridge University Press eBooks · doi:10.1017/cbo9780511489136.003
Engineering the clinic – getting personalised medicine into practice
Hedgecoe, A. M. (2004) · Cambridge University Press eBooks · doi:10.1017/cbo9780511489136.006
Mondadori, C. R. A. (2006) · Zurich Open Repository and Archive (University of Zurich) · doi:10.5167/uzh-163345
Direct amplification from various biospecimens using a novel PCR buffer system
양영근 (2007) · YUHSpace (Yonsei University Medical Library)
(1995) · Elsevier eBooks · doi:10.1016/b978-0-08-091700-9.50020-8
Hedgecoe, A. M. (2004) · Cambridge University Press eBooks · doi:10.1017/cbo9780511489136.009
Alzheimer%#x2019;s Disease and Genetically Engineered Animal Models
Borchelt, D., Wong, P. C., Sisodia, S. S., & Price, D. L. (1999) · Springer eBooks · doi:10.1007/978-1-4615-4887-4_9
Metadata
- Authors
- Roses, A., Strittmatter, W., Pericak-Vance, M., Corder, E., Saunders, A., & Schmechel, D.
- Venue
- The Lancet
- Publisher
- Elsevier BV
- Published
- 1994-06
- Volume
- 343
- Issue
- 8912
- Pages
- 1564-1565
- ISSN
- 0099-5355 (ISSN-L)
- 0140-6736
- OpenAlex
- W2049634901
- Cited by
- 125
- References
- 4
- Citations by year
- 2025: 1 · 2023: 1 · 2021: 2 · 2019: 4 · 2018: 1 · 2017: 1 · 2016: 2 · 2014: 2 · 2013: 1
- FWCI
- 11.84
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The Lancet (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Alzheimer's disease research and treatments
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic Associations and Epidemiology
- Keywords
- apolipoprotein E, APOE genotyping, Alzheimer's disease, genetic risk factors, diagnosis
- MeSH terms
- Aged, Aged, 80 and over, Alleles, Alzheimer Disease, Apolipoproteins E, Genotype, Humans, Middle Aged
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