The DOI matches its Crossref record; 9 of the 9 references it cites were found in a registry or an index.
Summing up evidence: one answer is not always enough
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Meta-analysis in clinical trials
DerSimonian, R., & Laird, N. (1986) · Controlled Clinical Trials · doi:10.1016/0197-2456(86)90046-2 · Cited by 39,552
Schulz (1995) · doi:10.1001/jama.1995.03520290060030 · Cited by 5,634
Improving the Quality of Reporting of Randomized Controlled Trials: The CONSORT Statement
Begg, C. (1996) · JAMA · doi:10.1001/jama.1996.03540080059030 · Cited by 3,127
Quantitative Synthesis in Systematic Reviews
Lau, J., Ioannidis, J. P. A., & Schmid, C. H. (1997) · Annals of Internal Medicine · doi:10.7326/0003-4819-127-9-199711010-00008 · Cited by 2,517
Self-citationPublication bias and clinical trials
Dickersin, K., Chan, S., Chalmersx, T. C., Sacks, H. S., & Smith, H. (1987) · Controlled Clinical Trials · doi:10.1016/0197-2456(87)90155-3 · Cited by 715
Trial of Calcium to Prevent Preeclampsia
Levine, R. J., Hauth, J. C., Curet, L. B., Sibai, B. M., Catalano, P. M., Morris, C. D., DerSimonian, R., Esterlitz, J. R., Raymond, E. G., Bild, D. E., et al. (1997) · New England Journal of Medicine · doi:10.1056/nejm199707103370201 · Cited by 634
Bayesian approaches to random-effects meta-analysis: a comparative study
Smith, T. C., Spiegelhalter, D. J., & Thomas, A. (1995) · Statistics in Medicine · doi:10.1002/sim.4780142408 · Cited by 568
Large Trials vs Meta-analysis of Smaller Trials: How Do Their Results Compare?
Cappelleri, J. C. (1996) · JAMA · doi:10.1001/jama.1996.03540160054033 · Cited by 336
Invited commentary: benefits of heterogeneity in meta-analysis of data from epidemiologic studies
Berlin, J. A. (1995) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a117645 · Cited by 191
Research works printed but not linked: 38
- Chalmers, 1993, Meta-analysis stimulus for changes in clinical trials, Stat Meth Med Res, 2, 161, 10.1177/096228029300200204 · DOI
- Antman, 1992, A comparison of results of meta-analyses of randomized controlled trials and recommendations of clinical experts: treatments for myocardial infarction, JAMA, 268, 240, 10.1001/jama.1992.03490020088036 · DOI · Paper page
- Teo, 1991, Effect of intravenous magnesium in suspected acute myocardial infarction: overview of randomised trials, BMJ, 303, 1499, 10.1136/bmj.303.6816.1499 · DOI
- Sacks, 1990, Endoscopic hemostasis: an effective therapy for bleeding peptic ulcers, JAMA, 264, 494, 10.1001/jama.1990.03450040090037 · DOI
- Ioannidis, 1996, Impact of epidemic and individual heterogeneity on the population distribution of disease progression rates: an example from patient populations in trials of human immunodeficiency virus infection, Am J Epidemiol, 144, 1074, 10.1093/oxfordjournals.aje.a008881 · DOI
- Topol, 1992, Answers to complex questions cannot be derived from “simple” trials, Br Heart J, 68, 348, 10.1136/hrt.68.10.348 · DOI
- Anello, 1995, Exploratory or analytic meta-analysis: should we distinguish between them?, J Clin Epidemiol, 48, 109, 10.1016/0895-4356(94)00084-4 · DOI
- Naylor, 1996, The case for failed meta-analyses, J Eval Clin Pract, 1, 127, 10.1111/j.1365-2753.1995.tb00018.x · DOI
- Ioannidis, 1996, On meta-analyses of meta-analyses, Lancet, 348, 756, 10.1016/S0140-6736(05)65647-4 · DOI
- Woods, 1992, Intravenous magnesium sulphate in suspected acute myocardial infarction: results of the second Leicester Intravenous Magnesium Intervention Trial (LIMIT-2), Lancet, 339, 1553, 10.1016/0140-6736(92)91828-V · DOI · Paper page
- 1995, ISIS-4: A randomised factorial trial assessing early oral captopril, oral mononitrate, and intravenous magnesium sulphate in 58 050 patients with suspected acute myocardial infarction, Lancet, 345, 669, 10.1016/S0140-6736(95)90865-X · DOI
- 1994, effects of lisinopril and transdermal glyceryl trinitrate singly and together on 6-week mortality and ventricular function after acute myocardial infarction, Lancet, 343, 1115
- 1994, CLASP: a randomised trial of low-dose aspirin for the prevention and treatment of pre-eclampsia among 9364 pregnant women, Lancet, 343, 619, 10.1016/S0140-6736(94)92633-6 · DOI · Paper page
- Bucher, 1996, Effect of calcium supplementation on pregnancy-induced hypertension and preeclampsia: a meta-analysis of randomized controlled trials, JAMA, 275, 1113, 10.1001/jama.1996.03530380055031 · DOI
- Villar, 1995, Predictive ability of meta-analyses of randomised controlled trials, Lancet, 345, 772, 10.1016/S0140-6736(95)90646-0 · DOI
- Lelorier, 1997, Discrepancies between meta-analyses and subsequent large randomized, controlled trials, N Engl J Med, 337, 536, 10.1056/NEJM199708213370806 · DOI
- JP Ioannidis JC Cappelleri J Lau Large trials and meta-analyses. N Engl J Med (in press).
- Berlin, 1994, Advantages and limitations of meta-analytic regressions of clinical trials data, Online J Curr Clin Trials, 134
- Smith, 1993, Cholesterol lowering and mortality: the importance of considering initial level of risk, BMJ, 306, 1367, 10.1136/bmj.306.6889.1367 · DOI
- Boissel, 1993, An effect model for the assessment of drug benefit: example of antiarrhythmic drugs in postmyocardial infarction patients, J Cardiovasc Pharmacol, 22, 356, 10.1097/00005344-199309000-00003 · DOI
- Ioannidis, 1997, Clinical efficacy of antiretroviral changes in treatment-experienced HIV infected patients: a meta-analysis, Online J Curr Clin Trials, 204
- Cappelleri, 1995, Efficacy and safety of different aspirin dosages on vascular diseases; a meta-regression analysis, Online J Curr Clin Trials, 174
- Ioannidis, 1996, A metaanalysis of the relative efficacy and toxicity of P carinii prophylactic regimens, Arch Intern Med, 156, 177, 10.1001/archinte.1996.00440020081010 · DOI
- Morgenstem, 1982, Uses of ecologic analysis in epidemiologic research, Am J Public Health, 72, 1336, 10.2105/AJPH.72.12.1336 · DOI · Paper page
- Yusuf, 1984, Why do we need some large, simple, randomized trials?, Stat Med, 3, 409, 10.1002/sim.4780030421 · DOI · Paper page
- Stewart, 1995, Practical methodology of meta-analyses (overviews) using updated individual patient data: Cochrane Working Group, Stat Med, 14, 2057, 10.1002/sim.4780141902 · DOI · Paper page
- 1995, Effects of radiotherapy and surgery in early breast cancer: an overview of the randomized trials, N Engl J Med, 333, 1444, 10.1056/NEJM199511303332202 · DOI · Paper page
- McIntosh, 1996, The population risk as an explanatory variable in research synthesis of clinical trials, Stat Med, 15, 1713, 10.1002/(SICI)1097-0258(19960830)15:16<1713::AID-SIM331>3.0.CO;2-D · DOI
- Senn, 1994, Importance of trends in the interpretation of an overall odds ratio the meta-analysis of clinical trials, Stat Med, 13, 293, 10.1002/sim.4780130310 · DOI
- Sharp, 1996, The relation between treatment benefit and underlying risk in meta-analysis, BMJ, 313, 735, 10.1136/bmj.313.7059.735 · DOI
- CH Schmid J Lau M McIntosh JC Cappelleri An empirical study of the effect of the control rate as a predictor of treatment efficacy in metaanalysis of clinical trials. Stat Med (in press).
- Ioannidis, 1997, The impact of high risk patients on the results of clinical trials, J Clin Epidemiol, 50, 1089, 10.1016/S0895-4356(97)00149-2 · DOI
- Woods, 1995, Mega-trials and management of acute myocardial infarction, Lancet, 346, 611, 10.1016/S0140-6736(95)91440-4 · DOI
- Rubin, 1992, Meta-analysis: literature synthesis or effect-size surface estimation?, J Educ Stat, 17, 363, 10.2307/1165129 · DOI
- Glasziou, 1995, An evidence based approach to individualising treatment, BMJ, 311, 1356, 10.1136/bmj.311.7016.1356 · DOI
- Moher, 1995, Meta-analysis of randomized controlled trials: a concern for standards, JAMA, 274, 1962, 10.1001/jama.1995.03530240072044 · DOI
- Chalmers, 1996, Changes in clinical trials mandated by the advent of meta-analysis, Stat Med, 15, 1263, 10.1002/(SICI)1097-0258(19960630)15:12<1263::AID-SIM305>3.0.CO;2-K · DOI
- Lau, 1995, Cumulative meta-analysis builds evidence for exemplary medical care, J Clin Epidemiol, 48, 45, 10.1016/0895-4356(94)00106-Z · DOI
Cited by
Liberati, A., Altman, D. G., Tetzlaff, J., Mulrow, C., Gøtzsche, P. C., Ioannidis, J. P. A., Clarke, M., Devereaux, P. J., Kleijnen, J., & Moher, D. (2009) · PLoS Medicine · doi:10.1371/journal.pmed.1000100 · Cited by 28,164
Self-citationLiberati, A., Altman, D. G., Tetzlaff, J., Mulrow, C., Gotzsche, P. C., Ioannidis, J. P. A., Clarke, M., Devereaux, P. J., Kleijnen, J., & Moher, D. (2009) · BMJ · doi:10.1136/bmj.b2700 · Cited by 17,648
Self-citationLiberati, A., Altman, D. G., Tetzlaff, J., Mulrow, C., Gøtzsche, P. C., Ioannidis, J. P. A., Clarke, M., Devereaux, P. J., Kleijnen, J., & Moher, D. (2009) · Journal of Clinical Epidemiology · doi:10.1016/j.jclinepi.2009.06.006 · Cited by 10,578
Self-citationLiberati, A., Altman, D. G., Tetzlaff, J., Mulrow, C., Gøtzsche, P. C., Ioannidis, J. P. A., Clarke, M., Devereaux, P. J., Kleijnen, J., & Moher, D. (2009) · Annals of Internal Medicine · doi:10.7326/0003-4819-151-4-200908180-00136 · Cited by 10,349
Self-citationDevelopment of AMSTAR: A measurement tool to assess the methodological quality of systematic reviews
Shea, B. J., Grimshaw, J. M., Wells, G. A., Boers, M., Andersson, N., Hamel, C., Porter, A. C., Tugwell, P., Moher, D., & Bouter, L. M. (2007) · BMC Medical Research Methodology · doi:10.1186/1471-2288-7-10 · Cited by 4,374
Metadata
- Authors
- Lau, J., Ioannidis, J. P., & Schmid, C. H.
- Venue
- The Lancet
- Publisher
- Elsevier BV
- Published
- 1998-01
- Volume
- 351
- Issue
- 9096
- Pages
- 123-127
- ISSN
- 0099-5355 (ISSN-L)
- 0140-6736
- OpenAlex
- W2018152980
- Cited by
- 655
- References
- 9
- FWCI
- 50.56
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.elsevier.com/tdm/userlicense/1.0/ (tdm)
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Summing up evidence: one answer is not always enough. https://app.cochat.ai/papers/10.1016/s0140-6736(97)08468-7
- The paper
- Lau, J., Ioannidis, J. P., & Schmid, C. H. (1998). Summing up evidence: one answer is not always enough. The Lancet. https://doi.org/10.1016/s0140-6736(97)08468-7
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.