The DOI matches its Crossref record.
Starch-based biodegradable hydrogels with potential biomedical applications as drug delivery systems
Abstract
The design and preparation of novel biodegradable hydrogels developed by the free radical polymerization of acrylamide and acrylic acid, and some formulations with bis-acrylamide, in the presence of a corn starch/ethylene-co-vinyl alcohol copolymer blend (SEVA-C), is reported. The redox system benzoyl peroxide (BPO) and 4-dimethylaminobenzyl alcohol (DMOH) initiated the polymerization at room temperature. Xerogels were characterized by 1H NMR and FTIR spectroscopies. Swelling studies were performed as a function of pH in different buffer solutions determining the water-transport mechanism that governs the swelling behaviour. Degradation studies of the hydrogels were performed in simulated physiological solutions for time up to 90 days, determining the respective weight loss, and analyzing the solution residue by 1H NMR. The mechanical properties of the xerogels were characterized by tensile and compressive tests, as well as by dynamo-mechanical analysis (DMA). Dynamo-mechanical parameters are also reported for hydrated samples.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
Biomedical applications of hydrogels: A review of patents and commercial products
Caló, E., & Khutoryanskiy, V. V. (2015) · European Polymer Journal · doi:10.1016/j.eurpolymj.2014.11.024 · Cited by 2,634
Responsive polymers in controlled drug delivery
Bajpai, A. K., Shukla, S. K., Bhanu, S., & Kankane, S. (2008) · Progress in Polymer Science · doi:10.1016/j.progpolymsci.2008.07.005 · Cited by 1,391
Design and applications of interpenetrating polymer network hydrogels. A review
Dragan, E. S. (2014) · Chemical Engineering Journal · doi:10.1016/j.cej.2014.01.065 · Cited by 992
Electroconductive hydrogels: Synthesis, characterization and biomedical applications
Guiseppi-Elie, A. (2010) · Biomaterials · doi:10.1016/j.biomaterials.2009.12.052 · Cited by 646
Sobral, J. M., Caridade, S. G., Sousa, R. A., Mano, J. F., & Reis, R. L. (2011) · Acta Biomaterialia · doi:10.1016/j.actbio.2010.11.003 · Cited by 561
Self-citation
Metadata
- Authors
- Elvira, C., Mano, J. F., San Román, J., & Reis, R. L.
- Venue
- Biomaterials
- Publisher
- Elsevier BV
- Published
- 2002-05
- Volume
- 23
- Issue
- 9
- Pages
- 1955-1966
- ISSN
- 0142-9612 (ISSN-L)
- OpenAlex
- W1990044730
- Cited by
- 357
- References
- 0
- FWCI
- 6.18
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Starch-based biodegradable hydrogels with potential biomedical applications as drug delivery systems. https://app.cochat.ai/papers/10.1016/s0142-9612(01)00322-2
- The paper
- Elvira, C., Mano, J. F., San Román, J., & Reis, R. L. (2002). Starch-based biodegradable hydrogels with potential biomedical applications as drug delivery systems. Biomaterials. https://doi.org/10.1016/s0142-9612(01)00322-2
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
