Cited by 485Mercury impact and mitigation studiesHeavy Metal Exposure and ToxicityEnvironmental Toxicology and Ecotoxicology

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Cases of mercury exposure, bioavailability, and absorption

Gochfeld, Michael·2003·Ecotoxicology and Environmental Safety

DOI 10.1016/s0147-6513(03)00060-5

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Abstract

Mercury is a unique element that, unlike many metals, has no essential biological function. It is liquid at room temperature and is 13.6 times heavier than water. Its unique physical properties have been exploited for a variety of uses such as in mercury switches, thermostats, thermometers, and other instruments. Its ability to amalgamate with gold and silver are used in mining these precious metals and as a dental restorative. Its toxic properties have been exploited for medications, preservatives, antiseptics, and pesticides. For these reasons there have been many industrial uses of mercury, and occupational exposures of workers and industrial emissions and effluents contaminating air, water, soil, and ultimately food chains have long been a matter of great public health concern. This paper examines briefly six cases representing various forms of exposure to different species of mercury, and indicates the methodological issues in estimating exposure, bioavailability and absorption; these cases include Minamata disease in Japan, organic mercury poisoning in Iraq, methylmercury (MeHg) exposure in the Amazon, dimethylmercury (PMM) in the laboratory, an elemental mercury spill in Cajamarca, Peru, and a mercury-contaminated building in Hoboken, NJ, USA. Other scenarios that are not described include occupational exposure to mercury salts, mercurial preservatives in vaccines, cultural and ritualistic uses of mercury, and mercury in dental amalgams.

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Toxicological Effects of Methylmercury
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Authors: Gochfeld, M.
Affiliations: Rutgers, The State University of New Jersey (US)
Corresponding author: Gochfeld, Michael
ORCID: Gochfeld, Michael
Venue: Ecotoxicology and Environmental Safety
Publisher: Elsevier BV
Published: 2003-09
Volume: 56
Issue: 1
Pages: 174-179
ISSN: 0147-6513 (ISSN-L)
DOI: 10.1016/s0147-6513(03)00060-5
OpenAlex: W2087082909
Cited by: 485
References: 20
Citations by year: 2026: 2 · 2025: 10 · 2024: 19 · 2023: 20 · 2022: 26 · 2021: 33 · 2020: 25 · 2019: 19 · 2018: 22 · 2017: 16 · 2016: 21 · 2015: 25 · 2014: 36 · 2013: 19 · 2012: 34
FWCI: 8.85
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Ecotoxicology and Environmental Safety (publishedVersion)
PubMed (publishedVersion)
Topics: Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Mercury impact and mitigation studies
Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Heavy Metal Exposure and Toxicity
Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Environmental Toxicology and Ecotoxicology
Keywords: mercury exposure, mercury toxicity, bioavailability, mercury uptake, Minamata disease, organic mercury poisoning, methylmercury, dimethylmercury, occupational mercury exposure, mercury contamination, exposure assessment
MeSH terms: Absorption, Accidents, Animals, Biological Availability, Brazil, Environmental Exposure, Fishes, Humans, Iraq, Japan, Mercury, Methylmercury Compounds, Occupational Exposure, Mercury Poisoning, Nervous System, Food Chain

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