The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Nitric oxide and carbon monoxide: parallel roles as neural messengers
Open accessAbstract
Nitric oxide is now appreciated to be a molecule with important signaling functions in the body. The purification and cloning of the first NO synthesizing enzyme, NO synthase (NOS), from brain has led to the characterization of the roles of NO in normal physiology and in pathogenic states. NO synthesis is regulated in a complex manner, involving the association of activatory and inhibitory proteins. The body appears to use at least one other, highly related gas in a signaling function, carbon monoxide (CO). The enzyme responsible for CO biosynthesis in brain, heme oxygenase-2 (HO2), is rapidly regulated by neurotransmitter stimulation. The role for CO as neurotransmitter is suggested by the altered intestinal motility in mice harboring a genomic deletion of HO2.
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Cites
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Cited by
Carbon Monoxide: Endogenous Production, Physiological Functions, and Pharmacological Applications
Wu, L., & Wang, R. (2005) · Pharmacological Reviews · doi:10.1124/pr.57.4.3 · Cited by 962
Heme oxygenase: colors of defense against cellular stress
Otterbein, L. E., & Choi, A. M. K. (2000) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.2000.279.6.l1029 · Cited by 870
Riess, J. G. (2001) · Chemical Reviews · doi:10.1021/cr970143c · Cited by 773
Hydrogen Sulfide Induces Cyclic AMP and Modulates the NMDA Receptor
Kimura, H. (2000) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1999.1915 · Cited by 347
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Metadata
- Authors
- Snyder, S. H., Jaffrey, S. R., & Zakhary, R.
- Venue
- Brain Research Reviews
- Publisher
- Elsevier BV
- Published
- 1998-05
- Volume
- 26
- Issue
- 2-3
- Pages
- 167-175
- ISSN
- 0165-0173 (ISSN-L)
- OpenAlex
- W1522191426
- Cited by
- 237
- References
- 5
- FWCI
- 9.12
- Type
- journal article
- Language
- en
- Open access
- hybrid
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