Cited by 42T-cell and B-cell ImmunologyPsoriasis: Treatment and PathogenesisImmunotoxicology and immune responses

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In vitro generation of IL-10-producing regulatory CD4+ T cells is induced by immunosuppressive drugs and inhibited by Th1- and Th2-inducing cytokines

O'Garra, Anne, Barrat, Franck J·2003·Immunology Letters

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Crossref · 10.1016/s0165-2478(02)00239-0

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  • Signaling through NR3C1 varies depending on T cell phenotype; in effector T cells, DEXA inhibits pro-inflammatory cytokine production and proliferation.

    “Signaling through NR3C1 varies depending on T cell phenotype: for example, in effector T cells, DEXA inhibits pro-inflammatory cytokine production and proliferation, potentially reducing harmful inflammation [O’Garra & Barrat, 2003].”

    From Cell signaling pathways discovery from multi-modal data (2025) · cites this paper as O’Garra & Barrat, 2003

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Research works printed but not linked: 39

  1. O'Garra, 1998, Cytokines induce the development of functionally heterogeneous T helper cell subsets, Immunity, 8, 275, 10.1016/S1074-7613(00)80533-6 · DOI
  2. Moore, 2001, Interleukin-10 and the interleukin-10 receptor, Annu. Rev. Immunol., 19, 683, 10.1146/annurev.immunol.19.1.683 · DOI · Paper page
  3. Mason, 1998, Control of immune pathology by regulatory T cells, Curr. Opin. immunol., 10, 649, 10.1016/S0952-7915(98)80084-8 · DOI
  4. Maloy, 2001, Regulatory T cells in the control of immune pathology, Nat. Immunol., 2, 816, 10.1038/ni0901-816 · DOI
  5. Lafaille, 1997, Myelin basic protein-specific T helper 2 (Th2) cells cause experimental autoimmune encephalomyelitis in immunodeficient hosts rather than protect them from disease, J. Exp. Med., 186, 307, 10.1084/jem.186.2.307 · DOI
  6. Sakaguchi, 2000, Regulatory T cells: key controllers of immunologic self-tolerance, Cell, 101, 455, 10.1016/S0092-8674(00)80856-9 · DOI
  7. Weiner, 1997, Oral tolerance for the treatment of autoimmune diseases, Annu. Rev. Med., 48, 341, 10.1146/annurev.med.48.1.341 · DOI
  8. Powrie, 1996, A critical role for transforming growth factor-β but not interleukin 4 in the suppression of T helper type 1-mediated colitis by CD45RBlow CD4+ T cells, J. Exp. Med., 183, 2669, 10.1084/jem.183.6.2669 · DOI
  9. Seddon, 2000, The third function of the thymus, Immunol. Today, 21, 95, 10.1016/S0167-5699(99)01559-5 · DOI
  10. Thornton, 1998, CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production, J. Exp. Med., 188, 287, 10.1084/jem.188.2.287 · DOI
  11. Akdis, 1998, Role of interleukin 10 in specific immunotherapy, J. Clin. Invest., 102, 98, 10.1172/JCI2250 · DOI
  12. Grunig, 1997, Interleukin-10 is a natural suppressor of cytokine production and inflammation in a murine model of allergic bronchopulmonary aspergillosis, J. Exp. Med., 185, 1089, 10.1084/jem.185.6.1089 · DOI
  13. Bacchetta, 1994, High levels of interleukin 10 production in vivo are associated with tolerance in SCID patients transplanted with HLA mismatched hematopoietic stem cells, J. Exp. Med., 179, 493, 10.1084/jem.179.2.493 · DOI
  14. Jonuleit, 2000, Induction of Interleukin 10-producing, Nonproliferating CD4+ T Cells with Regulatory Properties by Repetitive Stimulation with Allogeneic Immature Human Dendritic Cells, J. Exp. Med., 192, 1213, 10.1084/jem.192.9.1213 · DOI
  15. Dhodapkar, 2001, Antigen-specific inhibition of effector T cell function in humans after injection of immature dendritic cells, J. Exp. Med., 193, 233, 10.1084/jem.193.2.233 · DOI
  16. Groux, 1997, Generation of a novel regulatory CD4+ T-cell population, which inhibits antigen-specific T-cell responses, Nature, 389, 737, 10.1038/39614 · DOI
  17. Olivares-Villagomez, 2000, Repertoire requirements of CD4+ T cells that prevent spontaneous autoimmune encephalomyelitis, J. Immunol., 164, 5499, 10.4049/jimmunol.164.10.5499 · DOI
  18. Levings, 2001, IFN-alpha and IL-10 induce the differentiation of human type 1 T regulatory cells, J. Immunol., 166, 5530, 10.4049/jimmunol.166.9.5530 · DOI
  19. Lemire, 1995, Immunosuppressive actions of 1,25-dihydroxyvitamin D3: preferential inhibition of Th1 functions, J. Nutr., 125, 1704S
  20. Wilckens, 1997, Glucocorticoids and immune function: unknown dimensions and new frontiers, Immunol. Today, 18, 418, 10.1016/S0167-5699(97)01111-0 · DOI
  21. Karin, 1998, New twists in gene regulation by glucocorticoid receptor: is DNA binding dispensable?, Cell, 93, 487, 10.1016/S0092-8674(00)81177-0 · DOI
  22. Barrat, 2002, In vitro generation of regulatory T cells is induced by immunosuppressive drugs and inhibited by T helper 1 (Th1)- and Th2-inducing cytokines, J. Exp. Med., 195, 603, 10.1084/jem.20011629 · DOI
  23. Richards, 2000, Glucocorticoids drive human CD8(+) T cell differentiation towards a phenotype with high IL-10 and reduced IL-4, IL-5 and IL-13 production, Eur. J. Immunol., 30, 2344, 10.1002/1521-4141(2000)30:8<2344::AID-IMMU2344>3.0.CO;2-7 · DOI
  24. De Bosscher, 1997, Glucocorticoid-mediated repression of nuclear factor-kappaB-dependent transcription involves direct interference with transactivation, Proc. Natl. Acad. Sci. USA, 94, 13504, 10.1073/pnas.94.25.13504 · DOI
  25. Chen, 2000, Glucocorticoids inhibit calcium- and calcineurin-dependent activation of the human IL-4 promoter, J. Immunol., 164, 825, 10.4049/jimmunol.164.2.825 · DOI
  26. Yu, 1995, Down-regulation of NF-kappa B protein levels in activated human lymphocytes by 1,25-dihydroxyvitamin D3, Proc. Natl. Acad. Sci. USA, 92, 10990, 10.1073/pnas.92.24.10990 · DOI
  27. Alroy, 1995, Transcriptional repression of the interleukin-2 gene by vitamin D3: direct inhibition of NFATp/AP-1 complex formation by a nuclear hormone receptor, Mol. Cell Biol., 15, 5789, 10.1128/MCB.15.10.5789 · DOI
  28. Castro, 2000, Anti-interleukin 10 receptor monoclonal antibody is an adjuvant for T helper cell type 1 responses to soluble antigen only in the presence of lipopolysaccharide, J. Exp. Med., 192, 1529, 10.1084/jem.192.10.1529 · DOI
  29. Glimcher, 2000, Lineage commitment in the immune system: the T helper lymphocyte grows up, Genes Dev., 14, 1693, 10.1101/gad.14.14.1693 · DOI
  30. O'Garra, 2000, The molecular basis of T helper 1 and T helper 2 cell differentiation, Trends Cell Biol., 10, 542, 10.1016/S0962-8924(00)01856-0 · DOI
  31. Zheng, 1997, The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4T cells, Cell, 89, 587, 10.1016/S0092-8674(00)80240-8 · DOI · Paper page
  32. Ouyang, 1998, Inhibition of Th1 development mediated by GATA-3 through an IL-4-independent mechanism, Immunity, 9, 745, 10.1016/S1074-7613(00)80671-8 · DOI
  33. Kim, 1999, The transcription factor c-maf controls the production of IL-4 but not other Th2 cytokines, Immunity, 10, 745, 10.1016/S1074-7613(00)80073-4 · DOI
  34. Szabo, 2000, A novel transcription factor, T-bet, directs Th1 lineage commitment, Cell, 100, 655, 10.1016/S0092-8674(00)80702-3 · DOI · Paper page
  35. Medzhitov, 1997, Innate immunity: the virtues of a nonclonal system of recognition, Cell, 91, 295, 10.1016/S0092-8674(00)80412-2 · DOI · Paper page
  36. Asseman, 1999, An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation, J. Exp. Med., 190, 995, 10.1084/jem.190.7.995 · DOI
  37. Swain, 1991, Transforming growth factor-beta and IL-4 cause helper T cell precursors to develop into distinct effector helper cells that differ in lymphokine secretion pattern and cell surface phenotype, J. Immunol., 147, 2991, 10.4049/jimmunol.147.9.2991 · DOI
  38. Sad, 1994, A single IL-2-secreting precursor CD4 T cell can develop into either a Th1 or Th2 secreting phenotype, J. Immunol., 153, 3514, 10.4049/jimmunol.153.8.3514 · DOI
  39. Heath, 2000, TGF-beta1 downregulates Th2 development and results in decreased IL-4-induced Stat6 activation and GATA-3 expression, Eur. J. Immunol., 30, 2639, 10.1002/1521-4141(200009)30:9<2639::AID-IMMU2639>3.0.CO;2-7 · DOI

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Metadata

Authors
O'Garra, A., & Barrat, F. J.
Affiliations
Dynavax Technologies (United States) (US)
Venue
Immunology Letters
Publisher
Elsevier BV
Published
2003-01
Volume
85
Issue
2
Pages
135-139
ISSN
0165-2478 (ISSN-L)
OpenAlex
W2065427225
Cited by
42
References
1
Citations by year
2025: 1 · 2022: 1 · 2021: 1 · 2018: 2 · 2014: 2 · 2012: 2
FWCI
0.44
Type
journal article
Language
en
Open access
closed
Locations
  • Immunology Letters (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Life Sciences › Immunology and Microbiology › Immunology › T-cell and B-cell Immunology
  • Life Sciences › Immunology and Microbiology › Immunology › Psoriasis: Treatment and Pathogenesis
  • Life Sciences › Immunology and Microbiology › Immunology › Immunotoxicology and immune responses
Keywords
regulatory T cells, IL-10, CD4+ T cells, immunosuppressants, Th1 cytokines, Th2 cytokines, Treg differentiation
MeSH terms
Animals, Cell Differentiation, Cholecalciferol, Dexamethasone, Humans, Immunosuppressive Agents, Signal Transduction, CD4-Positive T-Lymphocytes, Cytokines, Interleukin-10, Th1 Cells, Th2 Cells

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