A Novel Transcription Factor, T-bet, Directs Th1 Lineage Commitment

TH1 and TH2 Cells: Different Patterns of Lymphokine Secretion Lead to Different Functional Properties

Mosmann, T. R., & Coffman, R. L. (1989) · Annual Review of Immunology · doi:10.1146/annurev.iy.07.040189.001045 · Cited by 7,692 · see citing works

Functional diversity of helper T lymphocytes

Abbas, A. K., MURPHY, K. M. M., & Sher, A. (1996) · Nature · doi:10.1038/383787a0 · Cited by 4,383 · see citing works

Development of T _H 1 CD4 ⁺ T Cells Through IL-12 Produced by <i>Listeria</i> -Induced Macrophages

Hsieh, C.-S., Macatonia, S. E., Tripp, C. S., Wolf, S. F., O'Garra, A., & Murphy, K. M. (1993) · Science · doi:10.1126/science.8097338 · Cited by 3,134 · see citing works

The Transcription Factor GATA-3 Is Necessary and Sufficient for Th2 Cytokine Gene Expression in CD4 T Cells

Zheng, W.-P., & Flavell, R. A. (1997) · Cell · doi:10.1016/s0092-8674(00)80240-8 · Cited by 2,384 · see citing works

IL-10 acts on the antigen-presenting cell to inhibit cytokine production by Th1 cells

Fiorentino, D. F., Zlotnik, A., Vieira, P., Mosmann, T. R., Howard, M., Moore, K. W., & O’Garra, A. (1991) · The Journal of Immunology · doi:10.4049/jimmunol.146.10.3444 · Cited by 1,858 · see citing works

Lymphocyte responses and cytokines

Paul, W. E., & Seder, R. A. (1994) · Cell · doi:10.1016/0092-8674(94)90332-8 · Cited by 1,832 · see citing works

Induction of Th1 and Th2 CD4+ T cell responses: the alternative approaches.

Constant, S., & Bottomly, K. (1997) · Annual Review of Immunology · doi:10.1146/annurev.immunol.15.1.297 · Cited by 1,698 · see citing works

Acquisition of lymphokine-producing phenotype by CD4+ T cells

Seder, R. A., & Paul, W. E. (1994) · Annual Review of Immunology · doi:10.1146/annurev.iy.12.040194.003223 · Cited by 1,557 · see citing works

Immune Response in Mice that Lack the Interferon-γ Receptor

Huang, S., Hendriks, W. J. A. J., Althage, A., Hemmi, S., Bluethmann, H., Kamijo, R., Vilček, J., Zinkernagel, R. M., & Aguet, M. (1993) · Science · doi:10.1126/science.8456301 · Cited by 1,551 · see citing works

The IL-4 receptor: signaling mechanisms and biologic functions

Nelms, K., Keegan, A. D., Zamorano, J., Ryan, J. J., & Paul, W. E. (1999) · Annual Review of Immunology · doi:10.1146/annurev.immunol.17.1.701 · Cited by 1,545 · see citing works

Cytokines Induce the Development of Functionally Heterogeneous T Helper Cell Subsets

O’Garra, A. (1998) · Immunity · doi:10.1016/s1074-7613(00)80533-6 · Cited by 1,535 · see citing works

Lymphokine Production by Human T Cells in Disease States

Romagnani, S. (1994) · Annual Review of Immunology · doi:10.1146/annurev.iy.12.040194.001303 · Cited by 1,332 · see citing works

Impaired IL-12 responses and enhanced development of Th2 cells in Stat4-deficient mice

Kaplan, M. H., Sun, Y.-L., Hoey, T., & Grusby, M. J. (1996) · Nature · doi:10.1038/382174a0 · Cited by 1,240 · see citing works

THE INTERLEUKIN-12/INTERLEUKIN-12-RECEPTOR SYSTEM: Role in Normal and Pathologic Immune Responses

Gately, M. K., Renzetti, L. M., Magram, J., STERN, A. S., Adorini, L., Gubler, U., & Presky, D. H. (1998) · Annual Review of Immunology · doi:10.1146/annurev.immunol.16.1.495 · Cited by 1,231 · see citing works

Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells

Thierfelder, W. E., van Deursen, J. M., Yamamoto, K., Tripp, R. A., Sarawar, S. R., Carson, R. T., Sangster, M. Y., Vignali, D. A. A., Doherty, P. C., Grosveld, G. C., et al. (1996) · Nature · doi:10.1038/382171a0 · Cited by 1,181 · see citing works

Mutations in human cause limb and cardiac malformation in Holt-Oram syndrome

Basson, C. T., Bachinsky, D. R., Lin, R. C., Levi, T., Elkins, J. A., Soults, J., Grayzel, D. M., Kroumpouzou, E., Traill, T. A., LeBlanc-Straceski, J., et al. (1997) · Nature Genetics · doi:10.1038/ng0197-30 · Cited by 1,090 · see citing works

Regulation of the Interleukin (IL)-12R β2 Subunit Expression in Developing T Helper 1 (Th1) and Th2 Cells

Szabo, S. J., Dighe, A. S., Gubler, U., & MURPHY, K. M. M. (1997) · The Journal of Experimental Medicine · doi:10.1084/jem.185.5.817 · Cited by 973 · see citing works

Cloning of the T gene required in mesoderm formation in the mouse

Herrmann, B. G., Labeit, S., Poustka, A., King, T. R., & Lehrach, H. R. (1990) · Nature · doi:10.1038/343617a0 · Cited by 839 · see citing works

Inhibition of Th1 Development Mediated by GATA-3 through an IL-4-Independent Mechanism

Ouyang, W., Ranganath, S. H., Weindel, K., Bhattacharya, D., Murphy, T. L., Sha, W. C., & MURPHY, K. M. M. (1998) · Immunity · doi:10.1016/s1074-7613(00)80671-8 · Cited by 778 · see citing works

Modulation of Chromatin Structure Regulates Cytokine Gene Expression during T Cell Differentiation

Agarwal, S., & Rao, A. (1998) · Immunity · doi:10.1016/s1074-7613(00)80642-1 · Cited by 687 · see citing works

The Proto-Oncogene c-maf Is Responsible for Tissue-Specific Expression of Interleukin-4

Ho, I., Hodge, M. R., Rooney, J. W., & Glimcher, L. H. (1996) · Cell · doi:10.1016/s0092-8674(00)81299-4 · Cited by 667 · see citing works

Transcription Factor GATA-3 Is Differentially Expressed in Murine Th1 and Th2 Cells and Controls Th2-specific Expression of the Interleukin-5 Gene

Zhang, D.-H., Cohn, L. E., Ray, P., Bottomly, K., & Ray, A. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.34.21597 · Cited by 665 · see citing works

The interleukin 12 p40 gene promoter is primed by interferon gamma in monocytic cells.

Ma, X., Chow, J. M., Gri, G., Carra, G., Gerosa, F., Wolf, S. F., Dzialo, R., & Trinchieri, G. (1996) · The Journal of Experimental Medicine · doi:10.1084/jem.183.1.147 · Cited by 648 · see citing works

Prolactin induces phosphorylation of Tyr694 of Stat5 (MGF), a prerequisite for DNA binding and induction of transcription.

Gouilleux, F., Wakao, H., Mundt, M., & Groner, B. (1994) · The EMBO Journal · doi:10.1002/j.1460-2075.1994.tb06756.x · Cited by 588 · see citing works

Mutations in human TBX3 alter limb, apocrine and genital development in ulnar-mammary syndrome

Bamshad, M., Lin, R. C., Law, D. J., Watkins, W. S., Krakowiak, P. A., Moore, M. E., Franceschini, P., Lala, R., Holmes, L. B., Gebuhr, T. C., et al. (1997) · Nature Genetics · doi:10.1038/ng0797-311 · Cited by 540 · see citing works

High incidence of spontaneous autoimmune encephalomyelitis in immunodeficient anti-myelin basic protein T cell receptor transgenic mice

Lafaille, J. J., Nagashima, K., Katsuki, M., & Tonegawa, S. (1994) · Cell · doi:10.1016/0092-8674(94)90419-7 · Cited by 532 · see citing works

Structure of the human immune interferon gene

Gray, P. W., & Goeddel, D. V. (1982) · Nature · doi:10.1038/298859a0 · Cited by 519 · see citing works

Generation of polarized antigen-specific CD8 effector populations: reciprocal action of interleukin (IL)-4 and IL-12 in promoting type 2 versus type 1 cytokine profiles.

Croft, M., Carter, L., Swain, S. L., & Dutton, R. W. (1994) · The Journal of Experimental Medicine · doi:10.1084/jem.180.5.1715 · Cited by 514 · see citing works

Cooperative DNA Binding and Sequence-Selective Recognition Conferred by the STAT Amino-Terminal Domain

Xu, X. M., Sun, Y., & Hoey, T. C. (1996) · Science · doi:10.1126/science.273.5276.794 · Cited by 480 · see citing works

Reversibility of T helper 1 and 2 populations is lost after long-term stimulation.

Murphy, E., Shibuya, K., Hosken, N. A., Openshaw, P., Maino, V. C., Davis, K. A., MURPHY, K. M. M., & O’Garra, A. (1996) · The Journal of Experimental Medicine · doi:10.1084/jem.183.3.901 · Cited by 435 · see citing works

Interaction of NF-κB and NFAT with the Interferon-γ Promoter

Sica, A., Dorman, L., Viggiano, V., Cippitelli, M., Ghosh, P., Rice, N. R., & Young, H. A. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.48.30412 · Cited by 430 · see citing works

Developmental commitment to the Th2 lineage by extinction of IL-12 signaling

Szabo, S. J., Jacobson, N. G., Dighe, A. S., Gubler, U., & MURPHY, K. M. M. (1995) · Immunity · doi:10.1016/1074-7613(95)90011-x · Cited by 421 · see citing works

The Transcription Factor c-Maf Controls the Production of Interleukin-4 but Not Other Th2 Cytokines

Kim, J. I., Ho, I., Grusby, M. J., & Glimcher, L. H. (1999) · Immunity · doi:10.1016/s1074-7613(00)80073-4 · Cited by 383 · see citing works

Interleukin 18 together with interleukin 12 inhibits IgE production by induction of interferon-γ production from activated B cells

Yoshimoto, T., Okamura, H., Tagawa, Y., Iwakura, Y., & Nakanishi, K. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.8.3948 · Cited by 380 · see citing works

TCGF (IL 2)-receptor inducing factor(s). I. Regulation of IL 2 receptor on a natural killer-like cell line (YT cells).

Yodoi, J., Teshigawara, K., Nikaido, T., et al. (1985) · The Journal of Immunology · doi:10.4049/jimmunol.134.3.1623 · Cited by 372 · see citing works

Inhibition of allergic inflammation in a murine model of asthma by expression of a dominant-negative mutant of GATA-3.

Zhang, D.-H., Yang, L.-Y., Cohn, L., Parkyn, L., Homer, R. J., Ray, P., & Ray, A. (1999) · Immunity · doi:10.1016/s1074-7613(00)80122-3 · Cited by 364 · see citing works

Multistage Regulation of Th1-Type Immune Responses by the Transcription Factor IRF-1

Taki, S., Sato, T., Ogasawara, K., Fukuda, T., Sato, M., Hida, S., Suzuki, G., Mitsuyama, M., Shin, E.-H., Kojima, S., et al. (1997) · Immunity · doi:10.1016/s1074-7613(00)80443-4 · Cited by 353 · see citing works

Crystallographic structure of the T domain–DNA complex of the Brachyury transcription factor

Müller, C. W., & Herrmann, B. G. (1997) · Nature · doi:10.1038/39929 · Cited by 326 · see citing works

P-Selectin Glycoprotein Ligand-1 (PSGL-1) on T Helper 1 but Not on T Helper 2 Cells Binds to P-Selectin and Supports Migration into Inflamed Skin

Borges, E., Tietz, W., Steegmaier, M., Moll, T., Hallmann, R., Hamann, A., & Vestweber, D. (1997) · Journal of Experimental Medicine · doi:10.1084/jem.185.3.573 · Cited by 311 · see citing works

The T-box genes Tbx4 and Tbx5 regulate limb outgrowth and identity

Rodrı́guez-Esteban, C., Tsukui, T., Yonei‐Tamura, S., Magallon, J., Tamura, K., & Belmonte, J. C. I. (1999) · Nature · doi:10.1038/19769 · Cited by 307 · see citing works

Groucho proteins: transcriptional corepressors for specific subsets of DNA-binding transcription factors in vertebrates and invertebratesPreprint

Fisher, A. L., & Caudy, M. A. (1998) · Genes & Development · doi:10.1101/gad.12.13.1931 · Cited by 294 · see citing works

Interferon Regulatory Factor-1 Is Required for a T Helper 1 Immune Response In Vivo

Lohoff, M. D., Ferrick, D. A., Mittrücker, H., Duncan, G. S., Bischof, S., Röllinghoff, M., & Mak, T. W. (1997) · Immunity · doi:10.1016/s1074-7613(00)80444-6 · Cited by 286 · see citing works

Tbx5 and Tbx4 genes determine the wing/leg identity of limb buds

Takeuchi, J., Koshiba‐Takeuchi, K., Matsumoto, K., Vogel‐Höpker, A., Naitoh-Matsuo, M., Ogura, K., Takahashi, N., Yasuda, K., & Ogura, T. (1999) · Nature · doi:10.1038/19762 · Cited by 267 · see citing works

Identification of cis-acting regulatory elements controlling interleukin-4 gene expression in T cells: roles for NF-Y and NF-ATc.

Szabo, S. J., Gold, J. S., Murphy, T. L., & MURPHY, K. M. M. (1993) · Molecular and Cellular Biology · doi:10.1128/mcb.13.8.4793 · Cited by 240 · see citing works

A subpopulation of B220+ cells in murine bone marrow does not express CD19 and contains natural killer cell progenitors.

Rolink, A. G., ten Boekel, E., Melchers, F., Fearon, D. T., Krop, I. E., & Andersson, J. (1996) · The Journal of Experimental Medicine · doi:10.1084/jem.183.1.187 · Cited by 219 · see citing works

Th1 and Th2 cells

Dong, C., & Flavell, R. A. (2001) · Current Opinion in Hematology · doi:10.1097/00062752-200101000-00009 · Cited by 216 · see citing works

Differentiation of the T helper phenotypes by analysis of the methylation state of the IFN- gamma gene.

Young, H. A., Ghosh, P., Ye, J., Lederer, J. A., Lichtman, A. H., Gerard, J. R., Penix, L. A., Wilson, C. B., Melvin, A. J., McGurn, M. E., et al. (1994) · The Journal of Immunology · doi:10.4049/jimmunol.153.8.3603 · Cited by 204 · see citing works

The Proximal Regulatory Element of the Interferon-γ Promoter Mediates Selective Expression in T Cells

Penix, L. A., Sweetser, M. T., Weaver, W. M., Hoeffler, J. P., Kerppola, T. K., & Wilson, C. B. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.50.31964 · Cited by 195 · see citing works

Rapid retroviral delivery of tetracycline-inducible genes in a single autoregulatory cassette.

Hofmann, A., Nolan, G. P., & Blau, H. M. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.11.5185 · Cited by 187 · see citing works

Polarization of IL-4- and IFN-γ-producing CD4+ T cells following activation of naive CD4+ T cells

Nakamura, T., Kamogawa, Y., Bottomly, K., & Flavell, R. A. (1997) · The Journal of Immunology · doi:10.4049/jimmunol.158.3.1085 · Cited by 180 · see citing works

GATA-3 Significantly Downregulates IFN-γ Production from Developing Th1 Cells in Addition to Inducing IL-4 and IL-5 Levels

Ferber, I., Lee, H., Zonin, F., Heath, V. L., Mui, A., Arai, N., & O’Garra, A. (1999) · Clinical Immunology · doi:10.1006/clim.1999.4718 · Cited by 172 · see citing works

Lineage-specific Requirement for Signal Transducer and Activator of Transcription (Stat)4 in Interferon γ Production from CD4+ Versus CD8+ T Cells

Carter, L., & Murphy, K. M. (1999) · The Journal of Experimental Medicine · doi:10.1084/jem.189.8.1355 · Cited by 170 · see citing works

NF-AT-Driven Interleukin-4 Transcription Potentiated by NIP45

Hodge, M. R., Chun, H. J., Rengarajan, J., Alt, A., Lieberson, R., & Glimcher, L. H. (1996) · Science · doi:10.1126/science.274.5294.1903 · Cited by 132 · see citing works

Brachyury and the T-box genes

Smith, J. (1997) · Current Opinion in Genetics & Development · doi:10.1016/s0959-437x(97)80073-1 · Cited by 131 · see citing works

The Roles of Nuclear Factor of Activated T Cells and Ying-Yang 1 in Activation-induced Expression of the Interferon-γ Promoter in T Cells

Sweetser, M. T., Hoey, T., Sun, Y., et al. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.52.34775 · Cited by 127 · see citing works

Cell surface phenotype of a cloned line of human natural killer cells.

Kornbluth, J., Flomenberg, N., & Dupont, B. (1982) · The Journal of Immunology · doi:10.4049/jimmunol.129.6.2831 · Cited by 126 · see citing works

The Ets transcription factor ERM is Th1-specific and induced by IL-12 through a Stat4-dependent pathway

Ouyang, W., Jacobson, N. G., Bhattacharya, D., Gorham, J. D., Fenoglio, D., Sha, W. C., Murphy, T. L., & MURPHY, K. M. M. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.7.3888 · Cited by 108 · see citing works

Regulation of cytokine gene expression in T helper cell subsets.

Lederer, J. A., Liou, J. S., Todd, M., et al. (1994) · The Journal of Immunology · doi:10.4049/jimmunol.152.1.77 · Cited by 100 · see citing works

IL-4 and IL-13 production in differentiated T helper type 2 cells is not IL-4 dependent

Huang, H., Hu‐Li, J., Chen, H., et al. (1997) · The Journal of Immunology · doi:10.4049/jimmunol.159.8.3731 · Cited by 85 · see citing works

Interleukin-12 Induces Expression of Interferon Regulatory Factor-1 via Signal Transducer and Activator of Transcription-4 in Human T Helper Type 1 Cells

Coccia, E. M., Passini, N., Battistini, A., Pini, C., Sinigaglia, F., & Rogge, L. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.10.6698 · Cited by 71 · see citing works

Transcriptional Repression of the IL-2 Gene in Th Cells by ZEB

Yasui, D. H., Genetta, T., Kadesch, T. R., et al. (1998) · The Journal of Immunology · doi:10.4049/jimmunol.160.9.4433 · Cited by 64 · see citing works

T-box family reunion

Papaioannou, V. E. (1997) · Trends in Genetics · doi:10.1016/s0168-9525(97)01144-x · Cited by 42 · see citing works

Transcriptional Regulation: : Converting an activator into a repressor

Ip, Y. T. (1995) · Current Biology · doi:10.1016/s0960-9822(95)00001-7 · Cited by 37 · see citing works

IL-2 promoter-driven lacZ expression as a monitoring tool for IL-2 expression in primary T cells of transgenic mice

Brombacher, F., Schäfer, T. C., Welssensteln, U., et al. (1994) · International Immunology · doi:10.1093/intimm/6.2.189 · Cited by 36 · see citing works

Annual review of immunology, Vol. 1

Wells, J. V. (1984) · The Medical Journal of Australia · doi:10.5694/j.1326-5377.1984.tb108304.x · Cited by 10 · see citing works

The Orphan Nuclear Receptor RORγt Directs the Differentiation Program of Proinflammatory IL-17+ T Helper Cells

Ivanov, I. I., McKenzie, B. S., Zhou, L., Tadokoro, C. E., Lepelley, A., Lafaille, J. J., Cua, D. J., & Littman, D. R. (2006) · Cell · doi:10.1016/j.cell.2006.07.035 · Cited by 5,145 · see citing works

Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages

Harrington, L. E., Hatton, R. D., Mangan, P. R., Turner, H., Murphy, T. L., Murphy, K. M., & Weaver, C. T. (2005) · Nature Immunology · doi:10.1038/ni1254 · Cited by 4,742 · see citing works

Master Transcription Factors and Mediator Establish Super-Enhancers at Key Cell Identity Genes

Whyte, W. A., Orlando, D. A., Hnisz, D., Abraham, B. J., Lin, C. Y., Kagey, M. H., Rahl, P. B., Lee, T. I., & Young, R. A. (2013) · Cell · doi:10.1016/j.cell.2013.03.035 · Cited by 4,143 · see citing works

TGFβ in the Context of an Inflammatory Cytokine Milieu Supports De Novo Differentiation of IL-17-Producing T Cells

Veldhoen, M., Hocking, R. J., Atkins, C. J., Locksley, R. M., & Stockinger, B. (2006) · Immunity · doi:10.1016/j.immuni.2006.01.001 · Cited by 3,605 · see citing works

Differentiation of Effector CD4 T Cell Populations

Zhu, J., Yamane, H., & Paul, W. E. (2010) · Annual Review of Immunology · doi:10.1146/annurev-immunol-030409-101212 · Cited by 3,452 · see citing works

Central Memory and Effector Memory T Cell Subsets: Function, Generation, and Maintenance

Sallusto, F., Geginat, J., & Lanzavecchia, A. (2004) · Annual Review of Immunology · doi:10.1146/annurev.immunol.22.012703.104702 · Cited by 3,067 · see citing works

Atezolizumab versus docetaxel for patients with previously treated non-small-cell lung cancer (POPLAR): a multicentre, open-label, phase 2 randomised controlled trial

Fehrenbacher, L., Spira, A., Ballinger, M., Kowanetz, M., Vansteenkiste, J., Mazieres, J., Park, K., Smith, D., Artal-Cortes, A., Lewanski, C., et al. (2016) · The Lancet · doi:10.1016/s0140-6736(16)00587-0 · Cited by 2,756 · see citing works

Inflammation Directs Memory Precursor and Short-Lived Effector CD8+ T Cell Fates via the Graded Expression of T-bet Transcription Factor

Joshi, N. S., Cui, W., Chandele, A., Lee, H. K., Urso, D. R., Hagman, J., Gapin, L., & Kaech, S. M. (2007) · Immunity · doi:10.1016/j.immuni.2007.07.010 · Cited by 1,861 · see citing works

Th17: An Effector CD4 T Cell Lineage with Regulatory T Cell Ties

Weaver, C. T., Harrington, L. E., Mangan, P. R., Gavrieli, M., & Murphy, K. M. (2006) · Immunity · doi:10.1016/j.immuni.2006.06.002 · Cited by 1,422 · see citing works

Interleukin-17 and Type 17 Helper T Cells

Miossec, P., Korn, T., & Kuchroo, V. K. (2009) · New England Journal of Medicine · doi:10.1056/nejmra0707449 · Cited by 1,409 · see citing works

Interferon-Gamma at the Crossroads of Tumor Immune Surveillance or Evasion

Castro, F., Cardoso, A. P., Gonçalves, R. M., Serre, K., & Oliveira, M. J. (2018) · Frontiers in Immunology · doi:10.3389/fimmu.2018.00847 · Cited by 1,224 · see citing works

The transcription factor T-bet controls regulatory T cell homeostasis and function during type 1 inflammation

Koch, M. A., Tucker-Heard, G., Perdue, N. R., Killebrew, J. R., Urdahl, K. B., & Campbell, D. J. (2009) · Nature Immunology · doi:10.1038/ni.1731 · Cited by 1,258 · see citing works

Roles of IFN-γ in tumor progression and regression: A review

Jorgovanovic, D., Song, M., Wang, L., & Zhang, Y. (2020) · Biomarker Research · doi:10.1186/s40364-020-00228-x · Cited by 1,234 · see citing works

Follicular regulatory T cells expressing Foxp3 and Bcl-6 suppress germinal center reactions

Chung, Y., Tanaka, S., Chu, F., Nurieva, R. I., Martinez, G. J., Rawal, S., Wang, Y.-H., Lim, H., Reynolds, J. M., Zhou, X.-H., et al. (2011) · Nature Medicine · doi:10.1038/nm.2426 · Cited by 1,120 · see citing works

IL-4 inhibits TGF-β-induced Foxp3+ T cells and, together with TGF-β, generates IL-9+ IL-10+ Foxp3− effector T cells

Dardalhon, V., Awasthi, A., Kwon, H., Galileos, G., Gao, W., Sobel, R. A., Mitsdoerffer, M., Strom, T. B., Elyaman, W., Ho, I.-C., et al. (2008) · Nature Immunology · doi:10.1038/ni.1677 · Cited by 1,122 · see citing works

Production of interleukin 22 but not interleukin 17 by a subset of human skin-homing memory T cells

Duhen, T., Geiger, R., Jarrossay, D., Lanzavecchia, A., & Sallusto, F. (2009) · Nature Immunology · doi:10.1038/ni.1767 · Cited by 1,079 · see citing works

Control of Effector CD8 ⁺ T Cell Function by the Transcription Factor <i>Eomesodermin</i>

Pearce, E. L., Mullen, A. C., Martins, G. A., Krawczyk, C. M., Hutchins, A. S., Zediak, V. P., Banica, M., DiCioccio, C. B., Gross, D. A., Mao, C.-A., et al. (2003) · Science · doi:10.1126/science.1090148 · Cited by 1,014 · see citing works

Successful Anti-PD-1 Cancer Immunotherapy Requires T Cell-Dendritic Cell Crosstalk Involving the Cytokines IFN-γ and IL-12

Garris, C. S., Arlauckas, S. P., Kohler, R. H., Trefny, M. P., Garren, S., Piot, C., Engblom, C., Pfirschke, C., Siwicki, M., Gungabeesoon, J., et al. (2018) · Immunity · doi:10.1016/j.immuni.2018.09.024 · Cited by 966 · see citing works

The who's who of <scp>T</scp> ‐cell differentiation: Human memory <scp>T</scp> ‐cell subsets

Mahnke, Y. D., Brodie, T. M., Sallusto, F., Roederer, M., & Lugli, E. (2013) · European Journal of Immunology · doi:10.1002/eji.201343751 · Cited by 817 · see citing works

A dominant function for interleukin 27 in generating interleukin 10–producing anti-inflammatory T cells

Awasthi, A., Carrier, Y., Peron, J. P. S., Bettelli, E., Kamanaka, M., Flavell, R. A., Kuchroo, V. K., Oukka, M., & Weiner, H. L. (2007) · Nature Immunology · doi:10.1038/ni1541 · Cited by 804 · see citing works

Aerobic glycolysis promotes T helper 1 cell differentiation through an epigenetic mechanism

Peng, M., Yin, N., Chhangawala, S., Xu, K., Leslie, C. S., & Li, M. O. (2016) · Science · doi:10.1126/science.aaf6284 · Cited by 787 · see citing works

Transforming growth factor-β in T-cell biology

Gorelik, L., & Flavell, R. A. (2002) · Nature Reviews Immunology · doi:10.1038/nri704 · Cited by 792 · see citing works

T-bet is rapidly induced by interferon-γ in lymphoid and myeloid cells

Lighvani, A. A., Frucht, D. M., Jankovic, D., Yamane, H., Aliberti, J., Hissong, B. D., Nguyen, B. V., Gadina, M., Sher, A., Paul, W. E., et al. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.261570598 · Cited by 783 · see citing works

Tryptophan-derived microbial metabolites activate the aryl hydrocarbon receptor in tumor-associated macrophages to suppress anti-tumor immunity

Hezaveh, K., Shinde, R. S., Klötgen, A., Halaby, M. J., Lamorte, S., Ciudad, M. T., Quevedo, R., Neufeld, L., Liu, Z. Q., Jin, R., et al. (2022) · Immunity · doi:10.1016/j.immuni.2022.01.006 · Cited by 746 · see citing works

The role of T helper 17 (Th17) and regulatory T cells (Treg) in human organ transplantation and autoimmune disease

Afzali, B., Lombardi, G., Lechler, R. I., & Lord, G. M. (2007) · Clinical and Experimental Immunology · doi:10.1111/j.1365-2249.2007.03356.x · Cited by 762 · see citing works

The mTOR Kinase Determines Effector versus Memory CD8+ T Cell Fate by Regulating the Expression of Transcription Factors T-bet and Eomesodermin

Rao, R. R., Li, Q., Odunsi, K., & Shrikant, P. A. (2010) · Immunity · doi:10.1016/j.immuni.2009.10.010 · Cited by 656 · see citing works

Mepolizumab, a humanized anti–IL-5 mAb, as a treatment option for severe nasal polyposis

Gevaert, P., Van Bruaene, N., Cattaert, T., Van Steen, K., Van Zele, T., Acke, F., De Ruyck, N., Blomme, K., Sousa, A. R., Marshall, R. P., et al. (2011) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2011.07.056 · Cited by 629 · see citing works

Microbial lipopeptides induce the production of IL-17 in Th cells

Infante-Duarte, C., Horton, H. F., Byrne, M. C., & Kamradt, T. (2000) · The Journal of Immunology · doi:10.4049/jimmunol.165.11.6107 · Cited by 586 · see citing works

CTLA-4 blockade increases IFNγ-producing CD4 ⁺ ICOS ^hi cells to shift the ratio of effector to regulatory T cells in cancer patients

Liakou, C. I., Kamat, A., Tang, D. N., Chen, H., Sun, J., Troncoso, P., Logothetis, C., & Sharma, P. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0806075105 · Cited by 549 · see citing works

Guidelines for the use of flow cytometry and cell sorting in immunological studies (third edition)

Cossarizza, A., Chang, H., Radbruch, A., Abrignani, S., Addo, R., Akdis, M., Andrä, I., Andreata, F., Annunziato, F., Arranz, E., et al. (2021) · European Journal of Immunology · doi:10.1002/eji.202170126 · Cited by 531 · see citing works

T Helper Cell Fate Specified by Kinase-Mediated Interaction of T-bet with GATA-3

Hwang, E. S., Szabo, S. J., Schwartzberg, P. L., & Glimcher, L. H. (2005) · Science · doi:10.1126/science.1103336 · Cited by 519 · see citing works

A critical role for NF-κB in Gata3 expression and TH2 differentiation in allergic airway inflammation

Das, J., Chen, C.-H., Yang, L., Cohn, L., Ray, P., & Ray, A. (2001) · Nature Immunology · doi:10.1038/83158 · Cited by 518 · see citing works

Helper T cell differentiation

Saravia, J., Chapman, N. M., & Chi, H. (2019) · Cellular &amp; Molecular Immunology · doi:10.1038/s41423-019-0220-6 · Cited by 489 · see citing works

Progressive differentiation and selection of the fittest in the immune response

Lanzavecchia, A., & Sallusto, F. (2002) · Nature Reviews Immunology · doi:10.1038/nri959 · Cited by 495 · see citing works

T-bet: a bridge between innate and adaptive immunity

Lazarevic, V., Glimcher, L. H., & Lord, G. M. (2013) · Nature Reviews Immunology · doi:10.1038/nri3536 · Cited by 486 · see citing works

Age-Associated B Cells

Cancro, M. P. (2020) · Annual Review of Immunology · doi:10.1146/annurev-immunol-092419-031130 · Cited by 464 · see citing works

T cell responses: naïve to memory and everything in between

Pennock, N. D., White, J. T., Cross, E. W., Cheney, E. E., Tamburini, B. A., & Kedl, R. M. (2013) · Advances in Physiology Education · doi:10.1152/advan.00066.2013 · Cited by 461 · see citing works

An Essential Role of the Transcription Factor GATA-3 for the Function of Regulatory T Cells

Wang, Y., Su, M. A., & Wan, Y. Y. (2011) · Immunity · doi:10.1016/j.immuni.2011.08.012 · Cited by 461 · see citing works

The IL-23-IL-17 axis in inflammatory arthritis

Lubberts, E. (2015) · Nature Reviews Rheumatology · doi:10.1038/nrrheum.2015.53 · Cited by 442 · see citing works

Disruption of tumour-associated macrophage trafficking by the osteopontin-induced colony-stimulating factor-1 signalling sensitises hepatocellular carcinoma to anti-PD-L1 blockade

Zhu, Y., Yang, J., Xu, D., Gao, X.-M., Zhang, Z., Hsu, J. L., Li, C.-W., Lim, S.-O., Sheng, Y.-Y., Zhang, Y., et al. (2019) · Gut · doi:10.1136/gutjnl-2019-318419 · Cited by 419 · see citing works

<scp>mTOR</scp> , metabolism, and the regulation of T‐cell differentiation and function

Waickman, A. T., & Powell, J. D. (2012) · Immunological Reviews · doi:10.1111/j.1600-065x.2012.01152.x · Cited by 420 · see citing works

Semaphorins and their receptors in immune cell interactions

Suzuki, K., Kumanogoh, A., & Kikutani, H. (2008) · Nature Immunology · doi:10.1038/ni1553 · Cited by 400 · see citing works

Direct regulation of Gata3 expression determines the T helper differentiation potential of Notch

Amsen, D., Antov, A., Jankovic, D., Sher, A., Radtke, F., Souabni, A., Busslinger, M., McCright, B., Gridley, T., & Flavell, R. A. (2007) · Immunity · doi:10.1016/j.immuni.2007.05.021 · Cited by 396 · see citing works

Aging, obesity, and inflammatory age-related diseases

Frasca, D., Blomberg, B. B., & Paganelli, R. (2017) · Frontiers in Immunology · doi:10.3389/fimmu.2017.01745 · Cited by 371 · see citing works

Iron in infection and immunity

Nairz, M., & Weiss, G. (2020) · Molecular Aspects of Medicine · doi:10.1016/j.mam.2020.100864 · Cited by 359 · see citing works

Glucose Availability Regulates IFN-γ Production and p70S6 Kinase Activation in CD8+ Effector T Cells

Cham, C. M., & Gajewski, T. F. (2005) · The Journal of Immunology · doi:10.4049/jimmunol.174.8.4670 · Cited by 359 · see citing works

Heterogeneity of CD4⁺ memory T cells: Functional modules for tailored immunity

Sallusto, F., & Lanzavecchia, A. (2009) · European Journal of Immunology · doi:10.1002/eji.200939722 · Cited by 348 · see citing works

Acetate Promotes T Cell Effector Function during Glucose Restriction

Qiu, J., Villa, M., Sanin, D. E., Buck, M. D., O’Sullivan, D., Ching, R., Matsushita, M., Grzes, K. M., Winkler, F., Chang, C.-H., et al. (2019) · Cell Reports · doi:10.1016/j.celrep.2019.04.022 · Cited by 342 · see citing works

T-bet and GATA3 orchestrate Th1 and Th2 differentiation through lineage-specific targeting of distal regulatory elements

Kanhere, A., Hertweck, A., Bhatia, U., Gökmen, M. R., Perucha, E., Jackson, I., Lord, G. M., & Jenner, R. G. (2012) · Nature Communications · doi:10.1038/ncomms2260 · Cited by 345 · see citing works

Stat3 and Gfi-1 transcription factors control Th17 cell immunosuppressive activity via the regulation of ectonucleotidase expression

Chalmin, F., Mignot, G., Bruchard, M., Chevriaux, A., Végran, F., Hichami, A., Ladoire, S., Derangère, V., Vincent, J., Masson, D., et al. (2012) · Immunity · doi:10.1016/j.immuni.2011.12.019 · Cited by 338 · see citing works

The Transcription Factor T-bet Is Induced by Multiple Pathways and Prevents an Endogenous Th2 Cell Program during Th1 Cell Responses

Zhu, J., Jankovic, D., Oler, A. J., Wei, G., Sharma, S., Hu, G., Guo, L., Yagi, R., Yamane, H., Punkosdy, G., et al. (2012) · Immunity · doi:10.1016/j.immuni.2012.09.007 · Cited by 335 · see citing works

Single-cell transcriptomics identifies an effectorness gradient shaping the response of CD4+ T cells to cytokines

Cano-Gamez, K., Soskic, B., Roumeliotis, T. I., So, E., Smyth, D. J., Baldrighi, M., Willé, D., Nakic, N., Esparza-Gordillo, J., Larminie, C. G. C., et al. (2020) · Nature Communications · doi:10.1038/s41467-020-15543-y · Cited by 274 · see citing works

Persistence of naive CD45RA+ regulatory T cells in adult life

Seddiki, N., Santner-Nanan, B., Tangye, S. G., Alexander, S. I., Solomon, M., Lee, S., Nanan, R., & de Saint Groth, B. F. (2006) · Blood · doi:10.1182/blood-2005-06-2403 · Cited by 284 · see citing works

T-bet is required for optimal proinflammatory CD4+ T-cell trafficking

Lord, G. M. (2005) · Blood · doi:10.1182/blood-2005-04-1393 · Cited by 270 · see citing works

Microbiota metabolite butyrate differentially regulates Th1 and Th17 cells' differentiation and function in induction of colitis

Chen, L., Sun, M., Wu, W., Yang, W., Huang, X., Xiao, Y., Ma, C., Xu, L., Yao, S., Liu, Z., et al. (2019) · Inflammatory Bowel Diseases · doi:10.1093/ibd/izz046 · Cited by 231 · see citing works

Anti-CTLA-4 therapy results in higher CD4 ⁺ ICOS ^hi T cell frequency and IFN-γ levels in both nonmalignant and malignant prostate tissues

Chen, H., Liakou, C. I., Kamat, A., Pettaway, C., Ward, J. F., Tang, D. N., Sun, J., Jungbluth, A. A., Troncoso, P., Logothetis, C., et al. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0813175106 · Cited by 218 · see citing works

Helios+ and Helios− Cells Coexist within the Natural FOXP3+ T Regulatory Cell Subset in Humans

Himmel, M. E., MacDonald, K. G., Garcia, R. V., Steiner, T. S., & Levings, M. K. (2013) · The Journal of Immunology · doi:10.4049/jimmunol.1201379 · Cited by 217 · see citing works

Molecular profiling of cytomegalovirus-induced human CD8+ T cell differentiation

Hertoghs, K. M. L., Moerland, P. D., van Stijn, A., Remmerswaal, E. B. M., Yong, S. L., van de Berg, P. J. E. J., van Ham, S. M., Baas, F., ten Berge, I. J. M., & van Lier, R. A. W. (2010) · Journal of Clinical Investigation · doi:10.1172/jci42758 · Cited by 198 · see citing works

STAT5 programs a distinct subset of GM-CSF-producing T helper cells that is essential for autoimmune neuroinflammation

Sheng, W., Yang, F., Zhou, Y., Yang, H., Low, P. Y., Kemeny, D. M., Tan, P., Moh, A., Kaplan, M. H., Zhang, Y., et al. (2014) · Cell Research · doi:10.1038/cr.2014.154 · Cited by 203 · see citing works

T-helper cell type-2 regulation in allergic disease

Georas, S. N., Guo, J., De Fanis, U., & Casolaro, V. (2005) · European Respiratory Journal · doi:10.1183/09031936.05.00006005 · Cited by 181 · see citing works

Human memory T cells with a naive phenotype accumulate with aging and respond to persistent viruses

Pulko, V., Davies, J. S., Martinez, C., Lanteri, M. C., Busch, M. P., Diamond, M. S., Knox, K., Bush, E. C., Sims, P. A., Sinari, S., et al. (2016) · Nature Immunology · doi:10.1038/ni.3483 · Cited by 175 · see citing works

Dynamic balance between master transcription factors determines the fates and functions of CD4 T cell and innate lymphoid cell subsets

Fang, D., & Zhu, J. (2017) · Journal of Experimental Medicine · doi:10.1084/jem.20170494 · Cited by 175 · see citing works

Repositioning TH cell polarization from single cytokines to complex help

Tuzlak, S., Dejean, A. S., Iannacone, M., Quintana, F. J., Waisman, A., Ginhoux, F., Korn, T., & Becher, B. (2021) · Nature Immunology · doi:10.1038/s41590-021-01009-w · Cited by 171 · see citing works

Dysregulation of Th1, Th2, Th17, and T regulatory cell-related transcription factor signaling in children with autism

Ahmad, S. F., Zoheir, K. M. A., Ansari, M. A., Nadeem, A., Bakheet, S. A., AL-Ayadhi, L. Y., Alzahrani, M. Z., Al-Shabanah, O. A., Al-Harbi, M. M., & Attia, S. M. (2017) · Molecular Neurobiology · doi:10.1007/s12035-016-9977-0 · Cited by 155 · see citing works

Mucosal-associated invariant T cells promote inflammation and intestinal dysbiosis leading to metabolic dysfunction during obesity

Toubal, A., Kiaf, B., Beaudoin, L., Cagninacci, L., Rhimi, M., Fruchet, B., da Silva, J., Corbett, A. J., Simoni, Y., Lantz, O., et al. (2020) · Nature Communications · doi:10.1038/s41467-020-17307-0 · Cited by 165 · see citing works

Nitric oxide induces CD4 ⁺ CD25 ⁺ Foxp3 ⁻ regulatory T cells from CD4 ⁺ CD25 ⁻ T cells via p53, IL-2, and OX40

Niedbala, W., Cai, B., Liu, H., Pitman, N., Chang, L., & Liew, F. Y. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0703725104 · Cited by 156 · see citing works

STAT3, a master regulator of anti-tumor immune response

Rébé, C., & Ghiringhelli, F. (2019) · Cancers · doi:10.3390/cancers11091280 · Cited by 129 · see citing works

Mechanisms underlying immune effects of dietary oligosaccharides

Jeurink, P. V., van Esch, B. C., Rijnierse, A., Garssen, J., & Knippels, L. M. (2013) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.112.038596 · Cited by 129 · see citing works

Human Th1 and Th17 Cells Exhibit Epigenetic Stability at Signature Cytokine and Transcription Factor Loci

Cohen, C. J., Crome, S. Q., MacDonald, K. G., Dai, E. L., Mager, D. L., & Levings, M. K. (2011) · The Journal of Immunology · doi:10.4049/jimmunol.1101058 · Cited by 112 · see citing works

Genetic Reprogramming of Primary Human T Cells Reveals Functional Plasticity in Th Cell Differentiation

Sundrud, M. S., Grill, S. M., Ni, D., Nagata, K., Alkan, S. S., Subramaniam, A., & Unutmaz, D. (2003) · The Journal of Immunology · doi:10.4049/jimmunol.171.7.3542 · Cited by 112 · see citing works

NAD+ protects against EAE by regulating CD4+ T-cell differentiation

Tullius, S. G., Biefer, H. R. C., Li, S., Trachtenberg, A. J., Edtinger, K., Quante, M., Krenzien, F., Uehara, H., Yang, X., Kissick, H. T., et al. (2014) · Nature Communications · doi:10.1038/ncomms6101 · Cited by 107 · see citing works

Characterizing cellular heterogeneity in chromatin state with scCUT&amp;Tag-pro

Zhang, B., Srivastava, A., Mimitou, E., Stuart, T., Raimondi, I., Hao, Y., Smibert, P., & Satija, R. (2022) · Nature Biotechnology · doi:10.1038/s41587-022-01250-0 · Cited by 104 · see citing works

Blockade of IL-23: What is in the Pipeline?

Parigi, T. L., Iacucci, M., & Ghosh, S. (2022) · Journal of Crohn's and Colitis · doi:10.1093/ecco-jcc/jjab185 · Cited by 93 · see citing works

Partial Sleep Restriction Activates Immune Response-Related Gene Expression Pathways: Experimental and Epidemiological Studies in Humans

Aho, V., Ollila, H. M., Rantanen, V., Kronholm, E., Surakka, I., van Leeuwen, W. M. A., Lehto, M., Matikainen, S., Ripatti, S., Härmä, M., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0077184 · Cited by 93 · see citing works

Airway Epithelial Cells Regulate the Functional Phenotype of Locally Differentiating Dendritic Cells: Implications for the Pathogenesis of Infectious and Allergic Airway Disease

Rate, A., Upham, J. W., Bosco, A., McKenna, K. L., & Holt, P. G. (2009) · The Journal of Immunology · doi:10.4049/jimmunol.182.1.72 · Cited by 88 · see citing works

Molecular profiling of BRAF-V600E-mutant metastatic colorectal cancer in the phase 3 BEACON CRC trial

Kopetz, S., Murphy, D. A., Pu, J., Ciardiello, F., Desai, J., Van Cutsem, E., Wasan, H. S., Yoshino, T., Saffari, H., Zhang, X., et al. (2024) · Nature Medicine · doi:10.1038/s41591-024-03235-9 · Cited by 82 · see citing works

T cells lacking HDAC11 have increased effector functions and mediate enhanced alloreactivity in a murine model

Woods, D. M., Woan, K. V., Cheng, F., Sodré, A. L., Wang, D., Wu, Y., Wang, Z., Chen, J., Powers, J., Pinilla-Ibarz, J., et al. (2017) · Blood · doi:10.1182/blood-2016-08-731505 · Cited by 74 · see citing works

Increased bleomycin-induced lung injury in mice deficient in the transcription factor T-bet

Xu, J., Mora, A. L., LaVoy, J., Brigham, K. L., & Rojas, M. (2006) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.00006.2006 · Cited by 63 · see citing works

Dysregulation of the Th1/Th2 cytokine profile is associated with immunosuppression induced by hypothalamic-pituitary-adrenal axis activation in mice

Viveros-Paredes, J. M., Puebla-Pérez, A. M., Gutiérrez-Coronado, O., Sandoval-Ramírez, L., & Villaseñor-García, M. M. (2006) · International Immunopharmacology · doi:10.1016/j.intimp.2005.11.011 · Cited by 62 · see citing works

Overexpression of the transcription factor GATA-3 enhances the development of pulmonary fibrosis

Kimura, T., Ishii, Y., Yoh, K., Morishima, Y., Iizuka, T., Kiwamoto, T., Matsuno, Y., Homma, S., Nomura, A., Sakamoto, T., et al. (2006) · The American Journal of Pathology · doi:10.2353/ajpath.2006.051160 · Cited by 55 · see citing works

Autoimmune diseases: Role of steroid hormones

Benagiano, M., Bianchi, P., D'Elios, M. M., Brosens, I., & Benagiano, G. (2019) · Best Practice &amp; Research Clinical Obstetrics &amp; Gynaecology · doi:10.1016/j.bpobgyn.2019.03.001 · Cited by 49 · see citing works

Rapid Recall Ability of Memory T cells is Encoded in their Epigenome

Barski, A., Cuddapah, S., Kartashov, A. V., Liu, C., Imamichi, H., Yang, W., Peng, W., Lane, H. C., & Zhao, K. (2017) · Scientific Reports · doi:10.1038/srep39785 · Cited by 49 · see citing works

Cancer-specific tissue-resident memory T-cells express ZNF683 in colorectal cancer

Kitakaze, M., Uemura, M., Hara, T., Chijimatsu, R., Motooka, D., Hirai, T., Konno, M., Okuzaki, D., Sekido, Y., Hata, T., et al. (2023) · British Journal of Cancer · doi:10.1038/s41416-023-02202-4 · Cited by 49 · see citing works

Effects of environmental tobacco smoke exposure on pulmonary immune response in infant monkeys

Wang, L., Joad, J. P., Zhong, C., & Pinkerton, K. E. (2008) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2008.04.011 · Cited by 48 · see citing works

Development of Allergen-Induced Airway Inflammation in the Absence of T-bet Regulation Is Dependent on IL-17

Durrant, D. M., Gaffen, S. L., Riesenfeld, E. P., Irvin, C. G., & Metzger, D. W. (2009) · The Journal of Immunology · doi:10.4049/jimmunol.0803109 · Cited by 48 · see citing works

Male sex chromosomal complement exacerbates the pathogenicity of Th17 cells in a chronic model of central nervous system autoimmunity

Doss, P. M. I. A., Umair, M., Baillargeon, J., Fazazi, R., Fudge, N., Akbar, I., Yeola, A. P., Williams, J. B., Leclercq, M., Joly-Beauparlant, C., et al. (2021) · Cell Reports · doi:10.1016/j.celrep.2021.108833 · Cited by 39 · see citing works

Regulatory-T, T-Helper 1, and T-Helper 2 Cell Differentiation in Nasal Mucosa of Allergic Rhinitis with Olive Pollen Sensitivity

Sogut, A., Yilmaz, O., Kirmaz, C., Ozbilgin, K., Onur, E., Celik, O., Pinar, E., Vatansever, S., Dinc, G., & Yuksel, H. (2012) · International Archives of Allergy and Immunology · doi:10.1159/000329159 · Cited by 33 · see citing works

The immune cell transcription factor T-bet: A novel metabolic regulator

Stolarczyk, E., Lord, G. M., & Howard, J. K. (2014) · Adipocyte · doi:10.4161/adip.26220 · Cited by 32 · see citing works

Picroside II Attenuates Airway Inflammation by Downregulating the Transcription Factor GATA3 and Th2-Related Cytokines in a Mouse Model of HDM-Induced Allergic Asthma

Choi, J., Choi, B. K., Kim, J. S., Lee, J.-W., Park, H. A., Ryu, H. W., Lee, S. U., Hwang, K. W., Yun, W.-K., Kim, H.-C., et al. (2016) · PLOS ONE · doi:10.1371/journal.pone.0167098 · Cited by 30 · see citing works

Differential gene expression following TLR stimulation in rag1-/- mutant zebrafish tissues and morphological descriptions of lymphocyte-like cell populations

Muire, P. J., Hanson, L. A., Wills, R., & Petrie-Hanson, L. (2017) · PLOS ONE · doi:10.1371/journal.pone.0184077 · Cited by 21 · see citing works

FURIN regulates cytotoxic T-lymphocyte effector function and memory cell transition in mice

Ojanen, M. J. T., Caro, F. M., Aittomäki, S., Ploquin, M. J., Ortutay, Z., Pekkarinen, M., Kesseli, J., Vähätupa, M., Määttä, J., Nykter, M., et al. (2023) · European Journal of Immunology · doi:10.1002/eji.202250246 · Cited by 10 · see citing works

Prevention and inhibition of adverse humoral immune response to gene therapy mediated by adeno-associated virus (AAV) vector

Meliani, A. (2026) · doi:10.70675/83ee599czfe90z44e6za201z0938409e1748

Molecular Basis of Transient Repression of β-Galactosidase in Escherichia coli

Tyler, B., & Magasanik, B. (1969) · Journal of Bacteriology · doi:10.1128/jb.97.2.550-556.1969 · Cited by 34 · see citing works

Two Systems of Glucose Repression of the GAL1 Promoter in Saccharomyces cerevisiae

Flick, J. S., & Johnston, M. (1990) · Molecular and Cellular Biology · doi:10.1128/mcb.10.9.4757-4769.1990 · Cited by 53 · see citing works

Two systems of glucose repression of the GAL1 promoter in Saccharomyces cerevisiae.

Flick, J. S., & Johnston, M. (1990) · Molecular and Cellular Biology · doi:10.1128/mcb.10.9.4757 · Cited by 179 · see citing works

Su(z)2 Antagonizes Auto-Repression of Myc in Drosophila, Increasing Myc Levels and Subsequent Trans-Activation

Khan, A. A., Shover, W., & Goodliffe, J. M. (2009) · PLoS ONE · doi:10.1371/journal.pone.0005076 · Cited by 12 · see citing works

EIN3 and RSL4 interfere with an MYB–bHLH–WD40 complex to mediate ethylene-induced ectopic root hair formation in Arabidopsis

Qiu, Y., Tao, R., Feng, Y., et al. (2021) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2110004118 · Cited by 57 · see citing works