Transcriptional regulation of Th1/Th2 polarization
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Exposure to allergens causes differentiation of CD4+ T cells into effector T cells, Th1, Th2 and Th17 cells, which produce lineage-specific cytokines IFNγ, IL-4 and IL-17, respectively.
“Exposure to allergens causes differentiation of CD4+ T cells into effector T cells, Th1, Th2 and Th17 cells, which produce lineage-specific cytokines IFNγ, IL-4 and IL-17, respectively [9, 10].”
Cites
Zheng, W.-P., & Flavell, R. A. (1997) · Cell · doi:10.1016/s0092-8674(00)80240-8 · Cited by 2,384 · see citing works
Lee, H. J., Takemoto, N., Kurata, H., Kamogawa, Y., Miyatake, S., O'Garra, A., & Arai, N. (2000) · The Journal of Experimental Medicine · doi:10.1084/jem.192.1.105 · Cited by 393 · see citing works
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Phenotypic and functional features of human Th17 cells
Annunziato, F., Cosmi, L., Santarlasci, V., Maggi, L., Liotta, F., Mazzinghi, B., Parente, E., Filì, L., Ferri, S., Frosali, F., et al. (2007) · The Journal of Experimental Medicine · doi:10.1084/jem.20070663 · Cited by 1,861 · see citing works
Modulation of adipokines and cytokines in gestational diabetes and macrosomia
Atègbo, J.-M., Grissa, O., Yessoufou, A., Hichami, A., Dramane, K. L., Moutairou, K., Miled, A., Grissa, A., Jerbi, M., Tabka, Z., et al. (2006) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2006-0980 · Cited by 398 · see citing works
Signaling pathways in Th2 development
Mowen, K. A., & Glimcher, L. H. (2004) · Immunological Reviews · doi:10.1111/j.0105-2896.2004.00209.x · Cited by 255 · see citing works
Self-citationSundrud, M. S., Grill, S. M., Ni, D., Nagata, K., Alkan, S. S., Subramaniam, A., & Unutmaz, D. (2003) · The Journal of Immunology · doi:10.4049/jimmunol.171.7.3542 · Cited by 112 · see citing works
Choi, J., Choi, B. K., Kim, J. S., Lee, J.-W., Park, H. A., Ryu, H. W., Lee, S. U., Hwang, K. W., Yun, W.-K., Kim, H.-C., et al. (2016) · PLOS ONE · doi:10.1371/journal.pone.0167098 · Cited by 30 · see citing works
Zhang, Q.-Q., Zhang, W.-J., & Chang, S. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1168848 · Cited by 24 · see citing works
- Authors
- Rengarajan, J., Szabo, S. J., & Glimcher, L. H.
- Affiliations
- Harvard University (US)
- Corresponding author
- Glimcher, Laurie H
- Venue
- Immunology Today
- Publisher
- Elsevier BV
- Published
- 2000-10
- Volume
- 21
- Issue
- 10
- Pages
- 479-483
- ISSN
- 0167-5699 (ISSN-L)
- OpenAlex
- W1980110512
- Cited by
- 433
- References
- 2
- Citations by year
- 2025: 4 · 2024: 6 · 2023: 3 · 2022: 9 · 2021: 9 · 2020: 17 · 2019: 8 · 2018: 17 · 2017: 19 · 2016: 13 · 2015: 19 · 2014: 12 · 2013: 17 · 2012: 13
- FWCI
- 2.27
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Immunology Today (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institute of Allergy and Infectious Diseases (R01AI048126, AI-31541, AI43953, R01AI043953, AI48126)
- Topics
- Life Sciences › Immunology and Microbiology › Immunology › T-cell and B-cell Immunology
- Life Sciences › Immunology and Microbiology › Immunology › Psoriasis: Treatment and Pathogenesis
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Genomics and Chromatin Dynamics
- Keywords
- Th1/Th2 polarization, T helper cell differentiation, transcriptional regulation, interferon-gamma, IL-4, cytokine gene expression, transcription factors, chromatin remodeling
- MeSH terms
- Cell Differentiation, Chromatin, DNA-Binding Proteins, Humans, Interferon-gamma, Proto-Oncogene Proteins, Transcription Factors, Transcription, Genetic, Trans-Activators, Interleukin-4, Th1 Cells, Th2 Cells, GATA3 Transcription Factor, Proto-Oncogene Proteins c-maf
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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