The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Quorum sensing-controlled gene expression in lactic acid bacteria
Open accessAbstract
Quorum sensing in lactic acid bacteria (LAB) involves peptides that are directly sensed by membrane-located histidine kinases, after which the signal is transmitted to an intracellular response regulator. This regulator in turn activates transcription of target genes, that commonly include the structural gene for the inducer molecule. The two-component signal-transduction machinery has proven to be indispensable for transcription activation and production of several autoinducers found in LAB, which are predominantly bacteriocins or bacteriocin-like peptides. In the nisin autoregulation process in Lactococcus lactis the NisK protein acts as the sensor for nisin and the NisR protein as the response regulator, activating transcription of target genes. The cis-acting elements for NisR were identified as the nisA and nisF promoter fragments and these were further analysed for inducibility. Based on this knowledge efficient nisin-controlled expression (NICE) systems were developed for several different lactic acid bacteria. A promising application of the NICE system is the development of autolytic starter lactococci, which will lyse in an early stage during cheese ripening thereby facilitating the release of intracellular enzymes which can contribute to flavour formation.
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Cites
van der Meer, J. R., Polman, J., Beerthuyzen, M. M., Siezen, R. J., Kuipers, O. P., & De Vos, W. M. (1993) · Journal of Bacteriology · doi:10.1128/jb.175.9.2578-2588.1993 · Cited by 318
Self-citation
Cited by
Bacteriocins and their food applications
And, H. C., & Hoover, D. G. (2003) · Comprehensive Reviews in Food Science and Food Safety · doi:10.1111/j.1541-4337.2003.tb00016.x · Cited by 550
A review on Lactococcus lactis: from food to factory
Song, A. A.-L., In, L. L. A., Lim, S. H. E., & Rahim, R. A. (2017) · Microbial Cell Factories · doi:10.1186/s12934-017-0669-x · Cited by 414
Bovine Rotavirus Nonstructural Protein 4 Produced by Lactococcus lactis Is Antigenic and Immunogenic
Enouf, V., Langella, P., Commissaire, J., Cohen, J., & Corthier, G. (2001) · Applied and Environmental Microbiology · doi:10.1128/aem.67.4.1423-1428.2001 · Cited by 104
Clarke, S. R., Andre, G., Walsh, E. J., Dufrêne, Y. F., Foster, T. J., & Foster, S. J. (2009) · Infection and Immunity · doi:10.1128/iai.01304-08 · Cited by 105
Immunogenicity of a malaria parasite antigen displayed by Lactococcus lactis in oral immunisations
Ramasamy, R., Yasawardena, S., Zomer, A., Venema, G., Kok, J., & Leenhouts, K. (2006) · Vaccine · doi:10.1016/j.vaccine.2006.02.040 · Cited by 102
Metadata
- Authors
- Kuipers, O. P., de Ruyter, P. G. G. A., Kleerebezem, M., & de Vos, W. M.
- Venue
- Journal of Biotechnology
- Publisher
- Elsevier BV
- Published
- 1998-09
- Volume
- 64
- Issue
- 1
- Pages
- 15-21
- ISSN
- 0168-1656 (ISSN-L)
- OpenAlex
- W2003898032
- Cited by
- 682
- References
- 1
- FWCI
- 5.12
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Kuipers, O. P., de Ruyter, P. G. G. A., Kleerebezem, M., & de Vos, W. M. (1998). Quorum sensing-controlled gene expression in lactic acid bacteria. Journal of Biotechnology. https://doi.org/10.1016/s0168-1656(98)00100-x
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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