The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Human housekeeping genes are compact
Abstract
Abstract We identify a set of 575 human genes that are expressed in all conditions tested in a publicly available database of microarray results. Based on this common occurrence, the set is expected to be rich in ‘housekeeping' genes, showing constitutive expression in all tissues. We compare selected aspects of their genomic structure with a set of background genes. We find that the introns, untranslated regions and coding sequences of the housekeeping genes are shorter, indicating a selection for compactness in these genes.
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Ucker, D. S., & Yamamoto, K. R. (1984) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)42806-7 · Cited by 190
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Robinson, M. D., & Oshlack, A. (2010) · Genome Biology · doi:10.1186/gb-2010-11-3-r25 · Cited by 7,876
The Widespread Impact of Mammalian MicroRNAs on mRNA Repression and Evolution
Farh, K. K.-H., Grimson, A., Jan, C., Lewis, B. P., Johnston, W. K., Lim, L. P., Burge, C. B., & Bartel, D. P. (2005) · Science · doi:10.1126/science.1121158 · Cited by 1,484
Yanai, I., Benjamin, H., Shmoish, M., Chalifa-Caspi, V., Shklar, M., Ophir, R., Bar-Even, A., Horn-Saban, S., Safran, M., Domany, E., et al. (2005) · Bioinformatics · doi:10.1093/bioinformatics/bti042 · Cited by 1,300
Li, G., Ruan, X., Auerbach, R. K., Sandhu, K. S., Zheng, M., Wang, P., Poh, H. M., Goh, Y., Lim, J., Zhang, J., et al. (2012) · Cell · doi:10.1016/j.cell.2011.12.014 · Cited by 1,232
Characterization of the single-cell transcriptional landscape by highly multiplex RNA-seq
Islam, S., Kjällquist, U., Moliner, A., Zajac, P., Fan, J.-B., Lönnerberg, P., & Linnarsson, S. (2011) · Genome Research · doi:10.1101/gr.110882.110 · Cited by 949
Metadata
- Authors
- Eisenberg, E., & Levanon, E. Y.
- Venue
- Trends in Genetics
- Publisher
- Elsevier BV
- Published
- 2003-07
- Volume
- 19
- Issue
- 7
- Pages
- 362-365
- ISSN
- 0168-9525 (ISSN-L)
- OpenAlex
- W2008083733
- Cited by
- 698
- References
- 1
- FWCI
- 1.59
- Type
- journal article
- Language
- en
- Open access
- closed
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- Eisenberg, E., & Levanon, E. Y. (2003). Human housekeeping genes are compact. Trends in Genetics. https://doi.org/10.1016/s0168-9525(03)00140-9
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.