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Cited by 399biodegradable polymer synthesis and propertiesAdvanced Drug Delivery SystemsHydrogels: synthesis, properties, applications

The DOI matches its Crossref record; 100 of the 108 references it cites were found in a registry or an index.

Polyanhydrides: an overview

Kumar, Neeraj, Langer, Robert S, Domb, Abraham J·2002·Advanced Drug Delivery Reviews
DOI 10.1016/s0169-409x(02)00050-9
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Abstract

Polyanhydrides have been considered to be useful biomaterials as carriers of drugs to various organs of the human body such as brain, bone, blood vessels, and eyes. They can be prepared easily from available, low cost resources and can be manipulated to meet desirable characteristics. Polyanhydrides are biocompatible and degrade in vivo into non-toxic diacid counterparts that are eliminated from the body as metabolites. Owing to their usefulness, this review focuses on the development, synthesis methods, structures and characterization of polyanhydrides, which will provide an overview for the researchers in the field. Their in vitro and in vivo degradability, toxicity, biocompatibility and applications are discussed in the subsequent chapters of this special issue on polyanhydrides and poly(ortho esters).

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Citations

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Show all 108 references

Research works printed but not linked: 14

  1. Chasin, 1988, Polyanhydrides for controlled drug delivery, Biopharm. Manuf., 1, 33
  2. Mader, 1995, Characterization of microstructures in drug delivery systems by EPR spectroscopy, Proc. Int. Symp. Controlled Release Bioact. Mater., 22, 780
  3. Yoda, 1963, Synthesis of poly(anhydrides). Crystalline and high melting poly(amide) poly(anhydrides) of methylene bis(p-carboxyphenyl) amide, J. Polym. Sci., Part A, 1, 1323
  4. Chasin, 1990, Polyanhydrides as drug delivery systems, Drugs Pharm. Sci., 45, 43
  5. Linhardt, 1983, Bioerodable polyanhydrides for controlled drug delivery, Polym. Prepr., 24, 47
  6. A.J. Domb, O. Elmalak, V.R. Shastri, Z. Ta-Shma, D.M. Masters, I. Ringel, D. Teomim, R. Langer, Polyanhydrides, in: A.J. Domb, J. Kost, D.M. Wiseman (Eds.), Handbook of Biodegradable Polymers, Harwood, London, 1997, pp. 135–159.
  7. Leong, 1984, Bioerodible polyanhydrides as a drug carrier matrix, Polym. Prepr., 25, 201
  8. A.J. Domb, S. Amselem, R. Langer, M. Maniar, Polyanhydrides as carriers of drugs, in: S. Shalaby (Ed.), Designed to Degrade Biomedical Polymers, Hanser, Munich, 1994, pp. 69–96.
  9. Davies, 1991, The analysis of the surface chemical-structure of biomedical aliphatic polyanhydrides using XPS and TOF-SIMS, J. Appl. Polym. Sci., 42, 1597, 10.1002/app.1991.070420613 · DOI
  10. Shakesheff, 1995, The study of the surface degradation of polymer blends using SIMS, XPS, SPR and AFM, Polym. Prepr., 36, 71
  11. A.G. Shard, K.M. Shakesheff, C.J. Roberts, S.J.B. Tendler, M.C. Davies, Surface characterization of bioerodible polymers using XPS, SIMS, and AFM, in: A.J. Domb, J. Kost, D.M. Wiseman (Eds.), Handbook of Biodegradable Polymers, Harwood, London, 1997, pp. 135–159.
  12. A.J. Domb, S. Amselem, Antibiotic delivery systems for the treatment of chronic bone infections, in: A.J. Domb (Ed.), Polymeric Site-Specific Pharmacotherapy, Wiley & Sons, Chichester, 1994, pp. 243–265.
  13. Carraher, 1984, Synthesis and structural characterization of phosphorus-containing aliphatic polyanhydrides, Polym. Prepr., 25, 31
  14. V.R. Shastri, P.P. Hildgen, R. Langer, Y. Najajrah, I. Ringel, A.J. Domb, Other polyesters, in: A.J. Domb, J. Kost, D.M. Wiseman (Eds.), Handbook of Biodebradable Polymers, Harwood, London, 1997, pp. 135–159.

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Metadata

Authors
Kumar, N., Langer, R. S., & Domb, A. J.
Affiliations
Hebrew University of Jerusalem (IL)
Corresponding author
Domb, Abraham J
ORCID
Venue
Advanced Drug Delivery Reviews
Publisher
Elsevier BV
Published
2002-10
Volume
54
Issue
7
Pages
889-910
ISSN
0169-409X (ISSN-L)
DOI
10.1016/s0169-409x(02)00050-9
OpenAlex
W2124696441
Cited by
394
References
108
Citations by year
2026: 7 · 2025: 6 · 2024: 9 · 2023: 15 · 2022: 21 · 2021: 14 · 2020: 19 · 2019: 13 · 2018: 18 · 2017: 18 · 2016: 21 · 2015: 26 · 2014: 22 · 2013: 21 · 2012: 27
FWCI
0.87
Type
journal article
Language
en
Open access
closed
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations
  • Advanced Drug Delivery Reviews (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Physical Sciences › Materials Science › Biomaterials › biodegradable polymer synthesis and properties
  • Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmaceutical Science › Advanced Drug Delivery Systems
  • Physical Sciences › Materials Science › Biomaterials › Hydrogels: synthesis, properties, applications
Keywords
polyanhydrides, biodegradable polymers, drug delivery, biocompatibility, in vivo degradation, toxicity, polymer synthesis, poly(ortho esters), biomaterials
MeSH terms
Anhydrides, Animals, Drug Carriers, Humans, Polymers, Drug Delivery Systems

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