The DOI matches its Crossref record; 20 of the 20 references it cites were found in a registry or an index.
The impact of psoriasis on the quality of life of patients from the 16-center PUVA follow-up cohort
Abstract
Background The impact of psoriasis on the quality of life of patients is likely to be principally related to alterations in individual appearance and consequent psychosocial disability. Quantifying the impact of psoriasis and related changes from therapy would help in the selection of optimal management.Objective Our purpose was to evaluate the impact of psoriasis on patients with severe disease who have had photochemotherapy (PUVA).Methods In 1979 we interviewed 877 of 988 still participating patients who were enrolled in 15 of 16 centers in the PUVA Follow-up Study. We determined the impact of psoriasis on quality of life with a questionnaire that had been modified to incorporate measures of impairment that are likely to be affected by cutaneous disease.Results Psoriasis had substantial impact on the quality of life. Women were more likely than men to report impairment in quality of life dimensions. The impact of disease decreased with increasing age. Moderate to high relative impact on total quality of life was more often reported by patients who had recently used UVB phototherapy than by those using PUVA or methotrexate.Conclusion Psoriasis has a substantial impact on the quality of life. This impact seems to decrease with increasing age. Use of specific treatments are also associated with the extent to which psoriasis affects quality of life.
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“Difficulties adjusting to an altered appearance can lead to anxiety, shame, reduced self-worth, social avoidance and isolation which can significantly interfere with social, occupational and relational functioning, lowering quality of life for some individuals [8-12].”
From The role of psychological flexibility in appearance anxiety in people who have experienced a visible burn injury. (2019) · cites this paper as [12]
Citations
Cites
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The effect of severe psoriasis on the quality of life of 369 patients
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Oral Methoxsalen Photochemotherapy for The Treatment of Psoriasis: a Cooperative Clinical Trial
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Cutaneous Squamous-Cell Carcinoma in Patients Treated with PUVA
Stern, R. S., Laird, N. M., Melski, J. W., Parrish, J. A., Fitzpatrick, T. B., & Bleich, H. L. (1984) · New England Journal of Medicine · doi:10.1056/nejm198405033101805 · Cited by 450
Self-citationSkin disease and handicap: An analysis of the impact of skin conditions
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Psoriasis-an index of disability
Finlay, A. Y., & Kelly, S. (1987) · Clinical and Experimental Dermatology · doi:10.1111/j.1365-2230.1987.tb01844.x · Cited by 337
The carcinogenic risk of treatments for severe psoriasis
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Krueger, G. G., Koo, J. Y. M., Lebwohl, M., Menter, A., Stern, R. S., & Rolstad, T. (2001) · PubMed · Cited by 969
Self-citationSchmitt, J. M., & Wozel, G. (2005) · Dermatology · doi:10.1159/000083509 · Cited by 443
Quality of Life in Patients with Psoriasis: A Systematic Literature Review
de Korte, J., Mombers, F. M. C., Bos, J. D., & Sprangers, M. A. G. (2004) · Journal of Investigative Dermatology Symposium Proceedings · doi:10.1046/j.1087-0024.2003.09110.x · Cited by 442
Efalizumab for Patients With Moderate to Severe Plaque Psoriasis
Gordon, K. B., Papp, K. A., Hamilton, T. K., Walicke, P. A., Dummer, W., Li, N., Bresnahan, B. W., Menter, A., & for the Efalizumab Study Group (2003) · JAMA · doi:10.1001/jama.290.23.3073 · Cited by 389
Mattei, P. L., Corey, K. C., & Kimball, A. B. (2013) · Journal of the European Academy of Dermatology and Venereology · doi:10.1111/jdv.12106 · Cited by 357
Metadata
- Authors
- McKenna, K. E., & Stern, R. S.
- Affiliations
- Harvard University (US)
- Corresponding author
- Stern, R.S.
- ORCID
- Stern, R.S.
- Venue
- Journal of the American Academy of Dermatology
- Publisher
- Elsevier BV
- Published
- 1997-03
- Volume
- 36
- Issue
- 3
- Pages
- 388-394
- ISSN
- 0190-9622 (ISSN-L)
- OpenAlex
- W2010292044
- Cited by
- 119
- References
- 20
- Citations by year
- 2026: 1 · 2025: 1 · 2024: 5 · 2023: 3 · 2022: 3 · 2021: 2 · 2020: 6 · 2019: 3 · 2018: 6 · 2017: 1 · 2016: 9 · 2015: 3 · 2014: 3 · 2013: 8 · 2012: 1
- FWCI
- 1.45
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of the American Academy of Dermatology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (N01-AR-4-2214)
- Topics
- Life Sciences › Immunology and Microbiology › Immunology › Psoriasis: Treatment and Pathogenesis
- Health Sciences › Medicine › Dermatology › Dermatology and Skin Diseases
- Health Sciences › Medicine › Rheumatology › Spondyloarthritis Studies and Treatments
- Keywords
- psoriasis, quality of life, photochemotherapy, PUVA, UVB phototherapy, methotrexate, psychosocial disability, sex differences, age differences
- MeSH terms
- Aged, Attitude to Health, Female, Humans, Male, Middle Aged, Psoriasis, PUVA Therapy, Quality of Life, Surveys and Questionnaires, Ultraviolet Therapy
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