Cited by 6Ultrasound Imaging and ElastographyPhotoacoustic and Ultrasonic ImagingUltrasound and Hyperthermia Applications

On the relationship between power mode and pressure amplitude decorrelation

Adler, Ronald S·2001·Ultrasound in Medicine & Biology

Abstract

Estimation of mean transit time, along with tissue blood volume, are important factors in determining soft tissue perfusion. Recently, power mode decorrelation techniques have been successfully used to estimate mean transit time of red blood cells or contrast material through a region-of-interest (ROI) both in laminar flow phantoms and in vivo. The previously described theory for power mode decorrelation derives from a phenomenological stochastic differential equation (Langevin equation) based on conservation of matter, relating the detected signal power to the measured rate of decorrelation. Given the experimental support for power mode decorrelation as a method to estimate mean transit time, it becomes important to determine the relationship between the phenomenological parameters that appear in the corresponding stochastic equation and system parameters, such as the transducer point response function. With this equation as a starting point, and using the fact that the pressure amplitude is a Gaussianly distributed random process, the following stochastic differential equation for the pressure amplitude p(t) is derived, a necessary first step in establishing the relationship between the measured decorrelation rate and system parameters (i.e., point response function): dp(t)/dt = -(v/2+2ik x v)p(t)+f(t), where v/2 represents the rate of decorrelation, 2k x v is the Doppler shift for an insonating wave vector k and particle velocity v.f(t) is a stationary, white noise Gaussian random process.

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Crossref · 10.1016/s0301-5629(01)00425-2

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Authors
Adler, R. S.
Affiliations
Hospital for Special Surgery (US)
Corresponding author
Adler, Ronald S
Venue
Ultrasound in Medicine & Biology
Publisher
Elsevier BV
Published
2001-09
Volume
27
Issue
9
Pages
1291-1296
ISSN
0301-5629 (ISSN-L)
OpenAlex
W1980188806
Cited by
6
References
25
Citations by year
2026: 1 · 2019: 1 · 2017: 1
FWCI
0.00
Type
journal article
Language
en
Open access
closed
Locations
  • Ultrasound in Medicine & Biology (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Ultrasound Imaging and Elastography
  • Physical Sciences › Engineering › Biomedical Engineering › Photoacoustic and Ultrasonic Imaging
  • Physical Sciences › Engineering › Biomedical Engineering › Ultrasound and Hyperthermia Applications
Keywords
mean transit time, tissue blood volume, stochastic differential equations, Langevin equation, point response function, Doppler shift, Gaussian processes, white noise, red blood cell flow, contrast-enhanced ultrasound
MeSH terms
Blood Pressure, Blood Volume, Cardiovascular Diseases, Humans, Mathematical Computing, Stochastic Processes, Ultrasonography

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