Menstrual cycle modulation of tender points
Abstract
Changes in pain sensitivity throughout the menstrual cycle were assessed in 36 normally menstruating women and 30 users of oral contraceptives. Pain sensitivity was measured with palpation of rheumatological tender points and with pressure dolorimetry. The number of tender points identified by palpation was greater in the follicular (postmenstrual) phase of the cycle as compared to the luteal (intermenstrual) phase in normally cycling women but not in users of oral contraceptives. These findings are related to previously described physiological and psychological features of the menstrual cycle, with particular emphasis on the role of hormonal events in modulating pain perception, particularly in musculoskeletal disorders such as fibromyalgia.
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A recent study found that depression was associated with patient-physician discordance in estimates of disease severity, with depressed patients estimating their disease as much worse than physicians did.
“a recent study revealed that depression was associated with patient-physician discordance in estimates of disease severity (i.e., depressed patients estimated their disease severity as much worse, on average, than their physicians did) 146.”
From Evaluating psychosocial contributions to chronic pain outcomes (2018) · cites this paper as [146]
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References 76 · Cited by 115
- Authors
- Hapidou, E. G., & Rollman, G. B.
- Affiliations
- Western University (CA)
- Corresponding author
- Hapidou, Eleni G.
- ORCID
- Hapidou, Eleni G.
- Venue
- Pain
- Published
- 1998-08
- Volume
- 77
- Issue
- 2
- Pages
- 151-161
- ISSN
- 0304-3959 (ISSN-L)
- OpenAlex
- W1970996280
- Cited by
- 115
- References
- 76
- Citations by year
- 2025: 3 · 2023: 2 · 2021: 1 · 2020: 1 · 2019: 2 · 2018: 4 · 2017: 1 · 2016: 1 · 2015: 4 · 2014: 1 · 2013: 4 · 2012: 3
- FWCI
- 6.50
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Pain (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Arthritis Society
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Fibromyalgia and Chronic Fatigue Syndrome Research
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Menstrual Health and Disorders
- Health Sciences › Medicine › Physiology › Pain Mechanisms and Treatments
- Keywords
- menstrual cycle, tender points, pain sensitivity, oral contraceptives, follicular phase, luteal phase, fibromyalgia, musculoskeletal pain, women
- MeSH terms
- Adult, Contraceptives, Oral, Female, Fibromyalgia, Humans, Menstrual Cycle, Pain, Palpation, Pain Threshold, Muscle, Skeletal
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