A natural flavonoid present in unripe plantain banana pulp (Musa sapientum L. var. paradisiaca) protects the gastric mucosa from aspirin-induced erosions
Abstract
The active anti-ulcerogenic ingredient was extracted from unripe plantain banana by solvent fractionation and identified by chromatography, spectroscopy and high performance liquid chromatography as the flavonoid leucocyanidin. Dried unripe plantain banana powder, the extracted leucocyanidin and a purified synthetic leucocyanidin demonstrated a significant (P < 0.05) protective effect against aspirin-induced erosions.
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Phenolic compounds are effectively used as functional ingredients in prevention of lipid oxidation and inhibit microbial growth.
“These compounds are effectively used as functional ingredients in the prevention of lipid oxidation [101] and inhibit microbial growth [102].”
From Functional, nutritional and medicinal potential of banana peel (2023) · cites this paper as [102]
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References 11 · Cited by 154
- Authors
- Lewis, D. A., Fields, W. N., & Shaw, G. P.
- Affiliations
- Aston University (GB)
- London Metropolitan University (GB)
- Corresponding author
- Shaw, Graham P
- ORCID
- Lewis, David A
- Venue
- Journal of Ethnopharmacology
- Publisher
- Elsevier BV
- Published
- 1999-06
- Volume
- 65
- Issue
- 3
- Pages
- 283-288
- ISSN
- 0378-8741 (ISSN-L)
- OpenAlex
- W2024693397
- Cited by
- 154
- References
- 11
- Citations by year
- 2026: 3 · 2025: 5 · 2024: 4 · 2023: 4 · 2022: 8 · 2021: 5 · 2020: 6 · 2019: 9 · 2018: 5 · 2017: 7 · 2016: 9 · 2015: 4 · 2014: 11 · 2013: 12 · 2012: 10
- FWCI
- 1.77
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Ethnopharmacology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Biochemistry › Phytochemicals and Antioxidant Activities
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Medicinal Plant Research
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Bioactive natural compounds
- Keywords
- leucocyanidin, flavonoids, Musa paradisiaca, gastroprotection, antiulcer activity, solvent fractionation
- MeSH terms
- Animals, Anti-Ulcer Agents, Aspirin, Chromatography, High Pressure Liquid, Flavonoids, Fruit, Gastric Mucosa, Gastritis, Male, Rats, Wistar, Rats
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