Seborrheic dermatitis
Abstract
Seborrheic dermatitis is present in 1% to 3% of immunocompetent adults, and is more prevalent in men than in women. Seborrheic dermatitis may be seen in conjunction with other skin diseases, such as rosacea, blepharitis or ocular rosacea, and acne vulgaris. Malassezia yeasts have been associated with seborrheic dermatitis. Abnormal or inflammatory immune system reactions to these yeasts may be related to development of seborrheic dermatitis. Treatment modalities for seborrheic dermatitis include keratolytic agents, corticosteroids, and more recently, antifungal agents. Antifungal agents do not carry a risk of skin atrophy or telangiectasia with prolonged use, and it is more prudent to consider antifungals than corticosteroid preparations. The wide range of antifungal formulations available (creams, shampoos, or oral) provides safe, effective, and flexible treatment options for seborrheic dermatitis.
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The incidence of SD among HIV patients ranges from 30% to 83%.
“The incidence among HIV patients ranges from 30% to 83% [9,10].”
From Seborrheic Dermatitis and Dandruff: A Comprehensive Review (2015) · cites this paper as [9]
Incidence of SD in the general adult population is 1-3%.
“Incidence is 1–3% of the general adult population [3,9].”
From Seborrheic Dermatitis and Dandruff: A Comprehensive Review (2015) · cites this paper as [9]
Both the incidence and severity of SD are associated with immune-suppression, particularly in HIV/AIDS patients.
“Both the incidence and severity of SD are associated with immune-suppression, particularly in HIV/AIDS patients.”
From Seborrheic Dermatitis and Dandruff: A Comprehensive Review (2015) · cites this paper as [9]
No clear differences were found in Malassezia levels between individuals with and without SD in the HIV/AIDS population, so an immune or inflammatory reaction could be the predisposition.
“Because no clear differences were found in Malassezia levels between individuals with and without SD in this population, it is likely that an immune or inflammatory reaction could be the predisposition [5,9].”
From Seborrheic Dermatitis and Dandruff: A Comprehensive Review (2015) · cites this paper as [9]
SD and dandruff have a strong time correlation with sebaceous gland activity, with cradle cap after birth, increased incidence throughout the teens, between third and sixth decades, and then decreasing.
“Thus, SD and dandruff have a strong time correlation with SG activity, with cradle cap after birth, increased incidence throughout the teens, between third and sixth decades and then decreasing [3,4,9].”
From Seborrheic Dermatitis and Dandruff: A Comprehensive Review (2015) · cites this paper as [9]
Cites
Faergemann, J., Bergbrant, I.-M., Dohsé, M., Scott, A., & Westgate, G. (2001) · British Journal of Dermatology · doi:10.1046/j.1365-2133.2001.04082.x · Cited by 173 · see citing works
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Seborrheic Dermatitis and Dandruff: A Comprehensive Review
(2015) · Journal of Clinical and Investigative Dermatology · doi:10.13188/2373-1044.1000019 · Cited by 398 · see citing works
The Role of Moisturizers in Addressing Various Kinds of Dermatitis: A Review
Purnamawati, S., Indrastuti, N., Danarti, R., & Saefudin, T. (2017) · Clinical Medicine & Research · doi:10.3121/cmr.2017.1363 · Cited by 340 · see citing works
- Authors
- Gupta, A. K., Bluhm, R., Cooper, E. A., Summerbell, R. C., & Batra, R.
- Affiliations
- Sunnybrook Health Science Centre (CA)
- Western University (CA)
- Mediprobe Research (Canada) (CA)
- Westerdijk Fungal Biodiversity Institute (NL)
- Corresponding author
- Gupta, Aditya K
- Venue
- Dermatologic Clinics
- Publisher
- Elsevier BV
- Published
- 2003-07
- Volume
- 21
- Issue
- 3
- Pages
- 401-412
- ISSN
- 0733-8635 (ISSN-L)
- OpenAlex
- W4245438413
- Cited by
- 137
- References
- 1
- Citations by year
- 2026: 5 · 2025: 7 · 2024: 5 · 2023: 6 · 2022: 11 · 2021: 6 · 2020: 7 · 2019: 12 · 2018: 3 · 2017: 6 · 2016: 4 · 2015: 9 · 2014: 4 · 2013: 7 · 2012: 6
- FWCI
- 0.55
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Dermatologic Clinics (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Epidemiology › Nail Diseases and Treatments
- Health Sciences › Medicine › Dermatology › Dermatology and Skin Diseases
- Health Sciences › Medicine › Urology › Hair Growth and Disorders
- Keywords
- seborrheic dermatitis, Malassezia, antifungal agents, corticosteroids, keratolytic agents, rosacea, blepharitis, acne, treatment options
- MeSH terms
- Administration, Cutaneous, Administration, Oral, Antifungal Agents, Humans, Malassezia, Dermatitis, Seborrheic
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