Neuroprotective effects of estrogens: potential mechanisms of action

Excitatory Amino Acids as a Final Common Pathway for Neurologic Disorders

Epstein, F. H., Lipton, S. A., & Rosenberg, P. A. (1994) · New England Journal of Medicine · doi:10.1056/nejm199403033300907 · Cited by 2,676

Hormone Therapy To Prevent Disease and Prolong Life in Postmenopausal Women

Grady, D., Rubin, S. M., Petitti, D. B., Fox, C. S., Black, D. M., Ettinger, B. B., Ernster, V. L., & Cummings, S. R. (1992) · Annals of Internal Medicine · doi:10.7326/0003-4819-117-12-1016 · Cited by 2,329

Excitotoxic cell death

Choi, D. W. (1992) · Journal of Neurobiology · doi:10.1002/neu.480230915 · Cited by 2,329

Postmenopausal Estrogen Therapy and Cardiovascular Disease

Stampfer, M. J., Colditz, G. A., Willett, W. C., Manson, J. E., ROSNER, B. A., Speizer, F. E., & Hennekens, C. H. (1991) · New England Journal of Medicine · doi:10.1056/nejm199109123251102 · Cited by 2,000

Effect of oestrogen during menopause on risk and age at onset of Alzheimer's disease

Tang, M., Jacobs, D. M., Stern, Y., Marder, K. S., Schofield, P., Gurland, B. J., Andrews, H., & Mayeux, R. P. (1996) · The Lancet · doi:10.1016/s0140-6736(96)03356-9 · Cited by 1,647

CREB: a Ca 2+ -Regulated Transcription Factor Phosphorylated by Calmodulin-Dependent Kinases

Sheng, M., Thompson, M. A., & Greenberg, M. E. (1991) · Science · doi:10.1126/science.1646483 · Cited by 1,498

Calcium Signaling in Neurons: Molecular Mechanisms and Cellular Consequences

Ghosh, A., & Greenberg, M. E. (1995) · Science · doi:10.1126/science.7716515 · Cited by 1,411

Cardiovascular mortality and noncontraceptive use of estrogen in women: results from the Lipid Research Clinics Program Follow-up Study.

Bush, T. L., Barrett-Connor, E. L., Cowan, L. D., Criqui, M. H., Wallace, R. B., Suchindran, C., Tyroler, H. A., & Rifkind, B. M. (1987) · Circulation · doi:10.1161/01.cir.75.6.1102 · Cited by 1,346

Membrane depolarization and calcium induce c-fos transcription via phosphorylation of transcription factor CREB

Sheng, M., McFadden, G., & Greenberg, M. E. (1990) · Neuron · doi:10.1016/0896-6273(90)90115-v · Cited by 1,076

cAMP Activates MAP Kinase and Elk-1 through a B-Raf- and Rap1-Dependent Pathway

Vossler, M. R., Yao, H. W., York, R. D., Pan, M., Rim, C. S., & Stork, P. A. (1997) · Cell · doi:10.1016/s0092-8674(00)80184-1 · Cited by 1,044

Differential role of estrogen receptor modulators in depression-like behavior and memory impairment in rats with postmenopausal diabetes

Bansal, S., & Chopra, K. (2015) · Menopause · doi:10.1097/gme.0000000000000435 · Cited by 24

High Sensitivity Measurement of Estrone and Estradiol in Serum and Plasma Using LC-MS/MS

Kushnir, M. M., Rockwood, A. L., Yue, B., & Meikle, A. W. (2009) · Methods in molecular biology · doi:10.1007/978-1-60761-459-3_20 · Cited by 26

Bcl-2 and Caspase 3 mRNA levels in the testes of gudgeon, Gobio gobio, exposed to ethinylestradiol (EE2)

Nadzialek, S., Pigneur, L., Wéron, B., & Kestemont, P. (2010) · Aquatic Toxicology · doi:10.1016/j.aquatox.2010.02.016 · Cited by 25

Estrogen-induced changes in the microtubular system correlate with a decreased susceptibility of aging neurons to beta amyloid neurotoxicity

Shah, R. M. (2003) · Molecular and Cellular Neuroscience · doi:10.1016/s1044-7431(03)00166-0 · Cited by 25

Neuroprotective Effects of Estradiol on Motoneurons in a Model of Rat Spinal Cord Embryonic Explants

Cardona-Rossinyol, A., Mir, M., Caraballo-Miralles, V., Lladó, J., & Olmos, G. (2013) · Cellular and Molecular Neurobiology · doi:10.1007/s10571-013-9908-9 · Cited by 24

Formulations of hormone therapy and risk of Parkinson's disease

Lundin, J. I., Ton, T. G. N., LaCroix, A. Z., Longstreth, W. T., Franklin, G. M., Swanson, P. D., Smith‐Weller, T., Racette, B. A., & Checkoway, H. (2014) · Movement Disorders · doi:10.1002/mds.26037 · Cited by 26

nNOS is involved in estrogen mediated neuroprotection in neuroblastoma cells

Wen, Y., Perez, E., Green, P. S., Sarkar, S. N., & Simpkins, J. W. (2004) · Neuroreport · doi:10.1097/01.wnr.0000131674.92694.96 · Cited by 24

Association of estrogen receptor alpha gene polymorphism with age at onset, general psychopathology symptoms, and therapeutic effect of schizophrenia

Wang, S., Li, W., Zhao, J., Zhang, H., Yang, Y., Wang, X., Ge, Y., & Lv, L. (2013) · Behavioral and Brain Functions · doi:10.1186/1744-9081-9-12 · Cited by 23

Estrogen receptor alpha and beta are both involved in the cerebral VEGF/Akt/NO pathway and cerebral angiogenesis in female mice

Jesmin, S., Mowa, C. N., Sultana, S. N., Mia, S., Islam, M. R., Zaedi, S., Sakuma, I., Hattori, Y., Hiroe, M., & Yamaguchi, N. (2010) · Biomedical Research · doi:10.2220/biomedres.31.337 · Cited by 23

17Beta-estradiol attenuates programmed cell death in cortical pericontusional zone following traumatic brain injury via upregulation of ERalpha and inhibition of caspase-3 activation

Li, L., Bao, Y., & Zhao, M. (2010) · Neurochemistry International · doi:10.1016/j.neuint.2010.11.006 · Cited by 23

Direct binding of estradiol enhances Slack (sequence like a calcium-activated potassium channel) channels’ activity

Zhang, L., Sukhareva, M., Barker, J. L., Maric, D., Hao, Y., Chang, Y. H., Ma, W., O’Shaughnessy, T. J., & Rubinow, D. R. (2005) · Neuroscience · doi:10.1016/j.neuroscience.2004.10.042 · Cited by 23

Neuritogenic and Neuroprotective Effects of Polar Steroids from the Far East Starfishes Patiria pectinifera and Distolasterias nipon

Palyanova, N. V., Pankova, T., Starostina, M. V., Kicha, A. A., Ivanchina, N. V., & Stonik, V. A. (2013) · Marine Drugs · doi:10.3390/md11051440 · Cited by 23

Oestradiol attenuates the cognitive deficit induced by acute phencyclidine treatment in mature female hooded-Lister rats

Sutcliffe, J., Rhaman, F., Marshall, K. M., & Neill, J. C. (2008) · Journal of Psychopharmacology · doi:10.1177/0269881107083839 · Cited by 23

Lactulose: an effective preventive and therapeutic option for ischemic stroke by production of hydrogen

Chen, X., Zhai, X., Kang, Z., & Sun, X. (2012) · Medical Gas Research · doi:10.1186/2045-9912-2-3 · Cited by 23

Mechanisms of protein misfolding: Novel therapeutic approaches to protein-misfolding diseases

Salahuddin, P., Siddiqi, M. K., Khan, S., Abdelhameed, A. S., & Khan, R. H. (2016) · Journal of Molecular Structure · doi:10.1016/j.molstruc.2016.06.046 · Cited by 23

Late Menarche, Not Reproductive Period, Is Associated with Poor Cognitive Function in Postmenopausal Women in Taiwan

Chou, H.-T., Wu, P.-Y., Huang, J., Chen, S., & Ho, W. (2021) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph18052345 · Cited by 23

Protective effect of 17-β-estradiol in human neurocellular models of lead exposure

Chetty, C. S., Vemuri, M. C., Reddy, G. R., & Challa, S. (2006) · NeuroToxicology · doi:10.1016/j.neuro.2006.03.012 · Cited by 23

The effects of soy isoflavone on bone density in north region of climacteric Chinese women

Chi, X., & Zhang, T. (2013) · Journal of Clinical Biochemistry and Nutrition · doi:10.3164/jcbn.13-37 · Cited by 23

Are gonadal steroid hormones involved in disorders of brain aging?

Azcoitia, Í., DonCarlos, L. L., & García‐Segura, L. M. (2003) · Aging Cell · doi:10.1046/j.1474-9728.2003.00013.x · Cited by 23

Tamoxifen protects clonal mouse hippocampal (HT-22) cells against neurotoxins-induced cell death

Gursoy, E. C., Cardounel, A. J., Al-khlaiwi, T., AlDrees, A., & Kalimi, M. (2002) · Neurochemistry International · doi:10.1016/s0197-0186(01)00105-x · Cited by 23

Preventive Effects of Soy Meal (±Isoflavone) on Spatial Cognitive Deficiency and Body Weight in an Ovariectomized Animal Model of Parkinson's Disease

Sarkaki, A., Badavi, M., Aligholi, H., & Moghaddam, A. Z. (2009) · Pakistan Journal of Biological Sciences · doi:10.3923/pjbs.2009.1338.1345 · Cited by 22

High-Sensitivity Micro LC-MS/MS Assay for Serum Estradiol without Derivatization

Yi, X., Leung, E. K. Y., Bridgman, R., Koo, S. C., & Yeo, K.-T. J. (2016) · The Journal of Applied Laboratory Medicine · doi:10.1373/jalm.2016.020362 · Cited by 22

17β-Estradiol Modulates Gene Expression in the Female Mouse Cerebral Cortex

Humphreys, G. I., Ziegler, Y., & Nardulli, A. M. (2014) · PLoS ONE · doi:10.1371/journal.pone.0111975 · Cited by 24

Neuroprotective effects of estradiol-17β: implications for psychiatric disorders

Kölsch, H., & Rao, M. L. (2002) · Archives of Women s Mental Health · doi:10.1007/s00737-002-0005-1 · Cited by 22

Can estrogen play a significant role in the prevention of Alzheimer’s disease?

Kesslak, J. P. (2002) · Journal of neural transmission. Supplementum · doi:10.1007/978-3-7091-6139-5_21 · Cited by 22

Long-term ovariectomy increases BDNF gene methylation status in mouse hippocampus

Moreno-Piovano, G. S., Varayoud, J., Luque, E. H., & Ramos, J. G. (2014) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2014.08.001 · Cited by 21

Involvement of stat3 in mouse brain development and sexual dimorphism: A proteomics approach

Domenico, F. D., Casalena, G., Rukhsana Sultana, A., Cai, J., Pierce, W. M. J., Marzia Perluigi, A., Cini, C., Baracca, A., Solaini, G., Lenaz, G., et al. (2010) · Brain Research · doi:10.1016/j.brainres.2010.09.074 · Cited by 21

Oxidative Stress and 17-α- and 17-β-Estradiol Modulate Neurofilaments Differently

Chiasson, K., Lahaie-Collins, V., Bournival, J., Delapierre, B., Gélinas, S., & Martinoli, M. (2006) · Journal of Molecular Neuroscience · doi:10.1385/jmn:30:3:297 · Cited by 21

Ovariectomy impairs spatial memory: prevention and reversal by a soy isoflavone diet

Monteiro, S., de Mattos, C. D., Ben, J., Netto, C., & Wyse, A. (2008) · Metabolic brain disease · doi:10.1007/s11011-008-9093-6 · Cited by 25

Estrogen Receptor Alpha Inhibits the Estrogen-Mediated Suppression of HIV Transcription in Astrocytes: Implications for Estrogen Neuroprotection in HIV Dementia

Heron, P. M., Turchan-Cholewo, J. T., Bruce‐Keller, A. J., & Wilson, M. E. (2009) · AIDS Research and Human Retroviruses · doi:10.1089/aid.2009.0065 · Cited by 20

Oxidative Stress and the Metabolic Pathology of Autism

James, S. J. (2008) · Humana Press eBooks · doi:10.1007/978-1-60327-489-0_11 · Cited by 20

ER‐β mediates 17β‐estradiol attenuation of HIV‐1 Tat‐induced apoptotic signaling

Adams, S. M., Aksenova, M. V., Aksenov, M. Y., Mactutus, C. F., & Booze, R. M. (2010) · Synapse · doi:10.1002/syn.20793 · Cited by 20

Sarcopenia is more than a muscular deficit.

Fulle, S., Belia, S., & Tano, G. D. (2005) · PubMed · Cited by 20

Sex and steroid hormones in early brain injury

Nuñez, J. L. (2012) · Reviews in Endocrine and Metabolic Disorders · doi:10.1007/s11154-012-9219-3 · Cited by 19

New Targets of Neuroprotection in Ischemic Stroke

Bacigaluppi, M., & Hermann, D. M. (2008) · The Scientific World JOURNAL · doi:10.1100/tsw.2008.94 · Cited by 19

Estrogen attenuates hypoxic–ischemic brain injury in neonatal rats

Feng, Y., Fratkins, J. D., & LeBlanc, M. H. (2005) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2004.11.039 · Cited by 19

Effect of isoflavone administration on age-related hepatocyte changes in old ovariectomized femal Wistar rats

Castillo, C., Salazar, V., Ariznavarreta, C., Vara, E., & Tresguerres, J. A. F. (2005) · Phytomedicine · doi:10.1016/j.phymed.2005.03.012 · Cited by 19

Long‐term exposure of 3T3 fibroblast cells to endocrine disruptors alters sensitivity to oxidative injury

Nishimura, Y., Nakai, Y., Tanaka, A., Nagao, T., & Fukushima, N. (2014) · Cell Biology International · doi:10.1002/cbin.10269 · Cited by 18

Pulmonary antioxidant defences and protein damage during the ageing process of both sexes

Hackenhaar, F. S., Salomon, T. B., Alabarse, P. V. G., Ehrenbrink, G., & Benfato, M. S. (2009) · Cell Biochemistry and Function · doi:10.1002/cbf.1585 · Cited by 18

Is pharmacological prevention of Alzheimer's a realistic goal?

Anthony, J. C., Breitner, J. C. S., & Zandi, P. P. (2002) · Expert Opinion on Pharmacotherapy · doi:10.1517/14656566.3.4.365 · Cited by 18

17β-Estradiol attenuates secondary injury through activation of Akt signaling via estrogen receptor alpha in rat brain following subarachnoid hemorrhage

Kao, C.-H., Chang, C.-Z., Su, Y., Tsai, Y.-J., Chang, K., Lin, T.-K., Hwang, S., & Lin, C. (2013) · Journal of Surgical Research · doi:10.1016/j.jss.2013.01.033 · Cited by 17

Effects of 17β-estradiol on proliferation, cell viability and intracellular redox status in native human lens epithelial cells.

Celojevic, D., Petersen, A. H., KARLSSON, J., Behndig, A., & Zetterberg, M. (2011) · PubMed Central · Cited by 17

Pharmacological characterization of the mechanisms involved in the vasorelaxation induced by progesterone and 17β-estradiol on isolated canine basilar and internal carotid arteries

Ramirez-Rosas, M. B., Cobos-Puc, L. E., Sánchez‐López, A., Gutierrez-Lara, E. J., & Centurión, D. (2014) · Steroids · doi:10.1016/j.steroids.2014.07.010 · Cited by 17

Brain steroidogenesis: emerging therapeutic strategies to prevent neurodegeneration

Azcoitia, Í., Sierra, A., Veiga, S. J., & García‐Segura, L. M. (2004) · Journal of Neural Transmission · doi:10.1007/s00702-004-0179-y · Cited by 17

Aging and substitutive hormonal therapy influence in regional and subcellular distribution of ERα in female rat brain

Navarro, A., del Valle, E., Ordóñez, C., Martínez‐Pinilla, E., Pérez, C., Alonso, A., González, C., & Tolivia, J. (2012) · AGE · doi:10.1007/s11357-012-9415-9 · Cited by 17

Down-regulation of glutaredoxin by estrogen receptor antagonist renders female mice susceptible to excitatory amino acid mediated complex I inhibition in CNS

Diwakar, L., Kenchappa, R. S., Jayasree Annepu, B., Saeed, U., Ramakrishnan, S., & Ravindranath, V. (2006) · Brain Research · doi:10.1016/j.brainres.2006.10.015 · Cited by 17

Şizofreni Başlangıç Yaşı ile Menarş Yaşı Arasındaki İlişki

Kılıçaslan, E. E., Erol, A., Zengin, B., Aydın, P. Ç., & Mete, L. (2014) · Nöro Psikiyatri Arşivi · doi:10.4274/npa.y6675 · Cited by 17

Apolipoprotein E isoform‐specific disruption of phosphoinositide hydrolysis: protection by estrogen and glutathione

Cedazo-Mínguez, Á., & Cowburn, R. F. (2001) · FEBS Letters · doi:10.1016/s0014-5793(01)02761-2 · Cited by 17

Evaluating GLP-1 receptor agonists versus metformin as first-line therapy for reducing dementia risk in type 2 diabetes

Sun, M., Wang, X., Lu, Z., Yang, Y., Lv, S., Miao, M., Chen, W., Wu, S., & Zhang, J. (2025) · BMJ Open Diabetes Research & Care · doi:10.1136/bmjdrc-2025-004902 · Cited by 17

Mitochondrial estrogen receptors as a vulnerability factor of chronic stress and mediator of fluoxetine treatment in female and male rat hippocampus

Adžić, M., Mitić, M., & Radojcic, M. B. (2017) · Brain Research · doi:10.1016/j.brainres.2017.07.007 · Cited by 16

A novel mechanism of non-feminizing estrogens in neuroprotection

Engler-Chiurazzi, E. B., Covey, D. F., & Simpkins, J. W. (2016) · Experimental Gerontology · doi:10.1016/j.exger.2016.10.013 · Cited by 16

Role of protein kinase C in estrogen protection against apoptotic cerebellar cell death in ethanol-withdrawn rats

Jung, M. E., Watson, D. G., Wen, Y., & Simpkins, J. W. (2003) · Alcohol · doi:10.1016/j.alcohol.2003.07.004 · Cited by 16

Breast cancer therapies reduce risk of Alzheimer’s disease and promote estrogenic pathways and action in brain

Branigan, G. L., Torrandell‐Haro, G., Chen, S., Shang, Y., Perez‐Miller, S., Mao, Z., Padilla‐Rodriguez, M., Cortes‐Flores, H., Vitali, F., & Brinton, R. D. (2023) · iScience · doi:10.1016/j.isci.2023.108316 · Cited by 15

17β-Estradiol Downregulated the Expression of TASK-1 Channels in Mouse Neuroblastoma N2A Cells

Hao, X., Li, X., & Li, X. (2014) · The Journal of Membrane Biology · doi:10.1007/s00232-014-9632-5 · Cited by 15

Neuroprotective role of estrogens relationship with insulin IGF-1 signaling

González, C. (2012) · Frontiers in Bioscience-Elite · doi:10.2741/e403 · Cited by 15

Overexpression of Tau Downregulated the mRNA Levels of Kv Channels and Improved Proliferation in N2A Cells

Li, X., Hu, X.-M., Li, X., & Hao, X. (2015) · PLoS ONE · doi:10.1371/journal.pone.0116628 · Cited by 15

Endogenous Repair by the Activation of Cell Survival Signalling Cascades during the Early Stages of Rat Parkinsonism

Lui, N.-P., Chen, L., Yung, W., Chan, Y., & Yung, K. K. L. (2012) · PLoS ONE · doi:10.1371/journal.pone.0051294 · Cited by 15

Comparison of estrogen-derived ortho-quinone and para-quinol concerning induction of oxidative stress

Rivera‐Portalatin, N. M., Vera‐Serrano, J. L., Prókai-Tátrai, K., & Prókai, L. (2007) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2006.11.025 · Cited by 16

Increased Levels of Superoxide in Brains from Old Female Rats

Antier, D., Carswell, H. V. O., Brosnan, M. J., Hamilton, C. A., Macrae, I. M., Groves, S., Jardine, E., Reid, J. L., & Dominiczak, A. F. (2003) · Free Radical Research · doi:10.1080/10715760310001643294 · Cited by 15

Changes in the content and distribution of microtubule associated protein 2 in the hippocampus of the rat during the estrous cycle

Reyna‐Neyra, A., Arias, C., Ferrera, P., Morimoto, S., & Camacho‐Arroyo, I. (2004) · Journal of Neurobiology · doi:10.1002/neu.20042 · Cited by 15

Regional Brain Volume, Brain Reserve and MMSE Performance in Healthy Aging From the NEUROAGE Cohort: Contributions of Sex, Education, and Depression Symptoms

Pettemeridou, E., Kallousia, E., & Constantinidou, F. (2021) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2021.711301 · Cited by 14

A mechanical acupuncture instrument mitigates the endoplasmic reticulum stress and oxidative stress of ovariectomized rats

Seo, S. Y., Kang, S.-Y., Kwon, O. S., Bang, S. K., Kim, S. P., Choi, K., Moon, J. Y., & Ryu, Y. (2019) · Integrative Medicine Research · doi:10.1016/j.imr.2019.07.001 · Cited by 14

Estradiol increases expression of the brain-derived neurotrophic factor after acute administration of ethanol in the neonatal rat cerebellum

Firouzan, B., Goudarzi, I., Salmani, M. E., Lashkarbolouki, T., Rezaei, A., & Abrari, K. (2014) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2014.02.041 · Cited by 14

Supplementation with vitamins E plus C or soy isoflavones in ovariectomized rats: effect on the activities of Na+, K+-ATPase and cholinesterases

Monteiro, S. C., de Mattos, C. B., Scherer, E. B. S., & Wyse, Â. T. D. S. (2007) · Metabolic Brain Disease · doi:10.1007/s11011-007-9051-8 · Cited by 14

17β-Estradiol/N-acetylcysteine interaction enhances the neuroprotective effect on dopaminergic neurons in the weaver model of dopamine deficiency

Botsakis, K., Theodoritsi, S., Grintzalis, K., Angelatou, F., Antonopoulos, I., Georgiou, C. D., Margarity, M., Matsokis, N. A., & Panagopoulos, N. T. (2016) · Neuroscience · doi:10.1016/j.neuroscience.2016.01.068 · Cited by 13

In search of sex-related mediators of affective illness

Sikes-Keilp, C., & Rubinow, D. R. (2021) · Biology of Sex Differences · doi:10.1186/s13293-021-00400-4 · Cited by 13

Effects of 17β‐oestradiol on rat detrusor smooth muscle contractility

Valeri, A., Brain, K. L., Young, J. S., Sgaragli, G., & Pessina, F. (2009) · Experimental Physiology · doi:10.1113/expphysiol.2009.047118 · Cited by 13

Effects of 192 IgG-saporin on acetylcholinesterase histochemistry in male and female rats

Galani, R., Jeltsch‐David, H., Lehmann, O., Bertrand, F., & Cassel, J. (2002) · Brain Research Bulletin · doi:10.1016/s0361-9230(02)00775-x · Cited by 13

Decreased apoptosis in the forebrain of adult male medaka (Oryzias latipes) after aqueous exposure to ethinylestradiol

Stokes, E. A., Lonergan, W., Weber, L. P., Janz, D. M., Poznanski, A., Balch, G. C., Metcalfe, C. D., & Grober, M. S. (2004) · Comparative Biochemistry and Physiology Part C Toxicology & Pharmacology · doi:10.1016/j.cca.2004.06.006 · Cited by 13

Effects of 17β-estradiol on intracellular calcium changes and neuronal survival after mechanical strain injury in neuronal–glial cultures

Lapanantasin, S., Chongthammakun, S., Floyd, C. L., & Berman, R. F. (2006) · Synapse · doi:10.1002/syn.20308 · Cited by 13

Ovariectomy Enhances Acetylcholinesterase Activity But Does Not Alter Ganglioside Content in Cerebral Cortex of Female Adult Rats

Monteiro, S. C., Stefanello, F. M., Vianna, L. P., Matté, C., Barp, J., Belló‐Klein, A., Trindade, V. M. T., & Wyse, Â. T. D. S. (2005) · Metabolic Brain Disease · doi:10.1007/s11011-005-2474-1 · Cited by 13

An early treatment with 17‐β‐estradiol is neuroprotective against the long‐term effects of neonatal ionizing radiation exposure

Caceres, L. G., Uran, S. L., Zubilete, M. A. Z., Romero, J. I., Capani, F., & Guelman, L. R. (2011) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2011.07334.x · Cited by 12

Estrogen prevents β-amyloid inhibition of sympathetic α7-nAChR-mediated nitrergic neurogenic dilation in porcine basilar arteries

Si, M.-L., Long, C., Chen, M.-F., & Lee, T. J.-F. (2010) · Acta Physiologica · doi:10.1111/j.1748-1716.2010.02224.x · Cited by 12

Neuroprotective Effects of 17β-Estradiol After Hypovolemic Cardiac Arrest in Immature Piglets

Semenas, E., SHARMA, H. S., Nozari, A., Basu, S., & Wiklund, L. (2011) · Shock · doi:10.1097/shk.0b013e3182150f43 · Cited by 12

Bilingual experience and executive control over the adult lifespan: The role of biological sex

Subramaniapillai, S., Rajah, M. N., Pasvanis, S., & Titone, D. A. (2018) · Bilingualism Language and Cognition · doi:10.1017/s1366728918000317 · Cited by 14

The effects of estrogen and progesterone on blood glutamate levels during normal pregnancy in women

Tsesis, S., Gruenbaum, B. F., Ohayon, S., Boyko, M., Gruenbaum, S. E., Shapira, Y., Weintraub, A. Y., & Zlotnik, A. A. (2013) · Gynecological Endocrinology · doi:10.3109/09513590.2013.813467 · Cited by 11

Existing and emerging mitochondrial-targeting therapies for altering Parkinson's disease severity and progression

Pienaar, I. S., & Chinnery, P. F. (2012) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2012.08.010 · Cited by 11

Effect of estrogen therapy on cerebral arteries during stroke in female rats

Goodrow, G. J., Vitullo, L., & Cipolla, M. J. (2005) · Menopause The Journal of The North American Menopause Society · doi:10.1097/00042192-200512010-00017 · Cited by 11

Neuroprotection with non-feminizing estrogen analogues: An overlooked possible therapeutic strategy

Simpkins, J. W., Richardson, T. E., Yi, K. D., Perez, E., & Covey, D. F. (2012) · Hormones and Behavior · doi:10.1016/j.yhbeh.2012.03.013 · Cited by 11

Oestrogen has neuroprotective effects and may reduce the risk of Alzheimer’s disease

Eberling, J. L. (2002) · Expert Opinion on Biological Therapy · doi:10.1517/14712598.2.6.647 · Cited by 11

Suppression of protein kinase Cε mediates 17β‐estradiol‐induced neuroprotection in an immortalized hippocampal cell line

Jung, M., Watson, D. G., & Simpkins, J. W. (2005) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2005.03424.x · Cited by 10

Neuroprotective Strategies in Alzheimer’s Disease

Behl, C. (2003) · Advances in experimental medicine and biology · doi:10.1007/978-1-4615-0123-7_18 · Cited by 11

Effect of 17-β-estradiol on dopamine, serotonine and GABA striatal levels in 6-hydroxydopamine-treated rats

Peinado, V., Gonzalez, J., & Leret, M. L. (2004) · Toxicology · doi:10.1016/j.tox.2004.06.021 · Cited by 11

Potential Use of Estrogen-Like Drugs for the Prevention of Alzheimer's Disease

Smith, J. D., & Levin-Allerhand, J. A. (2003) · Journal of Molecular Neuroscience · doi:10.1385/jmn:20:3:277 · Cited by 11

Amyloid precursor protein 17-mer peptide ameliorates hippocampal neurodegeneration in ovariectomized rats

Meng, Y., Wang, R., Fang, Y., Ji, Z., Fang, L., & Sheng, S. (2009) · Neuroscience Letters · doi:10.1016/j.neulet.2009.07.058 · Cited by 10

Ferula hermonis: A Review of Current Use and Pharmacological Studies of its Sesquiterpene Ester Ferutinin

Safi, R., El-Sabban, M. E., & Najjar, F. (2019) · Current Drug Targets · doi:10.2174/1389450120666191029155053 · Cited by 10

Age-related changes of apolipoprotein D expression in female rat central nervous system with chronic estradiol treatment

Pérez, C., Navarro, A., Martínez‐Pinilla, E., Ordóñez, C., del Valle, E., & Tolivia, J. (2011) · AGE · doi:10.1007/s11357-011-9286-5 · Cited by 10

17β-Estradiol treatment retards excitotoxic delayed degeneration in substantia nigra reticulata neurons

DeGiorgio, L. A., Attardi, B., Shimizu, Y., Ogata, M., & Volpe, B. T. (2002) · Brain Research · doi:10.1016/s0006-8993(02)02482-4 · Cited by 10

Estrogen Replacement Therapy for Stroke

Pabon, M. M., Tamboli, C., Tamboli, S., Acosta, S., de la Peña, I., Sanberg, P. R., Tajiri, N., Kaneko, Y., & Borlongan, C. V. (2013) · Cell Medicine · doi:10.3727/215517913x672263 · Cited by 10

Peripheral vs. Central Sex Steroid Hormones in Experimental Parkinson?s Disease

McArthur, S., & Gillies, G. E. (2011) · Frontiers in Endocrinology · doi:10.3389/fendo.2011.00082 · Cited by 10

Partial neuroprotection by 17-β-estradiol in neonatal gamma-irradiated rat cerebellum

Zubilete, M. A. Z., Guelman, L. R., Maur, D. G., Caceres, L. G., Rı́os, H., Zieher, L. M., & Genaro, A. M. (2010) · Neurochemistry International · doi:10.1016/j.neuint.2010.11.020 · Cited by 10

Estrogens and Cerebrovascular Stroke: What Do Animal Models Teach Us?

Wise, P. M. (2005) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1347.017 · Cited by 10

Exogenous estradiol enhances apoptosis in regressing post-partum rat corpora lutea possibly mediated by prolactin

Goyeneche, A. A., & Telleria, C. M. (2005) · Reproductive Biology and Endocrinology · doi:10.1186/1477-7827-3-40 · Cited by 10

The effects of dietary choline

Biasi, E. (2011) · Neuroscience Bulletin · doi:10.1007/s12264-011-1523-5 · Cited by 10

Estrogens in Neuropsychiatric Disorders: From Physiology to Pathophysiology

Vedder, H., & Behl, C. (2005) · Springer eBooks · doi:10.1007/3-211-27063-9_1 · Cited by 10

7β-hydroxy-epiandrosterone modulation of 15-deoxy-Δ12,14-prostaglandin J2, prostaglandin D2 and prostaglandin E2 production from human mononuclear cells

Davidson, J., Wülfert, E., & Rotondo, D. (2008) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2008.10.007 · Cited by 9

Associations Among Pregnancy, Parturition, and Open-angle Glaucoma: Korea National Health and Nutrition Examination Survey 2010 to 2011

Lee, J. Y., Kim, J. M., Kim, S. H., Kim, I. T., Kim, H. T., Chung, P., Bae, J. H., Won, Y. S., Lee, M. Y., & Park, K. H. (2018) · Journal of Glaucoma · doi:10.1097/ijg.0000000000001101 · Cited by 9

Pro-social and anxiolytic-like behavior following a single 24-h exposure to 17β-estradiol in adult male zebrafish

Moraes, A. B., Giacomini, A. C. V. V., Genário, R., Marcon, L., Scolari, N., Bueno, B. W., Demin, K. A., Amstislavskaya, T. G., Strekalova, T. V., Soares, M. C., et al. (2020) · Neuroscience Letters · doi:10.1016/j.neulet.2020.135591 · Cited by 9

Study of familial Parkinson’s disease in Russia, Uzbekistan, and Zambia

Atadzhanov, M., Zumla, A. I., & Mwaba, P. (2005) · Postgraduate Medical Journal · doi:10.1136/pgmj.2004.018705 · Cited by 9

Vitamin D Supplementation Reverses DNA Damage and Telomeres Shortening Caused by Ovariectomy in Hippocampus of Wistar Rats

Siebert, C., dos Santos, T. M., Bertó, C. G., Parisi, M. M., Coelho, R. P., Manfredini, V., Barbé‐Tuana, F. M., & Wyse, Â. T. D. S. (2018) · Neurotoxicity Research · doi:10.1007/s12640-018-9909-z · Cited by 9

From clinical evidence to molecular mechanisms underlying neuroprotection afforded by estrogens

Amantea, D., Russo, R., Bagetta, G., & Corasaniti, M. T. (2005) · Pharmacological Research · doi:10.1016/j.phrs.2005.03.002 · Cited by 194

Anti-oxidative neuroprotection by estrogens in mouse cortical cultures

Bae, Y. H., Hwang, J. Y., Kim, Y. H., & Koh, J. Y. (2000) · Journal of Korean Medical Science · doi:10.3346/jkms.2000.15.3.327 · Cited by 58

Influence of estrogens on neurodegenerative processes.

Członkowska, A., Ciesielska, A., & Joniec‐Maciejak, I. (2003) · PubMed · Cited by 26

Nerve Cell Protection by Estrogen: Molecular Mechanisms

Behl, C. (2001) · Springer eBooks · doi:10.1007/978-3-7091-6189-0_8

Progress on the Neuroprotective Effects of Estrogen

Li-xi, S. (2012)