Recommendations for straightforward and rigorous methods of counting neurons based on a computer simulation approach

The Art of Computer Programming

Knuth, D. E. (1968) · Cited by 16,097

The Art of Computer Programming. Volume 2: Seminumerical Algorithms.

Taussky, O., & Knuth, D. E. (1970) · American Mathematical Monthly · doi:10.2307/2317055 · Cited by 3,863

The efficiency of systematic sampling in stereology and its prediction*

Gundersen, H. J. G., & Jensen, E. B. V. (1987) · Journal of Microscopy · doi:10.1111/j.1365-2818.1987.tb02837.x · Cited by 3,519

Unbiased stereological estimation of the total number of neurons in the subdivisions of the rat hippocampus using the optical fractionator

West, M. J., Slomianka, L., & Gundersen, H. J. G. (1991) · The Anatomical Record · doi:10.1002/ar.1092310411 · Cited by 2,994

Statistical analysis of spatial point patterns

(1986) · Environmental Software · doi:10.1016/0266-9838(86)90012-2 · Cited by 2,929

The new stereological tools: Disector, fractionator, nucleator and point sampled intercepts and their use in pathological research and diagnosis

Gundersen, H. J. G., Bagger, P. V., Bendtsen, T. F., Evans, S. M., Korbo, L., Marcussen, N., Møller, A., Nielsen, K. N., Nyengaard, J. R., Pakkenberg, B., et al. (1988) · Apmis · doi:10.1111/j.1699-0463.1988.tb00954.x · Cited by 2,480

Stochastic Simulation

Ripley, B. D. (1987) · Wiley Series in Probability and Statistics · doi:10.1002/9780470316726 · Cited by 2,241

Stereology of arbitrary particles. A review of unbiased number and size estimators and the presentation of some new ones, in memory of William R. Thompson.

Gundersen, H. J. G. (1986) · PubMed · Cited by 1,658

Stereology of arbitrary particles*

Gundersen, H. J. G. (1986) · Journal of Microscopy · doi:10.1111/j.1365-2818.1986.tb02764.x · Cited by 1,444

The efficiency of systematic sampling in stereology—reconsidered

GUNDERSEN, H. J. G., JENSEN, E. B. V., KIÊU, K., & NIELSEN, J. (1999) · Journal of Microscopy · doi:10.1046/j.1365-2818.1999.00457.x · Cited by 1,317

The search for true numbers of neurons and glial cells in the human brain: A review of 150 years of cell counting

von Bartheld, C. S., Bahney, J., & Herculano‐Houzel, S. (2016) · Journal of Comparative Neurology · doi:10.1002/cne.24040 · Cited by 1,063

Design-based stereology in neuroscience.

Schmitz, C., & Hof, P. R. (2005) · Neuroscience · doi:10.1016/j.neuroscience.2004.08.050 · Cited by 681

Transient and Selective Overexpression of Dopamine D2 Receptors in the Striatum Causes Persistent Abnormalities in Prefrontal Cortex Functioning

Kellendonk, C., Simpson, E. H., Polan, H. J., Malleret, G., Vronskaya, S., Winiger, V., Moore, H., & Kandel, E. R. (2006) · Neuron · doi:10.1016/j.neuron.2006.01.023 · Cited by 520

Cell-cycle reentry and cell death in transgenic mice expressing nonmutant human tau isoforms

Andorfer, C., Acker, C. M., Kress, Y., Hof, P. R., Duff, K., & Davies, P. (2005) · The Journal of Neuroscience · doi:10.1523/jneurosci.4637-04.2005 · Cited by 511

Loss and altered spatial distribution of oligodendrocytes in the superior frontal gyrus in schizophrenia

Hof, P. R., Haroutunian, V., Friedrich, V. L., Byne, W., Buitron, C., Perl, D. P., & Davis, K. L. (2003) · Biological Psychiatry · doi:10.1016/s0006-3223(03)00237-3 · Cited by 433

Massive CA1/2 Neuronal Loss with Intraneuronal and N-Terminal Truncated Aβ42 Accumulation in a Novel Alzheimer Transgenic Model

Casas, C., Sergeant, N., Itier, J.-M., Blanchard, V., Wirths, O., van der Kolk, N., Vingtdeux, V., van de Steeg, E., Ret, G., Canton, T., et al. (2004) · The American Journal of Pathology · doi:10.1016/s0002-9440(10)63388-3 · Cited by 400

Age-associated increases of α-synuclein in monkeys and humans are associated with nigrostriatal dopamine depletion: Is this the target for Parkinson's disease?

Chu, Y., & Kordower, J. H. (2006) · Neurobiology of Disease · doi:10.1016/j.nbd.2006.08.021 · Cited by 423

Early frontotemporal dementia targets neurons unique to apes and humans

Seeley, W. W., Carlin, D. A., Allman, J. M., Macedo, M. N., Bush, C., Miller, B. L., & DeArmond, S. J. (2006) · Annals of Neurology · doi:10.1002/ana.21055 · Cited by 364

Evolution of increased glia–neuron ratios in the human frontal cortex

Sherwood, C. C., Stimpson, C. D., Raghanti, M. A., Wildman, D. E., Uddin, M., Grossman, L. I., Goodman, M., Redmond, J. C., Bonar, C. J., Erwin, J. M., et al. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0605843103 · Cited by 342

Hippocampal Neuron Loss Exceeds Amyloid Plaque Load in a Transgenic Mouse Model of Alzheimer's Disease

Schmitz, C., Rutten, B. P. F., Pielen, A., Schäfer, S., Wirths, O., Tremp, G., Czech, C., Blanchard, V., Multhaup, G., Rezaie, P., et al. (2004) · The American Journal of Pathology · doi:10.1016/s0002-9440(10)63235-x · Cited by 281

Characterization of Neurophysiological and Behavioral Changes, MRI Brain Volumetry and 1H MRS in zQ175 Knock-In Mouse Model of Huntington's Disease

Heikkinen, T., Lehtimäki, K. K., Vartiainen, N. E., Puoliväli, J. T., Hendricks, S. J., Glaser, J. R., Bradaïa, A., Wadel, K., Touller, C., Kontkanen, O., et al. (2012) · PLoS ONE · doi:10.1371/journal.pone.0050717 · Cited by 265

Neurons in the fusiform gyrus are fewer and smaller in autism

van Kooten, I. A. J., Palmen, S. J. M. C., von Cappeln, P., Steinbusch, H. W. M., Korr, H., Heinsen, H., Hof, P. R., van Engeland, H., & Schmitz, C. (2008) · Brain · doi:10.1093/brain/awn033 · Cited by 263

Depressive-like behaviors alterations induced by intranigral MPTP, 6-OHDA, LPS and rotenone models of Parkinson's disease are predominantly associated with serotonin and dopamine

Santiago, R. M., Barbieiro, J., Lima, M. M. S., Dombrowski, P. A., Andreatini, R., & Vital, M. A. B. F. (2010) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2010.06.004 · Cited by 251

Estimators of the precision of stereological estimates: An example based on the CA1 pyramidal cell layer of rats

Slomianka, L., & West, M. J. (2005) · Neuroscience · doi:10.1016/j.neuroscience.2005.06.086 · Cited by 236

Nurr1 in Parkinson's disease and related disorders

Chu, Y., Le, W., Kompoliti, K., Jankovic, J. J., Mufson, E. J., & Kordower, J. H. (2005) · The Journal of Comparative Neurology · doi:10.1002/cne.20828 · Cited by 232

Normoxic Resuscitation after Cardiac Arrest Protects against Hippocampal Oxidative Stress, Metabolic Dysfunction, and Neuronal Death

Vereczki, V., Martin, E., Rosenthal, R. E., Hof, P. R., Hoffman, G. E., & Fiskum, G. M. (2005) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/sj.jcbfm.9600234 · Cited by 213

Broca's Area Homologue in Chimpanzees (Pan troglodytes): Probabilistic Mapping, Asymmetry, and Comparison to Humans

Schenker-Ahmed, N. M., Hopkins, W. D., Spocter, M. A., Garrison, A. R., Stimpson, C. D., Erwin, J. M., Hof, P. R., & Sherwood, C. C. (2009) · Cerebral Cortex · doi:10.1093/cercor/bhp138 · Cited by 212

Oximetry-Guided Reoxygenation Improves Neurological Outcome After Experimental Cardiac Arrest

Balan, I. S., Fiskum, G. M., Hazelton, J. L., Cotto-Cumba, C., & Rosenthal, R. E. (2006) · Stroke · doi:10.1161/01.str.0000248455.73785.b1 · Cited by 205

Estrogen increases the number of spinophilin‐immunoreactive spines in the hippocampus of young and aged female rhesus monkeys

Hao, J., Janssen, W. G. M., Tang, Y. C., Roberts, J. A., McKay, H. M., Lasley, B. L., Allen, P. B., Greengard, P., Rapp, P. R., Kordower, J. H., et al. (2003) · The Journal of Comparative Neurology · doi:10.1002/cne.10837 · Cited by 200

Transplantation of Ciliary Neurotrophic Factor-Expressing Adult Oligodendrocyte Precursor Cells Promotes Remyelination and Functional Recovery after SpinalCord Injury

Cao, Q., He, Q., Wang, Y., Cheng, X., Howard, R. M., Zhang, Y., DeVries, W. H., Shields, C. B., Magnuson, D. S. K., Xu, X., et al. (2010) · Journal of Neuroscience · doi:10.1523/jneurosci.3174-09.2010 · Cited by 205

Molecular and Cellular Evidence for an Oligodendrocyte Abnormality in Schizophrenia

Hof, P. R., Haroutunian, V., Copland, C., Davis, K. L., & Buxbaum, J. D. (2002) · Neurochemical Research · doi:10.1023/a:1020981510759 · Cited by 199

Estrogen Replacement Increases Spinophilin-immunoreactive Spine Number in the Prefrontal Cortex of Female Rhesus Monkeys

Tang, Y. C. (2003) · Cerebral Cortex · doi:10.1093/cercor/bhg121 · Cited by 195

Volume, neuron density and total neuron number in five subcortical regions in schizophrenia

Kreczmański, P., Heinsen, H., Mantua, V., Woltersdorf, F., Masson, T., Ulfig, N., Schmidt‐Kastner, R., Korr, H., Steinbusch, H. W. M., Hof, P. R., et al. (2007) · Brain · doi:10.1093/brain/awl386 · Cited by 196

Progressive degeneration of nonphosphorylated neurofilament protein-enriched pyramidal neurons predicts cognitive impairment in Alzheimer's disease: Stereologic analysis of prefrontal cortex area 9

Bussière, T., Giannakopoulos, P., Bouras, C., Perl, D. P., Morrison, J. H., & Hof, P. R. (2003) · Journal of Comparative Neurology · doi:10.1002/cne.10760 · Cited by 185

The presenilin-1 familial Alzheimer disease mutant P117L impairs neurogenesis in the hippocampus of adult mice

Wen, P. H., Hof, P. R., Chen, X., Gluck, K., Austin, G., Younkin, S. G., Younkin, L. H., DeGasperi, R., Sosa, M. A. G., Robakis, N. K. R. K., et al. (2004) · Experimental Neurology · doi:10.1016/j.expneurol.2004.04.002 · Cited by 193

Nonresonant powering of injectable nanoelectrodes enables wireless deep brain stimulation in freely moving mice

Kozielski, K., Jahanshahi, A., Gilbert, H. B., Yu, Y., Erin, Ö., Francisco, D., Alosaimi, F., Temel, Y., & Sitti, M. (2021) · Science Advances · doi:10.1126/sciadv.abc4189 · Cited by 183

The anterior cingulate cortex in autism: heterogeneity of qualitative and quantitative cytoarchitectonic features suggests possible subgroups

Simms, M. L., Kemper, T. L., Timbie, C. M., Bauman, M. L., & Blatt, G. J. (2009) · Acta Neuropathologica · doi:10.1007/s00401-009-0568-2 · Cited by 183

Lower motor neuron loss in multiple sclerosis and experimental autoimmune encephalomyelitis

Vogt, J., Paul, F., Aktas, O., Müller‐Wielsch, K., Dörr, J., Dörr, S., Bharathi, B. S., Glumm, R., Schmitz, C., Steinbusch, H., et al. (2009) · Annals of Neurology · doi:10.1002/ana.21719 · Cited by 157

Stereologic investigation of the posterior part of the hippocampus in schizophrenia

Schmitt, A., Steyskal, C., Bernstein, H., Schneider-Axmann, T., Parlapani, E., Schaeffer, E. L., Gattaz, W. F., Bogerts, B., Schmitz, C., & Falkai, P. (2008) · Acta Neuropathologica · doi:10.1007/s00401-008-0430-y · Cited by 167

Noradrenergic Innervation of the Dorsal Medial Prefrontal Cortex Modulates Hypothalamo-Pituitary-Adrenal Responses to Acute Emotional Stress

Radley, J. J., Williams, B., & Sawchenko, P. E. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.0552-08.2008 · Cited by 148

Nigrostriatal tau pathology in parkinsonism and Parkinson’s disease

Chu, Y., Hirst, W. D., Federoff, H. J., Harms, A. S., Stoessl, A. J., & Kordower, J. H. (2023) · Brain · doi:10.1093/brain/awad388 · Cited by 149

Preservation of hippocampal neuron numbers in aged rhesus monkeys

Keuker, J. I. H. (2002) · Neurobiology of Aging · doi:10.1016/s0197-4580(02)00062-3 · Cited by 142

Maternal immune activation during pregnancy increases limbic GABAA receptor immunoreactivity in the adult offspring: implications for schizophrenia

Nyffeler, M., Meyer, U., Yee, B. K., Feldon, J., & Knuesel, I. (2006) · Neuroscience · doi:10.1016/j.neuroscience.2006.07.029 · Cited by 139

Depression: reduced number of granule cells in the hippocampus of female, but not male, rats due to prenatal restraint stress

Schmitz, C., Rhodes, M. E., Bludau, M., Kaplan, S., Ong, P., Ueffing, I., Vehoff, J., Korr, H., & Frye, C. A. (2002) · Molecular Psychiatry · doi:10.1038/sj.mp.4001118 · Cited by 140

Early axonopathy preceding neurofibrillary tangles in mutant tau transgenic mice

Leroy, K., Bretteville, A., Schindowski, K., Gilissen, E., Authelet, M., De Decker, R., Yilmaz, Z., Buée, L., & Brion, J.-P. (2007) · The American Journal of Pathology · doi:10.2353/ajpath.2007.070345 · Cited by 135

Stereologic characterization and spatial distribution patterns of Betz cells in the human primary motor cortex

Rivara, C., Sherwood, C. C., Bouras, C., & Hof, P. R. (2003) · The Anatomical Record Part A Discoveries in Molecular Cellular and Evolutionary Biology · doi:10.1002/ar.a.10015 · Cited by 128

Cyclin D2 Is Critical for Intermediate Progenitor Cell Proliferation in the Embryonic Cortex

Glickstein, S. B., Monaghan, J. A., Koeller, H. B., Jones, T. K., & Ross, M. E. (2009) · The Journal of Neuroscience · doi:10.1523/jneurosci.2284-09.2009 · Cited by 124

Mice Lacking Dopamine D2 and D3 Receptors Exhibit Differential Activation of Prefrontal Cortical Neurons during Tasks Requiring Attention

Glickstein, S. B., DeSteno, D. A., Hof, P. R., & Schmauss, C. (2004) · Cerebral Cortex · doi:10.1093/cercor/bhh202 · Cited by 122

Stereologic analysis of neurofibrillary tangle formation in prefrontal cortex area 9 in aging and Alzheimer’s disease

Bussire, T., Gold, G., Kvari, E., Giannakopoulos, P., Bouras, C., Perl, D. P., Morrison, J. H., & Hof, P. R. (2003) · Neuroscience · doi:10.1016/s0306-4522(02)00942-9 · Cited by 122

Reduced GABAergic Inhibition in the Basolateral Amygdala and the Development of Anxiety-Like Behaviors after Mild Traumatic Brain Injury

Almeida-Suhett, C. P., Prager, E. M., Pidoplichko, V. I., Figueiredo, T. H., Marini, A. M., Li, Z., Eiden, L. E., & Braga, M. F. M. (2014) · PLoS ONE · doi:10.1371/journal.pone.0102627 · Cited by 123

Acute and separate modulation of motor and cognitive performance in parkinsonian rats by bilateral stimulation of the subthalamic nucleus

Temel, Y., Visser-Vandewalle, V. E. R. M., Aendekerk, B., Rutten, B. P. F., Tan, S. K. H., Scholtissen, B., Schmitz, C., Blokland, A., & Steinbusch, H. W. M. (2005) · Experimental Neurology · doi:10.1016/j.expneurol.2004.12.025 · Cited by 118

Mice Lacking Dopamine D2and D3Receptors Have Spatial Working Memory Deficits

Glickstein, S. B., Hof, P. R., & Schmauss, C. (2002) · Journal of Neuroscience · doi:10.1523/jneurosci.22-13-05619.2002 · Cited by 119

Extracorporeal shockwave application to the distal femur of rabbits diminishes the number of neurons immunoreactive for substance P in dorsal root ganglia L5

Hausdorf, J., Lemmens, M. A. M., Kaplan, S., Marangoz, C., Milz, S., Odacı, E., Korr, H., Schmitz, C., & Maier, M. (2008) · Brain Research · doi:10.1016/j.brainres.2008.02.013 · Cited by 119

Hyperoxic Reperfusion after Global Cerebral Ischemia Promotes Inflammation and Long-Term Hippocampal Neuronal Death

Hazelton, J. L., Balan, I. S., Elmer, G. I., Kristián, T., Rosenthal, R. E., Krause, G. S., Sanderson, T. H., & Fiskum, G. M. (2010) · Journal of Neurotrauma · doi:10.1089/neu.2009.1186 · Cited by 115

Cortical dopaminergic innervation among humans, chimpanzees, and macaque monkeys: A comparative study

Raghanti, M. A., Stimpson, C. D., Marcinkiewicz, J. L., Erwin, J. M., Hof, P. R., & Sherwood, C. C. (2008) · Neuroscience · doi:10.1016/j.neuroscience.2008.05.008 · Cited by 115

Overexpression of Wild Type But Not an FAD Mutant Presenilin-1 Promotes Neurogenesis in the Hippocampus of Adult Mice

Wen, P. H., Shao, X., Shao, Z., Hof, P. R., Wısnıewskı, T., Kelley, K. A., Friedrich, V. L., Ho, L., Pasinetti, G. M., Shioi, J., et al. (2002) · Neurobiology of Disease · doi:10.1006/nbdi.2002.0490 · Cited by 111

Comparison of maternal separation and early handling in terms of their neurobehavioral effects in aged rats

Lehmann, J. (2002) · Neurobiology of Aging · doi:10.1016/s0197-4580(01)00320-7 · Cited by 103

How to count cells: the advantages and disadvantages of the isotropic fractionator compared with stereology

Herculano‐Houzel, S., von Bartheld, C. S., Miller, D. J., & Kaas, J. H. (2015) · Cell and Tissue Research · doi:10.1007/s00441-015-2127-6 · Cited by 102

Cognitive impact of neuronal pathology in the entorhinal cortex and CA1 field in Alzheimer's disease

GUNTEN, A., KOVARI, E., BUSSIERE, T., RIVARA, C., GOLD, G., BOURAS, C., HOF, P., & GIANNAKOPOULOS, P. (2006) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2005.02.008 · Cited by 101

Myostatin inhibition slows muscle atrophy in rodent models of amyotrophic lateral sclerosis

Holzbaur, E. L. F., Howland, D., Weber, N., Wallace, K. E., She, Y., Kwak, S., Tchistiakova, L. A., Murphy, E. K., Hinson, J., Karim, R., et al. (2006) · Neurobiology of Disease · doi:10.1016/j.nbd.2006.05.009 · Cited by 104

Stereology, morphometry, and mapping: the whole is greater than the sum of its parts

Glaser, J. R., & Glaser, E. M. (2000) · Journal of Chemical Neuroanatomy · doi:10.1016/s0891-0618(00)00073-9 · Cited by 100

Antidepressant drug‐induced stimulation of mouse hippocampal neurogenesis is age‐dependent and altered by early life stress

Navailles, S., Hof, P. R., & Schmauss, C. (2008) · The Journal of Comparative Neurology · doi:10.1002/cne.21775 · Cited by 99

The use of design‐based stereology to evaluate volumes and numbers in the liver: a review with practical guidelines

Marcos, R., Monteiro, R. A. F., & Rocha, E. (2012) · Journal of Anatomy · doi:10.1111/j.1469-7580.2012.01475.x · Cited by 95

Prenatal PCBs disrupt early neuroendocrine development of the rat hypothalamus

Dickerson, S. M., Cunningham, S. L., & Gore, A. C. (2011) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2011.01.012 · Cited by 95

Involvement of precerebellar nuclei in multiple system atrophy

Braak, H., Rüb, U., & Tredici, K. D. (2003) · Neuropathology and Applied Neurobiology · doi:10.1046/j.1365-2990.2003.00432.x · Cited by 93

Stereologic analysis of estrogen receptor alpha (ERα) expression in rat hypothalamus and its regulation by aging and estrogen

Chakraborty, T. R., Hof, P. R., Ng, L., & Gore, A. C. (2003) · The Journal of Comparative Neurology · doi:10.1002/cne.10906 · Cited by 94

Extensive neuroprotection by choroid plexus transplants in excitotoxin lesioned monkeys

Emerich, D. F., Thanos, C. G., Goddard, M. B., Skinner, S. J. M., Geany, M. S., Bell, W. J., Bintz, B. E., Schneider, P. A., Chu, Y., Babu, R. S., et al. (2006) · Neurobiology of Disease · doi:10.1016/j.nbd.2006.04.014 · Cited by 93

Robust graft survival and normalized dopaminergic innervation do not obligate recovery in a P arkinson disease patient

Kordower, J. H., Goetz, C. G., Chu, Y., Halliday, G. M., Nicholson, D. A., Musial, T. F., Marmion, D. J., Stoessl, A. J., Sossi, V., Freeman, T. B., et al. (2016) · Annals of Neurology · doi:10.1002/ana.24820 · Cited by 92

Selective cortical interneuron and GABA deficits in cyclin D2-null mice

Glickstein, S. B., Moore, H., Slowinska, B., Racchumi, J., Suh, M., Chuhma, N., & Ross, M. E. (2007) · Development · doi:10.1242/dev.008524 · Cited by 89

Caloric restriction attenuates age-related changes of DNA methyltransferase 3a in mouse hippocampus

Chouliaras, L., van den Hove, D. L. A., Kenis, G., Dela Cruz, J., Lemmens, M. A. M., van Os, J., Steinbusch, H. W. M., Schmitz, C., & Rutten, B. P. F. (2011) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2010.11.016 · Cited by 89

GABAergic interneuronal loss and reduced inhibitory synaptic transmission in the hippocampal CA1 region after mild traumatic brain injury

Almeida-Suhett, C. P., Prager, E., Pidoplichko, V. I., Figueiredo, T. H., Marini, A., Li, Z., Eiden, L., & Braga, M. F. (2015) · Experimental Neurology · doi:10.1016/j.expneurol.2015.07.028 · Cited by 78

Selective Deletion of Cochlear Hair Cells Causes Rapid Age-Dependent Changes in Spiral Ganglion and Cochlear Nucleus Neurons

Tong, L., Strong, M. K., Kaur, T., Juiz, J. M., Oesterle, E. C., Hume, C. R., Warchol, M. E., Palmiter, R. D., & Rubel, E. W. (2015) · Journal of Neuroscience · doi:10.1523/jneurosci.2179-14.2015 · Cited by 89

Long-term post-mortem studies following neurturin gene therapy in patients with advanced Parkinson’s disease

Chu, Y., Bartus, R. T., Manfredsson, F. P., Olanow, C. W., & Kordower, J. H. (2020) · Brain · doi:10.1093/brain/awaa020 · Cited by 88

Behavioral and neurobiological effects of prenatal stress exposure in male and female APPswe/PS1dE9 mice

Sierksma, A. S. R., Prickaerts, J., Chouliaras, L., Rostamian, S., Delbroek, L., Rutten, B. P. F., Steinbusch, H. W. M., & van den Hove, D. (2012) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2012.05.012 · Cited by 88

Stereologic Analysis of Microvascular Morphology in the Elderly

Bouras, C., Kövari, E., Herrmann, F. R., Rivara, C., Bailey, T. L., von Gunten, A., Hof, P. R., & Giannakopoulos, P. (2006) · Journal of Neuropathology & Experimental Neurology · doi:10.1097/01.jnen.0000203077.53080.2c · Cited by 85

Stereologic Evidence for Persistence of Viable Neurons in Layer II of the Entorhinal Cortex and the CA1 Field in Alzheimer Disease

Hof, P. R., Bussière, T., Gold, G., Kövari, E., Giannakopoulos, P., Bouras, C., Perl, D. P., & Morrison, J. H. (2003) · Journal of Neuropathology & Experimental Neurology · doi:10.1093/jnen/62.1.55 · Cited by 85

Immediate-early gene expression in structures outside the basal ganglia is associated to l-DOPA-induced dyskinesia

Bastide, M. F., Doveró, S., Charron, G., Porras, G., Gross, C. E., Fernagut, P., & Bézard, E. (2013) · Neurobiology of Disease · doi:10.1016/j.nbd.2013.09.020 · Cited by 82

Differences in Cortical Serotonergic Innervation among Humans, Chimpanzees, and Macaque Monkeys: A Comparative Study

Raghanti, M. A., Stimpson, C. D., Marcinkiewicz, J. L., Erwin, J. M., Hof, P. R., & Sherwood, C. C. (2007) · Cerebral Cortex · doi:10.1093/cercor/bhm089 · Cited by 81

Accelerated Human Mutant Tau Aggregation by Knocking Out Murine Tau in a Transgenic Mouse Model

Ando, K., Leroy, K., Héraud, C., Yilmaz, Z., Authelet, M., Suain, V., Decker, R. D., & Brion, J. (2011) · American Journal Of Pathology · doi:10.1016/j.ajpath.2010.10.034 · Cited by 80

Synaptic Organization of Perisomatic GABAergic Inputs onto the Principal Cells of the Mouse Basolateral Amygdala

Vereczki, V., Veres, J. M., Müller, K., Nagy, G. A., Rácz, B., Barsy, B., & Hájos, N. (2016) · Frontiers in Neuroanatomy · doi:10.3389/fnana.2016.00020 · Cited by 79

High-fat diet worsens the impact of aging on microglial function and morphology in a region-specific manner

Spencer, S. J., Basri, B., Sominsky, L., Soch, A., Ayala, M. T., Reineck, P., Gibson, B. C., & Barrientos, R. M. (2018) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2018.10.018 · Cited by 80

The aging brain: Accumulation of DNA damage or neuron loss?

Rutten, B. P. F., Schmitz, C., Gerlach, O. H. H., Oyen, H. M., de Mesquita, E. B., Steinbusch, H. W. M., & Korr, H. (2005) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2005.10.019 · Cited by 81

Myths and truths about the cellular composition of the human brain: A review of influential concepts

von Bartheld, C. S. (2017) · Journal of Chemical Neuroanatomy · doi:10.1016/j.jchemneu.2017.08.004 · Cited by 87

Ecomorphology of eye shape and retinal topography in waterfowl (Aves: Anseriformes: Anatidae) with different foraging modes

Lisney, T. J., Stecyk, K., Kolominsky, J., Schmidt, B. K., Corfield, J. R., Iwaniuk, A. N., & WYLIE, D. R. W. (2013) · Journal of Comparative Physiology A · doi:10.1007/s00359-013-0802-1 · Cited by 76

Truncated tau expression levels determine life span of a rat model of tauopathy without causing neuronal loss or correlating with terminal neurofibrillary tangle load

Koson, P., Žilka, N., Kováč, A., Kováčech, B., Korenova, M., Filipčík, P., & Novák, M. (2008) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2008.06329.x · Cited by 75

Abnormal alpha-synuclein reduces nigral voltage-dependent anion channel 1 in sporadic and experimental Parkinson's disease

Chu, Y., Goldman, J. G., Kelly, L. P., He, Y., Waliczek, T., & Kordower, J. H. (2014) · Neurobiology of Disease · doi:10.1016/j.nbd.2014.05.003 · Cited by 71

Compacted DNA Nanoparticle Gene Transfer of GDNF to the Rat Striatum Enhances the Survival of Grafted Fetal Dopamine Neurons

Yurek, D. M., Fletcher‐Turner, A., Kowalczyk, T. H., Padegimas, L., & Cooper, M. J. (2009) · Cell Transplantation · doi:10.3727/096368909x12483162196881 · Cited by 74

Selective striatal neuron loss and alterations in behavior correlate with impaired striatal function in Huntington's disease transgenic rats

Kántor, O., Temel, Y., Holzmann, C., Raber, K. A., Nguyen, H. P., Cao, C., Ozen, H., Rutten, B. P. F., Visser-Vandewalle, V. E. R. M., Steinbusch, H. W. M., et al. (2006) · Neurobiology of Disease · doi:10.1016/j.nbd.2005.12.014 · Cited by 75

The GluK1 (GluR5) Kainate/α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid Receptor Antagonist LY293558 Reduces Soman-Induced Seizures and Neuropathology

Figueiredo, T. H., Qashu, F. M., Apland, J. P., Aroniadou‐Anderjaska, V., de Souza, A. P., & Braga, M. F. M. (2010) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.110.171835 · Cited by 69

Scaling of Inhibitory Interneurons in Areas V1 and V2 of Anthropoid Primates as Revealed by Calcium-Binding Protein Immunohistochemistry

Sherwood, C. C., Raghanti, M. A., Stimpson, C. D., Bonar, C. J., de Sousa, A. A., Preuss, T. M., & Hof, P. R. (2006) · Brain Behavior and Evolution · doi:10.1159/000096986 · Cited by 68

Effects of polychlorinated biphenyls on estrogen receptor-beta expression in the anteroventral periventricular nucleus.

Salama, J., Chakraborty, T. R., Ng, L., & Gore, A. C. (2003) · Environmental Health Perspectives · doi:10.1289/ehp.6126 · Cited by 69

Comparison of eye morphology and retinal topography in two species of new world vultures (Aves: Cathartidae)

Lisney, T. J., Stecyk, K., Kolominsky, J., Graves, G. R., WYLIE, D. R. W., & Iwaniuk, A. N. (2013) · The Anatomical Record · doi:10.1002/ar.22815 · Cited by 70

The Limitations of Diazepam as a Treatment for Nerve Agent–Induced Seizures and Neuropathology in Rats: Comparison with UBP302

Apland, J. P., Aroniadou‐Anderjaska, V., Figueiredo, T. H., Rossetti, F., Miller, S. L., & Braga, M. F. M. (2014) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.114.217299 · Cited by 67

Age-Related Changes in Estrogen Receptor β in Rat Hypothalamus: A Quantitative Analysis

Chakraborty, T. R., Ng, L., & Gore, A. C. (2003) · Endocrinology · doi:10.1210/en.2003-0052 · Cited by 66

Spinocerebellar ataxia type 3 (Machado-Joseph disease): severe destruction of the lateral reticular nucleus

Rüb, U. (2002) · Brain · doi:10.1093/brain/awf208 · Cited by 66

Damage to the reticulotegmental nucleus of the pons in spinocerebellar ataxia type 1, 2, and 3

Rüb, U., Bürk, K., Schöls, L., Brunt, E., de Vos, R., Díaz, G. O., Gierga, K., Ghebremedhin, E., Schultz, C., Turco, D. D., et al. (2004) · Neurology · doi:10.1212/01.wnl.0000140498.24112.8c · Cited by 58

Cholinergic innervation of the frontal cortex: Differences among humans, chimpanzees, and macaque monkeys

Raghanti, M. A., Stimpson, C. D., Marcinkiewicz, J. L., ERWIN, J. M., Hof, P. R., & Sherwood, C. C. (2007) · The Journal of Comparative Neurology · doi:10.1002/cne.21546 · Cited by 62

Impact of perinatal asphyxia on the GABAergic and locomotor system

van de Berg, W. D. J., Kwaijtaal, M., de Louw, A. J. A., Lissone, N. P. A., Schmitz, C., Faull, R. L. M., Blokland, A., Blanco, C. E., & Steinbusch, H. W. M. (2003) · Neuroscience · doi:10.1016/s0306-4522(02)00787-x · Cited by 62

Total Number and Ratio of GABAergic Neuron Types in the Mouse Lateral and Basal Amygdala

Vereczki, V., Müller, K., Krizsán, É., Máté, Z., Fekete, Z., Rovira-Esteban, L., Veres, J. M., Erdélyi, F., & Hájos, N. (2021) · Journal of Neuroscience · doi:10.1523/jneurosci.2700-20.2021 · Cited by 65

Practical approaches to stereology in the setting of aging- and disease-related brain banks

Perl, D. P., Good, P. F., Bussière, T., Morrison, J. H., ERWIN, J. M., & Hof, P. R. (2000) · Journal of Chemical Neuroanatomy · doi:10.1016/s0891-0618(00)00077-6 · Cited by 61

Changes in androgen receptor, estrogen receptor alpha, and sexual behavior with aging and testosterone in male rats

Wu, D., & Gore, A. C. (2010) · Hormones and Behavior · doi:10.1016/j.yhbeh.2010.03.001 · Cited by 61

The revolution of counting “tops”: Two decades of the disector principle in morphological research

Geuna, S. (2005) · Microscopy Research and Technique · doi:10.1002/jemt.20167 · Cited by 60

Pathological alterations in GABAergic interneurons and reduced tonic inhibition in the basolateral amygdala during epileptogenesis

Fritsch, B., Qashu, F. M., Figueiredo, T. H., Aroniadou‐Anderjaska, V., Rogawski, M. A., & Braga, M. F. M. (2009) · Neuroscience · doi:10.1016/j.neuroscience.2009.06.034 · Cited by 60

The recovery of acetylcholinesterase activity and the progression of neuropathological and pathophysiological alterations in the rat basolateral amygdala after soman-induced status epilepticus: Relation to anxiety-like behavior

Prager, E. M., Aroniadou‐Anderjaska, V., Almeida-Suhett, C. P., Figueiredo, T. H., Apland, J. P., Rossetti, F., Olsen, C. H., & Braga, M. F. M. (2014) · Neuropharmacology · doi:10.1016/j.neuropharm.2014.01.035 · Cited by 58

Running exercise protects oligodendrocytes in the medial prefrontal cortex in chronic unpredictable stress rat model

Luo, Y., Xiao, Q., Wang, J., Jiang, L. H., Hu, M., Jiang, Y., Tang, J., Liang, X., Qi, Y., Dou, X., et al. (2019) · Translational Psychiatry · doi:10.1038/s41398-019-0662-8 · Cited by 57

Dispersible amyloid β-protein oligomers, protofibrils, and fibrils represent diffusible but not soluble aggregates: their role in neurodegeneration in amyloid precursor protein (APP) transgenic mice

Upadhaya, A. R., Capetillo‐Zarate, E., Kosterin, I., Abramowski, D., Kumar, S., Yamaguchi, H., Walter, J., Fändrich, M., Staufenbiel, M., & Thal, D. R. (2012) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2011.12.032 · Cited by 54

Cell Number and Neuropil Alterations in Subregions of the Anterior Hippocampus in a Female Monkey Model of Depression

Willard, S. L., Riddle, D. R., Forbes, M. E., & Shively, C. A. (2013) · Biological Psychiatry · doi:10.1016/j.biopsych.2013.03.013 · Cited by 56

Update on stereology for light microscopy

Geuna, S., & Herrera‐Rincon, C. (2015) · Cell and Tissue Research · doi:10.1007/s00441-015-2143-6 · Cited by 54

The Tangle of Science

Cartwright, N. D., Hardie, J., Montuschi, E., Soleiman, M., & Thresher, A. C. (2022) · doi:10.1093/oso/9780198866343.001.0001 · Cited by 58

Acetylcholinesterase inhibition in the basolateral amygdala plays a key role in the induction of status epilepticus after soman exposure

Prager, E. M., Aroniadou‐Anderjaska, V., Almeida-Suhett, C. P., Figueiredo, T. H., Apland, J. P., & Braga, M. F. M. (2013) · NeuroToxicology · doi:10.1016/j.neuro.2013.06.006 · Cited by 52

Unbiased stereological estimation of the total number of neurons in the subdivisions of the rat hippocampus using the optical fractionator

West, M. J., Slomianka, L., & Gundersen, H. J. G. (1991) · The Anatomical Record · doi:10.1002/ar.1092310411 · Cited by 2,994

Design-based stereological methods for counting neurons

West, M. J. (2002) · Progress in brain research · doi:10.1016/s0079-6123(02)35006-4 · Cited by 122

Comparison of empirical and estimated efficiency in neuron counting by the fractionator method and in volume measurement by Cavalieri’s method

Guntinas‐Lichius, O., & Neiss, W. F. (1996) · Image Analysis & Stereology · Cited by 3

Application of stereology to the central nervous system: estimation of numerical densities of neurons and synapses or neuron number

Fukui, Y., & Bedi, K. S. (2000) · Congenital Anomalies · doi:10.1111/j.1741-4520.2000.tb00902.x · Cited by 2

Isotropic Fractionator: A Simple, Rapid Method for the Quantification of Total Cell and Neuron Numbers in the Brain

Herculano-Houzel, S., & Lent, R. (2005) · The Journal of Neuroscience · doi:10.1523/jneurosci.4526-04.2005 · Cited by 551