The DOI matches its Crossref record; 56 of the 59 references it cites were found in a registry or an index.
Prenatal Substance Exposure
Abstract
Attention and impulsivity of prenatally substance-exposed 6 year olds were assessed as part of a longitudinal study. Most of the women were light to moderate users of alcohol and marijuana who decreased their use after the first trimester of pregnancy. Tobacco was used by a majority of women and did not change during pregnancy. The women, recruited from a prenatal clinic, were of lower socio-economic status, and over half were African American. Attention and impulsivity were assessed using a Continuous Performance Task. Second and third trimester tobacco exposure and first trimester cocaine use predicted increased omission errors. Second trimester marijuana use predicted more commission errors and fewer omission errors. There were no significant effects of prenatal alcohol exposure. Lower Stanford-Binet Intelligence Scale composite scores, male gender, and an adult male in the household also predicted more errors of commission. Lower SBIS composite scores, younger child age, maternal work/ school status, and higher maternal hostility scores predicted more omission errors. These findings indicate that prenatal substance use has an effect on attentional processes.
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“Maternal smoking during pregnancy has been linked to low birthweight, admission to neonatal intensive care units, increased risk for sudden infant death syndrome,2, 3, 6 and long-term adverse neurobehavioral outcomes in offspring including attention deficits, hyperactivity, conduct disorder, and substance/nicotine use.7–10.”
From Maternal Smoking during Pregnancy and Newborn Neurobehavior: Effects at 10 to 27 Days (2009) · cites this paper as [9]
Citations
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Items 301–302 of 302
Buck, J. M., Melnick, M., & Stitzel, J. A. (2026) · Genes · doi:10.3390/genes17020128
Mendes, P. F. S., Baia-da-Silva, D. C., dos Santos, V. R. N., Bittencourt, L. O., Pantoja, L. V. P. D. S., Fernandes, L. M. P., Burbano, R. M. R., Maia, C. D. S. F., & Lima, R. R. (2026) · Toxicological Sciences · doi:10.1093/toxsci/kfag123
Metadata
- Authors
- Leech, S. L., Richardson, G. A., Goldschmidt, L., & Day, N. L.
- Affiliations
- University of Pittsburgh Medical Center (US)
- University of Pittsburgh (US)
- Corresponding author
- Richardson, G.A
- Venue
- Neurotoxicology and Teratology
- Publisher
- Elsevier BV
- Published
- 1999-03
- Volume
- 21
- Issue
- 2
- Pages
- 109-118
- ISSN
- 0892-0362 (ISSN-L)
- OpenAlex
- W138330660
- Cited by
- 302
- References
- 59
- Citations by year
- 2026: 4 · 2025: 9 · 2024: 8 · 2023: 11 · 2022: 9 · 2021: 7 · 2020: 10 · 2019: 9 · 2018: 3 · 2017: 5 · 2016: 9 · 2015: 8 · 2014: 17 · 2013: 9 · 2012: 11
- FWCI
- 14.68
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Neurotoxicology and Teratology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institute on Alcohol Abuse and Alcoholism (AA06666, R01AA006666)
- National Institute on Drug Abuse (R01DA003874, DA 03874)
- Topics
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Prenatal Substance Exposure Effects
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Maternal Mental Health During Pregnancy and Postpartum
- Keywords
- prenatal drug exposure, prenatal alcohol exposure, prenatal cannabis exposure, prenatal tobacco exposure, prenatal cocaine exposure, attention, impulsivity, omission errors, commission errors, continuous performance test, child intelligence, maternal hostility, socioeconomic status, African American mothers
- MeSH terms
- Adult, Ethanol, Attention, Black or African American, Cannabis, Central Nervous System Depressants, Child, Female, Hostility, Humans, Impulsive Behavior, Intelligence Tests, Male, Pregnancy, Prenatal Exposure Delayed Effects, Psychomotor Performance, Sex Characteristics, Smoking, Social Class, White People
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