The DOI matches its Crossref record; 20 of the 20 references it cites were found in a registry or an index.
Pulse pressure and heart rate
Abstract
In the present study, the roles of heart rate (HR) and pulse pressure (PP) on cancer mortality, after taking into account physical activity, cigarette smoking, alcohol consumption and other confounding factors or underlying disease, were examined in men. The study included 125,513 men aged 20 to 95 years who had a health check-up at the IPC Center between 1978 and 1988. HR and PP were classified into three groups: < 60, 60-80, > 80 bpm for HR and < 50, 51-64, > or = 65 mmHg for PP. Adjusted risk ratios related to the increment from one class of HR or PP to the next for all cancer mortality were 1.4 (1.2-1.5) and 1.3 (1.1-1.4), respectively. This relationship was independent of several known risk and confounding factors, especially cigarette smoking and physical activity, and could not be explained by the presence of underlying disease.
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“Similarly, more chronic elevations in SNS activity can raise blood pressure and heart rate that promotes atherosclerosis, and appears to be independently associated with cancer mortality.37”
From Socio‐economic differentials in peripheral biology: Cumulative allostatic load (2010) · cites this paper as [37]
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Cites
Heart rate and cardiovascular mortality: The Framingham study
Kannel, W. B., Kannel, C., Paffenbarger, R. S., & Cupples, L. A. (1987) · American Heart Journal · doi:10.1016/0002-8703(87)90666-1 · Cited by 1,292
Bénétos, A., Safar, M. E., Rudnichi, A., Smulyan, H., Richard, J. L., Ducimetière, P., & Guize, L. (1997) · Hypertension · doi:10.1161/01.hyp.30.6.1410 · Cited by 1,033
Self-citationInfluence of heart rate on mortality among persons with hypertension: The Framingham Study
Gillman, M. W., Kannel, W. B., Belanger, A. J., & D’Agostino, R. B. (1993) · American Heart Journal · doi:10.1016/0002-8703(93)90128-v · Cited by 622
Increased Pulse Pressure and Risk of Heart Failure in the Elderly
Chae, C. U. (1999) · JAMA · doi:10.1001/jama.281.7.634 · Cited by 575
Mitchell, G. F., Moyé, L. A., Braunwald, E., Rouleau, J. L., Bernstein, V., Geltman, E. M., Flaker, G. C., Pfeffer, M. A., & for the SAVE Investigators (1997) · Circulation · doi:10.1161/01.cir.96.12.4254 · Cited by 527
Heart rate and the cardiovascular risk
Palatini, P., & Julius, S. (1997) · Journal of Hypertension · doi:10.1097/00004872-199715010-00001 · Cited by 508
Influence of Heart Rate on Mortality in a French Population: Role of Age, Gender, and Blood Pressure
Benetos, A., Rudnichi, A., Thomas, F., Safar, M., & Guize, L. (1999) · Hypertension · doi:10.1161/01.hyp.33.1.44 · Cited by 356
Self-citationPARKINSON, T. (1947) · PubMed · Cited by 199
The relationship between resting heart rate and all-cause, cardiovascular and cancer mortality
Mensink, G., & Hoffmeister, H. M. (1997) · European Heart Journal · doi:10.1093/oxfordjournals.eurheartj.a015465 · Cited by 179
HIGH BLOOD-PRESSURE: A RISK FACTOR FOR CANCER MORTALITY ?
Dyer, A., Berkson, D. M., Stamler, J., Lindberg, H. A., & Stevens, E. (1975) · The Lancet · doi:10.1016/s0140-6736(75)91826-7 · Cited by 138
Research works printed but not linked: 2
- Goldbourt, 1986, Elevated systolic blood pressure as a predictor of long-term cancer mortality, J Natl Cancer Inst, 77, 63
- Gann, 1995, Heart rate and prostate cancer mortality, Cancer Epidemiol Biomarkers Prev, 4, 611
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Seeman, T., Epel, E., Gruenewald, T., Karlamangla, A., & McEwen, B. S. (2010) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2009.05341.x · Cited by 579
Allostatic load as a predictor of functional decline
Karlamangla, A. S., Singer, B. H., McEwen, B. S., Rowe, J. W., & Seeman, T. E. (2002) · Journal of Clinical Epidemiology · doi:10.1016/s0895-4356(02)00399-2 · Cited by 483
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Anker, M. S., Ebner, N., Hildebrandt, B., Springer, J., Sinn, M., Riess, H. B., Anker, S. D., Landmesser, U., Haverkamp, W., & von Haehling, S. (2016) · European Journal of Heart Failure · doi:10.1002/ejhf.670 · Cited by 105
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Heart Rate and Risk of Cancer Death in Healthy Men
Jouven, X., Escolano, S., Celermajer, D. S., Empana, J. P., Bingham, A., Hermine, O., Desnos, M., Perier, M., Marijon, É., & Ducimetière, P. (2011) · PLoS ONE · doi:10.1371/journal.pone.0021310 · Cited by 52
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Vukadinović, A. N., Vukadinović, D., BORER, J. S., Cowie, M., Michel Komajda, N., Lainščak, M., Swedberg, K. B., & Böhm, M. (2017) · European Journal of Heart Failure · doi:10.1002/ejhf.902 · Cited by 51
Resting heart rate, mortality and future coronary heart disease in the elderly: the 3C study
Legeai, C., Jouven, X., Tafflet, M., Jf, D., Helmer, C., Ritchie, K. A., Amouyel, P., Tzourio, C., Ducimetière, P., & Empana, J. P. (2011) · European Journal of Cardiovascular Prevention & Rehabilitation · doi:10.1177/1741826710389365 · Cited by 44
Bae, C., Kang, Y. G., Piao, M.-H., Cho, B., Cho, K., Park, Y. K., Yu, B.-Y., Lee, S.-W., Kim, M. J., Lee, S., et al. (2013) · Maturitas · doi:10.1016/j.maturitas.2013.04.008 · Cited by 29
Evidence for a gene influencing heart rate on chromosome 4 among hypertensives
Wilk, J. B., Myers, R. H., Zhang, Y., Lewis, C. E., Atwood, L. D., Hopkins, P. N., & Ellison, R. C. (2002) · Human Genetics · doi:10.1007/s00439-002-0780-9 · Cited by 25
Resting Heart Rate as a Predictor of Cancer Mortality: A Systematic Review and Meta-Analysis
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Subclinical cardiac damage in cancer patients before chemotherapy
Fabiani, I., Panichella, G., Aimo, A., Grigoratos, C., Vergaro, G., Pugliese, N. R., Taddei, S., Cardinale, D. M., Passino, C., Emdin, M., et al. (2021) · Heart Failure Reviews · doi:10.1007/s10741-021-10151-4 · Cited by 21
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Office and out of office heart rate measurements: which clinical value?
Palatini, P., Parati, G., & Julius, S. (2008) · Journal of Hypertension · doi:10.1097/hjh.0b013e32830b5f60 · Cited by 5
Han, C., Zhang, M., Luo, X., Wang, C., Zhou, J., Zhang, L., Ren, Y., Wang, B., Yang, X., Zhang, H., et al. (2016) · Journal of Public Health · doi:10.1007/s10389-016-0760-5 · Cited by 3
Cho, W., Kim, H. S., Lee, D. H., Park, D., Lee, M. K., Yang, S. Y., Min, B. S., Courneya, K. S., Meyerhardt, J. A., Giovannucci, E. L., et al. (2025) · Cancer Epidemiology Biomarkers & Prevention · doi:10.1158/1055-9965.epi-25-0704 · Cited by 1
Metadata
- Authors
- Thomas, F., Guize, L., Bean, K., & Benetos, A.
- Venue
- Journal of Clinical Epidemiology
- Publisher
- Elsevier BV
- Published
- 2001-07
- Volume
- 54
- Issue
- 7
- Pages
- 735-740
- ISSN
- 0895-4356 (ISSN-L)
- OpenAlex
- W1999441208
- Cited by
- 21
- References
- 20
- Citations by year
- 2025: 1 · 2021: 3 · 2018: 1 · 2017: 2 · 2016: 4 · 2014: 1 · 2013: 1
- FWCI
- 0.73
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Clinical Epidemiology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Risk Factors
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Disease Prevention
- Health Sciences › Medicine › Oncology › Cancer Risks and Factors
- Keywords
- pulse pressure, heart rate, cancer mortality, cardiovascular risk factors, men, cigarette smoking, physical activity, alcohol consumption, underlying disease
- MeSH terms
- Adult, Aged, France, Heart Rate, Humans, Male, Middle Aged, Neoplasms, Pulse, Risk Factors, Smoking, Exercise, Confounding Factors, Epidemiologic
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