Homer Binds a Novel Proline-Rich Motif and Links Group 1 Metabotropic Glutamate Receptors with IP3 Receptors

PHARMACOLOGY AND FUNCTIONS OF METABOTROPIC GLUTAMATE RECEPTORS

Conn, P. J., & Pin, J. (1997) · The Annual Review of Pharmacology and Toxicology · doi:10.1146/annurev.pharmtox.37.1.205 · Cited by 3,083

Sequence and expression of a metabotropic glutamate receptor

Masu, M., Tanabe, Y., Tsuchida, K., Shigemoto, R., & Nakanishi, S. (1991) · Nature · doi:10.1038/349760a0 · Cited by 1,216

Homer: a protein that selectively binds metabotropic glutamate receptors

Brakeman, P., Lanahan, A. A., O’Brien, R., Roche, K. W., Barnes, C. A., Huganir, R. L., & Worley, P. F. (1997) · Nature · doi:10.1038/386284a0 · Cited by 1,115

Structural basis for the binding of proline-rich peptides to SH3 domains

Yu, H., Chen, J., Feng, S., Dalgarno, D. C., Brauer, A. W., & Schrelber, S. L. (1994) · Cell · doi:10.1016/0092-8674(94)90367-0 · Cited by 1,003

A family of metabotropic glutamate receptors

Tanabe, Y., Masu, M., Ishii, T., Shigemoto, R., & Nakanishi, S. (1992) · Neuron · doi:10.1016/0896-6273(92)90118-w · Cited by 940

The role of excitatory amino acids in behavioral sensitization to psychomotor stimulants

Wolf, M. E. (1998) · Progress in Neurobiology · doi:10.1016/s0301-0082(97)00090-7 · Cited by 934

The metabotropic glutamate receptor (mGluRlα) is concentrated at perisynaptic membrane of neuronal subpopulations as detected by immunogold reaction

Baude, A., Nusser, Z., Roberts, J. D. B., Mulvihill, E., Jeffrey Mcllhinney, R. A., & Somogyi, P. (1993) · Neuron · doi:10.1016/0896-6273(93)90086-7 · Cited by 927

A family of metabotropic glutamate receptors

Tanabe, Y. (1992) · Medical Entomology and Zoology · doi:10.11501/3061113 · Cited by 879

Wiskott–Aldrich Syndrome Protein, a Novel Effector for the GTPase CDC42Hs, Is Implicated in Actin Polymerization

Symons, M. H., Derry, J. M. J., Karlak, B., Jiang, S., Lemahieu, V., McCormick, F. P., Francke, U., & Abo, A. (1996) · Cell · doi:10.1016/s0092-8674(00)81050-8 · Cited by 830

Molecular characterization of a novel metabotropic glutamate receptor mGluR5 coupled to inositol phosphate/Ca2+ signal transduction.

Abe, T., Sugihara, H., Nawa, H., Shigemoto, R., Mizuno, N., & Nakanishi, S. (1992) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)42219-3 · Cited by 815

Enhancing Oligodendrocyte Myelination Rescues Synaptic Loss and Improves Functional Recovery after Chronic Hypoxia

Wang, F., Yang, Y., Yang, N., Chen, X., Huang, N.-X., Zhang, J., Wu, Y., Liu, Z., Gao, X., Li, T., et al. (2018) · Neuron · doi:10.1016/j.neuron.2018.07.017 · Cited by 208

G protein-coupled receptor signalling and cross-talk

Hur, E., & Kim, K. (2002) · Cellular Signalling · doi:10.1016/s0898-6568(01)00258-3 · Cited by 197

AAV-mediated hippocampal expression of short and long Homer 1 proteins differentially affect cognition and seizure activity in adult rats

Klugmann, M., Symes, C. W., Leichtlein, C. B., Klaussner, B. K., Dunning, J., Fong, D. M., Young, D., & During, M. J. (2004) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2004.10.002 · Cited by 198

IRBIT, a Novel Inositol 1,4,5-Trisphosphate (IP3) Receptor-binding Protein, Is Released from the IP3 Receptor upon IP3 Binding to the Receptor

Ando, H., Mizutani, A., Matsuura, T., & Mikoshiba, K. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m210119200 · Cited by 195

Using glutamate homeostasis as a target for treating addictive disorders

Reissner, K. J., & Kalivas, P. W. (2010) · Behavioural Pharmacology · doi:10.1097/fbp.0b013e32833d41b2 · Cited by 201

Homer Proteins Regulate Coupling of Group I Metabotropic Glutamate Receptors to N-Type Calcium and M-Type Potassium Channels

Kammermeier, P. J., Xiao, B., Tu, J. C., Worley, P. F., & Ikeda, S. R. (2000) · Journal of Neuroscience · doi:10.1523/jneurosci.20-19-07238.2000 · Cited by 195

The role of the endoplasmic reticulum Ca2+ store in the plasticity of central neurons

Bardo, S. J., Cavazzini, M., & Emptage, N. J. (2006) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2005.12.008 · Cited by 188

Sex Differences in Molecular Signaling at Inhibitory Synapses in the Hippocampus

Tabatadze, N., Huang, G., May, R. M., Jain, A., & Woolley, C. S. (2015) · Journal of Neuroscience · doi:10.1523/jneurosci.1067-15.2015 · Cited by 191

Determination of absolute protein numbers in single synapses by a GFP-based calibration technique

Sugiyama, Y., Kawabata, I., Sobue, K., & Okabe, S. (2005) · Nature Methods · doi:10.1038/nmeth783 · Cited by 189

Structure and Function of IP 3 ReceptorsPreprint

Prole, D. L., & Taylor, C. W. (2019) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a035063 · Cited by 194

Spine growth in the anterior cingulate cortex is necessary for the consolidation of contextual fear memory

Vetere, G., Restivo, L., Cole, C. J., Ross, P. J., Ammassari‐Teule, M., Josselyn, S. A., & Frankland, P. W. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1016275108 · Cited by 183

Vitamin D and Depression: Cellular and Regulatory Mechanisms

Berridge, M. J. (2017) · Pharmacological Reviews · doi:10.1124/pr.116.013227 · Cited by 194

BANK regulates BCR‐induced calcium mobilization by promoting tyrosine phosphorylation of IP3 receptor

Yokoyama, K., Su, I.-H., Tezuka, T., Yasuda, T., Mikoshiba, K., Tarakhovsky, A., & Yamamoto, T. S. (2002) · The EMBO Journal · doi:10.1093/emboj/21.1.83 · Cited by 183

Subcellular distribution of the inositol 1,4,5‐trisphosphate receptors: functional relevance and molecular determinants

Vermassen, E., Parys, J. B., & Mauger, J. (2004) · Biology of the Cell · doi:10.1016/j.biolcel.2003.11.004 · Cited by 185

Gene profiling links SCA1 pathophysiology to glutamate signaling in Purkinje cells of transgenic mice

Serra, H. G., Byam, C. E., Lande, J. D., Tousey, S. K., Zoghbi, H. Y., & Orr, H. T. (2004) · Human Molecular Genetics · doi:10.1093/hmg/ddh268 · Cited by 176

Receptor Activation and Homer Differentially Control the Lateral Mobility of Metabotropic Glutamate Receptor 5 in the Neuronal Membrane

Sergé, A., Fourgeaud, L., Hémar, A., & Choquet, D. (2002) · Journal of Neuroscience · doi:10.1523/jneurosci.22-10-03910.2002 · Cited by 175

Homer proteins: implications for neuropsychiatric disorders

Szumlinski, K. K., Kalivas, P. W., & Worley, P. F. (2006) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2006.05.002 · Cited by 174

Inositol 1,4,5-Trisphosphate (IP3)-Mediated Ca2+Release Evoked by Metabotropic Agonists and Backpropagating Action Potentials in Hippocampal CA1 Pyramidal Neurons

Nakamura, T., Nakamura, K. M., Lasser‐Ross, N., Barbara, J., Sandler, V. M., & Ross, W. N. (2000) · Journal of Neuroscience · doi:10.1523/jneurosci.20-22-08365.2000 · Cited by 173

Role of PDZ Proteins in Regulating Trafficking, Signaling, and Function of GPCRs: Means, Motif, and Opportunity

Romero, G. G., von Zastrow, M., & Friedman, P. A. (2011) · Advances in pharmacology · doi:10.1016/b978-0-12-385952-5.00003-8 · Cited by 176

G-protein-independent signaling mediated by metabotropic glutamate receptors

Heuss, C., Scanziani, M., Gähwiler, B. H., & Gerber, U. R. (1999) · Nature Neuroscience · doi:10.1038/15996 · Cited by 171

A Key Role for Diacylglycerol Lipase-α in Metabotropic Glutamate Receptor-Dependent Endocannabinoid Mobilization

Jung, K., Astarita, G., Zhu, C., Wallace, M., Mackie, K., & Piomelli, D. (2007) · Molecular Pharmacology · doi:10.1124/mol.107.037796 · Cited by 170

Mechanisms of homeostatic plasticity in the excitatory synapse

Fernandes, D., & Carvalho, A. L. (2016) · Journal of Neurochemistry · doi:10.1111/jnc.13687 · Cited by 179

Structure of the Homer EVH1 Domain-Peptide Complex Reveals a New Twist in Polyproline Recognition

Beneken, J., Tu, J. C., Xiao, B., Nuriya, M., Yuan, J. P., Worley, P. F., & Leahy, D. J. (2000) · Neuron · doi:10.1016/s0896-6273(00)81145-9 · Cited by 169

Metabotropic Glutamate Receptor Subtype 5 Antagonists MPEP and MTEP

Lea, P. M., & Faden, A. I. (2006) · CNS Drug Reviews · doi:10.1111/j.1527-3458.2006.00149.x · Cited by 168

Signaling complex formation of phospholipase Cβ4 with metabotropic glutamate receptor type 1α and 1,4,5‐trisphosphate receptor at the perisynapse and endoplasmic reticulum in the mouse brain

Nakamura, M., Sato, K., Fukaya, M., Araishi, K., Aiba, A., Kano, M., & Watanabe, M. (2004) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2004.03768.x · Cited by 170

Signaling at zero G: G-protein-independent functions for 7-TM receptors

Brzostowski, J. A., & Kimmel, A. R. (2001) · Trends in Biochemical Sciences · doi:10.1016/s0968-0004(01)01804-7 · Cited by 162

Ligand-induced rearrangement of the dimeric metabotropic glutamate receptor 1α

Tateyama, M., Abe, H., Nakata, H., Saito, O., & Kubo, Y. (2004) · Nature Structural & Molecular Biology · doi:10.1038/nsmb770 · Cited by 166

Networks of neurons, networks of genes: An integrated view of memory consolidation

Miyashita, T., Kubík, Š., Lewandowski, G. A., & Guzowski, J. F. (2007) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2007.08.012 · Cited by 164

Homer2 Is Necessary for EtOH-Induced Neuroplasticity

Szumlinski, K. K., Lominac, K. D., Oleson, E. B., Walker, J. K., Mason, A. R., Dehoff, M. H., Klugman, M., Cagle, S., Welt, K., During, M. J., et al. (2005) · Journal of Neuroscience · doi:10.1523/jneurosci.1529-05.2005 · Cited by 160

A Library of 7TM Receptor C-terminal Tails

Heydorn, A., Søndergaard, B. P., Ersbøll, B. K., Holst, B., Nielsen, F. C., Haft, C. R., Whistler, J. L., & Schwartz, T. W. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m406169200 · Cited by 158

New perspectives for the development of selective metabotropic glutamate receptor ligands

Pin, J., Colle, C. D., Bessis, A., & Acher, F. (1999) · European Journal of Pharmacology · doi:10.1016/s0014-2999(99)00258-7 · Cited by 158

Crystal Structure of the Ligand Binding Suppressor Domain of Type 1 Inositol 1,4,5-Trisphosphate Receptor

Bosanac, I., Yamazaki, H., Matsuura, T., Michikawa, T., Mikoshiba, K., & Ikura, M. (2005) · Molecular Cell · doi:10.1016/j.molcel.2004.11.047 · Cited by 158

Gating of Store-Operated Channels by Conformational Coupling to Ryanodine Receptors

Kiselyov, K. I., Shin, D. M., Wang, Y., Pessah, I. N., Allen, P. D., & Muallem, S. (2000) · Molecular Cell · doi:10.1016/s1097-2765(00)00041-1 · Cited by 155

Modulation of Type 1 Inositol (1,4,5)-Trisphosphate Receptor Function by Protein Kinase A and Protein Phosphatase 1α

Tang, T.-S., Tu, H., Wang, Z., & Борисович, Б. И. (2003) · Journal of Neuroscience · doi:10.1523/jneurosci.23-02-00403.2003 · Cited by 155

EVH1 domains: structure, function and interactions

Ball, L., Jarchau, T., Oschkinat, H., & Walter, U. (2001) · FEBS Letters · doi:10.1016/s0014-5793(01)03291-4 · Cited by 152

Sharpin, a Novel Postsynaptic Density Protein That Directly Interacts with the Shank Family of Proteins

Lim, S., Sala, C., Yoon, J., Park, S., Kuroda, S., Sheng, M., & Kim, E. (2001) · Molecular and Cellular Neuroscience · doi:10.1006/mcne.2000.0940 · Cited by 151

Homer-Dependent Cell Surface Expression of Metabotropic Glutamate Receptor Type 5 in Neurons

Ango, F., Robbe, D., Tu, J. C., Xiao, B., Worley, P. F., Pin, J., Bockaert, J., & Fagni, L. (2002) · Molecular and Cellular Neuroscience · doi:10.1006/mcne.2002.1100 · Cited by 155

Binge Drinking Upregulates Accumbens mGluR5-Homer2-PI3K Signaling: Functional Implications for Alcoholism

Cozzoli, D. K., Goulding, S. P., Zhang, P. W., Xiao, B., Hu, J. H., Ary, A. W., Obara, I., Rahn, A., Abou-Ziab, H., Tyrrel, B., et al. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.5900-08.2009 · Cited by 149

Critical Regions for Activation Gating of the Inositol 1,4,5-Trisphosphate Receptor

Uchida, K., Miyauchi, H., Furuichi, T., Michikawa, T., & Mikoshiba, K. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m300646200 · Cited by 151

Axon/Dendrite Targeting of Metabotropic Glutamate Receptors by Their Cytoplasmic Carboxy-Terminal Domains

Stowell, J. N., & Craig, A. M. (1999) · Neuron · doi:10.1016/s0896-6273(00)80707-2 · Cited by 149

Association of Ca V 1.3 L-Type Calcium Channels with Shank

Zhang, H., Maximov, A., Fu, Y., Xu, F., Tang, T.-S., Tkatch, T., Surmeier, D. J., & Борисович, Б. И. (2005) · Journal of Neuroscience · doi:10.1523/jneurosci.4554-04.2005 · Cited by 148

Presynaptic Clustering of mGluR7a Requires the PICK1 PDZ Domain Binding Site

Boudin, H., Doan, A., Xia, J., Shigemoto, R., Huganir, R. L., Worley, P. F., & Craig, A. M. (2000) · Neuron · doi:10.1016/s0896-6273(00)00127-6 · Cited by 149

Inositol 1,4,5‐trisphosphate receptors and their protein partners as signalling hubs

Prole, D. L., & Taylor, C. W. (2016) · The Journal of Physiology · doi:10.1113/jp271139 · Cited by 150

Homer Regulates Gain of Ryanodine Receptor Type 1 Channel Complex

Feng, W., Tu, J., Yang, T., Vernon, P. S., Allen, P. D., Worley, P. F., & Pessah, I. N. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m207675200 · Cited by 146

Allosteric modulators of group I metabotropic glutamate receptors: novel subtype-selective ligands and therapeutic perspectives

Gasparini, F. (2002) · Current Opinion in Pharmacology · doi:10.1016/s1471-4892(01)00119-9 · Cited by 146

Homer as Both a Scaffold and Transduction Molecule

Fagni, L., Worley, P. F., & Ango, F. (2002) · Science Signaling · doi:10.1126/stke.2002.137.re8 · Cited by 148

Dynamin 3 is a component of the postsynapse, where it interacts with mGluR5 and Homer

Gray, N. W., Fourgeaud, L., Huang, B., Chen, J., Cao, H., Oswald, B. J., Hémar, A., & McNiven, M. A. (2003) · Current Biology · doi:10.1016/s0960-9822(03)00136-2 · Cited by 143

Homer proteins in Ca2+ signaling by excitable and non-excitable cells

Worley, P. F., Zeng, W., Huang, G., Kim, J. Y., Shin, D. M., Kim, M. S., Yuan, J. P., Kiselyov, K. I., & Muallem, S. (2007) · Cell Calcium · doi:10.1016/j.ceca.2007.05.007 · Cited by 145

The Inositol 1,4,5-Trisphosphate Receptor (IP 3 R) and Its Regulators: Sometimes Good and Sometimes Bad Teamwork

Choe, C.-U., & Ehrlich, B. E. (2006) · Science s STKE · doi:10.1126/stke.3632006re15 · Cited by 142

Localization and Enhanced Current Density of the Kv4.2 Potassium Channel by Interaction with the Actin-Binding Protein Filamin

Petrecca, K., Miller, D. M., & Shrier, A. (2000) · Journal of Neuroscience · doi:10.1523/jneurosci.20-23-08736.2000 · Cited by 139

Direct Interaction Enables Cross-talk between Ionotropic and Group I Metabotropic Glutamate Receptors

Perroy, J., Raynaud, F., Homburger, V., Rousset, M.-C., Telley, L., Bockaert, J., & Fagni, L. (2008) · Journal of Biological Chemistry · doi:10.1074/jbc.m705661200 · Cited by 138

A Novel Ca2+-Independent Signaling Pathway to Extracellular Signal-Regulated Protein Kinase by Coactivation of NMDA Receptors and Metabotropic Glutamate Receptor 5 in Neurons

Yang, L., Mao, L., Tang, Q., Samdani, S., Liu, Z., & Wang, J. Q. (2004) · Journal of Neuroscience · doi:10.1523/jneurosci.2496-04.2004 · Cited by 138

A reduced number of metabotropic glutamate subtype 5 receptors are associated with constitutive homer proteins in a mouse model of fragile X syndrome

Giuffrida, R., Musumeci, S., D'Antoni, S., Bonaccorso, C. M., Giuffrida-Stella, A. M., Oostra, B. A., & Catania, M. V. (2005) · The Journal of Neuroscience · doi:10.1523/jneurosci.0932-05.2005 · Cited by 141

Homer 1a uncouples metabotropic glutamate receptor 5 from postsynaptic effectors

Kammermeier, P. J., & Worley, P. F. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0608991104 · Cited by 135

Activity-regulated genes as mediators of neural circuit plasticity

Leslie, J. H., & Nedivi, E. (2011) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2011.05.002 · Cited by 136

Protein Kinase A and Two Phosphatases Are Components of the Inositol 1,4,5-Trisphosphate Receptor Macromolecular Signaling Complex

deSouza, N., Reiken, S. R., Ondriaš, K., Yang, Y., Matkovich, S. J., & Marks, A. R. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m207059200 · Cited by 134

SRGAP2 and Its Human-Specific Paralog Co-Regulate the Development of Excitatory and Inhibitory Synapses

Fossati, M., Pizzarelli, R., Schmidt, E. R., Kupferman, J. V., Stroebel, D., Polleux, F., & Charrier, C. (2016) · Neuron · doi:10.1016/j.neuron.2016.06.013 · Cited by 133

The sigma-1 receptor mediates the beneficial effects of pridopidine in a mouse model of Huntington disease

Rijsketic, D. R., Wu, J., Geva, M., Kusko, R. L., Grossman, I., Hayden, M. R., & Борисович, Б. И. (2016) · Neurobiology of Disease · doi:10.1016/j.nbd.2016.10.006 · Cited by 132

Maximizing Peptide Identification Events in Proteomic Workflows Using Data-Dependent Acquisition (DDA)

Bateman, N. W., Goulding, S. P., Shulman, N., Gadok, A. K., Szumlinski, K. K., MacCoss, M. J., & Wu, C. C. (2013) · Molecular & Cellular Proteomics · doi:10.1074/mcp.m112.026500 · Cited by 137

Synaptic scaffolding protein Homer1a protects against chronic inflammatory pain

Tappe‐Theodor, A., Klugmann, M., Luo, C., Hirlinger, D., Agarwal, N. K., Benrath, J., Ehrengruber, M. U., During, M. J., & Kuner, R. (2006) · Nature Medicine · doi:10.1038/nm1406 · Cited by 130

Involvement of unique leucine-zipper motif of PSD-Zip45 (Homer 1c/vesl-1L) in group 1 metabotropic glutamate receptor clustering

Tadokoro, S., Tachibana, T., Imanaka, T., Nishida, W., & Sobue, K. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.24.13801 · Cited by 130

NMDA Receptor Stimulation and Brain-Derived Neurotrophic Factor Upregulate Homer 1a mRNA via the Mitogen-Activated Protein Kinase Cascade in Cultured Cerebellar Granule Cells

Sato, M., Suzuki, K., & Nakanishi, S. (2001) · Journal of Neuroscience · doi:10.1523/jneurosci.21-11-03797.2001 · Cited by 129

Cytoskeletal dynamics in dendritic spines: direct modulation by glutamate receptors?

van Rossum, D., & Hanisch, U. (1999) · Trends in Neurosciences · doi:10.1016/s0166-2236(99)01404-6 · Cited by 128

Glutamatergic Postsynaptic Density Protein Dysfunctions in Synaptic Plasticity and Dendritic Spines Morphology: Relevance to Schizophrenia and Other Behavioral Disorders Pathophysiology, and Implications for Novel Therapeutic Approaches

de Bartolomeis, A., Latte, G., Tomasetti, C., & Iasevoli, F. (2013) · Molecular Neurobiology · doi:10.1007/s12035-013-8534-3 · Cited by 127

Homers regulate drug-induced neuroplasticity: Implications for addiction

Szumlinski, K. K., Ary, A. W., & Lominac, K. D. (2007) · Biochemical Pharmacology · doi:10.1016/j.bcp.2007.07.031 · Cited by 131

G-protein-independent signaling by G-protein-coupled receptors

Heuss, C., & Gerber, U. R. (2000) · Trends in Neurosciences · doi:10.1016/s0166-2236(00)01643-x · Cited by 125

Distinct physiological roles of the Gq‐coupled metabotropic glutamate receptors co‐expressed in the same neuronal populations

Valenti, O., Conn, P. J., & Marino, M. J. (2002) · Journal of Cellular Physiology · doi:10.1002/jcp.10081 · Cited by 125

Intracellular Ca2+ pools in neuronal signalling

Rizzuto, R. (2001) · Current Opinion in Neurobiology · doi:10.1016/s0959-4388(00)00212-9 · Cited by 123

Spatial Segregation and Interaction of Calcium Signalling Mechanisms in Rat Hippocampal CA1 Pyramidal Neurons

Nakamura, T., Lasser‐Ross, N., Nakamura, K. M., & Ross, W. N. (2002) · The Journal of Physiology · doi:10.1113/jphysiol.2002.020362 · Cited by 123

Protein–protein interactions at G-protein-coupled receptors

Milligan, G., & White, J. H. M. (2001) · Trends in Pharmacological Sciences · doi:10.1016/s0165-6147(00)01801-0 · Cited by 123

The Na-K-ATPase and Calcium-Signaling Microdomains

Tian, J., & Xie, Z. (2008) · Physiology · doi:10.1152/physiol.00008.2008 · Cited by 122

Structural insights into the regulatory mechanism of IP3 receptor

Bosanac, I., Michikawa, T., Mikoshiba, K., & Ikura, M. (2004) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2004.09.016 · Cited by 124

Rapid Redistribution of the Postsynaptic Density Protein PSD-Zip45 (Homer 1c) and Its Differential Regulation by NMDA Receptors and Calcium Channels

Okabe, S., Urushido, T., Konno, D., Okado, H., & Sobue, K. (2001) · Journal of Neuroscience · doi:10.1523/jneurosci.21-24-09561.2001 · Cited by 119

mGluR1/5 subtype‐specific calcium signalling and induction of long‐term potentiation in rat hippocampal oriens/alveus interneurones

Topolnik, L., Azzi, M., Morin, F., Kougioumoutzakis, A., & Lacaille, J. (2006) · The Journal of Physiology · doi:10.1113/jphysiol.2006.112896 · Cited by 118

Down-regulation of Homer1b/c attenuates glutamate-mediated excitotoxicity through endoplasmic reticulum and mitochondria pathways in rat cortical neurons

Chen, T., Fei, F., Jiang, X., Zhang, L., Qu, Y., Huo, K., & Fei, Z. (2011) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2011.10.451 · Cited by 120

Direct interaction of GluRδ2 with Shank scaffold proteins in cerebellar Purkinje cells

Uemura, T., Mori, H., & Mishina, M. (2004) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2004.02.007 · Cited by 126

Reciprocal signaling between translational control pathways and synaptic proteins in autism spectrum disorders

Santini, E., & Klann, E. (2014) · Science Signaling · doi:10.1126/scisignal.2005832 · Cited by 118

Glutamate Transmission and Addiction to Cocaine

Kalivas, P. W., McFarland, K., Bowers, M. S., Szumlinski, K. K., Xi, Z., & Baker, D. L. (2003) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1300.009 · Cited by 117

Homer 1 Mediates Store- and Inositol 1,4,5-Trisphosphate Receptor-dependent Translocation and Retrieval of TRPC3 to the Plasma Membrane

Kim, J. Y., Zeng, W., Kiselyov, K. I., Yuan, J. P., Dehoff, M. H., Mikoshiba, K., Worley, P. F., & Muallem, S. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m602496200 · Cited by 117

Activation of Metabotropic Glutamate Receptor 1 Accelerates NMDA Receptor Trafficking

Lan, J.-Y., Skeberdis, V. A., Jover, T., Zheng, X., Bennett, M. V. L., & Zukin, R. S. (2001) · Journal of Neuroscience · doi:10.1523/jneurosci.21-16-06058.2001 · Cited by 118

Regulators of G Protein Signaling

Burchett, S. A. (2000) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2000.0751335.x · Cited by 114

Fast Subplasma Membrane Ca2+Transients Control Exo-Endocytosis of Synaptic-Like Microvesicles in Astrocytes

Marchaland, J., Calì, C., Voglmaier, S. M., Li, H., Regazzi, R., Edwards, R. H., & Bezzi, P. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.0040-08.2008 · Cited by 113

Structure of EVH1, a novel proline-rich ligand-binding module involved in cytoskeletal dynamics and neural function.

Fedorov, A. A., Fedorov, E. V., Gertler, F. B., & Almo, S. C. (1999) · Nature Structural Biology · doi:10.1038/10717 · Cited by 113

Accumbens Homer2 Overexpression Facilitates Alcohol-Induced Neuroplasticity in C57BL/6J Mice

Szumlinski, K. K., Ary, A. W., Lominac, K. D., Klugmann, M., & Kippin, T. E. (2007) · Neuropsychopharmacology · doi:10.1038/sj.npp.1301473 · Cited by 109

The γ‐aminobutyric acid receptor B, but not the metabotropic glutamate receptor type‐1, associates with lipid rafts in the rat cerebellum

Becher, A., White, J. H. M., & McIlhinney, R. A. J. (2001) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2001.00614.x · Cited by 109

Functional Consequences of Mutations in Postsynaptic Scaffolding Proteins and Relevance to Psychiatric Disorders

Ting, J. T., Peça, J., & Feng, G. (2012) · Annual Review of Neuroscience · doi:10.1146/annurev-neuro-062111-150442 · Cited by 110

Surface clustering of metabotropic glutamate receptor 1 induced by long Homer proteins

Kammermeier, P. J. (2006) · BMC Neuroscience · doi:10.1186/1471-2202-7-1 · Cited by 108

Alteration of second messengers during acute cerebral ischemia – adenylate cyclase, cyclic AMP-dependent protein kinase, and cyclic AMP response element binding protein

Tanaka, K. (2001) · Progress in Neurobiology · doi:10.1016/s0301-0082(01)00002-8 · Cited by 107

Differential expression of Homer family proteins in the developing mouse brain

Shiraishi, Y., Mizutani, A., Yuasa, S., Mikoshiba, K., & Furuichi, T. (2004) · The Journal of Comparative Neurology · doi:10.1002/cne.20116 · Cited by 107

The "Ups and Downs" of Signaling Cascades in Addiction

Dorit Ron, A., & Jurd, R. (2005) · Science s STKE · doi:10.1126/stke.3092005re14 · Cited by 107

The state of GPCR research in 2004

Participants., T. N. R. D. D. G. Q., & Ellis, C. (2004) · Nature Reviews Drug Discovery · doi:10.1038/nrd1458 · Cited by 106

‘Medusa head ataxia’: the expanding spectrum of Purkinje cell antibodies in autoimmune cerebellar ataxia. Part 1: Anti-mGluR1, anti-Homer-3, anti-Sj/ITPR1 and anti-CARP VIII

Jarius, S., & Wildemann, B. (2015) · Journal of Neuroinflammation · doi:10.1186/s12974-015-0356-y · Cited by 105

Homer1a-Dependent Crosstalk Between NMDA and Metabotropic Glutamate Receptors in Mouse Neurons

Bertaso, F., Roussignol, G., Worley, P. F., Bockaert, J., Fagni, L., & Ango, F. (2010) · PLoS ONE · doi:10.1371/journal.pone.0009755 · Cited by 105

Cupidin, an Isoform of Homer/Vesl, Interacts with the Actin Cytoskeleton and Activated Rho Family Small GTPases and Is Expressed in Developing Mouse Cerebellar Granule Cells

Shiraishi, Y., Mizutani, A., Bito, H., Fujisawa, K., Narumiya, S., Mikoshiba, K., & Furuichi, T. (1999) · Journal of Neuroscience · doi:10.1523/jneurosci.19-19-08389.1999 · Cited by 104

Neuronal and glial 3D chromatin architecture informs the cellular etiology of brain disorders

Hu, B., Won, H., Mah, W., Park, R. B., Kassim, B., Spiess, K., Kozlenkov, A., Crowley, C. A., Pochareddy, S., The PsychENCODE Consortium, et al. (2021) · Nature Communications · doi:10.1038/s41467-021-24243-0 · Cited by 103

Behavioral sensitization to cocaine is associated with increased glutamate receptor trafficking to the postsynaptic density after extended withdrawal period

Ghasemzadeh, M. B., Mueller, C., & Vasudevan, P. (2009) · Neuroscience · doi:10.1016/j.neuroscience.2008.10.027 · Cited by 107

Multiple mechanisms limit the duration of wakefulness in Drosophila brain

Zimmerman, J. E., Rizzo, W., Shockley, K. R., Raizen, D. M., Naidoo, N. N., Mackiewicz, M., Churchill, G. A., & Pack, A. I. (2006) · Physiological Genomics · doi:10.1152/physiolgenomics.00030.2006 · Cited by 105

Applications of display technology in protein analysis

Li, M. (2000) · Nature Biotechnology · doi:10.1038/82355 · Cited by 103

Ca2+ signaling microdomains:platforms for the assembly andregulation of TRPC channels

Ambudkar, I. S. (2005) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2005.11.008 · Cited by 102

Isoform specificity of protein kinase Cs in synaptic plasticityPreprint

Sossin, W. S. (2007) · Learning & Memory · doi:10.1101/lm.469707 · Cited by 102

Homer Proteins Regulate Coupling of Group I Metabotropic Glutamate Receptors to N-Type Calcium and M-Type Potassium Channels

Kammermeier, P. J., Xiao, B., Tu, J. C., Worley, P. F., & Ikeda, S. R. (2000) · Journal of Neuroscience · doi:10.1523/jneurosci.20-19-07238.2000 · Cited by 195

New Insights Into mGluRs Function in the Substantia Nigra Pars Compacta

Guatteo, E., Berretta, N., Tozzi, A., Caputi, L., Paolucci, E., Bernardi, G., & Mercuri, N. B. (2002) · Advances in behavioral biology · doi:10.1007/978-1-4615-0715-4_24 · Cited by 1

Down-regulation of Homer1b/c attenuates group I metabotropic glutamate receptors dependent Ca2+ signaling through regulating endoplasmic reticulum Ca2+ release in PC12 cells

Lv, M.-M., Cheng, Y.-C., Xiao, Z.-B., Sun, M., Ren, P., & Sun, X. (2014) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2014.07.044 · Cited by 18

Endogenous Homer Proteins Regulate Metabotropic Glutamate Receptor Signaling in Neurons

Kammermeier, P. J. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.1830-08.2008 · Cited by 87

Homer Regulates the Association of Group 1 Metabotropic Glutamate Receptors with Multivalent Complexes of Homer-Related, Synaptic Proteins

Xiao, B., Tu, J. C., Petralia, R. S., Yuan, J. P., Doan, A., Breder, C. D., Ruggiero, A. M., Lanahan, A. A., Wenthold, R. J., & Worley, P. F. (1998) · Neuron · doi:10.1016/s0896-6273(00)80588-7 · Cited by 649