Homer Binds a Novel Proline-Rich Motif and Links Group 1 Metabotropic Glutamate Receptors with IP3 Receptors

PHARMACOLOGY AND FUNCTIONS OF METABOTROPIC GLUTAMATE RECEPTORS

Conn, P. J., & Pin, J. (1997) · The Annual Review of Pharmacology and Toxicology · doi:10.1146/annurev.pharmtox.37.1.205 · Cited by 3,083

Sequence and expression of a metabotropic glutamate receptor

Masu, M., Tanabe, Y., Tsuchida, K., Shigemoto, R., & Nakanishi, S. (1991) · Nature · doi:10.1038/349760a0 · Cited by 1,216

Homer: a protein that selectively binds metabotropic glutamate receptors

Brakeman, P., Lanahan, A. A., O’Brien, R., Roche, K. W., Barnes, C. A., Huganir, R. L., & Worley, P. F. (1997) · Nature · doi:10.1038/386284a0 · Cited by 1,115

Structural basis for the binding of proline-rich peptides to SH3 domains

Yu, H., Chen, J., Feng, S., Dalgarno, D. C., Brauer, A. W., & Schrelber, S. L. (1994) · Cell · doi:10.1016/0092-8674(94)90367-0 · Cited by 1,003

A family of metabotropic glutamate receptors

Tanabe, Y., Masu, M., Ishii, T., Shigemoto, R., & Nakanishi, S. (1992) · Neuron · doi:10.1016/0896-6273(92)90118-w · Cited by 940

The role of excitatory amino acids in behavioral sensitization to psychomotor stimulants

Wolf, M. E. (1998) · Progress in Neurobiology · doi:10.1016/s0301-0082(97)00090-7 · Cited by 934

The metabotropic glutamate receptor (mGluRlα) is concentrated at perisynaptic membrane of neuronal subpopulations as detected by immunogold reaction

Baude, A., Nusser, Z., Roberts, J. D. B., Mulvihill, E., Jeffrey Mcllhinney, R. A., & Somogyi, P. (1993) · Neuron · doi:10.1016/0896-6273(93)90086-7 · Cited by 927

A family of metabotropic glutamate receptors

Tanabe, Y. (1992) · Medical Entomology and Zoology · doi:10.11501/3061113 · Cited by 879

Wiskott–Aldrich Syndrome Protein, a Novel Effector for the GTPase CDC42Hs, Is Implicated in Actin Polymerization

Symons, M. H., Derry, J. M. J., Karlak, B., Jiang, S., Lemahieu, V., McCormick, F. P., Francke, U., & Abo, A. (1996) · Cell · doi:10.1016/s0092-8674(00)81050-8 · Cited by 830

Molecular characterization of a novel metabotropic glutamate receptor mGluR5 coupled to inositol phosphate/Ca2+ signal transduction.

Abe, T., Sugihara, H., Nawa, H., Shigemoto, R., Mizuno, N., & Nakanishi, S. (1992) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)42219-3 · Cited by 815

Central sensitization: a generator of pain hypersensitivity by central neural plasticity

Latremoliere, A., & Woolf, C. J. (2009) · The Journal of Pain · doi:10.1016/j.jpain.2009.06.012 · Cited by 3,913

Metabotropic Glutamate Receptors: Physiology, Pharmacology, and Disease

Niswender, C. M., & Conn, P. J. (2010) · The Annual Review of Pharmacology and Toxicology · doi:10.1146/annurev.pharmtox.011008.145533 · Cited by 1,889

Molecular tinkering of G protein‐coupled receptors: an evolutionary success

Bockaert, J., & Pin, J. (1999) · The EMBO Journal · doi:10.1093/emboj/18.7.1723 · Cited by 1,548

The importance of being proline: the interaction of proline‐rich motifs in signaling proteins with their cognate domains

Kay, B. K., Williamson, M. P., & Sudol, M. (2000) · The FASEB Journal · doi:10.1096/fasebj.14.2.231 · Cited by 1,214

Microdomains of Intracellular Ca2+: Molecular Determinants and Functional Consequences

Rizzuto, R., & Pozzan, T. (2005) · Physiological Reviews · doi:10.1152/physrev.00004.2005 · Cited by 1,201

Inositol Trisphosphate Receptor Ca2+Release Channels

Foskett, J. K., White, C., Cheung, K.-H., & Mak, D.-O. D. (2007) · Physiological Reviews · doi:10.1152/physrev.00035.2006 · Cited by 1,188

Coupling of mGluR/Homer and PSD-95 Complexes by the Shank Family of Postsynaptic Density Proteins

Tu, J. C., Xiao, B., Naisbitt, S. R., Yuan, J. P., Petralia, R. S., Brakeman, P., Doan, A., Aakalu, V. K., Lanahan, A. A., Sheng, M., et al. (1999) · Neuron · doi:10.1016/s0896-6273(00)80810-7 · Cited by 1,079

Shank, a Novel Family of Postsynaptic Density Proteins that Binds to the NMDA Receptor/PSD-95/GKAP Complex and Cortactin

Naisbitt, S., Kim, E., Tu, J. C., Xiao, B., Sala, C., Valtschanoff, J., Weinberg, R. J., Worley, P. F., & Sheng, M. (1999) · Neuron · doi:10.1016/s0896-6273(00)80809-0 · Cited by 1,009

The TRP Superfamily of Cation Channels

Montell, C. (2005) · Science s STKE · doi:10.1126/stke.2722005re3 · Cited by 1,020

The endoplasmic reticulum: a multifunctional signaling organelle

Berridge, M. J. (2002) · Cell Calcium · doi:10.1016/s0143416002001823 · Cited by 978

Cerebellar Long-Term Depression: Characterization, Signal Transduction, and Functional Roles

Ito, M. (2001) · Physiological Reviews · doi:10.1152/physrev.2001.81.3.1143 · Cited by 855

Arc/Arg3.1 interacts with the endocytic machinery to regulate AMPA receptor trafficking

Chowdhury, S., Shepherd, J. D., Okuno, H., Lyford, G., Petralia, R. S., Plath, N., Kuhl, D., Huganir, R. L., & Worley, P. F. (2006) · Neuron · doi:10.1016/j.neuron.2006.08.033 · Cited by 792

Synaptic Dysfunction in Neurodevelopmental Disorders Associated with Autism and Intellectual Disabilities

Zoghbi, H. Y., & Bear, M. F. (2012) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a009886 · Cited by 797

Regulation of Dendritic Spine Morphology and Synaptic Function by Shank and Homer

Sala, C., Piëch, V., Wilson, N. R., Passafaro, M., Liu, G., & Sheng, M. (2001) · Neuron · doi:10.1016/s0896-6273(01)00339-7 · Cited by 716

Physiology and Pathophysiology of the Calcium Store in the Endoplasmic Reticulum of Neurons

Verkhratsky, A. (2004) · Physiological Reviews · doi:10.1152/physrev.00004.2004 · Cited by 718

Pathways modulating neural KCNQ/M (Kv7) potassium channels

Delmas, P., & Brown, D. A. (2005) · Nature Reviews Neuroscience · doi:10.1038/nrn1785 · Cited by 686

Ena/VASP Proteins: Regulators of the Actin Cytoskeleton and Cell Migration

Krause, M., Dent, E. W., Bear, J. E., Loureiro, J., & Gertler, F. B. (2003) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cellbio.19.050103.103356 · Cited by 682

Evolution, structure, and activation mechanism of family 3/C G-protein-coupled receptors

Pin, J.-P., Galvez, T., & Prézeau, L. (2003) · Pharmacology & Therapeutics · doi:10.1016/s0163-7258(03)00038-x · Cited by 662

Metabotropic glutamate receptors: From the workbench to the bedside

Nicoletti, F., Bockaert, J., Collingridge, G. L., Conn, P. J., Ferraguti, F., Schoepp, D. D., Wroblewski, J. T., & Pin, J. (2010) · Neuropharmacology · doi:10.1016/j.neuropharm.2010.10.022 · Cited by 680

Homer Regulates the Association of Group 1 Metabotropic Glutamate Receptors with Multivalent Complexes of Homer-Related, Synaptic Proteins

Xiao, B., Tu, J. C., Petralia, R. S., Yuan, J. P., Doan, A., Breder, C. D., Ruggiero, A. M., Lanahan, A. A., Wenthold, R. J., & Worley, P. F. (1998) · Neuron · doi:10.1016/s0896-6273(00)80588-7 · Cited by 649

Metabotropic glutamate receptors

Ferraguti, F., & Shigemoto, R. (2006) · Cell and Tissue Research · doi:10.1007/s00441-006-0266-5 · Cited by 682

Glutamatergic Signaling in the Central Nervous System: Ionotropic and Metabotropic Receptors in Concert

Reiner, A., & Levitz, J. (2018) · Neuron · doi:10.1016/j.neuron.2018.05.018 · Cited by 685

Local Calcium Signaling in Neurons

Augustine, G. J., Santamaría, F., & Tanaka, K. (2003) · Neuron · doi:10.1016/s0896-6273(03)00639-1 · Cited by 617

Molecular mechanisms of ligand binding, signaling, and regulation within the superfamily of G-protein-coupled receptors: molecular modeling and mutagenesis approaches to receptor structure and function

Kristiansen, K. (2004) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2004.05.002 · Cited by 631

The Shank family of scaffold proteins

Sheng, M., & Kim, E. (2000) · Journal of Cell Science · doi:10.1242/jcs.113.11.1851 · Cited by 578

Elongation Factor 2 and Fragile X Mental Retardation Protein Control the Dynamic Translation of Arc/Arg3.1 Essential for mGluR-LTD

Park, S., Park, J. M., Kim, S., Kim, J.-A., Shepherd, J. D., Smith-Hicks, C. L., Chowdhury, S., Kaufmann, W., Kuhl, D., Ryazanov, A. G., et al. (2008) · Neuron · doi:10.1016/j.neuron.2008.05.023 · Cited by 516

Homer1a drives homeostatic scaling-down of excitatory synapses during sleep

Diering, G. H., Nirujogi, R. S., Roth, R. H., Worley, P. F., Pandey, A., & Huganir, R. L. (2017) · Science · doi:10.1126/science.aai8355 · Cited by 516

Homer Binds TRPC Family Channels and Is Required for Gating of TRPC1 by IP3 Receptors

Yuan, J. P., Kiselyov, K. I., Shin, D. M., Chen, J., Shcheynikov, N., Kang, S. H., Dehoff, M. H., Schwarz, M. K., Seeburg, P. H., Muallem, S., et al. (2003) · Cell · doi:10.1016/s0092-8674(03)00716-5 · Cited by 507

Fine-tuning of GPCR activity by receptor-interacting proteins

Ritter, S. L., & Hall, R. A. (2009) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2803 · Cited by 479

Synaptic clustering of AMPA receptors by the extracellular immediate-early gene product narp.

O’Brien, R. J., Xu, D., Petralia, R. S., Steward, O., Huganir, R. L., & Worley, P. (1999) · Neuron · doi:10.1016/s0896-6273(00)80782-5 · Cited by 471

Spine loss and other dendritic abnormalities in epilepsy

Swann, J. W., Al‐Noori, S., Jiang, M., & Lee, C. L. (2000) · Hippocampus · doi:10.1002/1098-1063(2000)10:5 · Cited by 268

The organisation and functions of local Ca2+ signals

Bootman, M. D., Lipp, P., & Berridge, M. J. (2001) · Journal of Cell Science · doi:10.1242/jcs.114.12.2213 · Cited by 449

Inositol 1,4,5-Trisphosphate Receptors as Signal Integrators

Patterson, R. L., Boehning, D. F., & Snyder, S. H. (2004) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.73.071403.161303 · Cited by 438

Metabotropic Glutamate Receptors 1 and 5 Differentially Regulate CA1 Pyramidal Cell Function

Mannaioni, G., Marino, M. J., Valenti, O., Traynelis, S. F., & Conn, P. J. (2001) · Journal of Neuroscience · doi:10.1523/jneurosci.21-16-05925.2001 · Cited by 441

Cortactin: coupling membrane dynamics to cortical actin assembly

Weed, S. A., & Parsons, J. T. (2001) · Oncogene · doi:10.1038/sj.onc.1204783 · Cited by 416

Agonist-independent activation of metabotropic glutamate receptors by the intracellular protein Homer

Ango, F., Prézeau, L., Müller, T. H., Tu, J. C., Xiao, B., Worley, P. F., Pin, J., Bockaert, J., & Fagni, L. (2001) · Nature · doi:10.1038/35082096 · Cited by 410

Homer: a link between neural activity and glutamate receptor function

Xiao, B., Tu, J. C., & Worley, P. F. (2000) · Current Opinion in Neurobiology · doi:10.1016/s0959-4388(00)00087-8 · Cited by 406

Structural, signalling and regulatory properties of the group I metabotropic glutamate receptors: prototypic family C G-protein-coupled receptors

Hermans, E., & Challiss, R. A. J. (2001) · Biochemical Journal · doi:10.1042/0264-6021:3590465 · Cited by 414

IP3 receptor/Ca2+ channel: from discovery to new signaling concepts

Mikoshiba, K. (2007) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2007.04825.x · Cited by 409

Identification of Proteins in the Postsynaptic Density Fraction by Mass Spectrometry

Walikonis, R. S., Jensen, O. N., Mann, M., Provance, D. W., Mercer, J. A., & Kennedy, M. B. (2000) · Journal of Neuroscience · doi:10.1523/jneurosci.20-11-04069.2000 · Cited by 395

α1-Adrenoceptor subtypes

Zhong, H., & Minneman, K. P. (1999) · European Journal of Pharmacology · doi:10.1016/s0014-2999(99)00222-8 · Cited by 386

Expansion of the calcium hypothesis of brain aging and Alzheimer's disease: minding the store

Thibault, O., Gant, J. C., & Landfield, P. W. (2007) · Aging Cell · doi:10.1111/j.1474-9726.2007.00295.x · Cited by 377

Physiology, Phylogeny, and Functions of the TRP Superfamily of Cation Channels

Montell, C. (2001) · Science s STKE · doi:10.1126/stke.2001.90.re1 · Cited by 378

Subcellular Arrangement of Molecules for 2-Arachidonoyl-Glycerol-Mediated Retrograde Signaling and Its Physiological Contribution to Synaptic Modulation in the Striatum

Uchigashima, M., Narushima, M., Fukaya, M., Katona, I., Kano, M., & Watanabe, M. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.0448-07.2007 · Cited by 375

The Structure and Function of Proline Recognition Domains

Zarrinpar, A., Bhattacharyya, R. P., & Lim, W. A. (2003) · Science Signaling · doi:10.1126/stke.2003.179.re8 · Cited by 375

Glutamate receptor dynamics in dendritic microdomains.

Newpher, T. M., & Ehlers, M. D. (2008) · Neuron · doi:10.1016/j.neuron.2008.04.030 · Cited by 356

Regulation of GPCR activity, trafficking and localization by GPCR‐interacting proteins

Magalhães, A. C., Dunn, H. A., & Ferguson, S. S. G. (2011) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.2011.01552.x · Cited by 352

ProSAP/Shank proteins – a family of higher order organizing molecules of the postsynaptic density with an emerging role in human neurological disease

Boeckers, T. M., Bockmann, J., Kreutz, M. R., & Gundelfinger, E. D. (2002) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2002.00931.x · Cited by 349

Distribution of metabotropic glutamate receptor mGluR3 in the mouse CNS: differential location relative to pre- and postsynaptic sites

Tamaru, Y., Nomura, S., Mizuno, N., & Shigemoto, R. (2001) · Neuroscience · doi:10.1016/s0306-4522(01)00305-0 · Cited by 345

A Calcium-Responsive Transcription Factor, CaRF, that Regulates Neuronal Activity-Dependent Expression of BDNF

Tao, X., West, A. E., Chen, W. G., Corfas, G., & Greenberg, M. E. (2002) · Neuron · doi:10.1016/s0896-6273(01)00561-x · Cited by 339

Molecular organization of the postsynaptic specialization

Sheng, M. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.111146298 · Cited by 343

Smooth Muscle Ion Channels and Regulation of Vascular Tone in Resistance Arteries and Arterioles

Tykocki, N. R., Boerman, E. M., & Jackson, W. F. (2017) · Comprehensive physiology · doi:10.1002/cphy.c160011 · Cited by 387

Heptahelical Receptor Signaling: Beyond the G Protein Paradigm

Hall, R. A., Premont, R. T., & Lefkowitz, R. J. (1999) · The Journal of Cell Biology · doi:10.1083/jcb.145.5.927 · Cited by 326

The Homer family proteins.

Shiraishi‐Yamaguchi, Y., & Furuichi, T. (2007) · Genome biology · doi:10.1186/gb-2007-8-2-206 · Cited by 343

Glutamate, Glutamate Receptors, and Downstream Signaling Pathways

Willard, S. S., & Koochekpour, S. (2013) · International Journal of Biological Sciences · doi:10.7150/ijbs.6426 · Cited by 323

Molecular Mechanisms and Therapeutical Implications of Intramembrane Receptor/Receptor Interactions among Heptahelical Receptors with Examples from the Striatopallidal GABA Neurons

Agnati, L. F., Ferré, S., Lluı́s, C., Franco, R., & Fuxé, K. (2003) · Pharmacological Reviews · doi:10.1124/pr.55.3.2 · Cited by 323

Proteomic Analysis of in Vivo Phosphorylated Synaptic Proteins

Collins, M. O., Yu, L., Coba, M. P., Husi, H., Campuzano, I., Blackstock, W. P., Choudhary, J. S., & Grant, S. G. N. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m411220200 · Cited by 320

Inverse synaptic tagging of inactive synapses via dynamic interaction of Arc/Arg3.1 with CaMKIIβ

Okuno, H., Akashi, K., Ishii, Y., Yagishita-Kyo, N., Suzuki, K., Nonaka, M., Kawashima, T., Fujii, H., Takemoto-Kimura, S., Abe, M., et al. (2012) · Cell · doi:10.1016/j.cell.2012.02.062 · Cited by 310

Experience-Dependent Coincident Expression of the Effector Immediate-Early Genes Arc and Homer 1a in Hippocampal and Neocortical Neuronal Networks

Vazdarjanova, A. I., McNaughton, B. L., Barnes, C. A., Worley, P. F., & Guzowski, J. F. (2002) · Journal of Neuroscience · doi:10.1523/jneurosci.22-23-10067.2002 · Cited by 307

Characterization of the Shank Family of Synaptic Proteins

Lim, S., Naisbitt, S., Yoon, J., Hwang, J.-I., Suh, P.-G., Sheng, M., & Kim, E. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.41.29510 · Cited by 295

The EVH2 Domain of the Vasodilator-stimulated Phosphoprotein Mediates Tetramerization, F-actin Binding, and Actin Bundle Formation

Bachmann, C., Fischer, L., Walter, U., & Reinhard, M. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.33.23549 · Cited by 293

Inhibition of Dendritic Spine Morphogenesis and Synaptic Transmission by Activity-Inducible Protein Homer1a

Sala, C., Futai, K., Yamamoto, K., Worley, P. F., Hayashi, Y., & Sheng, M. (2003) · The Journal of Neuroscience · doi:10.1523/jneurosci.23-15-06327.2003 · Cited by 288

PI3 kinase enhancer–Homer complex couples mGluRI to PI3 kinase, preventing neuronal apoptosis

Rong, R., Ahn, J.-Y., Huang, H., Nagata, E., Kalman, D., Kapp, J. A., Tu, J., Worley, P. F., Snyder, S. H., & Ye, K. (2003) · Nature Neuroscience · doi:10.1038/nn1134 · Cited by 285

Complex interactions between mGluRs, intracellular Ca2+ stores and ion channels in neurons

Fagni, L., Chavis, P., Ango, F., & Bockaert, J. (2000) · Trends in Neurosciences · doi:10.1016/s0166-2236(99)01492-7 · Cited by 285

Regulation of G protein-coupled receptor export trafficking

Dong, C., Filipeanu, C. M., Duvernay, M. T., & Wu, G. (2006) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/j.bbamem.2006.09.008 · Cited by 280

Metabotropic glutamate receptors and neurodegenerative diseases

Ribeiro, F. M., Vieira, L. B., Pires, R. G. W., Olmo, R. P., & Ferguson, S. S. G. (2016) · Pharmacological Research · doi:10.1016/j.phrs.2016.11.013 · Cited by 288

Organization and functions of mGlu and GABAB receptor complexes

Pin, J., & Bettler, B. (2016) · Nature · doi:10.1038/nature20566 · Cited by 274

Postsynaptic Positioning of Endocytic Zones and AMPA Receptor Cycling by Physical Coupling of Dynamin-3 to Homer

Lu, J., Helton, T. D., Blanpied, T. A., Rácz, B., Newpher, T. M., Weinberg, R. J., & Ehlers, M. D. (2007) · Neuron · doi:10.1016/j.neuron.2007.06.041 · Cited by 273

Homeostatic Scaling Requires Group I mGluR Activation Mediated by Homer1a

Hu, J.-H., Park, J. M., Park, S. J., Xiao, B., Dehoff, M. H., Kim, S., Hayashi, T., Schwarz, M. K., Huganir, R. L., Seeburg, P. H., et al. (2010) · Neuron · doi:10.1016/j.neuron.2010.11.008 · Cited by 263

G protein-coupled receptor interacting proteins: Emerging roles in localization and signal transduction

Brady, A. E., & Limbird, L. E. (2002) · Cellular Signalling · doi:10.1016/s0898-6568(01)00239-x · Cited by 264

GPCR interacting proteins (GIP)

Bockaert, J., Fagni, L., Dumuis, A., & Marin, P. (2004) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2004.06.004 · Cited by 262

Effects of Sleep and Wake on Oligodendrocytes and Their Precursors

Bellesi, M., Pfister‐Genskow, M., Maret, S., Keleş, S., Tononi, G., & Cirelli, C. (2013) · Journal of Neuroscience · doi:10.1523/jneurosci.5102-12.2013 · Cited by 263

Recognition of Proline‐Rich Motifs by Protein–Protein‐Interaction Domains

Ball, L., Kühne, R., Schneider‐Mergener, J., & Oschkinat, H. (2005) · Angewandte Chemie International Edition · doi:10.1002/anie.200400618 · Cited by 256

Signaling Microdomains Define the Specificity of Receptor-Mediated InsP3 Pathways in Neurons

Delmas, P., Wanaverbecq, N., Abogadie, F. C., Mistry, M., & Brown, D. A. (2002) · Neuron · doi:10.1016/s0896-6273(02)00641-4 · Cited by 256

Cocaine‐induced neuroadaptations in glutamate transmission

Schmidt, H. D., & Pierce, R. C. (2010) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2009.05144.x · Cited by 267

Disrupted Homer scaffolds mediate abnormal mGluR5 function in a mouse model of fragile X syndrome

Ronesi, J. A., Collins, K. A., Hays, S. A., Tsai, N.-P., Guo, W., Birnbaum, S. G., Hu, J.-H., Worley, P. F., Gibson, J. R., & Huber, K. M. (2012) · Nature Neuroscience · doi:10.1038/nn.3033 · Cited by 251

The Scaffold Protein Homer1b/c Links Metabotropic Glutamate Receptor 5 to Extracellular Signal-Regulated Protein Kinase Cascades in Neurons

Mao, L., Yang, L., Tang, Q., Samdani, S., Zhang, G., & Wang, J. Q. (2005) · Journal of Neuroscience · doi:10.1523/jneurosci.4360-04.2005 · Cited by 250

Physiology and Pathology of Calcium Signaling in the Brain

Kawamoto, E. M., Vivar, C., & Camandola, S. (2012) · Frontiers in Pharmacology · doi:10.3389/fphar.2012.00061 · Cited by 264

Homer Interactions Are Necessary for Metabotropic Glutamate Receptor-Induced Long-Term Depression and Translational Activation

Ronesi, J. A., & Huber, K. M. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.5019-07.2008 · Cited by 244

Unraveling tumor–immune heterogeneity in advanced ovarian cancer uncovers immunogenic effect of chemotherapy

Jiménez-Sánchez, A., Cybulska, P., Mager, K. L., Koplev, S., Cast, O. M., Couturier, D., Memon, D., Selenica, P., Nikolovski, I., Mazaheri, Y., et al. (2020) · Nature Genetics · doi:10.1038/s41588-020-0630-5 · Cited by 248

The postsynaptic density

Boeckers, T. M. (2006) · Cell and Tissue Research · doi:10.1007/s00441-006-0274-5 · Cited by 263

Local Calcium Release in Dendritic Spines Required for Long-Term Synaptic Depression

Miyata, M., Finch, E., Khiroug, L., Hashimoto, K., Hayasaka, S., Oda, S., Inouye, M., Takagishi, Y., Augustine, G. J., & Kano, M. (2000) · Neuron · doi:10.1016/s0896-6273(00)00099-4 · Cited by 243

Structure of the Enabled/VASP Homology 1 Domain–Peptide Complex

Prehoda, K. E., Lee, D. J., & Lim, W. A. (1999) · Cell · doi:10.1016/s0092-8674(00)80757-6 · Cited by 237

The Function of Activity-Regulated Genes in the Nervous System

Loebrich, S., & Nedivi, E. (2009) · Physiological Reviews · doi:10.1152/physrev.00013.2009 · Cited by 241

The DLGAP family: neuronal expression, function and role in brain disorders

Rasmussen, A. H., Rasmussen, H. B., & Silahtaroglu, A. (2017) · Molecular Brain · doi:10.1186/s13041-017-0324-9 · Cited by 234

The ‘magic tail’ of G protein‐coupled receptors: an anchorage for functional protein networks

Bockaert, J., Marin, P., Dumuis, A., & Fagni, L. (2003) · FEBS Letters · doi:10.1016/s0014-5793(03)00453-8 · Cited by 233

Repeated Cocaine Administration Attenuates Group I Metabotropic Glutamate Receptor-Mediated Glutamate Release and Behavioral Activation: A Potential Role for Homer

Swanson, C. J., Baker, D. L., Carson, D., Worley, P. F., & Kalivas, P. W. (2001) · Journal of Neuroscience · doi:10.1523/jneurosci.21-22-09043.2001 · Cited by 228

Regulation of G Protein–Coupled Receptor Signaling by Scaffold Proteins

Hall, R. A., & Lefkowitz, R. J. (2002) · Circulation Research · doi:10.1161/01.res.0000037000.74258.03 · Cited by 227

Dendritic and Axonal Targeting of Type 5 Metabotropic Glutamate Receptor Is Regulated by Homer1 Proteins and Neuronal Excitation

Ango, F., Pin, J., Tu, J. C., Xiao, B., Worley, P. F., Bockaert, J., & Fagni, L. (2000) · Journal of Neuroscience · doi:10.1523/jneurosci.20-23-08710.2000 · Cited by 229

Molecular anatomy of the postsynaptic density.

Okabe, S. (2007) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2007.01.006 · Cited by 225

The inositol 1,4,5-trisphosphate receptors

Борисович, Б. И. (2005) · Cell Calcium · doi:10.1016/j.ceca.2005.06.030 · Cited by 226

Homer Proteins Regulate Sensitivity to Cocaine

Szumlinski, K. K., Dehoff, M. H., Kang, S. H., Frys, K. A., Lominac, K. D., Klugmann, M., Rohrer, J., Griffin, W. C., Toda, S., Champtiaux, N., et al. (2004) · Neuron · doi:10.1016/j.neuron.2004.07.019 · Cited by 228

TRPC1 Channels Are Critical for Hypertrophic Signaling in the Heart

Seth, M., Zhang, Z.-S., Mao, L., Graham, V., Burch, J. L., Stiber, J. A., Tsiokas, L., Winn, M. P., Abramowitz, J., Rockman, H. A., et al. (2009) · Circulation Research · doi:10.1161/circresaha.109.206581 · Cited by 223

Metabotropic glutamate receptor ligands as possible anxiolytic and antidepressant drugs

Pałucha-Poniewiera, A., & Pilc, A. (2007) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2007.04.007 · Cited by 225

Metabotropic Glutamate Subtype 5 Receptors Modulate Locomotor Activity and Sensorimotor Gating in Rodents

Kinney, G. G., Burno, M., Campbell, U. C., Hernández, L. M., Rodriguez, D. E., Bristow, L. J., & Conn, P. J. (2003) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.103.048702 · Cited by 219

Synaptic Activity-Induced Conversion of Intronic to Exonic Sequence in Homer 1 Immediate Early Gene Expression

Bottai, D., Guzowski, J. F., Schwarz, M. K., Kang, S. H., Xiao, B., Lanahan, A. A., Worley, P. F., & Seeburg, P. H. (2002) · Journal of Neuroscience · doi:10.1523/jneurosci.22-01-00167.2002 · Cited by 217

Metabotropic Glutamate 1 Receptor: Current Concepts and Perspectives

Ferraguti, F., Crepaldi, L., & Nicoletti, F. (2008) · Pharmacological Reviews · doi:10.1124/pr.108.000166 · Cited by 218

Homer 1b Regulates the Trafficking of Group I Metabotropic Glutamate Receptors

Roche, K. W., Tu, J. C., Petralia, R. S., Xiao, B., Wenthold, R. J., & Worley, P. F. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.36.25953 · Cited by 212

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Santulli, G., & Marks, A. R. (2015) · Current Molecular Pharmacology · doi:10.2174/1874467208666150507105105 · Cited by 216

Membrane Trafficking of G Protein–Coupled Receptors

Tan, C. M., Brady, A. E., Nickols, H. H., Wang, Q., & Limbird, L. E. (2004) · The Annual Review of Pharmacology and Toxicology · doi:10.1146/annurev.pharmtox.44.101802.121558 · Cited by 207

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Kammermeier, P. J., Xiao, B., Tu, J. C., Worley, P. F., & Ikeda, S. R. (2000) · Journal of Neuroscience · doi:10.1523/jneurosci.20-19-07238.2000 · Cited by 195

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Down-regulation of Homer1b/c attenuates group I metabotropic glutamate receptors dependent Ca2+ signaling through regulating endoplasmic reticulum Ca2+ release in PC12 cells

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