Inhibitory Autophosphorylation of CaMKII Controls PSD Association, Plasticity, and Learning

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Activity-Dependent Gating of CaMKII Autonomous Activity by Drosophila CASK

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Temporal and Region-Specific Requirements of αCaMKII in Spatial and Contextual Learning

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A mechanism for the inactivation of Ca2+/calmodulin-dependent protein kinase II during prolonged seizure activity and its consequence after the recovery from seizure activity in rats in vivo

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Regulation of CaMKII by α4/PP2Ac contributes to learning and memory

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A critical role for CaMKII in behavioral timescale synaptic plasticity in hippocampal CA1 pyramidal neurons

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Phosphorylation of CaMKII at Thr253 occurs in vivo and enhances binding to isolated postsynaptic densities

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α-Isoform of calcium-calmodulin-dependent protein kinase II and postsynaptic density protein 95 differentially regulate synaptic expression of NR2A– and NR2B–containing N-methyl-d-aspartate receptors in hippocampus

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CaM Kinases: From Memories to Addiction

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Functional implications of CaMKII alternative splicing

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The role of CaMKII autophosphorylation for NMDA receptor-dependent synaptic potentiation

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Phosphorylation Hypothesis of Sleep

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CaMKII Activation State Underlies Synaptic Labile Phase of LTP and Short-Term Memory Formation

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CaMKII T286 phosphorylation has distinct essential functions in three forms of long-term plasticity

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Amphetamine Action at the Cocaine- and Antidepressant-Sensitive Serotonin Transporter Is Modulated by αCaMKII

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αCaMKII autophosphorylation levels differ depending on subcellular localization

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Large deletions encompassing the TCOF1 and CAMK2A genes are responsible for Treacher Collins syndrome with intellectual disability

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The Delicate Bistability of CaMKII

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PTENα Modulates CaMKII Signaling and Controls Contextual Fear Memory and Spatial Learning

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CASK and CaMKII function in Drosophila memory

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N-Terminomic Changes in Neurons During Excitotoxicity Reveal Proteolytic Events Associated With Synaptic Dysfunctions and Potential Targets for Neuroprotection

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Molecular and behavioral changes associated with adult hippocampus-specific SynGAP1 knockoutPreprint

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Transient incubation of cultured hippocampal neurons in the absence of magnesium induces rhythmic and synchronized epileptiform-like activity

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Differential roles for CaM kinases in mediating excitation–morphogenesis coupling during formation and maturation of neuronal circuits

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Negative regulation of multifunctional Ca2+/calmodulin‐dependent protein kinases: physiological and pharmacological significance of protein phosphatases

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Development and validation of a sensitive entropy-based measure for the water maze

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The role of Ca 2+ -calmodulin stimulated protein kinase II in ischaemic stroke – A potential target for neuroprotective therapies

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Imaging single CaMKII holoenzymes at work by high-speed atomic force microscopy

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Ca2+/Calmodulin-Dependent Protein Kinase II (CaMKII)

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Muscarinic Modulation of SK2-Type K+Channels Promotes Intrinsic Plasticity in L2/3 Pyramidal Neurons of the Mouse Primary Somatosensory Cortex

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Trace eyeblink conditioning requires the hippocampus but not autophosphorylation of αCaMKII in micePreprint

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CaMKII autophosphorylation can occur between holoenzymes without subunit exchange

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The Role of Molecular Regulation and Targeting in Regulating Calcium/Calmodulin Stimulated Protein Kinases

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CaMKII Is Essential for the Function of the Enteric Nervous System

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Dopamine biases decisions by limiting temporal integration

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pT305-CaMKII stabilizes a learning-induced increase in AMPA receptors for ongoing memory consolidation after classical conditioning

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Ischemia and status epilepitcus result in enhanced phosphorylation of calcium and calmodulin-stimulated protein kinase II on threonine 253.

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Regulation of CaMKII by phospho-Thr253 or phospho-Thr286 sensitive targeting alters cellular function

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Intrinsic and synaptic determinants of receptive field plasticity in Purkinje cells of the mouse cerebellum

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Short-Term Extremely Low-Frequency Electromagnetic Field Inhibits Synaptic Plasticity of Schaffer Collateral-CA1 Synapses in Rat Hippocampus via the Ca2+/Calcineurin Pathway

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Role of inhibitory autophosphorylation of calcium/calmodulin-dependent kinase II (αCAMKII) in persistent (>24h) hippocampal LTP and in LTD facilitated by novel object-place learning and recognition in mice

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Understanding spike-time-dependent plasticity: A biologically motivated computational model

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Influences of hyperthermia-induced seizures on learning, memory and phosphorylative state of CaMKIIα in rat hippocampus

Xiong, Y., Zhou, H., & Zhang, L. (2014) · Brain Research · doi:10.1016/j.brainres.2014.02.026 · Cited by 19

Aging differentially alters the transcriptome and landscape of chromatin accessibility in the male and female mouse hippocampus

Achiro, J. M., Tao, Y., Gao, F., Lin, C.-H., Watanabe, M., Neumann, S., Coppola, G., Black, D. L., & Martin, K. C. (2024) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2024.1334862 · Cited by 21

Overexpression of hippocampal Ca2+/calmodulin‐dependent protein kinase II improves spatial memory

Poulsen, D. J., Standing, D., Bullshields, K., Spencer, K. B., Micevych, P. E., & Babcock, A. M. (2006) · Journal of Neuroscience Research · doi:10.1002/jnr.21163 · Cited by 18

CaMKII binding to GluN2B is important for massed spatial learning in the Morris water maze

Stein, I. S., Donaldson, M. S., & Hell, J. W. (2014) · F1000Research · doi:10.12688/f1000research.4660.1 · Cited by 20

Modulation of Murine Olivary Connexin 36 Gap Junctions by PKA and CaMKII

Bazzigaluppi, P., Isenia, S. C., Haasdijk, E. D., Elgersma, Y., Zeeuw, C. I. D., van der Giessen, R. S., & de Jeu, M. T. G. (2017) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2017.00397 · Cited by 17

Non-canonical heterogeneous cellular distribution and co-localization of CaMKIIα and CaMKIIβ in the spinal superficial dorsal horn

Larsson, M. (2017) · Brain Structure and Function · doi:10.1007/s00429-017-1566-0 · Cited by 17

In memoriam: John Lisman – commentaries on CaMKII as a memory molecule

Bear, M. F., Cooke, S. F., Giese, K.-P., Kaang, B., Kennedy, M. B., Kim, J., Morris, R., & Park, P. (2018) · Molecular Brain · doi:10.1186/s13041-018-0419-y · Cited by 17

Differential regulation of CaMKII inhibitor β protein expression after exposure to a novel context and during contextual fear memory formation

Radwańska, K., Jones, A. A. T., Mizuno, K., Pereira, G. S., Lucchesi, W., Alfano, I., Lach, A. A., Kaczmarek, L., Knapp, S., & Giese, K.-P. (2010) · Genes Brain & Behavior · doi:10.1111/j.1601-183x.2010.00595.x · Cited by 16

Pharmacological therapies for Angelman syndrome

Tan, W., & Bird, L. M. (2016) · Wiener Medizinische Wochenschrift · doi:10.1007/s10354-015-0408-z · Cited by 20

Propofol ameliorates electroconvulsive shock-induced learning and memory impairment by regulation of synaptic metaplasticity via autophosphorylation of CaMKIIa at Thr 305 in stressed rats

Ren, L., Zhang, F., Min, S., Hao, X., Qin, P., & Zhu, X. (2016) · Psychiatry Research · doi:10.1016/j.psychres.2016.03.053 · Cited by 16

Distinct roles of α- and βCaMKII in controlling long-term potentiation of GABAA-receptor mediated transmission in murine Purkinje cells

Gao, Z., van Woerden, G. M., Elgersma, Y., Zeeuw, C. I. D., & Hoebeek, F. E. (2014) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2014.00016 · Cited by 16

AMPA Receptor Regulation and the Reversal of Synaptic Plasticity – LTP, LTD, Depotentiation, and Dedepression

Lee, H., & Huganir, R. L. (2008) · Elsevier eBooks · doi:10.1016/b978-012370509-9.00035-8 · Cited by 15

Long-term potentiation can be induced in the CA1 region of hippocampus in the absence of αCaMKII T286-autophosphorylation

Villers, A., Giese, K. P., & Ris, L. (2014) · Learning & Memory · doi:10.1101/lm.035972.114 · Cited by 16

Modelling the dynamics of CaMKII–NMDAR complex related to memory formation in synapses: The possible roles of threonine 286 autophosphorylation of CaMKII in long term potentiation

He, Y., Kulasiri, D., & Samarasinghe, S. (2014) · Journal of Theoretical Biology · doi:10.1016/j.jtbi.2014.11.001 · Cited by 14

Dynamic impact of temporal context of Ca2+ signals on inhibitory synaptic plasticity

Kawaguchi, S., Nagasaki, N., & Hirano, T. (2011) · Scientific Reports · doi:10.1038/srep00143 · Cited by 15

Case Report: Developmental Delay and Acute Neuropsychiatric Episodes Associated With a de novo Mutation in the CAMK2B Gene (c.328G>A p.Glu110Lys)

Dwyer, B. K., Veenma, D. C. M., Chang, K., Schulman, H., & van Woerden, G. M. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.794008 · Cited by 15

Influence of the Prader-Willi syndrome imprinting center on the DNA methylation landscape in the mouse brain

Brant, J. O., Riva, A., Resnick, J. L., & Yang, T. P. (2014) · Epigenetics · doi:10.4161/15592294.2014.969667 · Cited by 15

Role of inhibitory autophosphorylation of calcium/calmodulin-dependent kinase II (αCAMKII) in persistent (>24h) hippocampal LTP and in LTD facilitated by novel object-place learning and recognition in mice

Goh, J. J., & Manahan‐Vaughan, D. (2014) · Behavioural Brain Research · doi:10.1016/j.bbr.2014.01.022 · Cited by 20

Autophosphorylation at Thr 286 of the α Calcium-Calmodulin Kinase II in LTP and Learning

Giese, K. P., Fedorov, N. B., Filipkowski, R. K., & Silva, A. J. (1998) · Science · doi:10.1126/science.279.5352.870 · Cited by 1,055

Autophosphorylation at Thr286 of the a calcium-calmodulin kinase

Giese, K.-P., Fedorov, N. B., Filipkowski, R. K., & Silva, A. J. (1998)

Autophosphorylation at Thr 286 of the calcium-calmodulin kinase II in LTP

Giese, K.-P., Fedorov, N. B., Filipkowski, R. K., & Silva, A. J. (1998)

Hippocampal Synaptic Metaplasticity Requires Inhibitory Autophosphorylation of Ca2+/Calmodulin-Dependent Kinase II

Zhang, L., Kirschstein, T., Sommersberg, B., Merkens, M., Manahan‐Vaughan, D., Elgersma, Y., & Beck, H. (2005) · Journal of Neuroscience · doi:10.1523/jneurosci.2086-05.2005 · Cited by 63