A mechanism for the Hebb and the anti-Hebb processes underlying learning and memory.

Theory for the development of neuron selectivity: orientation specificity and binocular interaction in visual cortex

Bienenstock, E., Cooper, L., & Munro, P. (1982) · The Journal of Neuroscience · doi:10.1523/jneurosci.02-01-00032.1982 · Cited by 2,896 · see citing works

NMDA-receptor activation increases cytoplasmic calcium concentration in cultured spinal cord neurones

MacDermott, A. B., Mayer, M. L., Westbrook, G. L., Smith, S. J., & Barker, J. L. (1986) · Nature · doi:10.1038/321519a0 · Cited by 1,835 · see citing works

Intracellular injections of EGTA block induction of hippocampal long-term potentiation

Lynch, G., Larson, J., Kelso, S., Barrionuevo, G., & Schottler, F. (1983) · Nature · doi:10.1038/305719a0 · Cited by 1,116 · see citing works

Noradrenergic enhancement of long-term potentiation at mossy fiber synapses in the hippocampus

Hopkins, W. F., & Johnston, D. (1988) · Journal of Neurophysiology · doi:10.1152/jn.1988.59.2.667 · Cited by 310 · see citing works

Synaptic Modifications in Cultured Hippocampal Neurons: Dependence on Spike Timing, Synaptic Strength, and Postsynaptic Cell Type

Bi, G.-Q., & Poo, M.-M. (1998) · The Journal of Neuroscience · doi:10.1523/jneurosci.18-24-10464.1998 · Cited by 4,744 · see citing works

AMPA Receptor Trafficking and Synaptic Plasticity

Malinow, R., & Malenka, R. C. (2002) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.25.112701.142758 · Cited by 2,588 · see citing works

Spike Timing–Dependent Plasticity: A Hebbian Learning Rule

Caporale, N., & Dan, Y. (2008) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.31.060407.125639 · Cited by 1,997 · see citing works

Homosynaptic long-term depression in area CA1 of hippocampus and effects of N-methyl-D-aspartate receptor blockade.

Dudek, S. M., & Bear, M. F. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.10.4363 · Cited by 1,708 · see citing works

NMDA receptor trafficking in synaptic plasticity and neuropsychiatric disorders

Lau, C. G., & Zukin, R. S. (2007) · Nature Reviews Neuroscience · doi:10.1038/nrn2153 · Cited by 1,159 · see citing works

NMDA receptor-dependent long-term potentiation and long-term depression (LTP/LTD).

Luscher, C., & Malenka, R. C. (2012) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a005710 · Cited by 1,110 · see citing works

AMPARs and Synaptic Plasticity: The Last 25 Years

Huganir, R. L., & Nicoll, R. A. (2013) · Neuron · doi:10.1016/j.neuron.2013.10.025 · Cited by 968 · see citing works

Regulation of AMPA receptor endocytosis by a signaling mechanism shared with LTD

Beattie, E. C., Carroll, R. C., Yu, X., Morishita, W., Yasuda, H., von Zastrow, M., & Malenka, R. C. (2000) · Nature Neuroscience · doi:10.1038/81823 · Cited by 745 · see citing works

Structure, Function, and Pharmacology of Glutamate Receptor Ion Channels

Hansen, K. B., Wollmuth, L. P., Bowie, D., Furukawa, H., Menniti, F. S., Sobolevsky, A. I., Swanson, G. T., Swanger, S. A., Greger, I. H., Nakagawa, T., et al. (2021) · Pharmacological Reviews · doi:10.1124/pharmrev.120.000131 · Cited by 686 · see citing works

Development and plasticity of cortical processing architectures

Singer, W. (1995) · Science · doi:10.1126/science.270.5237.758 · Cited by 669 · see citing works

Structure–function of the multifunctional Ca2+/calmodulin-dependent protein kinase II

HUDMON, A., & SCHULMAN, H. (2002) · Biochemical Journal · doi:10.1042/bj20020228 · Cited by 615 · see citing works

Protein phosphatase 1 is a molecular constraint on learning and memory

Genoux, D., Haditsch, U., Knobloch, M., Michalon, A., Storm, D., & Mansuy, I. M. (2002) · Nature · doi:10.1038/nature00928 · Cited by 472 · see citing works

The BCM theory of synapse modification at 30: interaction of theory with experiment

Cooper, L. N., & Bear, M. F. (2012) · Nature Reviews Neuroscience · doi:10.1038/nrn3353 · Cited by 395 · see citing works

D1/D5 dopamine receptor activation increases the magnitude of early long-term potentiation at CA1 hippocampal synapses

Otmakhova, N. A., & Lisman, J. E. (1996) · The Journal of Neuroscience · doi:10.1523/jneurosci.16-23-07478.1996 · Cited by 377 · see citing works

Biologically plausible error-driven learning using local activation differences: the generalized recirculation algorithm

O'Reilly, R. C. (1996) · Neural Computation · doi:10.1162/neco.1996.8.5.895 · Cited by 352 · see citing works

Homeostatic plasticity and NMDA receptor trafficking

Pérez-Otaño, I., & Ehlers, M. D. (2005) · Trends in Neurosciences · doi:10.1016/j.tins.2005.03.004 · Cited by 356 · see citing works

Long-term synaptic plasticity in hippocampal interneurons

Kullmann, D. M., & Lamsa, K. P. (2007) · Nature Reviews Neuroscience · doi:10.1038/nrn2207 · Cited by 340 · see citing works

Inhibitory Autophosphorylation of CaMKII Controls PSD Association, Plasticity, and Learning

Elgersma, Y., Fedorov, N. B., Ikonen, S., Choi, E. S., Elgersma, M., Carvalho, O. M., Giese, K. P., & Silva, A. J. (2002) · Neuron · doi:10.1016/s0896-6273(02)01007-3 · Cited by 290 · see citing works

Synaptic Signaling in Learning and Memory

Kennedy, M. B. (2016) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a016824 · Cited by 270 · see citing works

Bidirectional synaptic plasticity: from theory to reality

Bear, M. F. (2003) · Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences · doi:10.1098/rstb.2002.1255 · Cited by 260 · see citing works

Short- and long-term effects of cholinergic modulation on gamma oscillations and response synchronization in the visual cortex

Rodriguez, R., Kallenbach, U., Singer, W., & Munk, M. H. J. (2004) · The Journal of Neuroscience · doi:10.1523/jneurosci.1839-04.2004 · Cited by 246 · see citing works

Regulation of Synaptic Strength by Protein Phosphatase 1

Morishita, W., Connor, J. H., Xia, H., Quinlan, E. M., Shenolikar, S., & Malenka, R. C. (2001) · Neuron · doi:10.1016/s0896-6273(01)00554-2 · Cited by 227 · see citing works

GABA promotes the competitive selection of dendritic spines by controlling local Ca2+ signaling

Hayama, T., Noguchi, J., Watanabe, S., Takahashi, N., Hayashi-Takagi, A., Ellis-Davies, G. C. R., Matsuzaki, M., & Kasai, H. (2013) · Nature Neuroscience · doi:10.1038/nn.3496 · Cited by 193 · see citing works

Increased Threshold for Spike-Timing-Dependent Plasticity Is Caused by Unreliable Calcium Signaling in Mice Lacking Fragile X Gene Fmr1

Meredith, R. M., Holmgren, C. D., Weidum, M., Burnashev, N., & Mansvelder, H. D. (2007) · Neuron · doi:10.1016/j.neuron.2007.04.028 · Cited by 190 · see citing works

A three-step model for the synaptic recruitment of AMPA receptors

Opazo, P., & Choquet, D. (2011) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2010.08.014 · Cited by 190 · see citing works

An Associational Model of Birdsong Sensorimotor Learning I. Efference Copy and the Learning of Song Syllables

Troyer, T. W., & Doupe, A. J. (2000) · Journal of Neurophysiology · doi:10.1152/jn.2000.84.3.1204 · Cited by 145 · see citing works

Ca ²⁺ /calmodulin-dependent protein kinase II (CaMKII) is activated by calmodulin with two bound calciums

Shifman, J. M., Choi, M. H., Mihalas, S., Mayo, S. L., & Kennedy, M. B. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0606433103 · Cited by 143 · see citing works

Mechanisms Underlying the Rules for Associative Plasticity at Adult Human Neocortical Synapses

Verhoog, M. B., Goriounova, N. A., Obermayer, J., Stroeder, J., Hjorth, J. J. J., Testa-Silva, G., Baayen, J. C., de Kock, C. P. J., Meredith, R. M., & Mansvelder, H. D. (2013) · The Journal of Neuroscience · doi:10.1523/jneurosci.3158-13.2013 · Cited by 127 · see citing works

Neuroprotection by nicotine in mouse primary cortical cultures involves activation of calcineurin and L-type calcium channel inactivation

Stevens, T. R., Krueger, S. R., Fitzsimonds, R. M., & Picciotto, M. R. (2003) · The Journal of Neuroscience · doi:10.1523/jneurosci.23-31-10093.2003 · Cited by 119 · see citing works

A calcium-based plasticity model for predicting long-term potentiation and depression in the neocortex

Chindemi, G., Abdellah, M., Amsalem, O., Benavides-Piccione, R., Delattre, V., Doron, M., Ecker, A., Jaquier, A. T., King, J., Kumbhar, P., et al. (2022) · Nature Communications · doi:10.1038/s41467-022-30214-w · Cited by 102 · see citing works

Learning the invariance properties of complex cells from their responses to natural stimuli

Einhäuser, W., Kayser, C., König, P., & Körding, K. P. (2002) · European Journal of Neuroscience · doi:10.1046/j.0953-816x.2001.01885.x · Cited by 91 · see citing works

Hippocampal Synthesis of Sex Steroids and Corticosteroids: Essential for Modulation of Synaptic Plasticity

Hojo, Y., Higo, S., Kawato, S., Hatanaka, Y., Ooishi, Y., Murakami, G., Ishii, H., Komatsuzaki, Y., Ogiue-Ikeda, M., Mukai, H., et al. (2011) · Frontiers in Endocrinology · doi:10.3389/fendo.2011.00043 · Cited by 86 · see citing works

Temporal Sensitivity of Protein Kinase A Activation in Late-Phase Long Term Potentiation

Kim, M., Huang, T., Abel, T., & Blackwell, K. T. (2010) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1000691 · Cited by 72 · see citing works

Neurophysiological mechanisms of electroconvulsive therapy for depression

Kato, N. (2009) · Neuroscience Research · doi:10.1016/j.neures.2009.01.014 · Cited by 65 · see citing works

Learning Multisensory Integration and Coordinate Transformation via Density Estimation

Makin, J. G., Fellows, M. R., & Sabes, P. N. (2013) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1003035 · Cited by 53 · see citing works

Plasticity in the Hippocampus, Neurogenesis and Drugs of Abuse

Avchalumov, Y., & Mandyam, C. D. (2021) · Brain Sciences · doi:10.3390/brainsci11030404 · Cited by 49 · see citing works

MHC class I immune proteins are critical for hippocampus-dependent memory and gate NMDAR-dependent hippocampal long-term depression

Nelson, P. A., Sage, J. R., Wood, S. C., Davenport, C. M., Anagnostaras, S. G., & Boulanger, L. M. (2013) · Learning & Memory · doi:10.1101/lm.031351.113 · Cited by 49 · see citing works

The C‐terminal domains of the NMDA receptor: How intrinsically disordered tails affect signalling, plasticity and disease

Warnet, X. L., Bakke Krog, H., Sevillano‐Quispe, O. G., Poulsen, H., & Kjaergaard, M. (2021) · European Journal of Neuroscience · doi:10.1111/ejn.14842 · Cited by 50 · see citing works

Targeting metaplasticity mechanisms to promote sustained antidepressant actions

Brown, K. A., & Gould, T. D. (2024) · Molecular Psychiatry · doi:10.1038/s41380-023-02397-1 · Cited by 49 · see citing works

Voltage-Controlled Plasticity at GluR2-Deficient Synapses Onto Hippocampal Interneurons

Laezza, F., & Dingledine, R. (2004) · Journal of Neurophysiology · doi:10.1152/jn.00425.2004 · Cited by 47 · see citing works

The contribution of ion channels in input-output plasticity

Debanne, D., & Russier, M. (2019) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2019.107095 · Cited by 38 · see citing works

Erratum to “Consensus Paper: Probing Homeostatic Plasticity of Human Cortex With Non-invasive Transcranial Brain Stimulation”. Brain Stimulation 8 (2015) 442–454

Karabanov, A., Ziemann, U., Hamada, M., George, M. S., Quartarone, A., Classen, J., Massimini, M., Rothwell, J., & Siebner, H. R. (2015) · Brain Stimulation · doi:10.1016/j.brs.2015.06.016 · Cited by 5 · see citing works