Probiotics: towards demonstrating efficacy
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Probiotic efficacy is well established to be strain-, dose-, and formulation-specific, with clinical benefit demonstrated only for selected organisms and indications rather than for probiotics as a class.
“Probiotic efficacy is well established to be strain-, dose-, and formulation-specific, with clinical benefit demonstrated only for selected organisms and indications rather than for probiotics as a class.52-54”
From Safety and efficacy concerns in Indian probiotics: Insights from whole-genome sequencing and <i>in vitro</i> assessment (2026) · cites this paper as [52]
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- Authors
- Mattila-Sandholm, T., Blum, S., Collins, J. K., Crittenden, R., de Vos, W., Dunne, C., Fondén, R., Grenov, G., Isolauri, E., Kiely, B., Marteau, P., Morelli, L., Ouwehand, A., Reniero, R., Saarela, M., Salminen, S., Saxelin, M., Schiffrin, E., Shanahan, F., Vaughan, E., & von Wright, A.
- Affiliations
- Nestec (Switzerland) (CH)
- University College Cork (IE)
- VTT Technical Research Centre of Finland (FI)
- Chr. Hansen (Denmark) (DK)
- Hôpital Européen Georges-Pompidou (FR)
- Turku University Hospital (FI)
- Università Cattolica del Sacro Cuore (IT)
- University of Turku (FI)
- Valio (Finland) (FI)
- Wageningen University & Research (NL)
- ORCID
- Venue
- Trends in Food Science & Technology
- Publisher
- Elsevier BV
- Published
- 1999-12
- Volume
- 10
- Issue
- 12
- Pages
- 393-399
- ISSN
- 0924-2244 (ISSN-L)
- OpenAlex
- W1995169662
- Cited by
- 110
- References
- 32
- Citations by year
- 2026: 1 · 2023: 1 · 2022: 2 · 2021: 1 · 2019: 5 · 2017: 2 · 2016: 3 · 2015: 2 · 2014: 7 · 2013: 5 · 2012: 8
- FWCI
- 14.77
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Trends in Food Science & Technology (publishedVersion)
- Funders
- European Commission
- Valio
- Topics
- Life Sciences › Agricultural and Biological Sciences › Food Science › Probiotics and Fermented Foods
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
- Health Sciences › Nursing › Nutrition and Dietetics › Infant Nutrition and Health
- Keywords
- probiotics, probiotic efficacy, gut microbiota, immunomodulation, atopic dermatitis, infant food allergy, inflammatory bowel disease, infections in the elderly, probiotic strain selection
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