The culture of neurons on silicon
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Silicon is bioinert as a material, permitting cell growth and remaining stable for long periods of implantation without causing adverse tissue reactions.
“Silicon is bioinert as a material, permitting cell growth (Bayliss et al., 1999) and remaining stable for long periods of implantation without causing adverse tissue reactions (Shin et al., 2019).”
From Foreign Body Reaction to Implanted Biomaterials and Its Impact in Nerve Neuroprosthetics (2021) · cites this paper as Bayliss et al., 1999
Cites
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Foreign Body Reaction to Implanted Biomaterials and Its Impact in Nerve Neuroprosthetics
Carnicer-Lombarte, A., Chen, S.-T., Malliaras, G. G., & Barone, D. G. (2021) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2021.622524 · Cited by 454 · see citing works
“While as a material silicon is chemically inert and biocompatible, permitting cell growth and not causing particular adverse reactions in tissue over long implantation periods (Bayliss et al., 1999; Shin et al., 2019), its high stiffness leads to poor tissue compatibility when applied to such an invasive format.”
Background
- Authors
- Bayliss, S. C., Buckberry, L. D., Fletcher, I., & Tobin, M. J.
- Affiliations
- De Montfort University (GB)
- Daresbury Laboratory (GB)
- Corresponding author
- Bayliss, S.C
- Venue
- Sensors and Actuators A Physical
- Publisher
- Elsevier BV
- Published
- 1999-04
- Volume
- 74
- Issue
- 1-3
- Pages
- 139-142
- ISSN
- 0924-4247 (ISSN-L)
- OpenAlex
- W2008301276
- Cited by
- 93
- References
- 23
- Citations by year
- 2025: 2 · 2024: 2 · 2021: 2 · 2020: 1 · 2019: 1 · 2018: 2 · 2017: 2 · 2016: 2 · 2015: 4 · 2014: 4 · 2013: 5 · 2012: 3
- FWCI
- 1.20
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Sensors and Actuators A Physical (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neural Engineering
- Physical Sciences › Materials Science › Materials Chemistry › Silicon Nanostructures and Photoluminescence
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Cellular Mechanics and Interactions
- Keywords
- neuronal cell culture, porous silicon, polycrystalline silicon, silicon nanostructures, cell adhesion, cell viability, silicon substrate
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
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