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Compliance in asthma
Open accessAbstract
Low rates of compliance with medication pose a major challenge to the effective management of most chronic diseases, including asthma. The high medical and social costs of non-compliance, and the apparent lack of effective methods for dealing with it, has stimulated renewed interest in this complex issue. Two broad categories of non-compliance have been identified, namely unintentional (or 'accidental') and intentional (or 'deliberate'). Unintentional non-compliance may result from poor doctor-patient communication or a lack of ability to follow advice. Intentional non-compliance occurs when the patient knows what is required but decides not to follow this to some degree. Healthcare professionals need to be aware of the various issues affecting compliance in all patients. The reasons for non-compliance are many and varied, and include factors such as complexity of the treatment regimen, administration route, patient beliefs about therapy and other psychological factors. Improvement in patient compliance with therapy will require better doctor-patient communication, improved patient education, the tailoring of therapy to the individual and possible novel strategies such as offering feedback to the patients on their level of compliance.
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“Concerns about asthma medicines and side-effects are known to add to the burden of living with asthma and lower levels of medication adherence [35].”
From A randomised controlled feasibility trial of Group Cognitive Behavioural Therapy for people with severe asthma (2017) · cites this paper as [35]
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Citations
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Nizami, T. A., & Mash, R. J. (2005) · PubMed · Cited by 5
Symptoms of Depression and Inhaler Adherence Among Adolescents With Asthma: Is There an Association?
Setty, N. K. H., Kumar, P., Sharma, P. P., Goel, A. D., Aneja, J., Gupta, M. K., Raghav, P. R., & Dutt, N. (2025) · Pediatric Pulmonology · doi:10.1002/ppul.71098 · Cited by 4
Cumplimiento terapéutico en asma: ¿un problema de gran magnitud?
de Antioquia, U., Rodriguez, A. P., Morales-Múnera, O., de Antioquia, U., Contreras-Ortiz, J. O., de Antioquia, U., Salazar-Blanco, O. F., & de Antioquia, U. (2015) · IATREIA · doi:10.17533/udea.iatreia.v28n4a05 · Cited by 4
“El cuestionario original consta de 30 preguntas que comprenden ítems sobre creencias en salud, experiencias y comportamiento; el cuestionario modificado para asma cuenta con 10 preguntas (MARS-10) (18,21,23-25).”
BackgroundDębowski, T., Marko, M., Rogala, B., Majak, P., & Pawliczak, R. (2023) · Pulmonary Pharmacology & Therapeutics · doi:10.1016/j.pupt.2023.102272 · Cited by 4
Patients' knowledge about treatment for opiate dependence
Alves, P., & WINSTOCK, A. R. (2011) · The Psychiatrist · doi:10.1192/pb.bp.111.034546 · Cited by 4
Bielory, L., Picone, F. J., RABINOWITZ, P., Rossoff, L. J., Winder, J. A., Incaudo, G. A., Wu, J., & Newman, K. B. (2000) · Clinical Drug Investigation · doi:10.2165/00044011-200019020-00002 · Cited by 4
“[3,5] Currently, most inhaled corticosteroids available in the USAare administered in multidose regimens ranging from 2 to 4 times daily.”
BackgroundPatient responses to inhaler advice given by community pharmacies: The importance of meaningfulness
Kaae, S. S., Aarup, K. H. F., & Sporrong, S. K. (2016) · Research in Social and Administrative Pharmacy · doi:10.1016/j.sapharm.2016.03.006 · Cited by 5
“Cochrane et al likewise reported that an incorrect device technique is often non-intentional.(24) This demonstrates the importance of pharmacy providing such type of counseling.”
BackgroundThe JeffCare Preceptor Model for Asthma: A Primary Care Physician Tutorial Training Model
Lenow, J. L., Bales, R. W., & Smullens, S. N. (2003) · Disease Management · doi:10.1089/109350703321530864 · Cited by 4
“17 In addressing the special needs of our inner city population, where asthma management can be most challenging, recognition of the fact that there is significant underuse of ICSs (despite admonitions from the National Institutes of Health asthma guidelines) and a greater need to impact the…”
Combination Therapy for Asthma
Farber, H. J., & Glauber, J. H. (2006) · Disease Management & Health Outcomes · doi:10.2165/00115677-200614060-00005 · Cited by 4
Ţîrcă, S. M., Ciontea, M. S., Vlad, E., & Mihaltan, F. D. (2021) · Internal Medicine · doi:10.2478/inmed-2021-0155 · Cited by 3
Huang, Y.-W., Miao, F., Dai, Y., Chang, C., Zhang, X., & Dai, H. (2023) · Frontiers in Public Health · doi:10.3389/fpubh.2023.1065311 · Cited by 3
“However, studies indicate that 40%−60% of patients with asthma were non-adherent to their medication (46, 47).”
BackgroundDrugs for the treatment of asthma and COPD
Barnes, P. J. (2005) · Birkhäuser Basel eBooks · doi:10.1007/3-7643-7408-x_19 · Cited by 3
Chamnan, P., Boonlert, K., Pasi, W., Yodsiri, S., Pong-on, S., Khansa, B., & Yongkulwanitchanan, P. (2010) · PubMed · Cited by 3
Budesonide/formoterol for maintenance and reliever therapy: new quality in asthma management
Kuna, P., & Kuprys-Lipinska, I. R. (2008) · Therapy · doi:10.2217/14750708.5.4.495 · Cited by 3
“Complicated dosing schemes decrease compliance, while lessfrequent dosing improves it [65].”
BackgroundAderência ao tratamento da asma
Gonçalves, A. F. D. S., & Lopes, D. J. A. M. (2010) · Revista Portuguesa de Pneumologia · doi:10.1016/s2173-5115(10)70022-1 · Cited by 3
Health psychology interventions to improve adherence to maintenance therapies in asthma
Normansell, R., Chan, A. H. Y., Katzer, C. B., Kew, K. M., Mes, M. A., Newby, C., Chauhan, A., Taylor, S. J., Pinnock, H., Sheikh, A., et al. (2018) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd013147 · Cited by 3
“…with non-adherence include: treatment complexity; cost; administration route; patient beliefs about asthma or the treatment; lower socioeconomic status; inclusion in a minority ethnic group and fewer years of education (Bender 2005; Bårnes 2015; Clark 1999; Cochrane 1999; Horne 1999; Horne 2002).”
BackgroundMethodAderência ao tratamento da asma
Gonçalves, A. F. D. S. (2010) · Revista Portuguesa de Pneumologia · doi:10.1016/s0873-2159(15)30010-6 · Cited by 3
New insights in mite immunotherapy – sublingual tablets
Creticos, P. S. (2021) · Current Opinion in Allergy and Clinical Immunology · doi:10.1097/aci.0000000000000785 · Cited by 3
“Indeed, even in asthma management, 40% of patients stop using their daily controller medications within 6 months [55,56].”
BackgroundImpacts of a PBM-Based Disease Management Program on Asthma Medication Use
Feifer, R. A. (2001) · Journal of Managed Care Pharmacy · doi:10.18553/jmcp.2001.7.6.460 · Cited by 3
Metadata
- Authors
- Cochrane, G. M., Horne, R., & Chanez, P.
- Affiliations
- St Thomas' Hospital (GB)
- University of Brighton (GB)
- Hôpital Arnaud de Villeneuve (FR)
- ORCID
- Venue
- Respiratory Medicine
- Publisher
- Elsevier BV
- Published
- 1999-11
- Volume
- 93
- Issue
- 11
- Pages
- 763-769
- ISSN
- 0954-6111 (ISSN-L)
- OpenAlex
- W2016277634
- Cited by
- 246
- References
- 47
- Citations by year
- 2025: 2 · 2024: 2 · 2023: 6 · 2022: 2 · 2021: 4 · 2020: 3 · 2019: 3 · 2018: 5 · 2017: 5 · 2016: 8 · 2015: 2 · 2014: 12 · 2013: 8 · 2012: 12
- FWCI
- 3.29
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Respiratory Medicine (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Family Practice › Medication Adherence and Compliance
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Asthma and respiratory diseases
- Health Sciences › Health Professions › Pharmacy › Pharmacy and Medical Practices
- Keywords
- medication adherence, asthma, non-compliance, physician-patient communication, patient education, psychological factors
- MeSH terms
- Asthma, Drug Administration Schedule, Humans, Patient Compliance, Treatment Refusal, Anti-Asthmatic Agents
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