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The role of phosphoinositides in membrane transport

Simonsen, Anne, Wurmser, Andrew E, Emr, Scott D, Stenmark, Harald·2001·Current Opinion in Cell Biology
DOI 10.1016/s0955-0674(00)00240-4
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Abstract

Phosphoinositides serve as intrinsic membrane signals that regulate intracellular membrane trafficking. Recently, phosphoinositides have been found to direct the localization and activity of effector proteins containing consensus sequence motifs such as FYVE, PH and ENTH domains. In addition, recent results show that regulated synthesis and turnover of phosphoinositides by membrane-associated phosphoinoside kinases and phosphatases spatially restrict the location of effectors critical for cellular transport processes, such as clathrin-mediated endocytosis, autophagy, phagocytosis, macropinocytosis and biosynthetic trafficking.

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Research works printed but not linked: 57

  1. Toker, 1997, Signalling through the lipid products of phosphoinositide-3-OH kinase, Nature, 387, 673, 10.1038/42648 · DOI
  2. Schu, 1993, Phosphatidylinositol 3-kinase encoded by yeast VPS34 gene essential for protein sorting, Science, 260, 88, 10.1126/science.8385367 · DOI · Paper page
  3. Jost, 1998, Phosphatidylinositol-4,5-bisphosphate is required for endocytic coated vesicle formation, Curr Biol, 8, 1399, 10.1016/S0960-9822(98)00022-0 · DOI
  4. Kay, 1999, Identification of a novel domain shared by putative components of the endocytic and cytoskeletal machinery, Protein Sci, 8, 435, 10.1110/ps.8.2.435 · DOI
  5. Itoh, 2001, Role of the ENTH domain in phosphatidylinositol-4,5-bisphosphate binding and endocytosis, Science, 291, 1047, 10.1126/science.291.5506.1047 · DOI · Paper page
  6. Ford, 2001, Simultaneous binding of PtdIns(4,5)P2 and clathrin by AP180 in the nucleation of clathrin lattices on membranes role of the ENTH domain in phosphatidylinositol-4,5-bisphosphate binding and endocytosis, Science, 291, 1051, 10.1126/science.291.5506.1051 · DOI · Paper page
  7. Mao, 2001, A novel all helix fold of the AP180 amino-terminal domain for phosphoinositide binding and clathrin assembly in synaptic vesicle endocytosis, Cell, 104, 433, 10.1016/S0092-8674(01)00230-6 · DOI
  8. Hill, 2001, The role of dynamin and its binding partners in coated pit invagination and scission, J Cell Biol, 152, 309, 10.1083/jcb.152.2.309 · DOI
  9. Marks, 2001, GTPase activity of dynamin and resulting conformation change are essential for endocytosis, Nature, 410, 231, 10.1038/35065645 · DOI
  10. Burger, 2000, Dynamin is membrane-active: lipid insertion Is induced by phosphoinositides and phosphatidic acid, Biochemistry, 39, 12485, 10.1021/bi000971r · DOI
  11. Schmidt, 1999, Endophilin I mediates synaptic vesicle formation by transfer of arachidonate to lysophosphatidic acid, Nature, 401, 133, 10.1038/43613 · DOI
  12. Gad, 2000, Fission and uncoating of synaptic clathrin-coated vesicles are perturbed by disruption of interactions with the SH3 domain of endophilin, Neuron, 27, 301, 10.1016/S0896-6273(00)00038-6 · DOI
  13. Cremona, 1999, Essential role of phosphoinositide metabolism in synaptic vesicle recycling, Cell, 99, 179, 10.1016/S0092-8674(00)81649-9 · DOI
  14. Harris, 2000, Mutations in synaptojanin disrupt synaptic vesicle recycling, J Cell Biol, 150, 589, 10.1083/jcb.150.3.589 · DOI
  15. Haffner, 2000, Direct interaction of the 170 kDa isoform of synaptojanin 1 with clathrin and with the clathrin adaptor AP-2, Curr Biol, 10, 471, 10.1016/S0960-9822(00)00446-2 · DOI
  16. Malecz, 2000, Synaptojanin 2, a novel rac1 effector that regulates clathrin-mediated endocytosis, Curr Biol, 10, 1383, 10.1016/S0960-9822(00)00778-8 · DOI
  17. Chung, 1997, Synaptojanin inhibition of phospholipase D activity by hydrolysis of phosphatidylinositol 4,5-bisphosphate, J Biol Chem, 272, 15980, 10.1074/jbc.272.25.15980 · DOI
  18. Lee, 1997, Inhibition of phospholipase D by clathrin assembly protein 3 (AP3), J Biol Chem, 272, 15986, 10.1074/jbc.272.25.15986 · DOI
  19. Lee, 2000, Inhibition of phospholipase D by amphiphysins, J Biol Chem, 275, 18751, 10.1074/jbc.M001695200 · DOI
  20. Wurmser, 1999, Phosphoinositide 3-kinases and their FYVE domain-containing effectors as regulators of vacuolar/lysosomal membrane trafficking pathways, J Biol Chem, 274, 9129, 10.1074/jbc.274.14.9129 · DOI
  21. Gillooly, 2001, Cellular functions of phosphatidylinositol 3-phosphate and FYVE domain proteins, Biochem J, 355, 249, 10.1042/0264-6021:3550249 · DOI
  22. Kutateladze, 2001, Structural mechanism of endosome docking by the FYVE domain, Science, 291, 1793, 10.1126/science.291.5509.1793 · DOI
  23. Gillooly, 2000, Localization of phosphatidylinositol 3-phosphate in yeast and mammalian cells, EMBO J, 19, 4577, 10.1093/emboj/19.17.4577 · DOI · Paper page
  24. Simonsen, 1998, EEA1 links PI(3)K function to Rab5 regulation of endosome fusion, Nature, 394, 494, 10.1038/28879 · DOI · Paper page
  25. Rubino, 2000, Selective membrane recruitment of EEA1 suggests a role in directional transport of clathrin-coated vesicles to early endosomes, J Biol Chem, 275, 3745, 10.1074/jbc.275.6.3745 · DOI
  26. Kim, 2001, Trafficking of phosphatidylinositol 3-phosphate from the trans-Golgi network to the lumen of the central vacuole in plant cells, Plant Cell, 13, 287, 10.1105/tpc.13.2.287 · DOI
  27. Wurmser, 1998, Phosphoinositide signaling and turnover: PtdIns(3)P, a regulator of membrane traffic, is transported to the vacuole and degraded by a process that requires lumenal vacuolar hydrolase activities, EMBO J, 17, 4930, 10.1093/emboj/17.17.4930 · DOI
  28. Peterson, 1999, Vac1p coordinates Rab and phosphatidylinositol 3-kinase signaling in Vps45p-dependent vesicle docking/fusion at the endosome, Curr Biol, 9, 159, 10.1016/S0960-9822(99)80071-2 · DOI
  29. Nielsen, 2000, Rabenosyn-5, a novel rab5 effector, is complexed with hVPS45 and recruited to endosomes through a FYVE finger domain, J Cell Biol, 151, 601, 10.1083/jcb.151.3.601 · DOI
  30. Cormont, 2001, A FYVE-finger-containing protein, Rabip4, is a Rab4 effector involved in early endosomal traffic, Proc Natl Acad Sci USA, 98, 1637, 10.1073/pnas.031586998 · DOI
  31. Blondeau, 2000, Myotubularin, a phosphatase deficient in myotubular myopathy, acts on phosphatidylinositol 3-kinase and phosphatidylinositol 3-phosphate pathway, Hum Mol Genet, 9, 2223, 10.1093/oxfordjournals.hmg.a018913 · DOI
  32. Taylor, 2000, Myotubularin, a protein tyrosine phosphatase mutated in myotubular myopathy, dephosphorylates the lipid second messenger, phosphatidylinositol 3-phosphate, Proc Natl Acad Sci USA, 97, 8910, 10.1073/pnas.160255697 · DOI
  33. Zhao, 2000, FYVE-DSP1, a dual-specificity protein phosphatase containing an FYVE domain, Biochem Biophys Res Commun, 270, 222, 10.1006/bbrc.2000.2417 · DOI
  34. Shisheva, 2000, Localization and insulin-regulated relocation of 5′-phosphoinositide kinase PIKfyve in 3T3-L1 adipocytes, J Biol Chem, 276, 11859, 10.1074/jbc.M008437200 · DOI
  35. Yamamoto, 1995, Novel PI(4)P 5-kinase homologue, Fab1p, essential for normal vacuole function and morphology in yeast, Mol Biol Cell, 6, 525, 10.1091/mbc.6.5.525 · DOI
  36. Odorizzi, 1998, Fab1p PtdIns(3)P 5-kinase function essential for protein sorting in the multivesicular body, Cell, 95, 847, 10.1016/S0092-8674(00)81707-9 · DOI · Paper page
  37. Mayer, 2000, Phosphatidylinositol 4,5-bisphosphate regulates two steps of homotypic vacuole fusion, Mol Biol Cell, 11, 807, 10.1091/mbc.11.3.807 · DOI
  38. Gaidarov, 2001, The class II phosphoinositide 3-kinase C2alpha is activated by clathrin and regulates clathrin-mediated membrane trafficking, Mol Cell, 7, 443, 10.1016/S1097-2765(01)00191-5 · DOI
  39. Domin, 2000, The class II phosphoinositide 3-kinase PI3K-C2alpha is concentrated in the trans-Golgi network and present in clathrin-coated vesicles, J Biol Chem, 275, 11943, 10.1074/jbc.275.16.11943 · DOI
  40. Arcaro, 2000, Class II phosphoinositide 3-kinases are downstream targets of activated polypeptide growth factor receptors, Mol Cell Biol, 20, 3817, 10.1128/MCB.20.11.3817-3830.2000 · DOI
  41. Amyere, 2000, Constitutive macropinocytosis in oncogene-transformed fibroblasts depends on sequential permanent activation of phosphoinositide 3-kinase and phospholipase C, Mol Biol Cell, 11, 3453, 10.1091/mbc.11.10.3453 · DOI
  42. Gold, 2000, Amphiphysin IIm, a novel amphiphysin II isoform, is required for macrophage phagocytosis, Immunity, 12, 285, 10.1016/S1074-7613(00)80181-8 · DOI
  43. Carpenter, 1997, Signal transduction pathways involving the small G proteins rac and Cdc42 and phosphoinositide kinases, Adv Enzyme Regul, 37, 377, 10.1016/S0065-2571(96)00005-2 · DOI
  44. Tolias, 2000, Type I alpha phosphatidylinositol-4-phosphate 5-kinase mediates Rac-dependent actin assembly, Curr Biol, 10, 153, 10.1016/S0960-9822(00)00315-8 · DOI
  45. Rozelle, 2000, Phosphatidylinositol 4,5-bisphosphate induces actin-based movement of raft-enriched vesicles through WASP-Arp2/3. movement of raft-enriched vesicles through WASP-Arp2/3, Curr Biol, 10, 311, 10.1016/S0960-9822(00)00384-5 · DOI
  46. Klionsky, 2000, Autophagy as a regulated pathway of cellular degradation, Science, 290, 1717, 10.1126/science.290.5497.1717 · DOI
  47. Klionsky, 1999, Vacuolar import of proteins and organelles from the cytoplasm, Annu Rev Cell Dev Biol, 15, 1, 10.1146/annurev.cellbio.15.1.1 · DOI
  48. Darsow, 1997, A multispecificity syntaxin homologue, Vam3p, essential for autophagic and biosynthetic protein transport to the vacuole, J Cell Biol, 138, 517, 10.1083/jcb.138.3.517 · DOI
  49. Kiel, 1999, The Hansenula polymorpha PDD1 gene product, essential for the selective degradation of peroxisomes, is a homologue of Saccharomyces cerevisiae Vps34p, Yeast, 15, 741, 10.1002/(SICI)1097-0061(19990630)15:9<741::AID-YEA416>3.0.CO;2-O · DOI
  50. Petiot, 2000, Distinct classes of phosphatidylinositol 3′-kinases are involved in signaling pathways that control macroautophagy in HT-29 cells, J Biol Chem, 275, 992, 10.1074/jbc.275.2.992 · DOI
  51. Desrivieres, 1998, MSS4, a phosphatidylinositol-4-phosphate 5-kinase required for organization of the actin cytoskeleton in Saccharomyces cerevisiae, J Biol Chem, 273, 15787, 10.1074/jbc.273.25.15787 · DOI
  52. Hama, 1999, Direct involvement of phosphatidylinositol 4-phosphate in secretion in the yeast Saccharomyces cerevisiae, J Biol Chem, 274, 34294, 10.1074/jbc.274.48.34294 · DOI
  53. Walch-Solimena, 1999, The yeast phosphatidylinositol-4-OH kinase pik1 regulates secretion at the Golgi, Nat Cell Biol, 1, 523, 10.1038/70319 · DOI
  54. Audhya, 2000, Distinct roles for the yeast phosphatidylinositol 4-kinases, stt4p and pik1p, in secretion, cell growth, and organelle membrane dynamics, Mol Biol Cell, 11, 2673, 10.1091/mbc.11.8.2673 · DOI
  55. Trotter, 1998, A genetic screen for aminophospholipid transport mutants identifies the phosphatidylinositol 4-kinase, STT4p, as an essential component in phosphatidylserine metabolism, J Biol Chem, 273, 13189, 10.1074/jbc.273.21.13189 · DOI
  56. Hendricks, 1999, Yeast homologue of neuronal frequenin is a regulator of phosphatidylinositol-4-OH kinase, Nat Cell Biol, 1, 234, 10.1038/12058 · DOI
  57. Godi, 1999, ARF mediates recruitment of PtdIns-4-OH kinase-beta and stimulates synthesis of PtdIns(4,5)P2 on the Golgi complex, Nat Cell Biol, 1, 280, 10.1038/12993 · DOI

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Metadata

Authors
Simonsen, A., Wurmser, A. E., Emr, S. D., & Stenmark, H.
Venue
Current Opinion in Cell Biology
Publisher
Elsevier BV
Published
2001-08
Volume
13
Issue
4
Pages
485-492
ISSN
0955-0674
DOI
10.1016/s0955-0674(00)00240-4
Cited by
407
References
3
Language
en
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)

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