Adhesion events in angiogenesis

Endostatin: an endogenous inhibitor of angiogenesis and tumor growth

O'Reilly, M. S., Boehm, T., Shing, Y., Fukai, N., Vasios, G., Lane, W. S., Flynn, E., Birkhead, J. R., Olsen, B. R., & Folkman, J. (1997) · Cell · doi:10.1016/s0092-8674(00)81848-6 · Cited by 4,486 · see citing works

Integrin signaling

Giancotti, F. G., & Ruoslahti, E. (1999) · Science · doi:10.1126/science.285.5430.1028 · Cited by 3,869 · see citing works

Angiostatin: A novel angiogenesis inhibitor that mediates the suppression of metastases by a lewis lung carcinoma

OʼReilly, M. (1994) · Cell · doi:10.1016/0092-8674(94)90200-3 · Cited by 3,344 · see citing works

Integrin αvβ3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels

Brooks, P. C., Montgomery, A. M. P., Rosenfeld, M., Reisfeld, R. A., Hu, T., Klier, G., & Cheresh, D. A. (1994) · Cell · doi:10.1016/0092-8674(94)90007-8 · Cited by 2,262 · see citing works

Integrins: Emerging Paradigms of Signal Transduction

Schwartz, M. A., Schaller, M. D., & Ginsberg, M. H. (1995) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cb.11.110195.003001 · Cited by 1,596 · see citing works

Localization of Matrix Metalloproteinase MMP-2 to the Surface of Invasive Cells by Interaction with Integrin αvβ3

Brooks, P. C., Strömblad, S., Sanders, L. C., Schalscha, T. V., Aimes, R. T., Stetler‐Stevenson, W. G., Quigley, J. P., & Cheresh, D. A. (1996) · Cell · doi:10.1016/s0092-8674(00)81235-0 · Cited by 1,552 · see citing works

The extracellular matrix as a cell survival factor.

Meredith, J. E., Fazeli, B., & Schwartz, M. A. (1993) · Molecular Biology of the Cell · doi:10.1091/mbc.4.9.953 · Cited by 1,540 · see citing works

Definition of Two Angiogenic Pathways by Distinct α v Integrins

Friedlander, M., Brooks, P. C., Shaffer, R. W., Kincaid, C. M., Varner, J. A., & Cheresh, D. A. (1995) · Science · doi:10.1126/science.270.5241.1500 · Cited by 1,310 · see citing works

Flt-1 lacking the tyrosine kinase domain is sufficient for normal development and angiogenesis in mice

Hiratsuka, S., Minowa, O., Kuno, J., Noda, T., & Shibuya, M. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.16.9349 · Cited by 1,063 · see citing works

A tumor suppressor-dependent inhibitor of angiogenesis is immunologically and functionally indistinguishable from a fragment of thrombospondin.

Good, D. J., Polverini, P. J., Rastinejad, F., Beau, M. M. L., Lemons, R. S., Frazier, W. A., & Bouck, N. (1990) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.87.17.6624 · Cited by 1,051 · see citing works

Signal Transduction and Signal Modulation by Cell Adhesion Receptors: The Role of Integrins, Cadherins, Immunoglobulin-Cell Adhesion Molecules, and Selectins

Aplin, A. E., Howe, A. K., Alahari, S. K., & Juliano, R. L. (1998) · Pharmacological Reviews · doi:10.1016/s0031-6997(24)01359-0 · Cited by 847 · see citing works

Selective Requirement for Src Kinases during VEGF-Induced Angiogenesis and Vascular Permeability

Eliceiri, B. P., Paul, R., Schwartzberg, P. L., Hood, J. D., Leng, J., & Cheresh, D. A. (1999) · Molecular Cell · doi:10.1016/s1097-2765(00)80221-x · Cited by 814 · see citing works

Integrins can collaborate with growth factors for phosphorylation of receptor tyrosine kinases and MAP kinase activation: roles of integrin aggregation and occupancy of receptors.

Miyamoto, S., Teramoto, H., Gutkind, J. S., & Yamada, K. M. (1996) · The Journal of Cell Biology · doi:10.1083/jcb.135.6.1633 · Cited by 758 · see citing works

β3-integrin–deficient mice are a model for Glanzmann thrombasthenia showing placental defects and reduced survival

Hodivala‐Dilke, K., McHugh, K. P., Tsakiris, D. Α., Rayburn, H., Crowley, D. G., Ullman-Culleré, M., Ross, F. P., Coller, B. S., Teitelbaum, S. L., & Hynes, R. O. (1999) · Journal of Clinical Investigation · doi:10.1172/jci5487 · Cited by 741 · see citing works

Embryonic mesodermal defects in α5 integrin-deficient mice

Yang, J. T., Rayburn, H., & Hynes, R. O. (1993) · Development · doi:10.1242/dev.119.4.1093 · Cited by 691 · see citing works

Role of αvβ3 integrin in the activation of vascular endothelial growth factor receptor‐2

Soldi, R., Mitola, S. M. F., Strasly, M., Defilippi, P., Tarone, G., & Bussolino, F. (1999) · The EMBO Journal · doi:10.1093/emboj/18.4.882 · Cited by 627 · see citing works

Stimulation of endothelial cell migration by vascular permeability factor/vascular endothelial growth factor through cooperative mechanisms involving the alphavbeta3 integrin, osteopontin, and thrombin.

Senger, D. R., Ledbetter, S. R., Claffey, K. P., Papadopoulos-Sergiou, A., Peruzzi, C. A., & Detmar, M. J. (1996) · Europe PMC (PubMed Central) · Cited by 548 · see citing works

Angiostatin binds ATP synthase on the surface of human endothelial cells

Moser, T. L., Stack, M. S., Asplin, I. R., Enghild, J. J., Højrup, P., Everitt, L., Hubchak, S. C., Schnaper, H. W., & Pizzo, S. V. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.6.2811 · Cited by 526 · see citing works

Angiogenesis promoted by vascular endothelial growth factor: Regulation through α 1 β 1 and α 2 β 1 integrins

Senger, D. R., Claffey, K. P., Benes, J. E., Perruzzi, C. A., Papadopoulos-Sergiou, A., & Detmar, M. J. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.25.13612 · Cited by 522 · see citing works

Inhibition of anchorage-dependent cell spreading triggers apoptosis in cultured human endothelial cells.

Re, F., Zanetti, A., Sironi, M., Polentarutti, N., Lanfrancone, L., Dejana, E., & Colotta, F. (1994) · The Journal of Cell Biology · doi:10.1083/jcb.127.2.537 · Cited by 499 · see citing works

αvβ3 integrin associates with activated insulin and PDGFβ receptors and potentiates the biological activity of PDGF

Schneller, M., Vuori, K., & Ruoslahti, E. (1997) · The EMBO Journal · doi:10.1093/emboj/16.18.5600 · Cited by 492 · see citing works

Canstatin, a Novel Matrix-derived Inhibitor of Angiogenesis and Tumor Growth

Kamphaus, G. D., Colorado, P. C., Panka, D. J., Hopfer, H., Ramchandran, R., de la Torre, A., Maeshima, Y., Mier, J. W., Sukhatme, V. P., & Kalluri, R. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.275.2.1209 · Cited by 470 · see citing works

Interaction of endostatin with integrins implicated in angiogenesis

Rehn, M., Veikkola, T., Kukk, E., Nakamura, H., Ilmonen, M., Lombardo, C. R., Pihlajaniemi, T. A., Alitalo, K. K., & Vuori, K. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.98.3.1024 · Cited by 455 · see citing works

Endostatin inhibits VEGF‐induced endothelial cell migration and tumor growth independently of zinc binding

Yamaguchi, N., Anand‐Apte, B., Lee, M., Sasaki, T., Fukai, N., Shapiro, R., Que, I., Lowik, C., Timpl, R., & Olsen, B. R. (1999) · The EMBO Journal · doi:10.1093/emboj/18.16.4414 · Cited by 440 · see citing works

A Mechanism for Modulation of Cellular Responses to VEGF Activation of the Integrins

Byzova, T. V. (2000) · Molecular Cell · doi:10.1016/s1097-2765(00)00083-6 · Cited by 439 · see citing works

Cell adhesion: old and new questions

Hynes, R. O. (1999) · Trends in Cell Biology · doi:10.1016/s0962-8924(99)01667-0 · Cited by 427 · see citing works

Anti-angiogenic cues from vascular basement membrane collagen.

Colorado, P. C., Torre, A., Kamphaus, G. D., Maeshima, Y., Hopfer, H., Takahashi, K., Volk, R., Zamborsky, E. D., Herman, S., Sarkar, P. K., et al. (2000) · PubMed · Cited by 421 · see citing works

The cell biology of thrombospondin-1

Chen, H., Herndon, M. E., & Lawler, J. (2000) · Matrix Biology · doi:10.1016/s0945-053x(00)00107-4 · Cited by 393 · see citing works

Targeted antiangiogenic therapy for cancer using Vitaxin: a humanized monoclonal antibody to the integrin alphavbeta3.

Gutheil, J. C., Campbell, T. N., Pierce, P. R., Watkins, J. D., Huse, W. D., Bodkin, D., & Cheresh, D. A. (2000) · PubMed · Cited by 369 · see citing works

Distinct Antitumor Properties of a Type IV Collagen Domain Derived from Basement Membrane

Maeshima, Y., Colorado, P. C., de la Torre, A., Holthaus, K. A., Grunkemeyer, J. A., Ericksen, M. B., Hopfer, H., Xiao, Y., Stillman, I. E., & Kalluri, R. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m001956200 · Cited by 358 · see citing works

New Functions for Non-collagenous Domains of Human Collagen Type IV

Petitclerc, É., Boutaud, A., Prestayko, A. W., Xu, J., Sado, Y., Ninomiya, Y., Sarras, M. P., Hudson, B. G., & Brooks, P. C. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.275.11.8051 · Cited by 316 · see citing works

Signaling networks linking integrins and Rho family GTPases

Schwartz, M. A., & Shattil, S. J. (2000) · Trends in Biochemical Sciences · doi:10.1016/s0968-0004(00)01605-4 · Cited by 313 · see citing works

Monoclonal antibodies directed to different regions of vascular endothelial cadherin extracellular domain affect adhesion and clustering of the protein and modulate endothelial permeability

Corada, M. (2001) · Blood · doi:10.1182/blood.v97.6.1679 · Cited by 308 · see citing works

Platelet-derived Growth Factor Receptor β and Vascular Endothelial Growth Factor Receptor 2 Bind to the β3Integrin through Its Extracellular Domain

Borges, E., Jan, Y., & Ruoslahti, E. I. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m007040200 · Cited by 293 · see citing works

Matrix Attachment Regulates FAS-Induced Apoptosis in Endothelial Cells

Aoudjit, F., & Vuori, K. (2001) · The Journal of Cell Biology · doi:10.1083/jcb.152.3.633 · Cited by 290 · see citing works

Roles of two VEGF receptors, Flt-1 and KDR, in the signal transduction of VEGF effects in human vascular endothelial cells

Kanno, S., Oda, N., Abé, M., Terai, Y., Ito, M., Shitara, K., Tabayashi, K., Shibuya, M., & Sato, Y. (2000) · Oncogene · doi:10.1038/sj.onc.1203533 · Cited by 285 · see citing works

Endostatin-induced tyrosine kinase signaling through the Shb adaptor protein regulates endothelial cell apoptosis

Dixelius, J., Larsson, H. E., Sasaki, T., Holmqvist, K., Lu, L., Engström, Å., Timpl, R., Welsh, M., & Claesson, L. (2000) · Blood · doi:10.1182/blood.v95.11.3403 · Cited by 270 · see citing works

Molecular Basis of Angiogenesis: Role of VEGF and VE‐Cadherin

Carmeliet, P., & Collen, D. (2000) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2000.tb06320.x · Cited by 264 · see citing works

Disruption of matrix metalloproteinase 2 binding to integrin alpha vbeta 3 by an organic molecule inhibits angiogenesis and tumor growth in vivo

Silletti, S. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.011343298 · Cited by 262 · see citing works

Integrin alpha v beta 3 differentially regulates adhesive and phagocytic functions of the fibronectin receptor alpha 5 beta 1.

Blystone, S. D., Graham, I. L., Lindberg, F. P., & Brown, E. J. (1994) · The Journal of Cell Biology · doi:10.1083/jcb.127.4.1129 · Cited by 254 · see citing works

Interactions between mitogenic stimuli, or, a thousand and one connections

Schwartz, M. A., & Baron, V. T. (1999) · Current Opinion in Cell Biology · doi:10.1016/s0955-0674(99)80026-x · Cited by 245 · see citing works

Preferential Susceptibility of Brain Tumors to the Antiangiogenic Effects of an αv Integrin Antagonist

MacDonald, T. J., Taga, T., Shimada, H., Tabrizi, P., Zloković, B. V., Cheresh, D. A., & Laug, W. E. (2001) · Neurosurgery · doi:10.1097/00006123-200101000-00026 · Cited by 240 · see citing works

Vascular Endothelial (VE)-Cadherin: Only an Intercellular Glue?

Dejana, E., Bazzoni, G., & Lampugnani, M. G. (1999) · Experimental Cell Research · doi:10.1006/excr.1999.4601 · Cited by 239 · see citing works

Receptor Chimeras Indicate That the Vascular Endothelial Growth Factor Receptor-1 (VEGFR-1) Modulates Mitogenic Activity of VEGFR-2 in Endothelial Cells

Rahimi, N., Dayanir, V., & Lashkari, K. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m000528200 · Cited by 238 · see citing works

Identification of the Anti-angiogenic Site within Vascular Basement Membrane-derived Tumstatin

Maeshima, Y., Manfredi, M. G., Reimer, C., Holthaus, K. A., Hopfer, H., Chandamuri, B. R., Kharbanda, S. M., & Kalluri, R. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m007764200 · Cited by 229 · see citing works

Normal Development, Wound Healing, and Adenovirus Susceptibility in β5-Deficient Mice

Huang, X., Griffiths, M., Wu, J., Farese, R. V., & Sheppard, D. (2000) · Molecular and Cellular Biology · doi:10.1128/mcb.20.3.755-759.2000 · Cited by 215 · see citing works

Regulation of Integrin αvβ3-mediated Endothelial Cell Migration and Angiogenesis by Integrin α5β1 and Protein Kinase A

Kim, S., Harris, M., & Varner, J. A. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m003668200 · Cited by 213 · see citing works

Structural basis and potential role of heparin/heparan sulfate binding to the angiogenesis inhibitor endostatin

Sasaki, T., Larsson, H. E., Kreuger, J., Salmivirta, M., Claesson, L., Lindahl, U., Hohenester, E., & Timpl, R. (1999) · The EMBO Journal · doi:10.1093/emboj/18.22.6240 · Cited by 211 · see citing works

α6β4 and α6β1 Integrins Associate with ErbB-2 in Human Carcinoma Cell Lines

Falcioni, R., Antonini, A., Nisticò, P., Stefano, S. D., Crescenzi, M., Natali, P. G., & Sacchi, A. (1997) · Experimental Cell Research · doi:10.1006/excr.1997.3695 · Cited by 202 · see citing works

Mesodermal defects and cranial neural crest apoptosis in α5 integrin-null embryos

Goh, K. L., Yang, J. T., & Hynes, R. O. (1997) · Development · doi:10.1242/dev.124.21.4309 · Cited by 194 · see citing works

A repressor sequence in the juxtamembrane domain of Flt‐1 (VEGFR‐1) constitutively inhibits vascular endothelial growth factor‐dependent phosphatidylinositol 3′‐kinase activation and endothelial cell migration

Gille, H., Kowalski, J., Yu, L., Chen, H., Pisabarro, M. T., Davis-Smyth, T., & Ferrara, N. (2000) · The EMBO Journal · doi:10.1093/emboj/19.15.4064 · Cited by 180 · see citing works

Inhibition of angiogenesis and tumor growth by SCH221153, a dual alpha(v)beta3 and alpha(v)beta5 integrin receptor antagonist.

Kumar, C. C., Malkowski, M., Yin, Z., Tanghetti, E., Yaremko, B., Nechuta, T. L., Varner, J. A., Liu, M., Smith, E. M., Neustadt, B. R., et al. (2001) · PubMed · Cited by 172 · see citing works

The synergistic activity of αvβ3 integrin and pdgf receptor increases cell migration

Woodard, A. S., García‐Cardeña, G., Leong, M., Madri, J. A., Sessa, W. C., & Languino, L. R. (1998) · Journal of Cell Science · doi:10.1242/jcs.111.4.469 · Cited by 165 · see citing works

Cell Contact–dependent Activation of α3β1 Integrin Modulates Endothelial Cell Responses to Thrombospondin-1

Chandrasekaran, L. K., He, C.-Z., Al-Barazi, H., Krutzsch, H. C., Iruela‐Arispe, M. L., & Roberts, D. D. (2000) · Molecular Biology of the Cell · doi:10.1091/mbc.11.9.2885 · Cited by 156 · see citing works

Signaling properties of VEGF receptor-1 and -2 homo- and heterodimers

Huang, K., Andersson, C., Roomans, G. M., Ito, N., & Claesson, L. (2001) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/s1357-2725(01)00019-x · Cited by 141 · see citing works

Suppression of angiogenesis by lentiviral delivery of PEX, a noncatalytic fragment of matrix metalloproteinase 2

Pfeifer, A., Keßler, T., Silletti, S., Cheresh, D. A., & Verma, I. M. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.220399597 · Cited by 137 · see citing works

Integrin-associated protein immunoglobulin domain is necessary for efficient vitronectin bead binding.

Lindberg, F. P., Gresham, H. D., Reinhold, M. I., & Brown, E. J. (1996) · The Journal of Cell Biology · doi:10.1083/jcb.134.5.1313 · Cited by 136 · see citing works

Monoclonal antibody to vascular endothelial-cadherin is a potent inhibitor of angiogenesis, tumor growth, and metastasis.

Liao, F., Li, Y., O'Connor, W., Zanetta, L., Bassi, R., Santiago, A., Overholser, J. C., Hooper, A. T., Mignatti, P., Dejana, E., et al. (2000) · PubMed · Cited by 125 · see citing works

A Molecular Mechanism of Integrin Crosstalk: αvβ3 Suppression of Calcium/Calmodulin-dependent Protein Kinase II Regulates α5β1 Function

Blystone, S. D., Slater, S. E., Williams, M. P., Crow, M. T., & Brown, E. J. (1999) · The Journal of Cell Biology · doi:10.1083/jcb.145.4.889 · Cited by 118 · see citing works

Angiostatin inhibits endothelial and melanoma cellular invasion by blocking matrix-enhanced plasminogen activation

Stack, M. S., Gately, S. T., Bafetti, L. M., Enghild, J. J., & Soff, G. A. (1999) · Biochemical Journal · doi:10.1042/bj3400077 · Cited by 116 · see citing works

A peptidomimetic antagonist of the integrin alpha(v)beta3 inhibits Leydig cell tumor growth and the development of hypercalcemia of malignancy.

Carron, C., Meyer, D. M., Pegg, J. A., Engleman, V. W., Nickols, M. A., Settle, S. L., Westlin, W., Ruminski, P. G., & Nickols, G. A. (1998) · PubMed · Cited by 108 · see citing works

Rho Gtpases

Ridley, A. J. (2000) · The Journal of Cell Biology · doi:10.1083/jcb.150.4.f107 · Cited by 102 · see citing works

The αvβ3 Integrin Regulates α5β1-mediated Cell Migration toward Fibronectin

Simon, K. O., Nutt, E. M., Abraham, D. G., Rodan, G. A., & Duong, L. T. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.46.29380 · Cited by 91 · see citing works

Ligand binding to monocyte alpha 5 beta 1 integrin activates the alpha 2 beta 1 receptor via the alpha 5 subunit cytoplasmic domain and protein kinase C.

Pacifici, R., Roman, J., Kimble, R. B., Civitelli, R., Brownfield, C. M., & Bizzarri, C. (1994) · The Journal of Immunology · doi:10.4049/jimmunol.153.5.2222 · Cited by 79 · see citing works

Monoclonal antibody strategies to block angiogenesis

Hicklin, D. J., Witte, L., Zhu, Z., Liao, F., Wu, Y. L., Li, Y., & Böhlen, P. (2001) · Drug Discovery Today · doi:10.1016/s1359-6446(01)01759-7 · Cited by 70 · see citing works

Antiangiogenic agents

Klohs, W. D., & Hamby, J. M. (1999) · Current Opinion in Biotechnology · doi:10.1016/s0958-1669(99)00033-6 · Cited by 51 · see citing works

Small molecule αv integrin antagonists: novel anticancer agents

Kerr, J. S., Slee, A., & Mousa, S. A. (2000) · Expert Opinion on Investigational Drugs · doi:10.1517/13543784.9.6.1271 · Cited by 45 · see citing works

Endogenous Regulators of Angiogenesis – Emphasis on Proteins with Thrombospondin – Type I Motifs

Carpizo, D. R., & Iruela-Arispe, M. L. (2000) · Cancer and Metastasis Reviews · doi:10.1023/a:1026570331022 · Cited by 44 · see citing works

Role of the Vascular Endothelial Growth Factor Pathway in Tumor Growth and Angiogenesis

Hicklin, D. J., & Ellis, L. M. (2004) · Journal of Clinical Oncology · doi:10.1200/jco.2005.06.081 · Cited by 3,010 · see citing works

Basement membranes: structure, assembly and role in tumour angiogenesis

Kalluri, R. (2003) · Nature reviews. Cancer · doi:10.1038/nrc1094 · Cited by 1,748 · see citing works

Endothelial Cell Migration During Angiogenesis

Lamalice, L., Bœuf, F. L., & Huot, J. (2007) · Circulation Research · doi:10.1161/01.res.0000259593.07661.1e · Cited by 1,486 · see citing works

Integrin signalling during tumour progression

Guo, W., & Giancotti, F. G. (2004) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm1490 · Cited by 1,473 · see citing works

Tissue-Penetrating Delivery of Compounds and Nanoparticles into Tumors

Sugahara, K. N., Teesalu, T., Karmali, P. P., Kotamraju, V. R., Agemy, L., Girard, O. M., Hanahan, D., Mattrey, R. F., & Ruoslahti, E. I. (2009) · Cancer Cell · doi:10.1016/j.ccr.2009.10.013 · Cited by 1,140 · see citing works

Therapeutic strategies for rheumatoid arthritis

Smolen, J. S., & Steiner, G. E. (2003) · Nature Reviews Drug Discovery · doi:10.1038/nrd1109 · Cited by 915 · see citing works

Tumor Regression by Targeted Gene Delivery to the Neovasculature

Hood, J. D., Bednarski, M. D., Frausto, R. F., Guccione, S., Reisfeld, R. A., Xiang, R., & Cheresh, D. A. (2002) · Science · doi:10.1126/science.1070200 · Cited by 858 · see citing works

Networks and crosstalk: integrin signalling spreads

Schwartz, M. A., & Ginsberg, M. H. (2002) · Nature Cell Biology · doi:10.1038/ncb0402-e65 · Cited by 797 · see citing works

Derailed endocytosis: an emerging feature of cancer

Mosesson, Y., Mills, G. B., & Yarden, Y. (2008) · Nature reviews. Cancer · doi:10.1038/nrc2521 · Cited by 719 · see citing works

Nanomedicine for drug delivery and imaging: A promising avenue for cancer therapy and diagnosis using targeted functional nanoparticles

Liu, Y., Miyoshi, H., & Nakamura, M. (2007) · International Journal of Cancer · doi:10.1002/ijc.22709 · Cited by 620 · see citing works

Reversal of obesity by targeted ablation of adipose tissue

Kolonin, M. G., Saha, P., Chan, L., Pasqualini, R., & Arap, W. (2004) · Nature Medicine · doi:10.1038/nm1048 · Cited by 596 · see citing works

A reevaluation of integrins as regulators of angiogenesis

Hynes, R. O. (2002) · Nature Medicine · doi:10.1038/nm0902-918 · Cited by 546 · see citing works

cRGD‐Functionalized Polymer Micelles for Targeted Doxorubicin Delivery

Nasongkla, N., Shuai, X., Ai, H., Weinberg, B. D., Pink, J. J., Boothman, D. A., & Gao, J. (2004) · Angewandte Chemie International Edition · doi:10.1002/anie.200460800 · Cited by 434 · see citing works

The role of VEGF receptors in angiogenesis; complex partnerships

Suarez, S., Zehnder-Fjällman, A. H. M., & Ballmer‐Hofer, K. (2006) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-005-5426-3 · Cited by 406 · see citing works

Matrix metalloproteinases in tumor–host cell communication

Lynch, C. C., & Matrisian, L. M. (2002) · Differentiation · doi:10.1046/j.1432-0436.2002.700909.x · Cited by 384 · see citing works

Arterial Wall Shear Stress: Observations from the Bench to the Bedside

Paszkowiak, J. J., & Dardik, A. (2003) · Vascular and Endovascular Surgery · doi:10.1177/153857440303700107 · Cited by 344 · see citing works

Galectin-3 is an important mediator of VEGF- and bFGF-mediated angiogenic response

Markowska, A. I., Liu, F., & Panjwani, N. (2010) · The Journal of Experimental Medicine · doi:10.1084/jem.20090121 · Cited by 330 · see citing works

αVβ3 Integrin-Targeted PLGA-PEG Nanoparticles for Enhanced Anti-tumor Efficacy of a Pt(IV) Prodrug

Graf, N., Bielenberg, D. R., Kolishetti, N., Muus, C., Banyard, J., Farokhzad, O. C., & Lippard, S. J. (2012) · ACS Nano · doi:10.1021/nn301148e · Cited by 327 · see citing works

Conditional knockout of focal adhesion kinase in endothelial cells reveals its role in angiogenesis and vascular development in late embryogenesis

Shen, T., Park, A. Y. J., Alcaraz, A., Peng, X., Jang, I. K., Koni, P. A., Flavell, R. A., Gu, H., & Guan, J. (2005) · The Journal of Cell Biology · doi:10.1083/jcb.200411155 · Cited by 305 · see citing works

Tumor-specific expression of αvβ3 integrin promotes spontaneous metastasis of breast cancer to bone

Sloan, E. K., Pouliot, N., Stanley, K. L., Chia, J., Moseley, J. M., Hards, D. K., & Anderson, R. L. (2006) · Breast Cancer Research · doi:10.1186/bcr1398 · Cited by 276 · see citing works

Cell‐cell signaling by direct contact increases cell proliferation via a PI3K‐dependent signal

Nelson, C. M., & Chen, C. S. (2002) · FEBS Letters · doi:10.1016/s0014-5793(02)02370-0 · Cited by 264 · see citing works

Stromal cells promote angiogenesis and growth of human prostate tumors in a differential reactive stroma (DRS) xenograft model.

Tuxhorn, J. A., McAlhany, S. J., Dang, T. D., Ayala, G. E., & Rowley, D. R. (2002) · PubMed · Cited by 261 · see citing works

Regulation of tumor angiogenesis by integrin-linked kinase (ILK)

Tan, C., Cruet-Hennequart, S., Troussard, A. A., Fazli, L., Costello, P., Sutton, K., Wheeler, J., Gleave, M. E., Sanghera, J. S., & Dedhar, S. (2004) · Cancer Cell · doi:10.1016/s1535-6108(03)00281-2 · Cited by 260 · see citing works

Pro-angiogenic Activities of CYR61 (CCN1) Mediated through Integrins αvβ3 and α6β1 in Human Umbilical Vein Endothelial Cells

Leu, S.-J., Lam, S. C.-T., & Lau, L. F. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m209288200 · Cited by 247 · see citing works

Phage Nanofibers Induce Vascularized Osteogenesis in 3D Printed Bone Scaffolds

Wang, J., Yang, M., Zhu, Y., Wang, L., Tomsia, A. P., & Mao, C. (2014) · Advanced Materials · doi:10.1002/adma.201400154 · Cited by 239 · see citing works

CCN3 (NOV) Is a Novel Angiogenic Regulator of the CCN Protein Family

Lin, C. G., Leu, S.-J. J., Chen, N., Tebeau, C. M., Lin, S.-X., Yeung, C. Y., & Lau, L. F. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m302028200 · Cited by 211 · see citing works

Tumor αvβ3 Integrin Is a Therapeutic Target for Breast Cancer Bone Metastases

Zhao, Y., Bachelier, R., Treilleux, I., Pujuguet, P., Peyruchaud, O., Baron, R., Clément-Lacroix, P., & Clézardin, P. (2007) · Cancer Research · doi:10.1158/0008-5472.can-06-4499 · Cited by 210 · see citing works

The emergence of integrins: a personal and historical perspective

Hynes, R. O. (2004) · Matrix Biology · doi:10.1016/j.matbio.2004.08.001 · Cited by 209 · see citing works

Matrix metalloproteinases, angiogenesis, and cancer: commentary re: A. C. Lockhart et al., Reduction of wound angiogenesis in patients treated with BMS-275291, a broad spectrum matrix metalloproteinase inhibitor. Clin. Cancer Res., 9: 00-00, 2003.

Rundhaug, J. E. (2003) · PubMed · Cited by 187 · see citing works

Differential Interactions of FGFs with Heparan Sulfate Control Gradient Formation and Branching Morphogenesis

Makarenkova, H., Hoffman, M., Beenken, A., Eliseenkova, A. V., Meech, R., Tsau, C., Patel, V., Lang, R., & Mohammadi, M. (2009) · Science Signaling · doi:10.1126/scisignal.2000304 · Cited by 194 · see citing works

Self-assembling short oligopeptides and the promotion of angiogenesis

Narmoneva, D. A., Oni, O., Sieminski, A. L., Zhang, S., Gertler, J. P., Kamm, R. D., & Lee, R. T. (2005) · Biomaterials · doi:10.1016/j.biomaterials.2005.01.005 · Cited by 183 · see citing works

Vascular integrins: pleiotropic adhesion and signaling molecules in vascular homeostasis and angiogenesis

Rüegg, C., & Mariotti, A. (2003) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-003-2297-3 · Cited by 178 · see citing works

Heparanase mediates cell adhesion independent of its enzymatic activity

Goldshmidt, O., Zcharia, E., Cohen, M., Aingorn, H., Cohen, I., Nadav, L., Katz, B., Geiger, B., & Vlodavsky, I. (2003) · The FASEB Journal · doi:10.1096/fj.02-0773com · Cited by 176 · see citing works

Integrins as Unique Receptors for Vascular Control

Martinez‐Lemus, L. A., Wu, X. Y., Wilson, E., Hill, M. A., Davis, G. E., Davis, M. J., & Meininger, G. A. (2003) · Journal of Vascular Research · doi:10.1159/000071886 · Cited by 175 · see citing works

Integrin signaling: it's where the action is

Damsky, C. H., & Ilić, D. (2002) · Current Opinion in Cell Biology · doi:10.1016/s0955-0674(02)00368-x · Cited by 171 · see citing works

Integrins and bone metastasis: Integrating tumor cell and stromal cell interactions

Schneider, J. G., Amend, S. R., & Weilbaecher, K. N. (2010) · Bone · doi:10.1016/j.bone.2010.09.016 · Cited by 170 · see citing works

Breast cancer-induced angiogenesis: multiple mechanisms and the role of the microenvironment

Boudreau, N. J., & Myers, C. A. (2003) · Breast Cancer Research · doi:10.1186/bcr589 · Cited by 164 · see citing works

Polymeric prodrugs

Hoste, K., Winne, K. D., & Schacht, E. H. (2004) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2003.07.016 · Cited by 166 · see citing works

Cell-autonomous requirement for β1 integrin in endothelial cell adhesion, migration and survival during angiogenesis in mice

Carlson, T. R., Hu, H., Braren, R., Kim, Y. H., & Wang, R. A. (2008) · Development · doi:10.1242/dev.016378 · Cited by 157 · see citing works

Vascular Integrins in Tumor Angiogenesis: Mediators and Therapeutic Targets

Alghisi, G. C., & Rüegg, C. (2006) · Endothelium · doi:10.1080/10623320600698037 · Cited by 159 · see citing works

Cellular and Gene Expression Responses Involved in the Rapid Growth Inhibition of Human Cancer Cells by RNA Interference-mediated Depletion of Telomerase RNA

Li, S., Crothers, J., Haqq, C. M., & Blackburn, E. H. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m502782200 · Cited by 158 · see citing works

Direct Binding of Integrin αvβ3 to FGF1 Plays a Role in FGF1 Signaling

Mori, S., Wu, C., Yamaji, S., Saegusa, J., Shi, B., Ma, Z., Kuwabara, Y., Lam, K. S., Isseroff, R. R., Takada, Y. K., et al. (2008) · Journal of Biological Chemistry · doi:10.1074/jbc.m801213200 · Cited by 154 · see citing works

Canstatin Acts on Endothelial and Tumor Cells via Mitochondrial Damage Initiated through Interaction with αvβ3 and αvβ5 Integrins

Magnon, C., Galaup, A., Mullan, B., Rouffiac, V., Bidart, J., Griscelli, F., Opolon, P., & Perricaudet, M. (2005) · Cancer Research · doi:10.1158/0008-5472.can-04-3536 · Cited by 152 · see citing works

Applications of Nanoparticles for MRI Cancer Diagnosis and Therapy

Błasiak, B., van Veggel, F. C. J. M., & Tomanek, B. (2013) · Journal of Nanomaterials · doi:10.1155/2013/148578 · Cited by 138 · see citing works

The Diverse Roles of Integrins and Their Ligands in AngiogenesisPreprint

Hynes, R. O., Lively, J. C., McCarty, J. H., Taverna, D., Francis, S., Hodivala‐Dilke, K., & XIAO, Q. (2002) · Cold Spring Harbor Symposia on Quantitative Biology · doi:10.1101/sqb.2002.67.143 · Cited by 138 · see citing works

αv integrins regulate cell proliferation through integrin-linked kinase (ILK) in ovarian cancer cells

Cruet-Hennequart, S., Maubant, S., Luis, J., Gauduchon, P., Staedel, C., & Dedhar, S. (2003) · Oncogene · doi:10.1038/sj.onc.1206347 · Cited by 137 · see citing works

Perlecan and Tumor Angiogenesis

Jiang, X., & Couchman, J. (2003) · Journal of Histochemistry & Cytochemistry · doi:10.1177/002215540305101101 · Cited by 134 · see citing works

The role of β3-integrins in tumor angiogenesis: context is everything

Robinson, S. D., & Hodivala‐Dilke, K. (2011) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2011.03.014 · Cited by 132 · see citing works

Molecular imaging of gene expression and protein function in vivo with PET and SPECT

Sharma, V., Luker, G. D., & Piwnica-Worms, D. R. (2002) · Journal of Magnetic Resonance Imaging · doi:10.1002/jmri.10182 · Cited by 132 · see citing works

Low Molecular Weight Fucoidan Increases VEGF165-induced Endothelial Cell Migration by Enhancing VEGF165 Binding to VEGFR-2 and NRP1

Lake, A. C., Vassy, R., Benedetto, M. D., Lavigne, D., Visage, C. L., Perret, G. Y., & Letourneur, D. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m600686200 · Cited by 129 · see citing works

Plasmin-induced Migration of Endothelial Cells

Tarui, T., Majumdar, M., Miles, L. A., Ruf, W., & Takada, Y. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m205514200 · Cited by 127 · see citing works

Extracellular matrix regulates endothelial functions through interaction of VEGFR‐3 and integrin α5β1

Zhang, X., Groopman, J. E., & Wang, J. F. (2004) · Journal of Cellular Physiology · doi:10.1002/jcp.20106 · Cited by 126 · see citing works

Therapeutic Effect of Human Umbilical Cord Multipotent Mesenchymal Stromal Cells in a Rat Model of Stroke

Liao, W., Xie, J., Zhong, J., Liu, Y.-J., Du, L., Zhou, B., Xu, J., Liu, P., Yang, S., Wang, J., et al. (2009) · Transplantation · doi:10.1097/tp.0b013e318195742e · Cited by 125 · see citing works

VEGF-initiated angiogenesis and the uPA/uPAR system

Breuss, J. M., & Uhrín, P. (2012) · Cell Adhesion & Migration · doi:10.4161/cam.22243 · Cited by 123 · see citing works

α5β1 Integrin Activates an NF-κB-Dependent Program of Gene Expression Important for Angiogenesis and Inflammation

Klein, S., de Fougerolles, A. R., Blaikie, P., Khan, L., Pepe, A., Green, C. D., Koteliansky, V., & Giancotti, F. G. (2002) · Molecular and Cellular Biology · doi:10.1128/mcb.22.16.5912-5922.2002 · Cited by 121 · see citing works

Placental Extracellular Matrix: Gene Expression, Deposition by Placental Fibroblasts and the Effect of Oxygen

Chen, C. P., & Aplin, J. D. (2003) · Placenta · doi:10.1053/plac.2002.0904 · Cited by 119 · see citing works

Aberrant vascular architecture in tumors and its importance in drug-based therapies

Munn, L. L. (2003) · Drug Discovery Today · doi:10.1016/s1359-6446(03)02686-2 · Cited by 119 · see citing works

Integrins in the development function and dysfunction of the nervous system

Clegg, D. (2003) · Frontiers in bioscience · doi:10.2741/1020 · Cited by 119 · see citing works

A mathematical model of the contribution of endothelial progenitor cells to angiogenesis in tumors: implications for antiangiogenic therapy

Stoll, B. R., Migliorini, C., Kadambi, A., Munn, L. L., & Jain, R. K. (2003) · Blood · doi:10.1182/blood-2003-02-0365 · Cited by 117 · see citing works

Detection of Injury-Induced Vascular Remodeling by Targeting Activated α v β 3 Integrin In Vivo

Sadeghi, M. M., Krassilnikova, S., Zhang, J., Gharaei, A. A., Fassaei, H. R., Esmailzadeh, L., Kooshkabadi, A., Edwards, S., Yalamanchili, P., Harris, T. D., et al. (2004) · Circulation · doi:10.1161/01.cir.0000133319.84326.70 · Cited by 117 · see citing works

Endothelial cell integrins and COX-2: mediators and therapeutic targets of tumor angiogenesis

Rüegg, C., Dormond, O., & Mariotti, A. (2003) · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer · doi:10.1016/j.bbcan.2003.09.003 · Cited by 114 · see citing works

The role of CD44 in pathological angiogenesis

Chen, L., Fu, C., Zhang, Q., He, C., Zhang, F., & Wei, Q. (2020) · The FASEB Journal · doi:10.1096/fj.202000380rr · Cited by 110 · see citing works

Overexpression of focal adhesion kinase in vascular endothelial cells promotes angiogenesis in transgenic mice

Peng, X., Ueda, H., Zhou, H., Stokol, T., Shen, T., ALCARAZ, A., Nagy, T., Vassalli, J. D., & Guan, J. (2004) · Cardiovascular Research · doi:10.1016/j.cardiores.2004.07.012 · Cited by 110 · see citing works

The extracellular adherence protein (Eap) of Staphylococcus aureus inhibits wound healing by interfering with host defense and repair mechanisms

Athanasopoulos, A. N. (2006) · Blood · doi:10.1182/blood-2005-08-3140 · Cited by 109 · see citing works

Functional disruption of α4 integrin mobilizes bone marrow–derived endothelial progenitors and augments ischemic neovascularization

Qin, G., Ii, M., Silver, M., Wecker, A., Bord, E., Ma, H., Gavin, M., Goukassian, D. A., Yoon, Y., Papayannopoulou, T., et al. (2006) · The Journal of Experimental Medicine · doi:10.1084/jem.20050459 · Cited by 109 · see citing works

Antibody against Junctional Adhesion Molecule-C Inhibits Angiogenesis and Tumor Growth

Lamagna, C., Hodivala‐Dilke, K., Imhof, B. A., & Aurrand‐Lions, M. (2005) · Cancer Research · doi:10.1158/0008-5472.can-04-4012 · Cited by 107 · see citing works

Peptides as drug delivery vehicles across biological barriers

Ghosh, D., Peng, X., Leal, J., & Mohanty, R. P. (2017) · Journal of Pharmaceutical Investigation · doi:10.1007/s40005-017-0374-0 · Cited by 106 · see citing works

In Vivo Targeting of Tumor Endothelial Cells by Systemic Delivery of Lentiviral Vectors

Palma, M. D., Venneri, M. A., & Naldini, L. (2003) · Human Gene Therapy · doi:10.1089/104303403322168028 · Cited by 105 · see citing works

cRGD‐Functionalized Polymer Micelles for Targeted Doxorubicin Delivery

Nasongkla, N., Shuai, X., Ai, H., Weinberg, B. D., Pink, J. J., Boothman, D. A., & Gao, J. (2004) · Angewandte Chemie · doi:10.1002/ange.200460800 · Cited by 105 · see citing works

The angiogenic regulator CD13/APN is a transcriptional target of Ras signaling pathways in endothelial morphogenesis

Bhagwat, S. V., Petrovic, N., Okamoto, Y., & Shapiro, L. H. (2003) · Blood · doi:10.1182/blood-2002-05-1422 · Cited by 104 · see citing works

Increased expression of fibronectin and the α5β1 integrin in angiogenic cerebral blood vessels of mice subject to hypobaric hypoxia

Milner, R., Hung, S. Y., Erokwu, B. O., Dore‐Duffy, P., LaManna, J. C., & del Zoppo, G. J. (2008) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2008.01.013 · Cited by 103 · see citing works

Kininogens: More than cysteine protease inhibitors and kinin precursors

Lalmanach, G., Naudin, C., Lecaille, F., & Fritz, H. (2010) · Biochimie · doi:10.1016/j.biochi.2010.03.011 · Cited by 102 · see citing works

Sulfonamide derivative, E7820, is a unique angiogenesis inhibitor suppressing an expression of integrin alpha2 subunit on endothelium.

Funahashi, Y., Sugi, N. H., Semba, T., Yamamoto, Y., Hamaoka, S., Tsukahara-Tamai, N., Ozawa, Y., Tsuruoka, A., Nara, K., Takahashi, K., et al. (2002) · PubMed · Cited by 102 · see citing works

α 4 β 1 Integrin Mediates Selective Endothelial Cell Responses to Thrombospondins 1 and 2 In Vitro and Modulates Angiogenesis In Vivo

Calzada, M. J., Zhou, L., Sipes, J. M., Zhang, J., Krutzsch, H. C., Iruela‐Arispe, M. L., Annis, D. S., Mosher, D. F., & Roberts, D. D. (2003) · Circulation Research · doi:10.1161/01.res.0000115555.05668.93 · Cited by 101 · see citing works

The role of integrins in tumor angiogenesis

Hwang, R. F., & Varner, J. A. (2004) · Hematology/Oncology Clinics of North America · doi:10.1016/j.hoc.2004.09.010 · Cited by 101 · see citing works

Evidence of Antiangiogenic and Antimetastatic Activities of the Recombinant Disintegrin Domain of Metargidin

Trochon-Joseph, V., Martel-Renoir, D., Mir, L. M., Thomaïdis, A., Opolon, P., Connault, E., Li, H., Grenet, C., Fauvel-Lafève, F., Soria, J., et al. (2004) · Cancer Research · doi:10.1158/0008-5472.can-03-3272 · Cited by 99 · see citing works

Integrins regulate VE-cadherin and catenins: Dependence of this regulation on Src, but not on Ras

Wang, Y., Jin, G., Miao, H., Li, J. Y.-S., Usami, S., & Chien, S. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0510774103 · Cited by 97 · see citing works

Bimolecular Interaction of Insulin-Like Growth Factor (IGF) Binding Protein-2 with αvβ3 Negatively Modulates IGF-I-Mediated Migration and Tumor Growth

Pereira, J. J., Meyer, T., Docherty, S. E., Reid, H. H., Marshall, J. F., Thompson, E. W., Rossjohn, J., & Price, J. T. (2004) · Cancer Research · doi:10.1158/0008-5472.can-03-3056 · Cited by 96 · see citing works

Roles of blood-brain barrier integrins and extracellular matrix in stroke

Edwards, D. N., & Bix, G. J. (2018) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00151.2018 · Cited by 90 · see citing works

Combination of Integrin-Binding Peptide and Growth Factor Promotes Cell Adhesion on Electron-Beam-Fabricated Patterns

Kolodziej, C. M., Kim, S. H., Broyer, R. M., Saxer, S., Decker, C. G., & Maynard, H. D. (2011) · Journal of the American Chemical Society · doi:10.1021/ja205524x · Cited by 87 · see citing works

Radiolabelled RGD peptides and peptidomimetics for tumour targeting

Haubner, R. (2009) · Frontiers in bioscience · doi:10.2741/3283 · Cited by 86 · see citing works

VEGF profiling and angiogenesis in human microtissues

Kelm, J. M., Sánchez-Bustamante, C. D., Ehler, E., Hoerstrup, S. P., Djonov, V., Ittner, L. M., & Fussenegger, M. (2005) · Journal of Biotechnology · doi:10.1016/j.jbiotec.2005.03.016 · Cited by 86 · see citing works

Rac regulates integrin-mediated endothelial cell adhesion and migration on laminin-8

Fujiwara, H., Gu, J., & Sekiguchi, K. (2003) · Experimental Cell Research · doi:10.1016/j.yexcr.2003.08.010 · Cited by 84 · see citing works

Thymidine Phosphorylase and 2-Deoxyribose Stimulate Human Endothelial Cell Migration by Specific Activation of the Integrins α5β1 and αVβ3

Hotchkiss, K. A., Ashton, A. W., & Schwartz, E. L. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m212670200 · Cited by 83 · see citing works

Targeting ECM–Integrin Interaction with Liposome-Encapsulated Small Interfering RNAs Inhibits the Growth of Human Prostate Cancer in a Bone Xenograft Imaging Model

Bisanz, K. M., Yu, J., Edlund, M., Spohn, B., Hung, M., Chung, L. W. K., & Hsieh, C. (2005) · Molecular Therapy · doi:10.1016/j.ymthe.2005.05.012 · Cited by 83 · see citing works

Lunasin suppresses the migration and invasion of breast cancer cells by inhibiting matrix metalloproteinase-2/-9 via the FAK/Akt/ERK and NF-κB signaling pathways

Jiang, Q., Pan, Y., Cheng, Y., Li, H., Liu, D., & Li, H. (2016) · Oncology Reports · doi:10.3892/or.2016.4798 · Cited by 83 · see citing works

Non steroidal anti‐inflammatory drugs and COX‐2 inhibitors as anti‐cancer therapeutics: hypes, hopes and reality

Rüegg, C., Zarić, J., & Stupp, R. (2003) · Annals of Medicine · doi:10.1080/07853890310017053 · Cited by 77 · see citing works

Modulation of prostate cancer growth in bone microenvironments

Edlund, M., Sung, S., & Chung, L. W. K. (2003) · Journal of Cellular Biochemistry · doi:10.1002/jcb.10702 · Cited by 77 · see citing works

Biological and molecular properties of a new αvβ3/αvβ5 integrin antagonist

Belvisi, L., Riccioni, T., Marcellini, M., Vesci, L., Chiarucci, I., Efrati, D., Potenza, D., Scolastico, C., Manzoni, L., Lombardo, K., et al. (2005) · Molecular Cancer Therapeutics · doi:10.1158/1535-7163.mct-05-0120 · Cited by 76 · see citing works

Chapter 3 Endothelial Cell Adhesion and Migration

Reinhart‐King, C. A. (2008) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/s0076-6879(08)02003-x · Cited by 75 · see citing works

Role of Integrins in Regulating Proteases to Mediate Extracellular Matrix Remodeling

Jiao, Y., Zhang, K., & Chen, J. (2012) · Cancer Microenvironment · doi:10.1007/s12307-012-0101-3 · Cited by 75 · see citing works

Correlating Global Gene Regulation to Angiogenesis in the Developing Chick Extra-Embryonic Vascular System

Javerzat, S., Franco, M., Herbert, J. M. J., Platonova, N., Peille, A.-L., Pantesco, V., Vos, J. D., Assou, S., Bicknell, R., Bikfalvi, A., et al. (2009) · PLoS ONE · doi:10.1371/journal.pone.0007856 · Cited by 75 · see citing works

Integrin Regulation by Vascular Endothelial Growth Factor in Human Brain Microvascular Endothelial Cells

Lee, T.-H., Seng, S., Li, H., Kennel, S. J., Avraham, H. K., & Avraham, S. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m607525200 · Cited by 74 · see citing works

An Angiogenesis Inhibitor E7820 Shows Broad-Spectrum Tumor Growth Inhibition in a Xenograft Model

Semba, T., Funahashi, Y., Ono, N., Yamamoto, Y., Sugi, N. H., Asada, M., Yoshimatsu, K., & Wakabayashi, T. (2004) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-0109-03 · Cited by 74 · see citing works

Inhibitors of integrins

Tucker, G. (2002) · Current Opinion in Pharmacology · doi:10.1016/s1471-4892(02)00175-3 · Cited by 73 · see citing works

Odontoblasts induced from mesenchymal cells of murine dental papillae in three-dimensional cell culture

Kikuchi, H., Suzuki, K., Sakai, N., & Yamada, S. (2004) · Cell and Tissue Research · doi:10.1007/s00441-004-0882-x · Cited by 72 · see citing works

Effect of magnesium-degradation products and hypoxia on the angiogenesis of human umbilical vein endothelial cells

Xu, L., Willumeit‐Römer, R., & Luthringer-Feyerabend, B. (2019) · Acta Biomaterialia · doi:10.1016/j.actbio.2019.02.018 · Cited by 73 · see citing works

HIV-1 Tat Regulates Endothelial Cell Cycle Progression via Activation of the Ras/ERK MAPK Signaling Pathway

Toschi, E., Bacigalupo, I., Strippoli, R., Chiozzini, C., Cereseto, A., Falchi, M., Nappi, F., Sgadari, C., Barillari, G., Mainiero, F., et al. (2006) · Molecular Biology of the Cell · doi:10.1091/mbc.e05-08-0717 · Cited by 72 · see citing works

Regulation of angiogenesis by the aging suppressor gene klotho

Fukino, K., Suzuki, T., Saito, Y., Shindo, T., Amaki, T., Kurabayashi, M., & Nagai, R. (2002) · Biochemical and Biophysical Research Communications · doi:10.1016/s0006-291x(02)00216-4 · Cited by 70 · see citing works

Integrins in angiogenesis: multitalented molecules in a balancing act

Hodivala‐Dilke, K., Reynolds, A. R., & Reynolds, L. E. (2003) · Cell and Tissue Research · doi:10.1007/s00441-003-0774-5 · Cited by 156 · see citing works

Integrins and Angiogenesis

Stupack, D. G., & Cheresh, D. A. (2004) · Current topics in developmental biology/Current Topics in Developmental Biology · doi:10.1016/s0070-2153(04)64009-9 · Cited by 297 · see citing works

Vascular integrins: pleiotropic adhesion and signaling molecules in vascular homeostasis and angiogenesis

Rüegg, C., & Mariotti, A. (2003) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-003-2297-3 · Cited by 178 · see citing works

Role of Integrins in Angiogenesis

Tabatabai, G., & Weller, M. (2013) · Springer eBooks · doi:10.1007/978-1-4614-5857-9_5 · Cited by 1 · see citing works

Integrins

Silva, R., D’Amico, G., Hodivala‐Dilke, K., & Reynolds, L. E. (2008) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.108.172015 · Cited by 254 · see citing works