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Cited by 465

The DOI matches its Crossref record; 76 of the 76 references it cites were found in a registry or an index.

Integrin signaling: specificity and control of cell survival and cell cycle progression

Open access
Giancotti, Filippo G·1997·Current Opinion in Cell Biology

Abstract

Integrin-mediated adhesion to the extracellular matrix plays an important role in regulating cell survival and proliferation. There is now increasing evidence that integrins activate shared as well as subgroup-specific signaling pathways. The signals from these adhesion receptors are integrated with those originating from growth factor and cytokine receptors in order to organize the cytoskeleton, stimulate mitogen-activated protein kinase cascades, and regulate immediate early gene expression. The repertoire of integrins and composition of the extracellular matrix appear to dictate whether a cell will survive, proliferate or exit the cell cycle and differentiate in response to soluble factors.

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Integrity signals

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Metadata

Authors
Giancotti, F. G.
Venue
Current Opinion in Cell Biology
Publisher
Elsevier BV
Published
1997-10
Volume
9
Issue
5
Pages
691-700
ISSN
0955-0674 (ISSN-L)
OpenAlex
W2014662502
Cited by
465
References
76
FWCI
3.06
Type
journal article
Language
en
Open access
hybrid

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CoChat. (2026). Citation check: Integrin signaling: specificity and control of cell survival and cell cycle progression. https://app.cochat.ai/papers/10.1016/s0955-0674(97)80123-8
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Giancotti, F. G. (1997). Integrin signaling: specificity and control of cell survival and cell cycle progression. Current Opinion in Cell Biology. https://doi.org/10.1016/s0955-0674(97)80123-8

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.