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Rac is required for v-Abl tyrosine kinase to activate mitogenesis
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“Rac GTPases have been previously implicated in p210-BCR-ABL-mediated transformation (Sini et al., 2004;Renshaw et al., 1996;Skorski et al., 1998;Harnois et al., 2003;Burridge and Wennerberg, 2004;Schwartz, 2004)”
From Rac Guanosine Triphosphatases Represent Integrating Molecular Therapeutic Targets for BCR-ABL-Induced Myeloproliferative Disease (2007) · cites this paper as Renshaw et al., 1996
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Research works printed but not linked: 26
- Nobes, 1995, Rho, Rac and Cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia, Cell, 81, 53, 10.1016/0092-8674(95)90370-4 · DOI
- Nishiyama, 1994, Rac p21 is involved in insulin-induced membrane ruffling and rho p21 is involved in hepatocyte growth factor- and 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced membrane ruffling in KB cells, Mol Cell Biol, 14, 2447, 10.1128/MCB.14.4.2447 · DOI
- Ridley, 1992, The small GTP-binding protein rac regulates growth factor-induced membrane ruffling, Cell, 70, 401, 10.1016/0092-8674(92)90164-8 · DOI
- Bokoch, 1994, Regulation of the human neutrophil NADPH oxidase by the Rac GTP-binding proteins, Curr Opin Cell Biol, 6, 212, 10.1016/0955-0674(94)90138-4 · DOI
- Qui, 1995, An essential role for Rac in Ras transformation, Nature, 374, 457, 10.1038/374457a0 · DOI
- Khosravi-Far, 1995, Activation of rac1, rhoA, and mitogen activated protein kinases is required for ras transformation, Mol Cell Biol, 15, 6443, 10.1128/MCB.15.11.6443 · DOI · Paper page
- Hill, 1995, The Rho family GTPases RhoA, Rac1, and CDC42Hs regulate transcriptional activation by SRF, Cell, 81, 1159, 10.1016/S0092-8674(05)80020-0 · DOI
- Coso, 1995, The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway, Cell, 81, 1137, 10.1016/S0092-8674(05)80018-2 · DOI · Paper page
- Minden, 1995, Selective activation of the JNK signaling cascade and c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs, Cell, 81, 1147, 10.1016/S0092-8674(05)80019-4 · DOI
- Olson, 1995, An essential role for Rho, Rac, and Cdc42 GTPases in cell cycle progression through G1, Science, 269, 1270, 10.1126/science.7652575 · DOI
- Renshaw, 1992, Oncogenic v-abl tyrosine kinase can inhibit or stimulate growth, depending on the cell context, EMBO J, 11, 3941, 10.1002/j.1460-2075.1992.tb05488.x · DOI
- Huang, 1995, Biological response to phorbol ester determined by alternative G1 pathways, Proc Natl Acad Sci USA, 92, 4793, 10.1073/pnas.92.11.4793 · DOI
- Varticovski, 1991, Activation of phosphatidylinositol 3-kinase in cells expressing abl oncogene variants, Mol Cell Biol, 11, 1107, 10.1128/MCB.11.2.1107 · DOI
- Hawkins, 1995, PDGF stimulates an increase in GTP–Rac via activation of phosphoinositide 3-kinase, Curr Biol, 5, 393, 10.1016/S0960-9822(95)00080-7 · DOI
- Renshaw, 1995, The human leukemia oncogene bcr–abl abrogates the anchorage requirement but not the growth factor requirement for proliferation, Mol Cell Biol, 15, 1286, 10.1128/MCB.15.3.1286 · DOI
- McWhirter, 1991, Activation of tyrosine kinase and microfilament-binding functions of c-abl by bcr sequences in bcr/abl fusion proteins, Mol Cell Biol, 11, 1553, 10.1128/MCB.11.3.1553 · DOI
- McWhirter, 1993, An actin-binding function contributes to transformation by the Bcr–Abl oncoprotein of Philadelphia chromosome-positive human leukemias, EMBO J, 12, 1533, 10.1002/j.1460-2075.1993.tb05797.x · DOI
- Minden, 1994, Differential activation of ERK and JNK mitogen-activated protein kinases by Raf-1 and MEKK, Science, 266, 1719, 10.1126/science.7992057 · DOI
- Peppelenbosch, 1995, Rac mediates growth factor-induced arachidonic acid release, Cell, 81, 849, 10.1016/0092-8674(95)90005-5 · DOI
- Yu, 1990, Serum stimulation of NIH 3T3 cells induces the production of lipids able to inhibit GTPase-activating protein activity, Mol Cell Biol, 10, 6683, 10.1128/MCB.10.12.6683 · DOI
- Kipreos, 1987, Isolation of temperature-sensitive tyrosine kinase mutants of v-abl oncogene by screening with antibodies for phosphotyrosine, Proc Natl Acad Sci USA, 84, 1345, 10.1073/pnas.84.5.1345 · DOI
- Choo, 1986, Vectors for expression and amplification of cDNA in mammalian cells: expression of rat phenylalanine hydroxylase, DNA, 5, 529, 10.1089/dna.1.1986.5.529 · DOI
- Patwardhan, 1991, EGR3, a novel member of the Egr family of genes encoding immediate–early transcription factors, Oncogene, 6, 917
- Xu, 1994, Differing structural requirements for GTPase-activating protein responsiveness and NADPH oxidase activation by Rac, J Biol Chem, 269, 23569, 10.1016/S0021-9258(17)31553-3 · DOI · Paper page
- Bruder, 1992, Serum-, TPA-, and Ras-induced expression from Ap-1/Ets-driven promoters requires Raf-1 kinase, Genes Dev, 6, 545, 10.1101/gad.6.4.545 · DOI
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Cited by
Whitmarsh, A. J., & Davis, R. J. (1996) · Journal of Molecular Medicine · doi:10.1007/s001090050063 · Cited by 1,543
Shutes, A., Onesto, C., Picard, V., Leblond, B., Schweighoffer, F., & Der, C. J. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m703571200 · Cited by 336
Thomas, E. K., Cancelas, J. A., Chae, H.-D., Cox, A. D., Keller, P. J., Perrotti, D., Neviani, P., Druker, B. J., Setchell, K. D. R., Zheng, Y., et al. (2007) · Cancer Cell · doi:10.1016/j.ccr.2007.10.015 · Cited by 147
Metadata
- Authors
- Renshaw, M. W., Lea-Chou, E., & Wang, J. Y. J.
- Venue
- Current Biology
- Publisher
- Elsevier BV
- Published
- 1996-01
- Volume
- 6
- Issue
- 1
- Pages
- 76-83
- ISSN
- 0960-9822
- Cited by
- 66
- References
- 0
- Language
- en
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