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Cited by 492

The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.

Is protein folding hierarchic? I. Local structure and peptide folding

Open access
Baldwin, Robert L., Rose, George D.·1999·Trends in Biochemical Sciences

Abstract

The folding reactions of some small proteins show clear evidence of a hierarchic process, whereas others, lacking detectable intermediates, do not. Nevertheless, we argue that both classes fold hierarchically and that folding begins locally. If this is the case, then the secondary structure of a protein is determined largely by local sequence information. Experimental data and theoretical considerations support this argument. Part I of this article reviews the relationship between secondary structures in proteins and their counterparts in peptides.

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Metadata

Authors
Baldwin, R. L., & Rose, G. D.
Venue
Trends in Biochemical Sciences
Publisher
Elsevier BV
Published
1999-01
Volume
24
Issue
1
Pages
26-33
ISSN
0968-0004 (ISSN-L)
OpenAlex
W2105880172
Cited by
492
References
3
FWCI
3.02
Type
journal article
Language
en
Open access
hybrid

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CoChat. (2026). Citation check: Is protein folding hierarchic? I. Local structure and peptide folding. https://app.cochat.ai/papers/10.1016/s0968-0004(98)01346-2
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Baldwin, R. L., & Rose, G. D. (1999). Is protein folding hierarchic? I. Local structure and peptide folding. Trends in Biochemical Sciences. https://doi.org/10.1016/s0968-0004(98)01346-2

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.