The DOI matches its Crossref record; 26 of the 26 references it cites were found in a registry or an index.
Optimized EPI for fMRI studies of the orbitofrontal cortex
Abstract
A common problem in gradient-echo echo planar imaging (EPI) is the occurrence of image distortions and signal losses caused by susceptibility gradients near air/tissue interfaces. Since EPI is frequently used for functional magnetic resonance imaging experiments based on the blood oxygenation level-dependent effect, functional studies of certain brain regions affected by susceptibility gradients, such as the temporal lobes and the orbitofrontal cortex, may be compromised. In this work a method for signal recovery in certain regions of the orbitofrontal cortex is presented. The influence of in-plane susceptibility gradients is reduced by optimization of the imaging slice orientation. Through-plane susceptibility gradients are partly compensated by means of a moderate preparation gradient pulse similar to z-shimming. In contrast to several other techniques proposed in the literature for reducing susceptibility effects, this method does not compromise the temporal resolution and is therefore applicable to event-related studies.
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“we have successfully used imaging in approximately the plane of the Sylvian fissure, which enables imaging of both the OFC and the medial temporal lobe, as set out in the previously published articles (Deichmann et al., 2002, 2003; Rolls et al., 2015b, 2020b).”
From The orbitofrontal cortex: reward, emotion and depression (2020) · cites this paper as Deichmann et al., 2003
In the citing paper
“The influence of in-plane susceptibility gradients in orbitofrontal regions was reduced by orienting image slices according to recommendations by [72].”
From What are you feeling? Using functional magnetic resonance imaging to assess the modulation of sensory and affective responses during empathy for pain (2007) · cites this paper as [72]
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Metadata
- Authors
- Deichmann, R., Gottfried, J. A., Hutton, C., & Turner, R.
- Affiliations
- Wellcome Centre for Human Neuroimaging (GB)
- Corresponding author
- Deichmann, R
- Venue
- NeuroImage
- Publisher
- Elsevier BV
- Published
- 2003-06
- Volume
- 19
- Issue
- 2
- Pages
- 430-441
- ISSN
- 1053-8119 (ISSN-L)
- OpenAlex
- W2007309426
- Cited by
- 821
- References
- 26
- Citations by year
- 2026: 8 · 2025: 20 · 2024: 17 · 2023: 22 · 2022: 29 · 2021: 47 · 2020: 37 · 2019: 33 · 2018: 57 · 2017: 51 · 2016: 52 · 2015: 52 · 2014: 52 · 2013: 61 · 2012: 32
- FWCI
- 18.24
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- NeuroImage (publishedVersion)
- PubMed (publishedVersion)
- UCL Discovery (University College London) (submittedVersion)
- Max Planck Digital Library (submittedVersion)
- MPG.PuRe (Max Planck Society) (submittedVersion)
- Funders
- Howard Hughes Medical Institute
- Wellcome Trust
- Topics
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Advanced MRI Techniques and Applications
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Advanced Neuroimaging Techniques and Applications
- Life Sciences › Neuroscience › Cognitive Neuroscience › Functional Brain Connectivity Studies
- Keywords
- echo planar imaging, orbitofrontal cortex, image distortion, air-tissue interface, event-related fMRI, temporal resolution
- MeSH terms
- Algorithms, Brain Mapping, Evoked Potentials, Frontal Lobe, Humans, Image Enhancement, Image Processing, Computer-Assisted, Magnetic Resonance Imaging, Mathematical Computing, Oxygen Consumption, Reference Values, Sensitivity and Specificity, Artifacts, Echo-Planar Imaging
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