The DOI matches its Crossref record; 64 of the 65 references it cites were found in a registry or an index.
Impact of depressive symptoms on adult asthma outcomes
Abstract
Background Psychological disorders, including depression, are common in adults with asthma. Although depression is treatable, its impact on longitudinal asthma outcomes is not clear.Objective To elucidate the impact of depressive symptoms on patient-centered outcomes and emergency health care use in adults with asthma.Methods We conducted a prospective cohort study of 743 adults with asthma who were recruited after hospitalization for asthma. Depressive symptoms were defined as having a score of 16 or more on the Center for Epidemiologic Studies Depression Scale. We examined the impact of depressive symptoms on patient-centered outcomes (validated severity-of-asthma score, Marks Asthma Quality of Life Questionnaire, and 12-Item Short-Form Health Survey physical component summary score) and on future emergency health care use for asthma ascertained from computerized databases.Results The prevalence of depressive symptoms was 18% (95% confidence interval [CI], 15%-21%) among adults with asthma. Depressive symptoms were associated with greater severity-of-asthma scores after controlling for age, sex, race/ ethnicity, educational attainment, and cigarette smoking (mean score increment, 2.6 points; 95% CI, 1.8-3.4 points). Furthermore, depressive symptoms were associated with poorer asthma-specific quality of life (mean score increment, 19.9 points; 95% CI, 17.7-22.1 points) and poorer physical health status (mean score decrement, 3.7 points; 95% CI, 1.5-5.8 points). Depressive symptoms were associated with a greater longitudinal risk of hospitalization for asthma (hazard ratio, 1.34; 95% CI, 0.98-1.84). After controlling for differences in preventive care for asthma, the relationship was stronger (hazard ratio, 1.45; 95% CI, 1.05-2.0).Conclusion Depressive symptoms are common in adults with asthma and are associated with poorer health outcomes, including greater asthma severity and risk of hospitalization for asthma.
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“Moreover, there is a robust relationship between depression and anxiety and poor outcomes in inflammatory diseases (Eisner et al., 2005; Satin et al., 2009).”
From Origin and function of stress-induced IL-6 in murine models (2020) · cites this paper as Eisner et al., 2005
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Cites
The CES-D Scale: A Self-Report Depression Scale for Research in the General Population
Radloff, L. S. (1977) · Applied Psychological Measurement · doi:10.1177/014662167700100306 · Cited by 53,267
(1992) · PubMed · Cited by 33,716
The MOS 36-ltem Short-Form Health Survey (SF-36): I. Conceptual Framework and Item Selection
Ware, J. E., & Sherbourne, C. D. (1992) · Medical Care · doi:10.1097/00005650-199206000-00002 · Cited by 30,033
Norman, G. R., Sloan, J. A., & Wyrwich, K. W. (2003) · Medical Care · doi:10.1097/01.mlr.0000062554.74615.4c · Cited by 4,700
Measuring Health: A Guide to Rating Scales and Questionnaires
McDowell, I., & Newell, C. (1987) · Cited by 4,207
Expert Panel Report 2: Guidelines for the Diagnosis and Management of Asthma
Program, P., & theDiagnosis, T. E. P. O. (1997) · Cited by 4,082
Partial residuals for the proportional hazards regression model
SCHOENFELD, D. (1982) · Biometrika · doi:10.1093/biomet/69.1.239 · Cited by 3,111
Ware, J. E., Kosinski, M. R., Bayliss, M. S., McHorney, C. A., Rogers, W. H., & Raczek, A. E. (1995) · PubMed · Cited by 1,734
Surveillance for asthma--United States, 1980-1999.
Mannino, D. M., Homa, D. M., Akinbami, L. J., Moorman, J. E., Gwynn, C., & Redd, S. C. (2002) · PubMed · Cited by 1,699
Krieger, N. R. (1992) · American Journal of Public Health · doi:10.2105/ajph.82.5.703 · Cited by 1,661
Research works printed but not linked: 3
- Mannino, 1998, Surveillance for asthma-United States, 1960–1995, MMWR Morb Mortal Wkly Rep, 47, 1
- Eisner, 2002, Intensive care unit admission for asthma: a marker of severe disease [abstract], Am J Respir Crit Care Med, 165, A121
- Cigarette smoking among adults-United States, 1997, 1999, MMWR Morb Mortal Wkly Rep, 48, 993
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Expert Panel Report 2: Guidelines for the Diagnosis and Management of Asthma
Program, P., & theDiagnosis, T. E. P. O. (1997) · Cited by 4,082
Katon, W., Lin, E. H. B., & Kroenke, K. (2007) · General Hospital Psychiatry · doi:10.1016/j.genhosppsych.2006.11.005 · Cited by 965
The inflammasome: Pathways linking psychological stress, depression, and systemic illnesses
Iwata, M., Ota, K. T., & Duman, R. S. (2013) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2012.12.008 · Cited by 580
Acute exacerbations of asthma: epidemiology, biology and the exacerbation‐prone phenotype
Dougherty, R. H., & Fahy, J. V. (2009) · Clinical & Experimental Allergy · doi:10.1111/j.1365-2222.2008.03157.x · Cited by 400
Origin and function of stress-induced IL-6 in murine models
Qing, H., Desrouleaux, R., Israni-Winger, K., Mineur, Y. S., Fogelman, N., Zhang, C., Rashed, S., Palm, N. W., Sinha, R., Picciotto, M. R., et al. (2020) · Cell · doi:10.1016/j.cell.2020.05.054 · Cited by 303
Metadata
- Authors
- Eisner, M. D., Katz, P. P., Lactao, G., & Iribarren, C.
- Affiliations
- University of California, San Francisco (US)
- Kaiser Permanente (US)
- Corresponding author
- Eisner, Mark D.
- Venue
- Annals of Allergy, Asthma & Immunology
- Publisher
- Elsevier BV
- Published
- 2005-05
- Volume
- 94
- Issue
- 5
- Pages
- 566-574
- ISSN
- 1081-1206 (ISSN-L)
- OpenAlex
- W2039110930
- Cited by
- 130
- References
- 65
- Citations by year
- 2025: 3 · 2024: 3 · 2023: 2 · 2022: 7 · 2021: 2 · 2020: 4 · 2019: 5 · 2018: 9 · 2017: 6 · 2016: 7 · 2015: 6 · 2014: 3 · 2013: 6 · 2012: 13
- FWCI
- 5.42
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Annals of Allergy Asthma & Immunology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Heart, Lung, and Blood Institute (K23HL004201, K23 HL-04201)
- Topics
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Asthma and respiratory diseases
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Chronic Obstructive Pulmonary Disease (COPD) Research
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Occupational exposure and asthma
- Keywords
- depressive symptoms, depression, asthma, asthma severity, asthma-specific quality of life, physical health status, emergency department visits, asthma hospitalization, patient-centered outcomes, psychological comorbidity
- MeSH terms
- Adult, Asthma, California, Depression, Female, Health Status, Hospitalization, Humans, Male, Prospective Studies, Quality of Life, Surveys and Questionnaires, Risk Factors, Cohort Studies, Prevalence
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